Detection and preliminary evaluation of circulating tumor cells in the peripheral blood of patients with eight types of cancer using a telomerase-specific adenovirus

Oncology Reports

Volumn 32, Issue 5, 2014, Pages 1772-1778

  Yabusaki, Mina ^a,b   Sato, Jun ^a,b   Kohyama, Atsushi ^b   Kojima, Takashi ^b   Nobuoka, Daisuke ^b,c   Yoshikawa, Toshiaki ^b   Sawada, Yu ^b   Murakami, Katsuhiro ^a   Gohda, Keigo ^a   Okegawa, Takatsugu ^d   Nakamura, Masaru ^e   Takamatsu, Kiyoshi ^e   Ito, Masaaki ^b   Kaneko, Kazuhiro ^b   Nakatsura, Tetsuya ^b  

^a SYSMEX CORPORATION   (Japan)

^b NATIONAL CANCER CENTER HOSPITAL EAST   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

^d KYORIN UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e TOKYO DENTAL COLLEGE   (Japan)

Author keywords

Adenovirus; Circulating tumor cells; OBP 401; Telomerase

Indexed keywords

CD13 ANTIBODY; CD14 ANTIBODY; CD14 ANTIGEN; CD15 ANTIBODY; CD15 ANTIGEN; CD19 ANTIBODY; CD19 ANTIGEN; CD2 ANTIBODY; CD2 ANTIGEN; CD203C ANTIBODY; CD203C ANTIGEN; CD45 ANTIBODY; CD45 ANTIGEN; GREEN FLUORESCENT PROTEIN; LEUKOCYTE ANTIBODY; LEUKOCYTE ANTIGEN; MICROSOMAL AMINOPEPTIDASE; TELOMERASE; UNCLASSIFIED DRUG; ANTIBODY; HYBRID PROTEIN;

ADENOVIRUS; ADENOVIRUS OBP 401; ADULT; AGED; ANALYTIC METHOD; ANTIBODY LABELING; ANTIGEN ANTIBODY REACTION; ARTICLE; BLOOD ANALYSIS; BLOOD SAMPLING; CANCER DIAGNOSIS; CANCER STAGING; CELL DETECTION; CELL ISOLATION; CELL SELECTION; CELL SIZE; CIRCULATING TUMOR CELL; COLON CANCER; CONTROLLED STUDY; CORRELATIONAL STUDY; DIAGNOSTIC TEST ACCURACY STUDY; ENDOMETRIUM CANCER; ESOPHAGUS CANCER; EVALUATION STUDY; FALSE POSITIVE RESULT; FEMALE; FLUORESCENCE ANALYSIS; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; LEUKOCYTE; LIVER CANCER; MAJOR CLINICAL STUDY; MALE; MONOCYTE; ONCOVIRINAE; PANCREAS CANCER; PROCEDURES CONCERNING CELLS; PROMOTER REGION; PROSTATE CANCER; STOMACH CANCER; UTERINE CERVIX CANCER; VIRUS CELL INTERACTION; VIRUS GENOME; VIRUS RECOMBINANT; VIRUS STRAIN; ADENOVIRIDAE; BLOOD; DIAGNOSTIC TEST; DIAGNOSTIC USE; GENETICS; METABOLISM; MIDDLE AGED; NEOPLASMS; PATHOLOGY; PROCEDURES; REPRODUCIBILITY; TUMOR EMBOLISM; VERY ELDERLY;

ADENOVIRIDAE; AGED; AGED, 80 AND OVER; ANTIBODIES; ANTIGENS, CD; DIAGNOSTIC TESTS, ROUTINE; FEMALE; HUMANS; MALE; MIDDLE AGED; NEOPLASMS; NEOPLASTIC CELLS, CIRCULATING; RECOMBINANT FUSION PROTEINS; REPRODUCIBILITY OF RESULTS; TELOMERASE;

EID: 84907285388     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2014.3436     Document Type: Article

References (22)

1. Parkinson DR, Dracopoli N, Petty BG, Compton C, Cristofanilli M, Deisseroth A, Hayes DF, Kapke G, Kumar P, Lee JSH, Liu MC, McCormack R, Mikulski S, Nagahara L, Pantel K, Pearson-White S, Punnoose EA, Roadcap LT, Schade AE, Scher HI, Sigman CC and Kelloff GJ: Considerations in the development of circulating tumor cell technology for clinical use. J Transl Med 10: 138, 2012.
2. Cohen SJ, Punt CJ, Iannotti N, Saidman BH, Sabbath KD, Gabrail NY, Picus J, Morse M, Mitchell E, Miller MC, Doyle GV, Tissing H, Terstappen LW and Meropol NJ: Relationship of circulating tumor cells to tumor response, progression-free survival, and overall survival in patients with metastatic colorectal cancer. J Clin Oncol 26: 3213-3221, 2008.
3. Riethdorf S, Fritsche H, Müller V, Rau T, Schindlbeck C, Rack B, Janni W, Coith C, Beck K, Jänicke F, Jackson S, Gornet T, Cristofanilli M and Pantel K: Detection of circulating tumor cells in peripheral blood of patients with metastatic breast cancer: a validation study of the CellSearch system. Clin Cancer Res 13: 920-928, 2007.
4. Davis JW, Nakanishi H, Kumar VS, Bhadkamkar VA, McCormack R, Fritsche HA, Handy B, Gornet T and Babaian RJ: Circulating tumor cells in peripheral blood samples from patients with increased serum prostate specific antigen: initial results in early prostate cancer. J Urol 179: 2187-2191, 2008.
5. Pierga JY, Bidard FC, Mathiot C, Brain E, Delaloge S, Giachetti S, de Cremoux P, Salmon R, Vincent-Salomon A and Marty M: Circulating tumor cell detection predicts early metastatic relapse after neoadjuvant chemotherapy in large operable and locally advanced breast cancer in a phase II randomized trial. Clin Cancer Res 14: 7004-7010, 2008.
6. Hou JM, Greystoke A, Lancashire L, Cummings J, Ward T, Board R, Amir E, Hughes S, Krebs M, Hughes A, Ranson M, Lorigan P, Dive C and Blackhall FH: Evaluation of circulating tumor cells and serological cell death biomarkers in small cell lung cancer patients undergoing chemotherapy. Am J Pathol 175: 808-816, 2009.
7. Fujiwara T, Kagawa S, Kishimoto H, Endo Y, Hioki M, Ikeda Y, Sakai R, Urata Y, Tanaka N and Fujiwara T: Enhanced antitumor efficacy of telomerase-selective oncolytic adenoviral agent OBP-401 with docetaxel: preclinical evaluation of chemovirotherapy. Int J Cancer 119: 432-440, 2006.
8. Blackburn EH: Telomere states and cell fates. Nature 408: 53-56, 2000.
9. Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL, Coviello GM, Wright WE, Weinrich SL and Shay JW: Specific association of human telomerase activity with immortal cells and cancer. Science 266: 2011-2015, 1994.
10. Bilsland AE, Merron A, Vassaux G and Keith WN: Modulation of telomerase promoter tumor selectivity in the context of oncolytic adenoviruses. Cancer Res 67: 1299-1307, 2007.
11. Kojima T, Hashimoto Y, Watanabe Y, Kagawa S, Uno F, Kuroda S, Tazawa H, Kyo S, Mizuguchi H, Urata Y, Tanaka N and Fujiwara T: A simple biological imaging system for detecting viable human circulating tumor cells. J Clin Invest 119: 3172-3181, 2009.
12. Kim SJ, Masago A, Tamaki Y, Akazawa K, Tsukamoto F, Sato J, Ozawa T, Tsujino Y and Noguchi S: A novel approach using telomerase-specific replication-selective adenovirus for detection of circulating tumor cells in breast cancer patients. Breast Cancer Res Treat 128: 765-773, 2011.
13. Ito H, Inoue H, Sando N, Kimura S, Gohda K, Sato J, Murakami K, Ito S, Odaka N, Satodate H and Kudo SE: Prognostic impact of detecting viable circulating tumour cells in gastric cancer patients using a telomerase-specific viral agent: a prospective study. BMC Cancer 12: 346, 2012.
14. Igawa S, Gohda K, Fukui T, Ryuge S, Otani S, Masago A, Sato J, Murakami K, Maki S, Katono K, Takakura A, Sasaki J, Satoh Y and Masuda N: Circulating tumor cells as a prognostic factor in patients with small cell lung cancer. Oncol Lett 7: 1469-1473, 2014.
15. Takakura M, Kyo S, Nakamura M, Maida Y, Mizumoto Y, Bono Y, Zhang X, Hashimoto Y, Urata Y, Fujiwara T and Inoue M: Circulating tumour cells detected by a novel adenovirus-mediated system may be a potent therapeutic marker in gynaecological cancers. Br J Cancer 107: 448-454, 2012.
16. Vona G, Estepa L, Béroud C, Damotte D, Capron F, Nalpas B, Mineur A, Franco D, Lacour B, Pol S, Bréchot C and Paterlini-Bréchot P: Impact of cytomorphological detection of circulating tumor cells in patients with liver cancer. Hepatology 39: 792-797, 2004.
17. Vona G, Sabile A, Louha M, Sitruk V, Romana S, Schütze K, Capron F, Franco D, Pazzagli M, Vekemans M, Lacour B, Bréchot C and Paterlini-Bréchot P: Isolation by size of epithelial tumor cells: a new method for the immunomorphological and molecular characterization of circulating tumor cells. Am J Pathol 156: 57-63, 2000.
18. Lin HK, Zheng S, Williams AJ, Balic M, Groshen S, Scher HI, Fleisher M, Stadler W, Datar RH, Tai YC and Cote RJ: Portable filter-based microdevice for detection and characterization of circulating tumor cells. Clin Cancer Res 16: 5011-5018, 2010.
19. Zheng S, Lin HK, Lu B, Williams A, Datar R, Cote RJ and Tai YC: 3D microfilter device for viable circulating tumor cell (CTC) enrichment from blood. Biomed Microdevices 13: 203-213, 2011.
20. Kishimoto H, Kojima T, Watanabe Y, Kagawa S, Fujiwara T, Uno F, Teraishi F, Kyo S, Mizuguchi H, Hashimoto Y, Urata Y, Tanaka N and Fujiwara T: In vivo imaging of lymph node metastasis with telomerase-specific replication-selective adenovirus. Nat Med 12: 1213-1219, 2006.
21. Broccoli D, Young JW and de Lange T: Telomerase activity in normal and malignant hematopoietic cells. Proc Natl Acad Sci USA 92: 9082-9086, 1995.
22. Havenga MJ, Lemckert AA, Ophorst OJ, van Meijer M, Germeraad WT, Grimbergen J, van Den Doel MA, Vogels R, van Deutekom J, Janson AA, de Bruijn JD, Uytdehaag F, Quax PH, Logtenberg T, Mehtali M and Bout A: Exploiting the natural diversity in adenovirus tropism for therapy and prevention of disease. J Virol 76: 4612-4620, 2002.