-
1
-
-
84866510711
-
Mechanism of glioma-associated neovascularization
-
COI: 1:CAS:528:DC%2BC38XhsF2nsLfL, PID: 22858156
-
Hardee ME, Zagzag D. Mechanism of glioma-associated neovascularization. Am J Pathol. 2012;181:1126–41.
-
(2012)
Am J Pathol
, vol.181
, pp. 1126-1141
-
-
Hardee, M.E.1
Zagzag, D.2
-
2
-
-
17844371306
-
Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis
-
COI: 1:CAS:528:DC%2BD2MXjvV2qsLk%3D, PID: 15831232
-
Kaur B, Khwaja FW, Severson EA, Matheny SL, Brat DJ, Van Meir EG. Hypoxia and the hypoxia-inducible-factor pathway in glioma growth and angiogenesis. Neuro Oncol. 2005;7:134–53.
-
(2005)
Neuro Oncol
, vol.7
, pp. 134-153
-
-
Kaur, B.1
Khwaja, F.W.2
Severson, E.A.3
Matheny, S.L.4
Brat, D.J.5
Van Meir, E.G.6
-
3
-
-
65249131228
-
Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target
-
COI: 1:CAS:528:DC%2BD1MXkt1yitL4%3D, PID: 19357959
-
Jensen RL. Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target. J Neurooncol. 2009;92:317–35.
-
(2009)
J Neurooncol
, vol.92
, pp. 317-335
-
-
Jensen, R.L.1
-
4
-
-
0029761644
-
Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
-
COI: 1:CAS:528:DyaK28XltFKjsrc%3D, PID: 8756616
-
Forsythe JA, Jiang BH, Iyer NV, Agani F, Leung SW, Koos RD, et al. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1. Mol Cell Biol. 1996;16:4604–13.
-
(1996)
Mol Cell Biol
, vol.16
, pp. 4604-4613
-
-
Forsythe, J.A.1
Jiang, B.H.2
Iyer, N.V.3
Agani, F.4
Leung, S.W.5
Koos, R.D.6
-
5
-
-
33745784386
-
Mechanisms of angiogenesis in gliomas
-
COI: 1:CAS:528:DC%2BD28Xpt1ylt7Y%3D, PID: 16554966
-
Kargiotis O, Rao JS, Kyritsis AP. Mechanisms of angiogenesis in gliomas. J Neurooncol. 2006;78:281–93.
-
(2006)
J Neurooncol
, vol.78
, pp. 281-293
-
-
Kargiotis, O.1
Rao, J.S.2
Kyritsis, A.P.3
-
6
-
-
65549093775
-
Angiogenesis and anti-angiogenic molecularly targeted therapies in malignant gliomas
-
COI: 1:CAS:528:DC%2BD1MXot12ktro%3D, PID: 19439998
-
Argyriou AA, Giannopoulou E, Kalofonos HP. Angiogenesis and anti-angiogenic molecularly targeted therapies in malignant gliomas. Oncology. 2009;77:1–11.
-
(2009)
Oncology
, vol.77
, pp. 1-11
-
-
Argyriou, A.A.1
Giannopoulou, E.2
Kalofonos, H.P.3
-
7
-
-
0030249455
-
Quantifying regional hypoxia in human tumors with positron emission tomography of [18F]fluoromisonidazole: a pretherapy study of 37 patients
-
COI: 1:STN:280:DyaK2s%2FkslGntQ%3D%3D, PID: 8892467
-
Rasey JS, Koh WJ, Evans ML, Peterson LM, Lewellen TK, Graham MM, et al. Quantifying regional hypoxia in human tumors with positron emission tomography of [18F]fluoromisonidazole: a pretherapy study of 37 patients. Int J Radiat Oncol Biol Phys. 1996;36:417–26.
-
(1996)
Int J Radiat Oncol Biol Phys
, vol.36
, pp. 417-426
-
-
Rasey, J.S.1
Koh, W.J.2
Evans, M.L.3
Peterson, L.M.4
Lewellen, T.K.5
Graham, M.M.6
-
8
-
-
0026475672
-
Hypoxia in human gliomas: demonstration by PET with fluorine-18-fluoromisonidazole
-
COI: 1:STN:280:DyaK3s%2FpsV2isQ%3D%3D, PID: 1334136
-
Valk PE, Mathis CA, Prados MD, Gilbert JC, Budinger TF. Hypoxia in human gliomas: demonstration by PET with fluorine-18-fluoromisonidazole. J Nucl Med. 1992;33:2133–7.
-
(1992)
J Nucl Med
, vol.33
, pp. 2133-2137
-
-
Valk, P.E.1
Mathis, C.A.2
Prados, M.D.3
Gilbert, J.C.4
Budinger, T.F.5
-
9
-
-
58249121592
-
Complementary but distinct roles for MRI and 18F-fluoromisonidazole PET in the assessment of human glioblastomas
-
PID: 19091885
-
Swanson KR, Chakraborty G, Wang CH, Rockne R, Harpold HLP, Muzi M, et al. Complementary but distinct roles for MRI and 18F-fluoromisonidazole PET in the assessment of human glioblastomas. J Nucl Med. 2009;50:36–44.
-
(2009)
J Nucl Med
, vol.50
, pp. 36-44
-
-
Swanson, K.R.1
Chakraborty, G.2
Wang, C.H.3
Rockne, R.4
Harpold, H.L.P.5
Muzi, M.6
-
10
-
-
79953734435
-
Correlation of biological aggressiveness assessed by 11C-methionine PET and hypoxic burden assessed by 18F-fluoromisonidazole PET in newly diagnosed glioblastoma
-
COI: 1:CAS:528:DC%2BC3MXhs1Gjs7o%3D, PID: 21072512
-
Kawai N, Maeda Y, Kudomi N, Miyake K, Okada M, Yamamoto Y, et al. Correlation of biological aggressiveness assessed by 11C-methionine PET and hypoxic burden assessed by 18F-fluoromisonidazole PET in newly diagnosed glioblastoma. Eur J Nucl Med Mol Imaging. 2011;38:441–50.
-
(2011)
Eur J Nucl Med Mol Imaging
, vol.38
, pp. 441-450
-
-
Kawai, N.1
Maeda, Y.2
Kudomi, N.3
Miyake, K.4
Okada, M.5
Yamamoto, Y.6
-
11
-
-
0037700084
-
Methyl-[11C]- l-methionine uptake as measured by positron emission tomography correlates to microvessel density in patients with glioma
-
COI: 1:CAS:528:DC%2BD3sXjvF2lsL0%3D, PID: 12692687
-
Kracht LW, Friese M, Herholz K, Schroeder R, Bauer B, Jacobs A, et al. Methyl-[11C]- l-methionine uptake as measured by positron emission tomography correlates to microvessel density in patients with glioma. Eur J Nucl Med Mol Imaging. 2003;30:868–73.
-
(2003)
Eur J Nucl Med Mol Imaging
, vol.30
, pp. 868-873
-
-
Kracht, L.W.1
Friese, M.2
Herholz, K.3
Schroeder, R.4
Bauer, B.5
Jacobs, A.6
-
12
-
-
77956060344
-
Correlation of L-methyl-11C-methionine (MET) uptake with L-type amino acid transporter 1 in human gliomas
-
COI: 1:CAS:528:DC%2BC3cXhtVGmtLbO, PID: 20091333
-
Okubo S, Zhen HN, Kawai N, Nishiyama Y, Haba R, Tamiya T. Correlation of L-methyl-11C-methionine (MET) uptake with L-type amino acid transporter 1 in human gliomas. J Neurooncol. 2010;99:217–25.
-
(2010)
J Neurooncol
, vol.99
, pp. 217-225
-
-
Okubo, S.1
Zhen, H.N.2
Kawai, N.3
Nishiyama, Y.4
Haba, R.5
Tamiya, T.6
-
13
-
-
33645969631
-
Correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in gliomas using 18F-fluoromisonidazole, 18F-FDG PET, and immunohistochemical studies
-
COI: 1:CAS:528:DC%2BD28Xlt1Kms7g%3D, PID: 16513609
-
Cher LM, Murone C, Lawrentschuk N, Ramdave S, Papenfuss A, Hannah A, et al. Correlation of hypoxic cell fraction and angiogenesis with glucose metabolic rate in gliomas using 18F-fluoromisonidazole, 18F-FDG PET, and immunohistochemical studies. J Nucl Med. 2006;47:410–8.
-
(2006)
J Nucl Med
, vol.47
, pp. 410-418
-
-
Cher, L.M.1
Murone, C.2
Lawrentschuk, N.3
Ramdave, S.4
Papenfuss, A.5
Hannah, A.6
-
14
-
-
52049120148
-
Regional hypoxia in glioblastoma multiforme quantified with [18F]fluoromisonidazole positron emission tomography before radiotherapy: correlation with time to progression and survival
-
COI: 1:CAS:528:DC%2BD1cXlsV2qtr8%3D, PID: 18451225
-
Spence AM, Muzi M, Swanson KR, O’Sullivan F, Rockhill JK, Rajendran JG, et al. Regional hypoxia in glioblastoma multiforme quantified with [18F]fluoromisonidazole positron emission tomography before radiotherapy: correlation with time to progression and survival. Clin Cancer Res. 2008;14:2623–30.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 2623-2630
-
-
Spence, A.M.1
Muzi, M.2
Swanson, K.R.3
O’Sullivan, F.4
Rockhill, J.K.5
Rajendran, J.G.6
-
15
-
-
84893173949
-
Update on anti-angiogenic treatment for malignant gliomas
-
PID: 24510742
-
de Groot JF, Mandel JJ. Update on anti-angiogenic treatment for malignant gliomas. Curr Oncol Rep. 2014;16:380. doi:10.1007/s11912-014-0380-6.
-
(2014)
Curr Oncol Rep
, vol.16
, pp. 380
-
-
de Groot, J.F.1
Mandel, J.J.2
-
16
-
-
84860833963
-
Hypoxia assessed by 18F-fluoromisonidazole positron emission tomography in newly diagnosed gliomas
-
COI: 1:CAS:528:DC%2BC38XpvFeqsr4%3D, PID: 22422099
-
Yamamoto Y, Maeda Y, Kawai N, Kudomi N, Aga F, Ono Y, et al. Hypoxia assessed by 18F-fluoromisonidazole positron emission tomography in newly diagnosed gliomas. Nucl Med Commun. 2012;33:621–5.
-
(2012)
Nucl Med Commun
, vol.33
, pp. 621-625
-
-
Yamamoto, Y.1
Maeda, Y.2
Kawai, N.3
Kudomi, N.4
Aga, F.5
Ono, Y.6
-
17
-
-
27144504703
-
Fully automated synthesis of [18F]fluoromisonidazole using a conventional [18F]FDG module
-
COI: 1:CAS:528:DC%2BD2MXhtFKhsbzP, PID: 16253816
-
Oh SJ, Chi DY, Mosdzianowski C, Kim JY, Gil HS, Kang SH, et al. Fully automated synthesis of [18F]fluoromisonidazole using a conventional [18F]FDG module. Nucl Med Biol. 2005;32:899–905.
-
(2005)
Nucl Med Biol
, vol.32
, pp. 899-905
-
-
Oh, S.J.1
Chi, D.Y.2
Mosdzianowski, C.3
Kim, J.Y.4
Gil, H.S.5
Kang, S.H.6
-
18
-
-
39149124801
-
Identification of 14-3-3 protein isoforms in human astrocytoma by immunohistochemistry
-
COI: 1:CAS:528:DC%2BD1cXitVeguro%3D, PID: 18242847
-
Cao L, Cao W, Zhang W, Lin H, Yang X, Zhen H, et al. Identification of 14-3-3 protein isoforms in human astrocytoma by immunohistochemistry. Neurosci Lett. 2008;432:94–9.
-
(2008)
Neurosci Lett
, vol.432
, pp. 94-99
-
-
Cao, L.1
Cao, W.2
Zhang, W.3
Lin, H.4
Yang, X.5
Zhen, H.6
-
19
-
-
84862587185
-
18F-Fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomas
-
COI: 1:CAS:528:DC%2BC38XlvVShsLw%3D, PID: 22307533
-
Hirata K, Terasaka S, Shiga T, Hattori N, Magota K, Kobayashi H, et al. 18F-Fluoromisonidazole positron emission tomography may differentiate glioblastoma multiforme from less malignant gliomas. Eur J Nucl Med Mol Imaging. 2012;39:760–70.
-
(2012)
Eur J Nucl Med Mol Imaging
, vol.39
, pp. 760-770
-
-
Hirata, K.1
Terasaka, S.2
Shiga, T.3
Hattori, N.4
Magota, K.5
Kobayashi, H.6
-
20
-
-
2942707871
-
Hypoxia-inducible factor 1alpha/vascular endothelial growth factor axis in astrocytomas. Associations with microvessel morphometry, proliferation and prognosis
-
COI: 1:CAS:528:DC%2BD2cXlslymtbc%3D, PID: 15175080
-
Korkolopoulou P, Patsouris E, Konstantinidou AE, Pavlopoulos PM, Kavantzas N, Boviatsis E, et al. Hypoxia-inducible factor 1alpha/vascular endothelial growth factor axis in astrocytomas. Associations with microvessel morphometry, proliferation and prognosis. Neuropathol Appl Neurobiol. 2004;30:267–78.
-
(2004)
Neuropathol Appl Neurobiol
, vol.30
, pp. 267-278
-
-
Korkolopoulou, P.1
Patsouris, E.2
Konstantinidou, A.E.3
Pavlopoulos, P.M.4
Kavantzas, N.5
Boviatsis, E.6
-
21
-
-
79952187104
-
Hypoxia-inducible factor 1α expression is a prognostic biomarker in patients with astrocytic tumors associated with necrosis on MR image
-
COI: 1:CAS:528:DC%2BC3MXit1ygtLs%3D, PID: 20596750
-
Mashiko R, Takano S, Ishikawa E, Yamamoto T, Nakai K, Matsumura A. Hypoxia-inducible factor 1α expression is a prognostic biomarker in patients with astrocytic tumors associated with necrosis on MR image. J Neurooncol. 2011;102:43–50.
-
(2011)
J Neurooncol
, vol.102
, pp. 43-50
-
-
Mashiko, R.1
Takano, S.2
Ishikawa, E.3
Yamamoto, T.4
Nakai, K.5
Matsumura, A.6
-
22
-
-
52049107208
-
Hypoxia-regulated protein expression, patient characteristics, and preoperative imaging as predictors of survival in adults with glioblastoma multiforme
-
PID: 18618497
-
Flynn JR, Wang L, Gillespie DL, Stoddard GJ, Reid JK, Owens J, et al. Hypoxia-regulated protein expression, patient characteristics, and preoperative imaging as predictors of survival in adults with glioblastoma multiforme. Cancer. 2008;113:1032–42.
-
(2008)
Cancer
, vol.113
, pp. 1032-1042
-
-
Flynn, J.R.1
Wang, L.2
Gillespie, D.L.3
Stoddard, G.J.4
Reid, J.K.5
Owens, J.6
-
23
-
-
0034757675
-
Vascular endothelial growth factor expression correlates with tumour grade and vascularity in gliomas
-
COI: 1:STN:280:DC%2BD3MngvFGgtQ%3D%3D, PID: 11683943
-
Chaudhry IH, O’Donovan DG, Brenchley PEC, Reid H, Roberts ISD. Vascular endothelial growth factor expression correlates with tumour grade and vascularity in gliomas. Histopathology. 2001;39:409–15.
-
(2001)
Histopathology
, vol.39
, pp. 409-415
-
-
Chaudhry, I.H.1
O’Donovan, D.G.2
Brenchley, P.E.C.3
Reid, H.4
Roberts, I.S.D.5
-
24
-
-
26944445860
-
Angiogenesis of glioma: evaluation of ultrastructural characteristics of microvessels and tubular bodies (Weibel-Palade) in endothelial cells and immunohistochemical findings with VEGF and p53 protein
-
PID: 16158178
-
Miyagami M, Katayama Y. Angiogenesis of glioma: evaluation of ultrastructural characteristics of microvessels and tubular bodies (Weibel-Palade) in endothelial cells and immunohistochemical findings with VEGF and p53 protein. Med Mol Morphol. 2005;38:36–42.
-
(2005)
Med Mol Morphol
, vol.38
, pp. 36-42
-
-
Miyagami, M.1
Katayama, Y.2
-
25
-
-
84863796187
-
Bevacizumab for the treatment of high-grade glioma
-
COI: 1:CAS:528:DC%2BC38XhtVemurvM, PID: 22663137
-
Khasraw M, Simeonovic M, Grommes C. Bevacizumab for the treatment of high-grade glioma. Expert Opin Biol Ther. 2012;12:1101–11.
-
(2012)
Expert Opin Biol Ther
, vol.12
, pp. 1101-1111
-
-
Khasraw, M.1
Simeonovic, M.2
Grommes, C.3
-
26
-
-
79951984402
-
Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme
-
COI: 1:CAS:528:DC%2BC3MXhvVahtb0%3D, PID: 21135282
-
Lai A, Tran A, Nghiemphu PL, Pope WB, Solis OE, Selch M, et al. Phase II study of bevacizumab plus temozolomide during and after radiation therapy for patients with newly diagnosed glioblastoma multiforme. J Clin Oncol. 2011;29:142–8.
-
(2011)
J Clin Oncol
, vol.29
, pp. 142-148
-
-
Lai, A.1
Tran, A.2
Nghiemphu, P.L.3
Pope, W.B.4
Solis, O.E.5
Selch, M.6
-
27
-
-
11144337759
-
Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators
-
PID: 15618010
-
Déry MA, Michaud MD, Richard DE. Hypoxia-inducible factor 1: regulation by hypoxic and non-hypoxic activators. Int J Biochem Cell Biol. 2005;37:535–40.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 535-540
-
-
Déry, M.A.1
Michaud, M.D.2
Richard, D.E.3
-
28
-
-
48649095925
-
The pervasive presence of fluctuating oxygenation in tumors
-
PID: 18632635
-
Cárdenas-Navia LI, Mace D, Richardson RA, Wilson DF, Shan S, Dewhirst MW. The pervasive presence of fluctuating oxygenation in tumors. Cancer Res. 2008;68:5812–9.
-
(2008)
Cancer Res
, vol.68
, pp. 5812-5819
-
-
Cárdenas-Navia, L.I.1
Mace, D.2
Richardson, R.A.3
Wilson, D.F.4
Shan, S.5
Dewhirst, M.W.6
-
29
-
-
70549102512
-
Relationships between cycling hypoxia, HIF-1, angiogenesis and oxidative stress
-
COI: 1:CAS:528:DC%2BD1MXhsFCgurvP, PID: 19929412
-
Dewhirst MW. Relationships between cycling hypoxia, HIF-1, angiogenesis and oxidative stress. Radiat Res. 2009;172:653–65.
-
(2009)
Radiat Res
, vol.172
, pp. 653-665
-
-
Dewhirst, M.W.1
-
30
-
-
0035347260
-
Induction of HIF-1alpha in response to hypoxia is instantaneous
-
COI: 1:CAS:528:DC%2BD3MXlvVOrtLs%3D, PID: 11344124
-
Jewell UR, Kvietikova I, Scheid A, Bauer C, Wenger RH, Gassmann M. Induction of HIF-1alpha in response to hypoxia is instantaneous. FASEB J. 2001;15:1312–4.
-
(2001)
FASEB J
, vol.15
, pp. 1312-1314
-
-
Jewell, U.R.1
Kvietikova, I.2
Scheid, A.3
Bauer, C.4
Wenger, R.H.5
Gassmann, M.6
-
31
-
-
0035936886
-
HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation
-
COI: 1:CAS:528:DC%2BD3MXhsFShs7s%3D, PID: 11226425
-
Berra E, Richard DE, Gothié E, Pouysségur J. HIF-1-dependent transcriptional activity is required for oxygen-mediated HIF-1alpha degradation. FEBS Lett. 2001;491:85–90.
-
(2001)
FEBS Lett
, vol.491
, pp. 85-90
-
-
Berra, E.1
Richard, D.E.2
Gothié, E.3
Pouysségur, J.4
-
32
-
-
0035159670
-
HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia
-
COI: 1:CAS:528:DC%2BD3MXoslSisbs%3D, PID: 11689469
-
Stroka DM, Burkhardt T, Desbaillets I, Wenger RH, Neil DA, Bauer C, et al. HIF-1 is expressed in normoxic tissue and displays an organ-specific regulation under systemic hypoxia. FASEB J. 2001;15:2445–53.
-
(2001)
FASEB J
, vol.15
, pp. 2445-2453
-
-
Stroka, D.M.1
Burkhardt, T.2
Desbaillets, I.3
Wenger, R.H.4
Neil, D.A.5
Bauer, C.6
-
33
-
-
0037847453
-
Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas
-
PID: 12758238
-
Nordsmark M, Loncaster J, Aquino-Parsons C, Chou SC, Ladekarl M, Havsteen H, et al. Measurements of hypoxia using pimonidazole and polarographic oxygen-sensitive electrodes in human cervix carcinomas. Radiother Oncol. 2003;67:35–44.
-
(2003)
Radiother Oncol
, vol.67
, pp. 35-44
-
-
Nordsmark, M.1
Loncaster, J.2
Aquino-Parsons, C.3
Chou, S.C.4
Ladekarl, M.5
Havsteen, H.6
-
34
-
-
0038642530
-
Tumour oxygenation assessed by 18F-fluoromisonidazole PET and polarographic needle electrodes in human soft tissue tumours
-
COI: 1:CAS:528:DC%2BD3sXlsVajsbo%3D, PID: 12865184
-
Bentzen L, Keiding S, Nordsmark M, Falborg L, Hansen SB, Keller J, et al. Tumour oxygenation assessed by 18F-fluoromisonidazole PET and polarographic needle electrodes in human soft tissue tumours. Radiother Oncol. 2003;67:339–44.
-
(2003)
Radiother Oncol
, vol.67
, pp. 339-344
-
-
Bentzen, L.1
Keiding, S.2
Nordsmark, M.3
Falborg, L.4
Hansen, S.B.5
Keller, J.6
-
35
-
-
20044390414
-
A kinetic model for dynamic [18F]-Fmiso PET data to analyse tumour hypoxia
-
PID: 15876662
-
Thorwarth D, Eschmann SM, Paulsen F, Alber M. A kinetic model for dynamic [18F]-Fmiso PET data to analyse tumour hypoxia. Phys Med Biol. 2005;50:2209–24.
-
(2005)
Phys Med Biol
, vol.50
, pp. 2209-2224
-
-
Thorwarth, D.1
Eschmann, S.M.2
Paulsen, F.3
Alber, M.4
|