Association of urinary RBP4 with insulin resistance, inflammation, and microalbuminuria

European Journal of Endocrinology

Volumn 171, Issue 4, 2014, Pages 443-449

  Park, Se Eun ^a   Lee, Nam Seok ^b   Park, Ji Woo ^b   Rhee, Eun Jung ^a   Lee, Won Young ^a   Oh, Ki Won ^a   Park, Sung Woo ^a   Park, Cheol Young ^a   Youn, Byung Soo ^b,c  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Songdo Technopark ^*  (South Korea)

^c Wonkwang University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; C REACTIVE PROTEIN; CHOLESTEROL; CREATININE; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PREALBUMIN; RETINOL BINDING PROTEIN 4; TRIACYLGLYCEROL; BIOLOGICAL MARKER; INSULIN; PLASMA RETINOL BINDING PROTEIN; RBP4 PROTEIN, HUMAN;

AGE; ALBUMIN TO CREATININE RATIO; AREA UNDER THE CURVE; ARTERIAL STIFFNESS; ARTICLE; BLOOD PRESSURE MEASUREMENT; BODY MASS; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; CORRELATION ANALYSIS; CREATININE BLOOD LEVEL; DIASTOLIC BLOOD PRESSURE; DISEASE ASSOCIATION; DISEASE SEVERITY; ESTIMATED GLOMERULAR FILTRATION RATE; FEMALE; GLOMERULUS FILTRATION RATE; GLUCOSE BLOOD LEVEL; GLUCOSE TOLERANCE; HEMOGLOBIN BLOOD LEVEL; HOMEOSTASIS MODEL ASSESSMENT; HUMAN; IMPAIRED GLUCOSE TOLERANCE; INFLAMMATION; INSULIN RESISTANCE; INSULIN SENSITIVITY; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MEASUREMENT; MICROALBUMINURIA; NON INSULIN DEPENDENT DIABETES MELLITUS; PROTEIN BLOOD LEVEL; PROTEIN URINE LEVEL; PULSE WAVE; RECEIVER OPERATING CHARACTERISTIC; RENAL SYSTEM PARAMETERS; SYSTOLIC BLOOD PRESSURE; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE; ADULT; AGED; ALBUMINURIA; BLOOD; CARDIOVASCULAR DISEASE; METABOLISM; MIDDLE AGED; PREDICTIVE VALUE; RISK FACTOR; URINE;

ADULT; AGED; ALBUMINURIA; AREA UNDER CURVE; BIOLOGICAL MARKERS; BLOOD GLUCOSE; C-REACTIVE PROTEIN; CARDIOVASCULAR DISEASES; FEMALE; HUMANS; INFLAMMATION; INSULIN; INSULIN RESISTANCE; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; RETINOL-BINDING PROTEINS, PLASMA; RISK FACTORS; ROC CURVE; VASCULAR STIFFNESS;

EID: 84907224314     PISSN: 08044643     EISSN: 1479683X     Source Type: Journal    
DOI: 10.1530/EJE-14-0247     Document Type: Article

References (29)

1. Reaven GM. Insulin resistance, the insulin resistance syndrome, and cardiovascular disease. Panminerva Medica 2005 47 201-210.
2. Yang Q, Graham TE, Mody N, Preitner F, Peroni OD, Zabolotny JM, Kotani K, Quadro L & Kahn BB. Serum retinol binding protein 4 contributes to insulin resistance in obesity and type 2 diabetes. Nature 2005 436 356-362. (doi:10.1038/nature03711)
3. Muoio DM & Newgard CB. Metabolism: a is for adipokine. Nature 2005 436 337-338. (doi:10.1038/436337a)
4. Graham TE, Yang Q, Bluher M, Hammarstedt A, Ciaraldi TP, Henry RR, Wason CJ, Oberbach A, Jansson PA, Smith U et al. Retinol-binding protein 4 and insulin resistance in lean, obese, and diabetic subjects. New England Journal of Medicine 2006 354 2552-2563. (doi:10.1056/ NEJMoa054862)
5. Stehouwer CD, Gall MA, Twisk JW, Knudsen E, Emeis JJ & Parving HH. Increased urinary albumin excretion, endothelial dysfunction, and chronic low-grade inflammation in type 2 diabetes: progressive, interrelated, and independently associated with risk of death. Diabetes 2002 51 1157-1165. (doi:10.2337/diabetes.51.4.1157)
6. Mykkanen L, Zaccaro DJ, O'Leary DH, Howard G, Robbins DC & Haffner SM. Microalbuminuria and carotid artery intima-media thickness in nondiabetic and NIDDM subjects. The Insulin Resistance Atherosclerosis Study (IRAS). Stroke 1997 28 1710-1716. (doi:10.1161/ 01.STR.28.9.1710)
7. Parvanova AI, Trevisan R, Iliev IP, Dimitrov BD, Vedovato M, Tiengo A, Remuzzi G & Ruggenenti P. Insulin resistance and microalbuminuria: a cross-sectional, case-control study of 158 patients with type 2 diabetes and different degrees of urinary albumin excretion. Diabetes 2006 55 1456-1462. (doi:10.2337/db05-1484)
8. Raila J, Henze A, Spranger J, Mohlig M, Pfeiffer AF & Schweigert FJ. Microalbuminuria is a major determinant of elevated plasma retinolbinding protein 4 in type 2 diabetic patients. Kidney International 2007 72 505-511. (doi:10.1038/sj.ki.5002372)
9. XuM, Li XY, Wang JG,Wang XJ, Huang Y, Cheng Q, Huang HE, Li R, Xiang J, Tan JR et al. Retinol-binding protein 4 is associatedwith impaired glucose regulation and microalbuminuria in a Chinese population. Diabetologia 2009 52 1511-1519. (doi:10.1007/s00125-009-1386-8)
10. Graham TE, Wason CJ, Bluher M & Kahn BB. Shortcomings in methodology complicate measurements of serum retinol binding protein (RBP4) in insulin-resistant human subjects. Diabetologia 2007 50 814-823. (doi:10.1007/s00125-006-0557-0)
11. Cabre A, Lazaro I, Girona J, Manzanares J,Marimon F, Plana N, HerasM & Masana L. Retinol-binding protein 4 as a plasma biomarker of renal dysfunction and cardiovascular disease in type 2 diabetes. Journal of Internal Medicine 2007 262 496-503. (doi:10.1111/j.1365-2796.2007.01849.x)
12. Axelsson J, O'Byrne SM, Blaner WS, Carrero JJ, Bruchfeld A, Heimburger O, Barany P, Lindholm B & Stenvinkel P. Serum retinolbinding protein concentration and its association with components of the uremic metabolic syndrome in nondiabetic patients with chronic kidney disease stage 5. American Journal of Nephrology 2009 29 447-453. (doi:10.1159/000176534)
13. Henze A, Frey SK, Raila J, Tepel M, Scholze A, Pfeiffer AF,Weickert MO, Spranger J & Schweigert FJ. Evidence that kidney function but not type 2 diabetes determines retinol-binding protein 4 serum levels. Diabetes 2008 57 3323-3326. (doi:10.2337/db08-0866)
14. Won JC, Park CY, Park HS, Kim JH, Choi ES, Rhee EJ, Lee WY, Oh KW, Kim SW & Park SW. 1,5-Anhydroglucitol reflects postprandial hyperglycemia and a decreased insulinogenic index, even in subjects with prediabetes and well-controlled type 2 diabetes. Diabetes Research and Clinical Practice 2009 84 51-57. (doi:10.1016/j.diabres.2009.01.002)
15. Diagnosis and classification of diabetes mellitus. Diabetes Care 2005 28 S37-S42. (doi:10.2337/diacare.28.suppl-1.S37)
16. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF & Turner RC. Homeostasis model assessment: insulin resistance and b-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985 28 412-419. (doi:10.1007/BF00280883)
17. Kuan Y, Hossain M, Surman J, El Nahas AM & Haylor J. GFR prediction using the MDRD and Cockcroft and Gault equations in patients with end-stage renal disease. Nephrology, Dialysis, Transplantation 2005 20 2394-2401. (doi:10.1093/ndt/gfi076)
18. Zanotti G & Berni R. Plasma retinol-binding protein: structure and interactions with retinol, retinoids, and transthyretin. Vitamins and Hormones 2004 69 271-295. (doi:10.1016/S0083-6729(04)69010-8)
19. Abahusain MA, Wright J, Dickerson JW & de Vol EB. Retinol, a-tocopherol and carotenoids in diabetes. European Journal of Clinical Nutrition 1999 53 630-635. (doi:10.1038/sj.ejcn.1600825)
20. Yao-Borengasser A, Varma V, Bodles AM, Rasouli N, Phanavanh B, Lee MJ, Starks T, Kern LM, Spencer HJ III, Rashidi AA et al. Retinol binding protein 4 expression in humans: relationship to insulin resistance, inflammation, and response to pioglitazone. Journal of Clinical Endocrinology and Metabolism 2007 92 2590-2597. (doi:10.1210/jc.2006-0816)
21. Perseghin G, Petersen K & Shulman GI. Cellular mechanism of insulin resistance: potential links with inflammation. International Journal of Obesity and Related Metabolic Disorders 2003 27 S6-11. (doi:10.1038/ sj.ijo.0802491)
22. Hong CY & Chia KS. Markers of diabetic nephropathy. Journal of Diabetes and its Complications 1998 12 43-60. (doi:10.1016/S1056-8727(97)00045-7)
23. Birn H & Christensen EI. Renal albumin absorption in physiology and pathology. Kidney International 2006 69 440-449. (doi:10.1038/ sj.ki.5000141)
24. Tesch GH. Macrophages and diabetic nephropathy. Seminars in Nephrology 2010 30 290-301. (doi:10.1016/j.semnephrol.2010.03.007)
25. Libby P. Inflammation and cardiovascular disease mechanisms. American Journal of Clinical Nutrition 2006 83 456S-460S.
26. Sun Q, Kiernan UA, Shi L, Phillips DA, Kahn BB, Hu FB, Manson JE, Albert CM & Rexrode KM. Plasma retinol-binding protein 4 (RBP4) levels and risk of coronary heart disease: a prospective analysis among women in the nurses' health study. Circulation 2013 127 1938-1947. (doi:10.1161/CIRCULATIONAHA.113.002073)
27. Zieman SJ, Melenovsky V & Kass DA. Mechanisms, pathophysiology, and therapy of arterial stiffness. Arteriosclerosis Thrombosis and Vascular Biology 2005 25 932-943.
28. Smith A, Karalliedde J, De Angelis L, Goldsmith D & Viberti G. Aortic pulse wave velocity and albuminuria in patients with type 2 diabetes. Journal of the American Society of Nephrology 2005 16 1069-1075.
29. Stehouwer CD, Nauta JJ, Zeldenrust GC, Hackeng WH, Donker AJ & den Ottolander GJ. Urinary albumin excretion, cardiovascular disease, and endothelial dysfunction in non-insulin-dependent diabetes mellitus. Lancet 1992 340 319-323.