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Volumn 2017, Issue 12, 2014, Pages

Azathioprine and 6-mercaptopurine for maintenance of surgically-induced remission in Crohn's disease

Author keywords

[No Author keywords available]

Indexed keywords

ADALIMUMAB; AZATHIOPRINE; INFLIXIMAB; MERCAPTOPURINE; MESALAZINE; PLACEBO; IMMUNOSUPPRESSIVE AGENT; MONOCLONAL ANTIBODY; NONSTEROID ANTIINFLAMMATORY AGENT;

EID: 84907222744     PISSN: None     EISSN: 1469493X     Source Type: Journal    
DOI: 10.1002/14651858.CD010233.pub2     Document Type: Review
Times cited : (67)

References (43)
  • 1
    • 4444366271 scopus 로고    scopus 로고
    • Azathioprine and mesalamine for prevention of relapse after conservative surgery for Crohn's disease
    • Ardizzone S, Maconi G, Sampietro GM, Russo A, Radice E, Colombo E, et al. Azathioprine and mesalamine for prevention of relapse after conservative surgery for Crohn's disease. Gastroenterology 2004;127(3):730-40.
    • (2004) Gastroenterology , vol.127 , Issue.3 , pp. 730-740
    • Ardizzone, S.1    Maconi, G.2    Sampietro, G.M.3    Russo, A.4    Radice, E.5    Colombo, E.6
  • 2
    • 85036595130 scopus 로고    scopus 로고
    • Prevention of postoperative recurrence with azathioprine or anti-TNF alpha in patients with Crohn's disease: A pilot study
    • Armuzzi A, Felice C, Marzo M, Pugliese D, Andrisani G, Papa A, et al. Prevention of postoperative recurrence with azathioprine or anti-TNF alpha in patients with Crohn's disease: A pilot study. Digestive and Liver Disease 2012;44:S194.
    • (2012) Digestive and Liver Disease , vol.44 , pp. S194
    • Armuzzi, A.1    Felice, C.2    Marzo, M.3    Pugliese, D.4    Andrisani, G.5    Papa, A.6
  • 3
    • 84886400486 scopus 로고    scopus 로고
    • Prevention of postoperative recurrence with azathioprine or anti-TNF alpha in patients with Crohn's disease: An open-label pilot study
    • Armuzzi A, Felice C, Marzo M, Pugliese D, Andrisani G, Papa A, et al. Prevention of postoperative recurrence with azathioprine or anti-TNF alpha in patients with Crohn's disease: An open-label pilot study. Gastroenterology 2012;142(5 Suppl 1):S780.
    • (2012) Gastroenterology , vol.142 , Issue.5 , pp. S780
    • Armuzzi, A.1    Felice, C.2    Marzo, M.3    Pugliese, D.4    Andrisani, G.5    Papa, A.6
  • 4
    • 84887612557 scopus 로고    scopus 로고
    • Prevention of postoperative recurrence with azathioprine or infliximab in patients with Crohn's disease: an open-label pilot study
    • Armuzzi A, Felice C, Papa A, Marzo M, Pugliese D, Andrisani G, et al. Prevention of postoperative recurrence with azathioprine or infliximab in patients with Crohn's disease: an open-label pilot study. Journal of Crohn's and Colitis 2013;7(12):e623-9.
    • (2013) Journal of Crohn's and Colitis , vol.7 , Issue.12
    • Armuzzi, A.1    Felice, C.2    Papa, A.3    Marzo, M.4    Pugliese, D.5    Andrisani, G.6
  • 5
    • 53249097726 scopus 로고    scopus 로고
    • Therapy of metronidazole with azathioprine to prevent postoperative recurrence of Crohn's disease: a controlled randomized trial
    • D'Haens G, Vermeire S, Van Assche G, Noman M, Aerden I, Van Olmen G, et al. Therapy of metronidazole with azathioprine to prevent postoperative recurrence of Crohn's disease: a controlled randomized trial. Gastroeneterology 2008;135(4):1123-9.
    • (2008) Gastroeneterology , vol.135 , Issue.4 , pp. 1123-1129
    • D'Haens, G.1    Vermeire, S.2    Van Assche, G.3    Noman, M.4    Aerden, I.5    Van Olmen, G.6
  • 6
    • 67650306654 scopus 로고    scopus 로고
    • Combination therapy with metronidazole and azathioprine reduces severe postoperative recurrence of Crohn's disease: A double-blind controlled randomized trial
    • D'Haens GR, Noman M, Van Assche GA, Van Olmen G, Aerden I, Vermeire S, et al. Combination therapy with metronidazole and azathioprine reduces severe postoperative recurrence of Crohn's disease: A double-blind controlled randomized trial. Gastroenterology 2007;132(4 Suppl 1):A52.
    • (2007) Gastroenterology , vol.132 , Issue.4 , pp. A52
    • D'Haens, G.R.1    Noman, M.2    Van Assche, G.A.3    Van Olmen, G.4    Aerden, I.5    Vermeire, S.6
  • 7
    • 4444353986 scopus 로고    scopus 로고
    • Postoperative maintenance of Crohn's disease remission with 6-mercaptopurine, mesalamine or placebo: a 2-year trial
    • Hanauer SB, Korelitz BI, Rutgeerts P, Peppercorn MA, Thisted RA, Cohen RD, et al. Postoperative maintenance of Crohn's disease remission with 6-mercaptopurine, mesalamine or placebo: a 2-year trial. Gastroenterology 2004;127(3):723-9.
    • (2004) Gastroenterology , vol.127 , Issue.3 , pp. 723-729
    • Hanauer, S.B.1    Korelitz, B.I.2    Rutgeerts, P.3    Peppercorn, M.A.4    Thisted, R.A.5    Cohen, R.D.6
  • 8
    • 0001540309 scopus 로고    scopus 로고
    • Post-operative prophylaxis with 6-MP, 5-ASA or placebo in Crohn's disease: A 2 year multicenter trial
    • Korelitz B, Hanauer S, Rutgeerts P, Present D, Peppercorn M. Post-operative prophylaxis with 6-MP, 5-ASA or placebo in Crohn's disease: A 2 year multicenter trial. Gastroenterology 1998;114(4 Part 2):A486.
    • (1998) Gastroenterology , vol.114 , Issue.4 , pp. A486
    • Korelitz, B.1    Hanauer, S.2    Rutgeerts, P.3    Present, D.4    Peppercorn, M.5
  • 9
    • 33847153405 scopus 로고    scopus 로고
    • Monitoring of thiopurine methyltransferase activity in postsurgical patients with Crohn's disease during 1 year of treatment with azathioprine or mesalazine
    • Dilger K, Schaeffeler E, Lukas M, Strauch U, Herfarth H, Muller R, et al. Monitoring of thiopurine methyltransferase activity in postsurgical patients with Crohn's disease during 1 year of treatment with azathioprine or mesalazine. Therapeutic Drug Monitoring 2007;29(1):1-5.
    • (2007) Therapeutic Drug Monitoring , vol.29 , Issue.1 , pp. 1-5
    • Dilger, K.1    Schaeffeler, E.2    Lukas, M.3    Strauch, U.4    Herfarth, H.5    Muller, R.6
  • 10
    • 85036534570 scopus 로고    scopus 로고
    • Double-blind, double dummy, randomized, multicentre, comparative study on the efficacy and safety of azathioprine (AZA) versus mesalazine (5-ASA) for prevention of postoperative endoscopic recurrence in Crohn's disease
    • Herfarth H, Obermeier F, Tjaden C, Lukas M, Serclova Z, Dignass AU, et al. Double-blind, double dummy, randomized, multicentre, comparative study on the efficacy and safety of azathioprine (AZA) versus mesalazine (5-ASA) for prevention of postoperative endoscopic recurrence in Crohn's disease. Gastroenterology 2006;130(4 Suppl 2):A480-1.
    • (2006) Gastroenterology , vol.130 , Issue.4 , pp. A480-A481
    • Herfarth, H.1    Obermeier, F.2    Tjaden, C.3    Lukas, M.4    Serclova, Z.5    Dignass, A.U.6
  • 11
    • 33749189358 scopus 로고    scopus 로고
    • Adverse events in clinical trials with azathioprine and mesalamine for the prevention of postoperative recurrence of Crohn's disease
    • Herfarth H, Tjaden C, Lukas M, Obermeier F, Dilger K, Muller R, et al. Adverse events in clinical trials with azathioprine and mesalamine for the prevention of postoperative recurrence of Crohn's disease. Gut 2006;55(10):1525-6.
    • (2006) Gut , vol.55 , Issue.10 , pp. 1525-1526
    • Herfarth, H.1    Tjaden, C.2    Lukas, M.3    Obermeier, F.4    Dilger, K.5    Muller, R.6
  • 12
    • 84876403700 scopus 로고    scopus 로고
    • Mucosal improvement in patients with moderate to severe postoperative endoscopic recurrence of Crohn's disease and azathioprine metabolite levels
    • Angelberger S, Schaeffeler E, Teml A, Petritsch W, Shonova O, Lukas M, et al. Mucosal improvement in patients with moderate to severe postoperative endoscopic recurrence of Crohn's disease and azathioprine metabolite levels. Inflammatory Bowel Diseases 2013;19(3):590-8.
    • (2013) Inflammatory Bowel Diseases , vol.19 , Issue.3 , pp. 590-598
    • Angelberger, S.1    Schaeffeler, E.2    Teml, A.3    Petritsch, W.4    Shonova, O.5    Lukas, M.6
  • 13
    • 85036506421 scopus 로고    scopus 로고
    • Relationship between thiopurine metabolite levels and endoscopic improvement in patients with postoperative moderate to severe endoscopic recurrence of Crohn's disease
    • Angelberger S, Schaeffeler E, Teml A, Petritsch W, Shonova O, Lukas M, et al. Relationship between thiopurine metabolite levels and endoscopic improvement in patients with postoperative moderate to severe endoscopic recurrence of Crohn's disease. Gastroenterology 2010;138(5 Suppl 1):S685.
    • (2010) Gastroenterology , vol.138 , Issue.5 , pp. S685
    • Angelberger, S.1    Schaeffeler, E.2    Teml, A.3    Petritsch, W.4    Shonova, O.5    Lukas, M.6
  • 14
    • 75149172302 scopus 로고    scopus 로고
    • A double-blind, double-dummy, randomized, controlled, multicenter trial on the efficacy and safety of azathioprine vs mesalamine for prevention of clinical relapses in Crohn's disease patients with postoperative moderate or severe endoscopic recurrence
    • Reinisch W, Angelberger S, Petritsch W, Herrlinger K, Shonova O, Lukas M, et al. A double-blind, double-dummy, randomized, controlled, multicenter trial on the efficacy and safety of azathioprine vs mesalamine for prevention of clinical relapses in Crohn's disease patients with postoperative moderate or severe endoscopic recurrence. Gastroenterology 2008;134(4 Suppl 1):A70.
    • (2008) Gastroenterology , vol.134 , Issue.4 , pp. A70
    • Reinisch, W.1    Angelberger, S.2    Petritsch, W.3    Herrlinger, K.4    Shonova, O.5    Lukas, M.6
  • 15
    • 77953726380 scopus 로고    scopus 로고
    • Azathioprine versus mesalazine for the prevention of postoperative clinical recurrence in patients with Crohn's disease with endoscopic recurrence: efficacy and safety results of a randomized, double-blind, double-dummy, multicentre trial
    • Reinisch W, Angelberger S, Petritsch W, Shonova O, Lukas M, Bar-Meir S, et al. Azathioprine versus mesalazine for the prevention of postoperative clinical recurrence in patients with Crohn's disease with endoscopic recurrence: efficacy and safety results of a randomized, double-blind, double-dummy, multicentre trial. Gut 2010;59(6):752-9.
    • (2010) Gut , vol.59 , Issue.6 , pp. 752-759
    • Reinisch, W.1    Angelberger, S.2    Petritsch, W.3    Shonova, O.4    Lukas, M.5    Bar-Meir, S.6
  • 16
    • 85036506857 scopus 로고    scopus 로고
    • Azathioprine versus mesalazine for prevention of postoperative clinical recurrence in Crohn's disease patients with endoscopic recurrence: Follow-up data of a randomised, double-blind, double-dummy, 1-year, multicentre trial
    • Reinisch W, Angelberger S, Petritsch W, Shonova O, Lukas M, Greinwald R, et al. Azathioprine versus mesalazine for prevention of postoperative clinical recurrence in Crohn's disease patients with endoscopic recurrence: Follow-up data of a randomised, double-blind, double-dummy, 1-year, multicentre trial. Journal of Crohn's and Colitis 2013;7:S254.
    • (2013) Journal of Crohn's and Colitis , vol.7 , pp. S254
    • Reinisch, W.1    Angelberger, S.2    Petritsch, W.3    Shonova, O.4    Lukas, M.5    Greinwald, R.6
  • 17
    • 79953759042 scopus 로고    scopus 로고
    • Efficacy of azathioprine versus mesalazine in postoperative Crohn's disease - the authors' response
    • Reinisch W, Stange EF. Efficacy of azathioprine versus mesalazine in postoperative Crohn's disease - the authors' response. Gut 2011;60(5):739-40.
    • (2011) Gut , vol.60 , Issue.5 , pp. 739-740
    • Reinisch, W.1    Stange, E.F.2
  • 18
    • 85036520646 scopus 로고    scopus 로고
    • Adalimumab is more effective than azathioprine and mesalamine at preventing postoperative recurrence of Crohn's disease - a randomized trial
    • Savarino E, Bodini G, Dulbecco P, Assandri L, Bruzzone L, Mazza F. Adalimumab is more effective than azathioprine and mesalamine at preventing postoperative recurrence of Crohn's disease - a randomized trial. Digestive and Liver Disease 2013;45:S94-5.
    • (2013) Digestive and Liver Disease , vol.45 , pp. S94-S95
    • Savarino, E.1    Bodini, G.2    Dulbecco, P.3    Assandri, L.4    Bruzzone, L.5    Mazza, F.6
  • 19
    • 84887237442 scopus 로고    scopus 로고
    • Adalimumab is more effective than azathioprine and mesalamine at preventing postoperative recurrence of Crohn's disease: a randomized controlled trial
    • Savarino E, Bodini G, Dulbecco P, Assandri L, Bruzzone L, Mazza F, et al. Adalimumab is more effective than azathioprine and mesalamine at preventing postoperative recurrence of Crohn's disease: a randomized controlled trial. American Journal of Gastroenterology 2013;108(11):1731-42.
    • (2013) American Journal of Gastroenterology , vol.108 , Issue.11 , pp. 1731-1742
    • Savarino, E.1    Bodini, G.2    Dulbecco, P.3    Assandri, L.4    Bruzzone, L.5    Mazza, F.6
  • 20
    • 84884366323 scopus 로고    scopus 로고
    • Adalimumab is more effective than azathioprine and mesalamine at preventing postoperative recurrence of Crohn's disease - a randomized trial
    • Savarino E, Bodini G, Dulbecco P, Marabotto E, Assandri L, Bruzzone L. Adalimumab is more effective than azathioprine and mesalamine at preventing postoperative recurrence of Crohn's disease - a randomized trial. Gastroenterology 2013;144(5 Suppl 1):S21.
    • (2013) Gastroenterology , vol.144 , Issue.5 , pp. S21
    • Savarino, E.1    Bodini, G.2    Dulbecco, P.3    Marabotto, E.4    Assandri, L.5    Bruzzone, L.6
  • 21
  • 22
    • 85036497051 scopus 로고    scopus 로고
    • Azathioprine versus azathioprine plus metronidazole for the prevention of postoperative endoscopic recurrence of Crohn's disease: A randomized, placebo-controlled trial
    • Manosa M, Cabre E, Bernal I, Esteve M, Garcia- Planella E, Ricart Gomez E. Azathioprine versus azathioprine plus metronidazole for the prevention of postoperative endoscopic recurrence of Crohn's disease: A randomized, placebo-controlled trial. Journal of Crohn's and Colitis 2012;6:S93.
    • (2012) Journal of Crohn's and Colitis , vol.6 , pp. S93
    • Manosa, M.1    Cabre, E.2    Bernal, I.3    Esteve, M.4    Garcia-Planella, E.5    Ricart Gomez, E.6
  • 23
    • 84884612439 scopus 로고    scopus 로고
    • Addition of metronidazole to azathioprine for the prevention of postoperative recurrence of Crohn's disease: a randomized, double-blind, placebo-controlled trial
    • Mañosa M, Cabré E, Bernal I, Esteve M, Garcia-Planella E, Ricart E, et al. Addition of metronidazole to azathioprine for the prevention of postoperative recurrence of Crohn's disease: a randomized, double-blind, placebo-controlled trial. Inflammatory Bowel Diseases 2013;19(9):1889-95.
    • (2013) Inflammatory Bowel Diseases , vol.19 , Issue.9 , pp. 1889-1895
    • Mañosa, M.1    Cabré, E.2    Bernal, I.3    Esteve, M.4    Garcia-Planella, E.5    Ricart, E.6
  • 26
    • 0033971379 scopus 로고    scopus 로고
    • Risk factors for surgery and postoperative recurrence in Crohn's disease
    • Bernell O, Lapidus A, Hellers G. Risk factors for surgery and postoperative recurrence in Crohn's disease. Annals of Surgery 2000;231(1):38-45.
    • (2000) Annals of Surgery , vol.231 , Issue.1 , pp. 38-45
    • Bernell, O.1    Lapidus, A.2    Hellers, G.3
  • 27
    • 0028293868 scopus 로고
    • The role of leukopenia in the 6-mercaptopurine induced remission of refractory Crohn's disease
    • Colonna T, Korelitz BI. The role of leukopenia in the 6-mercaptopurine induced remission of refractory Crohn's disease. American Journal of Gastroenterology 1994;89(3):362-6.
    • (1994) American Journal of Gastroenterology , vol.89 , Issue.3 , pp. 362-366
    • Colonna, T.1    Korelitz, B.I.2
  • 29
    • 79952267166 scopus 로고    scopus 로고
    • Oral 5-aminosalicylic acid for maintenance of surgically-induced remission in Crohn's disease
    • Gordon M, Naidoo K, Thomas AG, Akobeng AK. Oral 5-aminosalicylic acid for maintenance of surgically-induced remission in Crohn's disease. Cochrane Database of Systematic Reviews 2011, Issue 1. [DOI: 10.1002/14651858.CD008414.pub2]
    • (2011) Cochrane Database of Systematic Reviews , Issue.1
    • Gordon, M.1    Naidoo, K.2    Thomas, A.G.3    Akobeng, A.K.4
  • 30
    • 43049113533 scopus 로고    scopus 로고
    • GRADE: an emerging consensus on rating quality of evidence and strength of recommendations
    • Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, et al. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 2008;336(7650):924-6.
    • (2008) BMJ , vol.336 , Issue.7650 , pp. 924-926
    • Guyatt, G.H.1    Oxman, A.D.2    Vist, G.E.3    Kunz, R.4    Falck-Ytter, Y.5    Alonso-Coello, P.6
  • 31
    • 0036189430 scopus 로고    scopus 로고
    • Le mycophénolate mofétil dans les formes chroniques actives de la maladie de Crohn après échec de lazathioprine ou du méthotrexate
    • Hafraoui S, Dewit O, Marteau P, Cosnes J, Colombel JF, Modigliani R, et al. Mycophenolate mofetil in refractory Crohn's disease after failure of treatments by azathioprine or methotrexate [Le mycophénolate mofétil dans les formes chroniques actives de la maladie de Crohn après échec de lazathioprine ou du méthotrexate]. Gastroenterologie Clinique et Biologique 2002;26(1):17-22.
    • (2002) Gastroenterologie Clinique et Biologique , vol.26 , Issue.1 , pp. 17-22
    • Hafraoui, S.1    Dewit, O.2    Marteau, P.3    Cosnes, J.4    Colombel, J.F.5    Modigliani, R.6
  • 33
    • 0041876133 scopus 로고    scopus 로고
    • Measuring inconsistency in meta-analyses
    • Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003;327(7414):557-60.
    • (2003) BMJ , vol.327 , Issue.7414 , pp. 557-560
    • Higgins, J.P.1    Thompson, S.G.2    Deeks, J.J.3    Altman, D.G.4
  • 35
    • 0033620411 scopus 로고    scopus 로고
    • Accuracy of data in abstracts of published research articles
    • Pitkin RM, Branagan MA, Burmeister LF. Accuracy of data in abstracts of published research articles. JAMA 1999;281(12):1110-1.
    • (1999) JAMA , vol.281 , Issue.12 , pp. 1110-1111
    • Pitkin, R.M.1    Branagan, M.A.2    Burmeister, L.F.3
  • 38
    • 84964921069 scopus 로고    scopus 로고
    • Review Manager (RevMan)
    • Version 5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration
    • The Nordic Cochrane Centre, The Cochrane Collaboration. Review Manager (RevMan). Version 5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2014.
    • (2014)


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