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Volumn 111, Issue 37, 2014, Pages E3870-E3879

TRPV6 calcium channel translocates to the plasma membrane via Orai1-mediated mechanism and controls cancer cell survival

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; CALCIUM CHANNEL; LIPOCORTIN 1; ORAI1 PROTEIN, HUMAN; PROTEIN S 100; S100A11 PROTEIN, HUMAN; TRPV6 PROTEIN, HUMAN; TUMOR PROTEIN; VANILLOID RECEPTOR;

EID: 84907235984     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1413409111     Document Type: Article
Times cited : (97)

References (56)
  • 1
  • 2
    • 78149377824 scopus 로고    scopus 로고
    • Prostate cancer around theworld. An overview
    • Schröder FH (2010) Prostate cancer around theworld. An overview. Urol Oncol 28(6): 663-667.
    • (2010) Urol Oncol , vol.28 , Issue.6 , pp. 663-667
    • Schröder, F.H.1
  • 3
    • 0036789162 scopus 로고    scopus 로고
    • Apoptosis resistance of neuroendocrine phenotypes in prostatic adenocarcinoma
    • Fixemer T, Remberger K, Bonkhoff H (2002) Apoptosis resistance of neuroendocrine phenotypes in prostatic adenocarcinoma. Prostate 53(2): 118-123.
    • (2002) Prostate , vol.53 , Issue.2 , pp. 118-123
    • Fixemer, T.1    Remberger, K.2    Bonkhoff, H.3
  • 4
    • 0029077281 scopus 로고
    • Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo
    • Raffo AJ, et al. (1995) Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo. Cancer Res 55(19): 4438-4445.
    • (1995) Cancer Res , vol.55 , Issue.19 , pp. 4438-4445
    • Raffo, A.J.1
  • 6
    • 0035380605 scopus 로고    scopus 로고
    • Expression of CaT-like, a novel calcium-selective channel, correlates with the malignancy of prostate cancer
    • Wissenbach U, et al. (2001) Expression of CaT-like, a novel calcium-selective channel, correlates with the malignancy of prostate cancer. J Biol Chem 276(22): 19461-19468.
    • (2001) J Biol Chem , vol.276 , Issue.22 , pp. 19461-19468
    • Wissenbach, U.1
  • 7
    • 0034815351 scopus 로고    scopus 로고
    • CaT1 expression correlates with tumor grade in prostate cancer
    • Peng JB, et al. (2001) CaT1 expression correlates with tumor grade in prostate cancer. Biochem Biophys Res Commun 282(3): 729-734.
    • (2001) Biochem Biophys Res Commun , vol.282 , Issue.3 , pp. 729-734
    • Peng, J.B.1
  • 8
    • 0345304866 scopus 로고    scopus 로고
    • Expression of the Ca2+-selective cation channel TRPV6 in human prostate cancer: A novel prognostic marker for tumor progression
    • Fixemer T, Wissenbach U, Flockerzi V, Bonkhoff H (2003) Expression of the Ca2+-selective cation channel TRPV6 in human prostate cancer: A novel prognostic marker for tumor progression. Oncogene 22(49): 7858-7861.
    • (2003) Oncogene , vol.22 , Issue.49 , pp. 7858-7861
    • Fixemer, T.1    Wissenbach, U.2    Flockerzi, V.3    Bonkhoff, H.4
  • 9
    • 77949327468 scopus 로고    scopus 로고
    • Ion channels and the hallmarks of cancer
    • Prevarskaya N, Skryma R, Shuba Y (2010) Ion channels and the hallmarks of cancer. Trends Mol Med 16(3): 107-121.
    • (2010) Trends Mol Med , vol.16 , Issue.3 , pp. 107-121
    • Prevarskaya, N.1    Skryma, R.2    Shuba, Y.3
  • 10
    • 79960759956 scopus 로고    scopus 로고
    • Calcium in tumour metastasis: New roles for known actors
    • Prevarskaya N, Skryma R, Shuba Y (2011) Calcium in tumour metastasis: New roles for known actors. Nat Rev Cancer 11(8): 609-618.
    • (2011) Nat Rev Cancer , vol.11 , Issue.8 , pp. 609-618
    • Prevarskaya, N.1    Skryma, R.2    Shuba, Y.3
  • 11
    • 0035861551 scopus 로고    scopus 로고
    • Ca2+ pools and cell growth. Evidence for sarcoendoplasmic Ca2+-ATPases 2B involvement in human prostate cancer cell growth control
    • Legrand G, et al. (2001) Ca2+ pools and cell growth. Evidence for sarcoendoplasmic Ca2+-ATPases 2B involvement in human prostate cancer cell growth control. J Biol Chem 276(50): 47608-47614.
    • (2001) J Biol Chem , vol.276 , Issue.50 , pp. 47608-47614
    • Legrand, G.1
  • 12
    • 33644515955 scopus 로고    scopus 로고
    • Differential role of transient receptor potential channels in Ca2+ entry and proliferation of prostate cancer epithelial cells
    • Thebault S, et al. (2006) Differential role of transient receptor potential channels in Ca2+ entry and proliferation of prostate cancer epithelial cells. Cancer Res 66(4): 2038-2047.
    • (2006) Cancer Res , vol.66 , Issue.4 , pp. 2038-2047
    • Thebault, S.1
  • 13
    • 1542329629 scopus 로고    scopus 로고
    • Ca2+ homeostasis and apoptotic resistance of neuroendocrine-differentiated prostate cancer cells
    • Vanoverberghe K, et al. (2004) Ca2+ homeostasis and apoptotic resistance of neuroendocrine-differentiated prostate cancer cells. Cell Death Differ 11(3): 321-330.
    • (2004) Cell Death Differ , vol.11 , Issue.3 , pp. 321-330
    • Vanoverberghe, K.1
  • 14
    • 0033846088 scopus 로고    scopus 로고
    • Store depletion and store-operated Ca2+ current in human prostate cancer LNCaP cells: Involvement in apoptosis
    • Skryma R, et al. (2000) Store depletion and store-operated Ca2+ current in human prostate cancer LNCaP cells: Involvement in apoptosis. J Physiol 527(Pt 1): 71-83.
    • (2000) J Physiol , vol.527 , pp. 71-83
    • Skryma, R.1
  • 15
    • 0037674385 scopus 로고    scopus 로고
    • Storeoperated Ca2+ current in prostate cancer epithelial cells. Role of endogenous Ca2+ transporter type 1
    • Vanden Abeele F, Roudbaraki M, Shuba Y, Skryma R, Prevarskaya N (2003) Storeoperated Ca2+ current in prostate cancer epithelial cells. Role of endogenous Ca2+ transporter type 1. J Biol Chem 278(17): 15381-15389.
    • (2003) J Biol Chem , vol.278 , Issue.17 , pp. 15381-15389
    • Vanden Abeele, F.1    Roudbaraki, M.2    Shuba, Y.3    Skryma, R.4    Prevarskaya, N.5
  • 16
    • 0036491629 scopus 로고    scopus 로고
    • Bcl-2-dependent modulation of Ca(2+) homeostasis and store-operated channels in prostate cancer cells
    • Vanden Abeele F, et al. (2002) Bcl-2-dependent modulation of Ca(2+) homeostasis and store-operated channels in prostate cancer cells. Cancer Cell 1(2): 169-179.
    • (2002) Cancer Cell , vol.1 , Issue.2 , pp. 169-179
    • Vanden Abeele, F.1
  • 17
    • 79959807784 scopus 로고    scopus 로고
    • The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway
    • Tauzin S, et al. (2011) The naturally processed CD95L elicits a c-yes/calcium/PI3K-driven cell migration pathway. PLoS Biol 9(6): e1001090.
    • (2011) PLoS Biol , vol.9 , Issue.6 , pp. e1001090
    • Tauzin, S.1
  • 18
    • 82755186493 scopus 로고    scopus 로고
    • CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation
    • Khadra N, et al. (2011) CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation. Proc Natl Acad Sci USA 108(47): 19072-19077.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.47 , pp. 19072-19077
    • Khadra, N.1
  • 19
    • 0036903548 scopus 로고    scopus 로고
    • Calcium-selective ion channel, CaT1, is apically localized in gastrointestinal tract epithelia and is aberrantly expressed in human malignancies
    • Zhuang L, et al. (2002) Calcium-selective ion channel, CaT1, is apically localized in gastrointestinal tract epithelia and is aberrantly expressed in human malignancies. Lab Invest 82(12): 1755-1764.
    • (2002) Lab Invest , vol.82 , Issue.12 , pp. 1755-1764
    • Zhuang, L.1
  • 20
    • 79958284668 scopus 로고    scopus 로고
    • Orai1 contributes to the establishment of an apoptosisresistant phenotype in prostate cancer cells
    • Flourakis M, et al. (2010) Orai1 contributes to the establishment of an apoptosisresistant phenotype in prostate cancer cells. Cell Death Dis 1: e75.
    • (2010) Cell Death Dis , vol.1 , pp. e75
    • Flourakis, M.1
  • 21
    • 3142717480 scopus 로고    scopus 로고
    • Two types of store-operated Ca2+ channels with different activation modes and molecular origin in LNCaP human prostate cancer epithelial cells
    • Vanden Abeele F, et al. (2004) Two types of store-operated Ca2+ channels with different activation modes and molecular origin in LNCaP human prostate cancer epithelial cells. J Biol Chem 279(29): 30326-30337.
    • (2004) J Biol Chem , vol.279 , Issue.29 , pp. 30326-30337
    • Vanden Abeele, F.1
  • 22
    • 34447097610 scopus 로고    scopus 로고
    • STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels
    • Yuan JP, Zeng W, Huang GN, Worley PF, Muallem S (2007) STIM1 heteromultimerizes TRPC channels to determine their function as store-operated channels. Nat Cell Biol 9(6): 636-645.
    • (2007) Nat Cell Biol , vol.9 , Issue.6 , pp. 636-645
    • Yuan, J.P.1    Zeng, W.2    Huang, G.N.3    Worley, P.F.4    Muallem, S.5
  • 23
    • 84870296401 scopus 로고    scopus 로고
    • Inhibition of the human epithelial calcium channel TRPV6 by 2-aminoethoxydiphenyl borate (2-APB)
    • Kovacs G, et al. (2012) Inhibition of the human epithelial calcium channel TRPV6 by 2-aminoethoxydiphenyl borate (2-APB). Cell Calcium 52(6): 468-480.
    • (2012) Cell Calcium , vol.52 , Issue.6 , pp. 468-480
    • Kovacs, G.1
  • 24
    • 0034687556 scopus 로고    scopus 로고
    • Human calcium transport protein CaT1
    • Peng JB, et al. (2000) Human calcium transport protein CaT1. Biochem Biophys Res Commun 278(2): 326-332.
    • (2000) Biochem Biophys Res Commun , vol.278 , Issue.2 , pp. 326-332
    • Peng, J.B.1
  • 25
    • 4444248382 scopus 로고    scopus 로고
    • TRPV6 and prostate cancer: Cancer growth beyond the prostate correlates with increased TRPV6 Ca2+ channel expression
    • Wissenbach U, et al. (2004) TRPV6 and prostate cancer: Cancer growth beyond the prostate correlates with increased TRPV6 Ca2+ channel expression. Biochem Biophys Res Commun 322(4): 1359-1363.
    • (2004) Biochem Biophys Res Commun , vol.322 , Issue.4 , pp. 1359-1363
    • Wissenbach, U.1
  • 26
    • 84858175916 scopus 로고    scopus 로고
    • The role of the TRPV6 channel in cancer
    • Lehen'kyi V, Raphaël M, Prevarskaya N (2012) The role of the TRPV6 channel in cancer. J Physiol 590(Pt 6): 1369-1376.
    • (2012) J Physiol , vol.590 , pp. 1369-1376
    • Lehen'kyi, V.1    Raphaël, M.2    Prevarskaya, N.3
  • 27
    • 4344644067 scopus 로고    scopus 로고
    • Ca2+ dependence of the Ca2+-selective TRPV6 channel
    • Bödding M, Flockerzi V (2004) Ca2+ dependence of the Ca2+-selective TRPV6 channel. J Biol Chem 279(35): 36546-36552.
    • (2004) J Biol Chem , vol.279 , Issue.35 , pp. 36546-36552
    • Bödding, M.1    Flockerzi, V.2
  • 28
    • 0037178836 scopus 로고    scopus 로고
    • Store depletion-activated CaT1 currents in rat basophilic leukemia mast cells are inhibited by 2-aminoethoxydiphenyl borate. Evidence for a regulatory component that controls activation of both CaT1 and CRAC (Ca(2+) release-activated Ca(2+) channel) channels
    • Schindl R, Kahr H, Graz I, Groschner K, Romanin C (2002) Store depletion-activated CaT1 currents in rat basophilic leukemia mast cells are inhibited by 2-aminoethoxydiphenyl borate. Evidence for a regulatory component that controls activation of both CaT1 and CRAC (Ca(2+) release-activated Ca(2+) channel) channels. J Biol Chem 277(30): 26950-26958.
    • (2002) J Biol Chem , vol.277 , Issue.30 , pp. 26950-26958
    • Schindl, R.1    Kahr, H.2    Graz, I.3    Groschner, K.4    Romanin, C.5
  • 29
    • 26444608501 scopus 로고    scopus 로고
    • TRPV5 and TRPV6 in Ca(2+) (re)absorption: Regulating Ca(2+) entry at the gate
    • Nijenhuis T, Hoenderop JG, Bindels RJ (2005) TRPV5 and TRPV6 in Ca(2+) (re)absorption: Regulating Ca(2+) entry at the gate. Pflugers Arch 451(1): 181-192.
    • (2005) Pflugers Arch , vol.451 , Issue.1 , pp. 181-192
    • Nijenhuis, T.1    Hoenderop, J.G.2    Bindels, R.J.3
  • 30
    • 84867412996 scopus 로고    scopus 로고
    • Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx
    • Schindl R, et al. (2012) Canonical transient receptor potential (TRPC) 1 acts as a negative regulator for vanilloid TRPV6-mediated Ca2+ influx. J Biol Chem 287(42): 35612-35620.
    • (2012) J Biol Chem , vol.287 , Issue.42 , pp. 35612-35620
    • Schindl, R.1
  • 32
    • 33645222317 scopus 로고    scopus 로고
    • Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane
    • van de Graaf SF, Chang Q, Mensenkamp AR, Hoenderop JG, Bindels RJ (2006) Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane. Mol Cell Biol 26(1): 303-312.
    • (2006) Mol Cell Biol , vol.26 , Issue.1 , pp. 303-312
    • Van De-Graaf, S.F.1    Chang, Q.2    Mensenkamp, A.R.3    Hoenderop, J.G.4    Bindels, R.J.5
  • 33
    • 0037388490 scopus 로고    scopus 로고
    • Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex
    • van de Graaf SF, et al. (2003) Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex. EMBO J 22(7): 1478-1487.
    • (2003) EMBO J , vol.22 , Issue.7 , pp. 1478-1487
    • Van De-Graaf, S.F.1
  • 34
    • 54149087686 scopus 로고    scopus 로고
    • The beta-glucuronidase klotho exclusively activates the epithelial Ca2+ channels TRPV5 and TRPV6
    • Lu P, Boros S, Chang Q, Bindels RJ, Hoenderop JG (2008) The beta-glucuronidase klotho exclusively activates the epithelial Ca2+ channels TRPV5 and TRPV6. Nephrol Dial Transplant 23(11): 3397-3402.
    • (2008) Nephrol Dial Transplant , vol.23 , Issue.11 , pp. 3397-3402
    • Lu, P.1    Boros, S.2    Chang, Q.3    Bindels, R.J.4    Hoenderop, J.G.5
  • 36
    • 36148992621 scopus 로고    scopus 로고
    • TRPV6 channel controls prostate cancer cell proliferation via Ca(2+)/NFAT-dependent pathways
    • Lehen'kyi V, Flourakis M, Skryma R, Prevarskaya N (2007) TRPV6 channel controls prostate cancer cell proliferation via Ca(2+)/NFAT-dependent pathways. Oncogene 26(52): 7380-7385.
    • (2007) Oncogene , vol.26 , Issue.52 , pp. 7380-7385
    • Lehen'kyi, V.1    Flourakis, M.2    Skryma, R.3    Prevarskaya, N.4
  • 37
    • 1242276313 scopus 로고    scopus 로고
    • Alteration in temporal kinetics of Ca2+ signaling and control of growth and proliferation
    • Lipskaia L, Lompré AM (2004) Alteration in temporal kinetics of Ca2+ signaling and control of growth and proliferation. Biol Cell 96(1): 55-68.
    • (2004) Biol Cell , vol.96 , Issue.1 , pp. 55-68
    • Lipskaia, L.1    Lompré, A.M.2
  • 38
    • 15844416253 scopus 로고    scopus 로고
    • Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity
    • Loh C, et al. (1996) Calcineurin binds the transcription factor NFAT1 and reversibly regulates its activity. J Biol Chem 271(18): 10884-10891.
    • (1996) J Biol Chem , vol.271 , Issue.18 , pp. 10884-10891
    • Loh, C.1
  • 39
    • 0036864625 scopus 로고    scopus 로고
    • NFATc2-mediated repression of cyclin-dependent kinase 4 expression
    • Baksh S, et al. (2002) NFATc2-mediated repression of cyclin-dependent kinase 4 expression. Mol Cell 10(5): 1071-1081.
    • (2002) Mol Cell , vol.10 , Issue.5 , pp. 1071-1081
    • Baksh, S.1
  • 40
    • 0036884463 scopus 로고    scopus 로고
    • NFATC2 transcription factor regulates cell cycle progression during lymphocyte activation: Evidence of its involvement in the control of cyclin gene expression
    • Caetano MS, et al. (2002) NFATC2 transcription factor regulates cell cycle progression during lymphocyte activation: Evidence of its involvement in the control of cyclin gene expression. FASEB J 16(14): 1940-1942.
    • (2002) FASEB J , vol.16 , Issue.14 , pp. 1940-1942
    • Caetano, M.S.1
  • 42
    • 0037163111 scopus 로고    scopus 로고
    • Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3
    • Nilius B, et al. (2002) Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3. J Biol Chem 277(34): 30852-30858.
    • (2002) J Biol Chem , vol.277 , Issue.34 , pp. 30852-30858
    • Nilius, B.1
  • 43
    • 0037292330 scopus 로고    scopus 로고
    • The carboxyl terminus of the epithelial Ca(2+) channel ECaC1 is involved in Ca(2+)-dependent inactivation
    • Nilius B, et al. (2003) The carboxyl terminus of the epithelial Ca(2+) channel ECaC1 is involved in Ca(2+)-dependent inactivation. Pflugers Arch 445(5): 584-588.
    • (2003) Pflugers Arch , vol.445 , Issue.5 , pp. 584-588
    • Nilius, B.1
  • 44
    • 82455219496 scopus 로고    scopus 로고
    • Ion channnels and transporters in cancer. 5. Ion channels in control of cancer and cell apoptosis
    • Lehen'kyi V, Shapovalov G, Skryma R, Prevarskaya N (2011) Ion channnels and transporters in cancer. 5. Ion channels in control of cancer and cell apoptosis. Am J Physiol Cell Physiol 301(6): C1281-C1289.
    • (2011) Am J Physiol Cell Physiol , vol.301 , Issue.6 , pp. C1281-C1289
    • Lehen'kyi, V.1    Shapovalov, G.2    Skryma, R.3    Prevarskaya, N.4
  • 45
    • 76249107718 scopus 로고    scopus 로고
    • Role of cationic channel TRPV2 in promoting prostate cancer migration and progression to androgen resistance
    • Monet M, et al. (2010) Role of cationic channel TRPV2 in promoting prostate cancer migration and progression to androgen resistance. Cancer Res 70(3): 1225-1235.
    • (2010) Cancer Res , vol.70 , Issue.3 , pp. 1225-1235
    • Monet, M.1
  • 46
    • 4444272272 scopus 로고    scopus 로고
    • Ca2+ homeostasis in apoptotic resistance of prostate cancer cells
    • Prevarskaya N, Skryma R, Shuba Y (2004) Ca2+ homeostasis in apoptotic resistance of prostate cancer cells. Biochem Biophys Res Commun 322(4): 1326-1335.
    • (2004) Biochem Biophys Res Commun , vol.322 , Issue.4 , pp. 1326-1335
    • Prevarskaya, N.1    Skryma, R.2    Shuba, Y.3
  • 47
    • 0035060354 scopus 로고    scopus 로고
    • Is cisplatin-induced cell death always produced by apoptosis?
    • Gonzalez VM, Fuertes MA, Alonso C, Perez JM (2001) Is cisplatin-induced cell death always produced by apoptosis? Mol Pharmacol 59(4): 657-663.
    • (2001) Mol Pharmacol , vol.59 , Issue.4 , pp. 657-663
    • Gonzalez, V.M.1    Fuertes, M.A.2    Alonso, C.3    Perez, J.M.4
  • 48
    • 33645124763 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism
    • Di Sano F, et al. (2006) Endoplasmic reticulum stress induces apoptosis by an apoptosome-dependent but caspase 12-independent mechanism. J Biol Chem 281(5): 2693-2700.
    • (2006) J Biol Chem , vol.281 , Issue.5 , pp. 2693-2700
    • Di Sano, F.1
  • 49
    • 29244454269 scopus 로고    scopus 로고
    • Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis
    • Nawrocki ST, et al. (2005) Bortezomib sensitizes pancreatic cancer cells to endoplasmic reticulum stress-mediated apoptosis. Cancer Res 65(24): 11658-11666.
    • (2005) Cancer Res , vol.65 , Issue.24 , pp. 11658-11666
    • Nawrocki, S.T.1
  • 50
    • 84858726313 scopus 로고    scopus 로고
    • Regulation of cell death and autophagy by IKK and NF-κB: Critical mechanisms in immune function and cancer
    • Baldwin AS (2012) Regulation of cell death and autophagy by IKK and NF-κB: Critical mechanisms in immune function and cancer. Immunol Rev 246(1): 327-345.
    • (2012) Immunol Rev , vol.246 , Issue.1 , pp. 327-345
    • Baldwin, A.S.1
  • 51
    • 33846168720 scopus 로고    scopus 로고
    • The nuclear factor-kappaB (NF-kappaB): From a versatile transcription factor to a ubiquitous therapeutic target
    • Yates LL, Górecki DC (2006) The nuclear factor-kappaB (NF-kappaB): From a versatile transcription factor to a ubiquitous therapeutic target. Acta Biochim Pol 53(4): 651-662.
    • (2006) Acta Biochim Pol , vol.53 , Issue.4 , pp. 651-662
    • Yates, L.L.1    Górecki, D.C.2
  • 52
    • 78349311201 scopus 로고    scopus 로고
    • Modeling oscillatory control in NF-κB, p53 and Wnt signaling
    • Mengel B, et al. (2010) Modeling oscillatory control in NF-κB, p53 and Wnt signaling. Curr Opin Genet Dev 20(6): 656-664.
    • (2010) Curr Opin Genet Dev , vol.20 , Issue.6 , pp. 656-664
    • Mengel, B.1
  • 53
    • 34548399498 scopus 로고    scopus 로고
    • Transglutaminase-mediated activation of nuclear transcription factor-kappaB in cancer cells: A new therapeutic opportunity
    • Verma A, Mehta K (2007) Transglutaminase-mediated activation of nuclear transcription factor-kappaB in cancer cells: A new therapeutic opportunity. Curr Cancer Drug Targets 7(6): 559-565.
    • (2007) Curr Cancer Drug Targets , vol.7 , Issue.6 , pp. 559-565
    • Verma, A.1    Mehta, K.2
  • 54
    • 33845656359 scopus 로고    scopus 로고
    • Passive calcium leak via translocon is a first step for iPLA2-pathway regulated store operated channels activation
    • Flourakis M, et al. (2006) Passive calcium leak via translocon is a first step for iPLA2-pathway regulated store operated channels activation. FASEB J 20(8): 1215-1217.
    • (2006) FASEB J , vol.20 , Issue.8 , pp. 1215-1217
    • Flourakis, M.1
  • 55
    • 34250865694 scopus 로고    scopus 로고
    • Tumor alphavbeta3 integrin is a therapeutic target for breast cancer bone metastases
    • Zhao Y, et al. (2007) Tumor alphavbeta3 integrin is a therapeutic target for breast cancer bone metastases. Cancer Res 67(12): 5821-5830.
    • (2007) Cancer Res , vol.67 , Issue.12 , pp. 5821-5830
    • Zhao, Y.1
  • 56
    • 43149090543 scopus 로고    scopus 로고
    • Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation
    • Muik M, et al. (2008) Dynamic coupling of the putative coiled-coil domain of ORAI1 with STIM1 mediates ORAI1 channel activation. J Biol Chem 283(12): 8014-8022.
    • (2008) J Biol Chem , vol.283 , Issue.12 , pp. 8014-8022
    • Muik, M.1


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