Nocturnal asthma and the importance of race/ethnicity and genetic ancestry

American Journal of Respiratory and Critical Care Medicine

Volumn 190, Issue 3, 2014, Pages 266-273

  Levin, Albert M ^a   Wang, Yun ^a   Wells, Karen E ^a   Padhukasahasram, Badri ^a   Yang, James J ^a   Burchard, Esteban G ^b,c   Williams, L Keoki ^a  

^a HENRY FORD HEALTH SYSTEM   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Asthma; Genetic ancestry; Lung function; Nocturnal symptoms; Race ethnicity

Indexed keywords

ADOLESCENT; ADULT; AFRICAN AMERICAN; ARTICLE; ELECTRONIC MEDICAL RECORD; ETHNICITY; EUROPEAN AMERICAN; FEMALE; FORCED EXPIRATORY VOLUME; GENETIC ANCESTRY; GENETIC ASSOCIATION; HOSPITALIZATION; HUMAN; LUNG FUNCTION; MAJOR CLINICAL STUDY; MALE; MEDICATION COMPLIANCE; NOCTURNAL ASTHMA; POPULATION; POPULATION GENETICS; PRIORITY JOURNAL; RACE; ASTHMA; BODY MASS; CAUCASIAN; CIRCADIAN RHYTHM; DRUG EFFECT; GENETICS; INHALATIONAL DRUG ADMINISTRATION; NOCTURNAL SYMPTOMS; PHARMACOGENETICS; PHENOTYPE; PHYSIOLOGY; QUESTIONNAIRE; RACE/ETHNICITY; SMOKING; STATISTICAL MODEL; STATISTICS; UNITED STATES;

BRONCHODILATING AGENT; SALBUTAMOL;

ASTHMA; GENETIC ANCESTRY; LUNG FUNCTION; NOCTURNAL SYMPTOMS; RACE/ETHNICITY;

ADMINISTRATION, INHALATION; ADULT; AFRICAN AMERICANS; ALBUTEROL; ASTHMA; BODY MASS INDEX; BRONCHODILATOR AGENTS; CIRCADIAN RHYTHM; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FORCED EXPIRATORY VOLUME; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LOGISTIC MODELS; MALE; MICHIGAN; PHARMACOGENETICS; PHENOTYPE; QUESTIONNAIRES; SMOKING;

EID: 84907299524     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201402-0204OC     Document Type: Article

References (48)

1. Centers for Disease Control and Prevention (CDC). Self-reported asthma prevalence and control among adults-United States, 2001. MMWR Morb Mortal Wkly Rep 2003;52:381-384.
2. Global Initiative for Asthma. Global Strategy Asthma Management and Prevention NHLBI/WHO Workshop Report, March 1993. Bethesda, MD: National Institutes of Health, National Heart, Lung, and Blood Institute; 1993. NIH publication 95-3659.
3. National Heart, Lung, and Blood Institute. Global Initiative for Asthma: Global Strategy for Asthma Management and Prevention 2002. Bethesda, MD: National Institutes of Health, National Heart, Lung, and Blood Institute; 2002. NIH publication 02-3659.
4. Tse SM, Tantisira K, Weiss ST. The pharmacogenetics and pharmacogenomics of asthma therapy. Pharmacogenomics J 2011; 11:383-392.
5. Turner-Warwick M. Epidemiology of nocturnal asthma. Am JMed 1988;85:6-8.
6. Diette GB, Markson L, Skinner EA, Nguyen TT, Algatt-Bergstrom P, Wu AW. Nocturnal asthma in children affects school attendance, school performance, and parents' work attendance. Arch Pediatr Adolesc Med 2000;154:923-928.
7. Calhoun WJ. Nocturnal asthma. Chest 2003;123:399S-405S.
8. Hetzel MR, Clark TJ, Branthwaite MA. Asthma: analysis of sudden deaths and ventilatory arrests in hospital. BMJ 1977;1:808-811.
9. Douglas NJ. Asthma at night. Clin Chest Med 1985;6:663-674.
10. Sutherland ER. Nocturnal asthma: underlying mechanisms and treatment. Curr Allergy Asthma Rep 2005;5:161-167.
11. Martin RJ, Cicutto LC, Ballard RD. Factors related to the nocturnal worsening of asthma. Am Rev Respir Dis 1990;141:33-38.
12. Irvin CG, Pak J, Martin RJ. Airway-parenchyma uncoupling in nocturnal asthma. Am J Respir Crit Care Med 2000;161:50-56.
13. Kraft M, Djukanovic R, Wilson S, Holgate ST, Martin RJ. Alveolar tissue inflammation in asthma. Am J Respir Crit Care Med 1996;154: 1505-1510.
14. Nadif R, Siroux V, Oryszczyn MP, Ravault C, Pison C, Pin I, Kauffmann F; Epidemiological study on the Genetics and Environment of Asthma (EGEA). Heterogeneity of asthma according to blood inflammatory patterns. Thorax 2009;64:374-380.
15. Mannino DM, Homa DM, Akinbami LJ, Moorman JE, Gwynn C, Redd SC. Surveillance for asthma-United States, 1980-1999. MMWR Surveill Summ 2002;51:1-13.
16. Miller JE. The effects of race/ethnicity and income on early childhood asthma prevalence and health care use. Am J Public Health 2000;90: 428-430.
17. Centers for Disease Control and Prevention (CDC). Asthma mortality and hospitalization among children and young adults-United States, 1980-1993. MMWR Morb Mortal Wkly Rep 1996;45:350-353.
18. Nathan RA, Sorkness CA, Kosinski M, Schatz M, Li JT, Marcus P, Murray JJ, Pendergraft TB. Development of the asthma control test: a survey for assessing asthma control. J Allergy Clin Immunol 2004; 113:59-65.
19. Miller MR, Hankinson J, Brusasco V, Burgos F, Casaburi R, Coates A, Crapo R, Enright P, van der Grinten CP, Gustafsson P, et al.; ATS/ERS Task Force. Standardisation of spirometry. Eur Respir J 2005;26:319-338.
20. Hoffmann TJ, Kvale MN, Hesselson SE, Zhan Y, Aquino C, Cao Y, Cawley S, Chung E, Connell S, Eshragh J, et al. Next generation genome-wide association tool: design and coverage of a highthroughput European-optimized SNP array. Genomics 2011;98:79-89.
21. Sankararaman S, Sridhar S, Kimmel G, Halperin E. Estimating local ancestry in admixed populations. Am J Hum Genet 2008;82:290-303.
22. Pasaniuc B, Sankararaman S, Kimmel G, Halperin E. Inference of locusspecific ancestry in closely related populations. Bioinformatics 2009;25:i213-i221.
23. Imai K, Keele L, Tingley D. A general approach to causal mediation analysis. Psychol Methods 2010;15:309-334.
24. Imai K, Keele L, Yamamoto T. Identification, inference, and sensitivity analysis for causal mediation effects. Stat Sci 2010;25:51-71.
25. Williams LK, Peterson EL, Wells K, Ahmedani BK, Kumar R, Burchard EG, Chowdhry VK, Favro D, Lanfear DE, Pladevall M. Quantifying the proportion of severe asthma exacerbations attributable to inhaled corticosteroid nonadherence. J Allergy Clin Immunol 2011;128: 1185-1191.e2.
26. Tingley D, Yamamoto T, Hirose K, Keele L, Imai K. mediation: R package for causal mediation analysis. R package version 4.3.1. 2013 [accessed 2013 Dec 11]. Available from: http://CRAN.R-project.org/package=mediation
27. R Core Team. R: A language and environment for statistical computing. Vienna, Austria: R Foundation for Statistical Computing; 2013.
28. Trochtenberg DS, BeLue R, Piphus S, Washington N. Differing reports of asthma symptoms in African Americans and Caucasians. J Asthma 2008;45:165-170.
29. Greenberg H, Cohen RI. Nocturnal asthma. Curr Opin Pulm Med 2012; 18:57-62.
30. Kumar R, Seibold MA, Aldrich MC, Williams LK, Reiner AP, Colangelo L, Galanter J, Gignoux C, Hu D, Sen S, et al. Genetic ancestry in lung-function predictions. N Engl J Med 2010;363:321-330.
31. Klei L, Luca D, Devlin B, Roeder K. Pleiotropy and principal components of heritability combine to increase power for association analysis. Genet Epidemiol 2008;32:9-19.
32. O'Reilly PF, Hoggart CJ, Pomyen Y, Calboli FC, Elliott P, Jarvelin MR, Coin LJ. MultiPhen: joint model of multiple phenotypes can increase discovery in GWAS. PLoS ONE 2012;7:e34861.
33. National Asthma Education and Prevention Program. Expert Panel Report 3 (EPR-3): Guidelines for the Diagnosis and Management of Asthma-Summary Report 2007. J Allergy Clin Immunol 2007;120: S94-S138.
34. Wells KE, Peterson EL, Ahmedani BK, Severson RK, Gleason-Comstock J, Williams LK. The relationship between combination inhaled corticosteroid and long-acting beta-agonist use and severe asthma exacerbations in a diverse population. J Allergy Clin Immunol 2012;129:1274-1279.e2.
35. Lemanske RF Jr, Mauger DT, Sorkness CA, Jackson DJ, Boehmer SJ, Martinez FD, Strunk RC, Szefler SJ, Zeiger RS, Bacharier LB, et al.; Childhood Asthma Research and Education (CARE) Network of the National Heart, Lung, and Blood Institute. Step-up therapy for children with uncontrolled asthma receiving inhaled corticosteroids. N Engl J Med 2010;362:975-985.
36. Nelson HS, Weiss ST, Bleecker ER, Yancey SW, Dorinsky PM; SMART Study Group. The Salmeterol Multicenter Asthma Research Trial: a comparison of usual pharmacotherapy for asthma or usual pharmacotherapy plus salmeterol. Chest 2006;129:15-26.
37. Williams LK, Joseph CL, Peterson EL, Moon C, Xi H, Krajenta R, Johnson R, Wells K, Booza JC, Tunceli K, et al. Race-ethnicity, crime, and other factors associated with adherence to inhaled corticosteroids. J Allergy Clin Immunol 2007;119:168-175.
38. Yaeger R, Avila-Bront A, Abdul K, Nolan PC, Grann VR, Birchette MG, Choudhry S, Burchard EG, Beckman KB, Gorroochurn P, et al. Comparing genetic ancestry and self-described race in African Americans born in the United States and in Africa. Cancer Epidemiol Biomarkers Prev 2008;17:1329-1338.
39. Parra EJ, Marcini A, Akey J, Martinson J, Batzer MA, Cooper R, Forrester T, Allison DB, Deka R, Ferrell RE, et al. Estimating African American admixture proportions by use of population-specific alleles. Am J Hum Genet 1998;63:1839-1851.
40. Julien JY, Martin JG, Ernst P, Olivenstein R, Hamid Q, Lemière C, Pepe C, Naor N, Olha A, Kimoff RJ. Prevalence of obstructive sleep apneahypopnea in severe versus moderate asthma. J Allergy Clin Immunol 2009;124:371-376.
41. Gislason T, Janson C, Vermeire P, Plaschke P, Björnsson E, Gislason D, Boman G. Respiratory symptoms and nocturnal gastroesophageal reflux: a population-based study of young adults in three European countries. Chest 2002;121:158-163.
42. Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med 2002;165:1217-1239.
43. El-Serag HB, Graham DY, Satia JA, Rabeneck L. Obesity is an independent risk factor for GERD symptoms and erosive esophagitis. Am J Gastroenterol 2005;100:1243-1250.
44. Litonjua AA, Celedón JC, Hausmann J, Nikolov M, Sredl D, Ryan L, Platts-Mills TA, Weiss ST, Gold DR. Variation in total and specific IgE: effects of ethnicity and socioeconomic status. J Allergy Clin Immunol 2005;115:751-757.
45. Yang JJ, Burchard EG, Choudhry S, Johnson CC, Ownby DR, Favro D, Chen J, Akana M, Ha C, Kwok PY, et al. Differences in allergic sensitization by self-reported race and genetic ancestry. J Allergy Clin Immunol 2008;122:820-827.e9.
46. Gruchalla RS, Pongracic J, Plaut M, Evans R III, Visness CM, Walter M, Crain EF, Kattan M, Morgan WJ, Steinbach S, et al. Inner City Asthma Study: relationships among sensitivity, allergen exposure, and asthma morbidity. J Allergy Clin Immunol 2005;115:478-485.
47. Rosenstreich DL, Eggleston P, Kattan M, Baker D, Slavin RG, Gergen P, Mitchell H, McNiff-Mortimer K, Lynn H, Ownby D, et al. The role of cockroach allergy and exposure to cockroach allergen in causing morbidity among inner-city children with asthma. N Engl J Med 1997; 336:1356-1363.
48. Hankinson JL, Odencrantz JR, Fedan KB. Spirometric reference values from a sample of the general U.S. population. Am J Respir Crit Care Med 1999;159:179-187.