Angiogenesis of glioma: Evaluation of ultrastructural characteristics of microvessels and tubular bodies (Weibel-Palade) in endothelial cells and immunohistochemical findings with VEGF and p53 protein

Medical Molecular Morphology

Volumn 38, Issue 1, 2005, Pages 36-42

  Miyagami, Mitsusuke ^a   Katayama, Yoichi ^b  

^a SURUGADAI NIHON UNIVERSITY HOSPITAL   (Japan)

^b NIHON UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Angiogenesis; Glioma; p53 protein; Tubular body (Weibel Palade body); VEGF

Indexed keywords

PROTEIN P53; VASCULOTROPIN; VASCULOTROPIN A;

ANGIOGENESIS; ASTROCYTOMA; ENDOTHELIUM CELL; GLIOBLASTOMA; GLIOMA; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MICROVASCULATURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; REVIEW; VASCULAR ENDOTHELIUM; WEIBEL PALADE BODY; BRAIN; BRAIN TUMOR; CAPILLARY; CHEMISTRY; HUMAN; METABOLISM; NEOVASCULARIZATION (PATHOLOGY); PATHOLOGY; ULTRASTRUCTURE; VASCULARIZATION;

BRAIN; BRAIN NEOPLASMS; CAPILLARIES; ENDOTHELIAL CELLS; GLIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; NEOVASCULARIZATION, PATHOLOGIC; TUMOR SUPPRESSOR PROTEIN P53; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WEIBEL-PALADE BODIES;

EID: 26944445860     PISSN: 18601480     EISSN: 18601499     Source Type: Journal    
DOI: 10.1007/s00795-004-0273-0     Document Type: Review

References (47)

1. Valtonen S, Timonen U, Toivanen P, Kalimo H, Kivipelto L, Heiskanen O, Unsgaad G, Kuurne T (1997) Interstitial chemotherapy with carmustine-loaded polymers for high grade gliomas: a randomized double-blind study. Neurosurgery 41:44-48
2. Nelson DF, Curran WJ Jr, Scott C, Nelson JS, Weinstein AS, Ahmad K, Constine LS, Murray K, Powlis WD, Mohiuddin M (1993) Hyperfractionated radiation therapy and bis-chlorethyl nitrosourea in the treatment of malignant glioma-possible advantage observed at 72.0 Gy in 1.2 Gy B.I.D. fractions: report of the Radiation Therapy Oncology Group Protocol 8302. Int J Radiat Oncol Biol Phys 25:193-207
3. Russel DS, Rubinstein LJ (1977) Pathology of tumours of the nervous system, 4th edn. Arnold, London, pp 235-236
4. Plate KH, Risau W (1995) Angiogenesis in malignant gliomas. Glia 15:339-347
5. Moriyasu N, Nakamura S, Miyagami M, Morisawa S, Igusa N (1971) The fine structure of capillary in the brain. J Clin Electron Microsc 4:771-776
6. Miygami M, Tsubokawa T (1989) Diagnostic efficacy of ultrastructural study in the tumor of central nervous system - ultrastructural properties of microvessels in human brain tumors. J Clin Electron Microsc 22:537-538
7. Miyagami M, Nakamura S (1997) Ultrastructure of microvessels and tumor cell processes on central neurocytoma. Brain Tumor Pathol 14:79-83
8. Miyagami M, Katayama Y, Kinukawa N, Sawada T (2002) An ultrastructural and immunohistochemical study of olfactory neuroepithelioma with rhabdomyoblasts. Med Electron Microsc 35:160-166
9. Long DM (1970) Capillary ultrastructure and the blood-brain barrier in human malignant brain tumours. J Neurosurg 32:127-144
10. Hirano A, Matsui T (1975) Vascular structures in brain tumours. Hum Pathol 6:611-622
11. Claley DW, Maxwell DS (1970) Development of the blood vessels and extracellular spaces during postnatal maturation of the rat cerebral cortex. J Comp Neurol 138:31-48
12. Weller RO, Foy M, Susan C (1977) The development and ultrastructure of the microvasculature in malignant gliomas. Neuropathol Appl Neurobiol 3:307-322
13. Weibel ER, Palade GE (1964) New cytoplasmic components in arterial endothelia. J Cell Biol 95:101-112
14. Matsuda H, Sugiura S (1970) Ultrastructure of "tubular body" in the endothelial cells of the ocular blood vessels. Invest Ophthalmol 9:919-925
15. Burri PH, Weibel ER (1968) Beeinflussung einer spezifischen cytoplsmatischen Organelle von Endothelzellen durch Adrenalin. Z Zellforsch Mikrosk Anat 88:426-440
16. Kagawa H, Fujimoto S (1987) Electron-microscopic and immunocytochemical analysis of Weibel-Palade bodies in the human umbilical vein during pregnancy. Cell Tissue Res 249:557-563
17. Wagner DD, Olmsted JB, Marcer VJ (1982) Immunolocalization of von Willebrand protein in Weibel-Palade bodies of human endothelial cells. J Cell Biol 95:355-360
18. Ewenstein BM, Warhol MJ, Handin RJ, Pober JS (1987) Composition of the von Willebrand factor storage organelle (Weibel-Palade body) isolated from cultured human umbilical vein endothelial cells. J Cell Biol 104:1423-1433
19. Dorovini-Zis K, Huynh K (1992) Ultrastructural localization of factor VIII-related antigen in cultured human brain microvessel endothelial cells. J Histochem Cytochem 40:689-696
20. Miyagami M, Tsubokawa T, Smith BH, Kornblith PL (1985) Immunocytochemical localization of factor VIII-related antigen and tubular bodies (Weibel-Palade bodies) in blood vessel of human gliomas. Neurol Med Chir 25:159-167
21. Miyagami M, Smith BH, Mckeever PE, Chronwall BM, Greenwood MA, Kornblith PL (1987) Immunocytochemical localization of factor VIII-related antigen in tumors of the human central nervous system. J Neuro-Oncol 4:269-285
22. Herrlinger H, Anzil AP, Blinzinger K, Kronski D (1974) Endothelial microtubular bodies in human brain capillaries and venules. J Anat 118:205-209
23. Hirano A (1974) Fine structural alterations of small vessels in the nervous system. In: Cervos-Navarro J (ed) Pathology of cerebral microcirculation. de Gruyter, Berlin, pp 203-217
24. Hirano A, Tomiyasu U, Zimmerman HM (1972) The fine structure of blood vessels in chromophobe adenoma. Acta Neuropathol (Berl) 22:200-207
25. Hirano A, Ghatak NR, Zimmerman HM (1973) The fine structure of ependymoblastoma. J Neuropathol Exp Neurol 32:144-152
26. Kawamura J, Kamijyo Y, Sunaga T, Nelson E (1974) Tubular bodies in vascular endothelium of a cerebellar neoplasm. Lab Invest 30:358-365
27. Kumar P, Kumar S, Marsden HB, Lynch PG, Earnshaw E (1980) Weibel-Palade bodies in endothelial cells as a marker for angiogenesis in brain tumors. Cancer Res 40:2010-2019
28. Ohsugi T, Hirano A (1977) Tubular bodies in endothelial cells in meningiomas. Neuropathol Appl Neurobiol 3:1-8
29. Hirano A, Ohsugi T, Matsumura H (1978) Pores and tubule-containing vacuoles in altered blood vessels of the central nervous system. In: Cervos-Navarro J (ed) Advances in neurology, vol 20. Raven Press, New York, pp 461-469
30. Miyagami M, Nakamura S (1996) Tubular bodies (Weibel-Palade bodies) in endothelial cells of glioblastomas and astrocytomas. Brain Tumor Pathol 13:107-114
31. Davison PM, Bensch K, Karasek MA (1980) Growth and morphology of rabbit marginal vessel endothelium in cell culture. J Cell Biol 85:187-198
32. Antonelli-Orlidge A, Saunders KB, Smith SR, D'Amore PA (1989) An activated form of transforming growth factor beta is produced by co-cultures of endothelial cells and pericytes. Proc Natl Acad Sci USA 86:4544-4548
33. Folkman J, Klagsbrun M (1987) Angiogenic factors. Science 235:442-447
34. Plate KH, Brier G, Farrell CL, Risau W (1992) Platelet-derived growth factor receptor-β is induced during tumor development and up-regulated during tumor progression in endothelial cells in human gliomas. Lab Invest 67:529-534
35. Weindel K, Moringlane JR, Marme D, Weich HA (1994) Detection and quantification of vascular endothelial growth factor/ vascular permeability factor in brain tumor tissue and cyst fluid: the key to angiogenesis? Neurosurgery 35:439-449
36. Connolly DT, Heuvelman DM, Nelson R, Olander JV, Eppley BL, Delfino JJ, Siegel NR, Leimgruber RM (1989) Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis. J Clin Invest 84:1470-1478
37. Plate KH, Breier G, Weich HA, Risau W (1992) Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo. Nature (Lond) 359:846-847
38. Shweiki D, Itin A, Neufeld G, Gitay-Goren H, Keshet E (1993) Patterns of expressions of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis. J Clin Invest 91:2235-2243
39. Matsuno A, Nagashima T (2004) Specific gene suppression using antisense strategy for growth suppression of glioma. Med Electron Microsc 37:158-161
40. Plate KH, Breier G, Weich HA, Mennel HD, Risau W (1994) Vascular endothelial growth factor and glioma angiogenesis: coordinate induction of VEGF receptors, distribution of VEGF protein and possible in vivo regulatory mechanisms. Int J Cancer 59:520-529
41. Maxwell M, Naber SP, Wolfe HJ, Hedley-Whyte ET, Galanopoulos T, Neville-Golden J, Antoniades HN (1991) Expression of angiogenic growth factor genes in primary human astrocytomas may contribute to their growth and progression. Cancer Res 51:1345-1351
42. Folkman J, Watson K, Ingber D, Hanahan D (1989) Induction of angiogenesis during the transition from hyperplasia to neoplasia. Nature (Lond) 339:58-61
43. Pepper MS, Ferrara N, Orci L, Montesano R (1991) Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells. Biochem Biophys Res Commun 181:902-906
44. Riordan JF, Vallee BL (1988) Human angiogenin, an organogenic protein. Br J Cancer 57:587-590
45. Pietsch T, Valter MM, Wolf HK, von Deimling A, Huang HJ, Cavenee WK, Wiestler OD (1997) Expression and distribution of vascular endothelial growth factor protein in human brain tumors. Acta Neuropathol 93:109-117
46. Miyagami M, Tazoe M, Nakamura S (1998) Expression of vascular endothelial growth factor and p53 protein in association with neovascularization in human malignant gliomas. Brain Tumor Pathol 15:95-100
47. Miyagami M, Katayama Y, Nakanura S (2000) Clinicopathological study of vascular endothelial growth factor (VEGF), p53, and proliferative potential in familial von Hippel-Lindau disease and sporadic hemangioblastomas. Brain Tumor Pathol 17:111-120