-
1
-
-
84877581057
-
Emerging low-density lipoprotein therapies: Microsomal triglyceride transfer protein inhibitors
-
Goldberg AC. Emerging low-density lipoprotein therapies: microsomal triglyceride transfer protein inhibitors. J Clin Lipidol. 2013; 7(suppl 3):S16-20.
-
(2013)
J Clin Lipidol
, vol.7
, pp. S16-S20
-
-
Goldberg, A.C.1
-
2
-
-
84874956296
-
Management of familial hypercholesterolemia: A review of the recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia
-
Robinson JG. Management of familial hypercholesterolemia: a review of the recommendations from the National Lipid Association Expert Panel on Familial Hypercholesterolemia. J Manag Care Pharm. 2013; 19:139-49.
-
(2013)
J Manag Care Pharm
, vol.19
, pp. 139-149
-
-
Robinson, J.G.1
-
3
-
-
84864772507
-
Homozygous familial hypercholesterolemia: Current perspectives on diagnosis and treatment
-
Raal FJ, Santos RD. Homozygous familial hypercholesterolemia: current perspectives on diagnosis and treatment. Atherosclerosis. 2012; 223:262-8.
-
(2012)
Atherosclerosis
, vol.223
, pp. 262-268
-
-
Raal, F.J.1
Santos, R.D.2
-
4
-
-
84880608435
-
Recent advances in the treatment of homozygous familial hypercholesterolaemia
-
Marais AD, Blom DJ. Recent advances in the treatment of homozygous familial hypercholesterolaemia. Curr Opin Lipidol. 2013; 24:288-94.
-
(2013)
Curr Opin Lipidol
, vol.24
, pp. 288-294
-
-
Marais, A.D.1
Blom, D.J.2
-
5
-
-
79956267846
-
Familial hypercholesterolemia: Screening, diagnosis and management of pediatric and adult patients: Clinical guidance from the National Lipid Association expert panel on familial hypercholesterolemia
-
Goldberg AC, Hopkins PN, Toth PP et al. Familial hypercholesterolemia: screening, diagnosis and management of pediatric and adult patients: clinical guidance from the National Lipid Association expert panel on familial hypercholesterolemia. J Clin Lipidol. 2011; 5(suppl 3):S1-8.
-
(2011)
J Clin Lipidol
, vol.5
, pp. S1-S8
-
-
Goldberg, A.C.1
Hopkins, P.N.2
Toth, P.P.3
-
6
-
-
0034717836
-
Progress towards understanding the role of microsomal triglyceride transfer protein in apolipoprotein-B lipoprotein assembly
-
Gordon DA, Jamil H. Progress towards understanding the role of microsomal triglyceride transfer protein in apolipoprotein-B lipoprotein assembly. Biochim Biophys Acta. 2000; 1486:72-83.
-
(2000)
Biochim Biophys Acta
, vol.1486
, pp. 72-83
-
-
Gordon, D.A.1
Jamil, H.2
-
7
-
-
48349085741
-
Microsomal triglyceride transfer protein inhibition - Friend or foe?
-
Joy TR, Hegele RA. Microsomal triglyceride transfer protein inhibition - friend or foe? Nat Clin Pract Cardiovasc Med. 2008; 5:506-8.
-
(2008)
Nat Clin Pract Cardiovasc Med
, vol.5
, pp. 506-508
-
-
Joy, T.R.1
Hegele, R.A.2
-
8
-
-
36049025844
-
New targets and emerging therapies for reducing LDL cholesterol
-
Lilly SM, Rader DJ. New targets and emerging therapies for reducing LDL cholesterol. Curr Opin Lipidol. 2007; 18:650-5.
-
(2007)
Curr Opin Lipidol
, vol.18
, pp. 650-655
-
-
Lilly, S.M.1
Rader, D.J.2
-
10
-
-
84882927131
-
New LDL-cholesterol lowering therapies: Pharmacology, clinical trials, and relevance to acute coronary syndromes
-
Sahebkar A, Watts GF. New LDL-cholesterol lowering therapies: pharmacology, clinical trials, and relevance to acute coronary syndromes. Clin Ther. 2013; 35:1082-98.
-
(2013)
Clin Ther
, vol.35
, pp. 1082-1098
-
-
Sahebkar, A.1
Watts, G.F.2
-
11
-
-
84907225310
-
-
Food and Drug Administration. Briefing document: NDA 203858. www.fda.gov/downloads/AdvisoryCommittees/CommitteesMeetingMaterials/Drugs/EndocrinologicandMetabolicDrugsAdvisoryCommittee/UCM323841.pdf (accessed 2013 Aug 25).
-
Briefing Document: NDA 203858
-
-
-
15
-
-
84907219538
-
-
Cambridge, MA: Aegerion Pharmaceuticals, Inc.
-
Juxtapid (lomitapide) package insert. Cambridge, MA: Aegerion Pharmaceuticals, Inc.; 2012.
-
(2012)
Juxtapid (Lomitapide) Package Insert
-
-
-
16
-
-
33846151732
-
Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia
-
Cuchel M, Bloedon LT, Szapary PO et al. Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia. N Engl J Med. 2007; 356:148-56.
-
(2007)
N Engl J Med
, vol.356
, pp. 148-156
-
-
Cuchel, M.1
Bloedon, L.T.2
Szapary, P.O.3
-
17
-
-
0031128192
-
Jami l H. Microsomal triglyceride transfer protein
-
Wetterau JR, Lin MC, Jami l H. Microsomal triglyceride transfer protein. Biochim Biophys Acta. 1997; 1345:136-50.
-
(1997)
Biochim Biophys Acta
, vol.1345
, pp. 136-150
-
-
Wetterau, J.R.1
Lin, M.C.2
-
18
-
-
48349088178
-
Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia
-
Samaha FF, McKenney J, Bloedon LT et al. Inhibition of microsomal triglyceride transfer protein alone or with ezetimibe in patients with moderate hypercholesterolemia. Nat Clin Pract Cardiovasc Med. 2008; 5:497-505.
-
(2008)
Nat Clin Pract Cardiovasc Med
, vol.5
, pp. 497-505
-
-
Samaha, F.F.1
McKenney, J.2
Bloedon, L.T.3
-
19
-
-
2442502479
-
The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: One-year follow-up of a randomized trial
-
Stern L, Iqbal N, Seshadri P et al. The effects of low-carbohydrate versus conventional weight loss diets in severely obese adults: one-year follow-up of a randomized trial. Ann Intern Med. 2004; 140:778-85.
-
(2004)
Ann Intern Med
, vol.140
, pp. 778-785
-
-
Stern, L.1
Iqbal, N.2
Seshadri, P.3
-
20
-
-
0028076352
-
In vivo metabolism of apolipoproteins A-I and E in patients with abetalipoproteinemia: Implications for the roles of apolipoproteins B and E in HDL metabolism
-
Ikewaki K, Rader DJ, Zech LA, Brewer HB Jr. In vivo metabolism of apolipoproteins A-I and E in patients with abetalipoproteinemia: implications for the roles of apolipoproteins B and E in HDL metabolism. J Lipid Res. 1994; 35:1809-19.
-
(1994)
J Lipid Res
, vol.35
, pp. 1809-1819
-
-
Ikewaki, K.1
Rader, D.J.2
Zech, L.A.3
Brewer, H.B.4
-
21
-
-
0032539162
-
Intensive lifestyle changes for reversal of coronary heart disease
-
[Erratum, JAMA. 1999; 281:1380]
-
Ornish D, Scherwitz LW, Billings JH et al. Intensive lifestyle changes for reversal of coronary heart disease. JAMA. 1998; 280:2001-7. [Erratum, JAMA. 1999; 281:1380.]
-
(1998)
JAMA
, vol.280
, pp. 2001-2007
-
-
Ornish, D.1
Scherwitz, L.W.2
Billings, J.H.3
-
22
-
-
84871945617
-
Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: A single-arm, open-label, phase 3 study
-
Cuchel M, Meagher EA, du Toit Theron H et al., for the Phase 3 HoFH Lomitapide Study investigators. Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study. Lancet. 2013; 381:40-6.
-
(2013)
Lancet
, vol.381
, pp. 40-46
-
-
Cuchel, M.1
Meagher, E.A.2
Du Toit Theron, H.3
-
25
-
-
84896786524
-
Pharmacokinetic interactions of the microsomal triglyceride transfer protein inhibitor, lomitapide, with drugs commonly used in the management of hypercholesterolemia
-
Epub ahead of print. 2013 Oct 15
-
Tuteja S, Duffy D, Dunbar R et al. Pharmacokinetic interactions of the microsomal triglyceride transfer protein inhibitor, lomitapide, with drugs commonly used in the management of hypercholesterolemia. Pharmacotherapy. 2013. Epub ahead of print. 2013 Oct 15.
-
(2013)
Pharmacotherapy
-
-
Tuteja, S.1
Duffy, D.2
Dunbar, R.3
-
26
-
-
84868518061
-
Apolipoprotein B synthesis inhibition with mipomersen in heterozygous familial hypercholesterolemia: Results of a randomized, double-blind, placebo-controlled trial to assess efficacy and safety as add-on therapy in patients with coronary artery disease
-
Stein EA, Dufour R, Gagne C et al. Apolipoprotein B synthesis inhibition with mipomersen in heterozygous familial hypercholesterolemia: results of a randomized, double-blind, placebo-controlled trial to assess efficacy and safety as add-on therapy in patients with coronary artery disease. Circulation. 2012; 126:2283-92.
-
(2012)
Circulation
, vol.126
, pp. 2283-2292
-
-
Stein, E.A.1
Dufour, R.2
Gagne, C.3
-
27
-
-
84862219022
-
Safety and efficacy of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease, SAR236553/REGN727, in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy
-
McKenney JM, Koren MJ, Kereiakes DJ et al. Safety and efficacy of a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 serine protease, SAR236553/REGN727, in patients with primary hypercholesterolemia receiving ongoing stable atorvastatin therapy. J Am Coll Cardiol. 2012; 59:2344-53.
-
(2012)
J Am Coll Cardiol
, vol.59
, pp. 2344-2353
-
-
McKenney, J.M.1
Koren, M.J.2
Kereiakes, D.J.3
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