The effect of calcium supplementation on bone density during lactation and after weaning

New England Journal of Medicine

Volumn 337, Issue 8, 1997, Pages 523-528

  Kalkwarf, Heidi J ^a,b   Specker, Bonny L ^a   Bianchi, Donna C ^a   Ranz, Julie ^a   Ho, Mona ^a  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CARBONATE; LACTOSE; PLACEBO;

ADULT; ARTICLE; BONE DENSITY; BONE MINERAL; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; FEMALE; FOREARM; HUMAN; LACTATION; LUMBAR SPINE; MAJOR CLINICAL STUDY; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; WEANING;

ADULT; BONE DENSITY; BONE REGENERATION; BONE RESORPTION; CALCIUM CARBONATE; CALCIUM, DIETARY; DOUBLE-BLIND METHOD; FEMALE; HUMANS; LACTATION; LUMBAR VERTEBRAE; POSTPARTUM PERIOD; RADIUS; WEANING;

EID: 0030877583     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM199708213370803     Document Type: Article

References (27)

1. Subcommittee on the Tenth Edition of the RDAs. Recommended dietary allowances. 10th ed. Washington, D.C.: National Academy Press, 1989.
2. Hayslip CC, Klein TA, Wray HL, Duncan WE. The effects of lactation on bone mineral content in healthy postpartum women. Obstet Gynecol 1989;73:588-92.
3. Kalkwarf HJ, Specker BL. Bone mineral loss during lactation and recovery after weaning. Obstet Gynecol 1995;86:26-32.
4. Hopkinson J, Butte N, Ellis K, Heinz C, Shypaillo R. Recovery of bone mineral density during lactation. FASEB J 1995;9:A85. abstract.
5. Sowers MF, Corton G, Shapiro B, et al. Changes in bone density with lactation. JAMA 1993;269:3130-5.
6. Affinito P, Tommaselli GA, di Carlo C, Guida F, Nappi C. Changes in bone mineral density and calcium metabolism in breastfeeding women: a one year follow-up study. J Clin Endocrinol Metab 1996;81:2314-8.
7. Kent GN, Price RI, Gutteridge DH, et al. Human lactation: forearm trabecular bone loss, increased bone turnover, and renal conservation of calcium and inorganic phosphate with recovery of bone mass following weaning. J Bone Miner Res 1990;5:361-9.
8. Lopez JM, Gonzalez G, Reyes V, Campino C, Diaz S. Bone turnover and density in healthy women during breastfeeding and after weaning. Osteoporos Int 1996;6:153-9.
9. Lissner L, Bengtsson C, Hansson T. Bone mineral content in relation to lactation history in pre-and postmenopausal women. Calcif Tissue Int 1991;48:319-25.
10. Wardlaw GM, Pike AM. The effect of lactation on peak adult shaft and ultra-distal forearm bone mass in women. Am J Clin Nutr 1986;44:283-6. [Erratum, Am J Clin Nutr 1986;44:1002.]
11. Hreshchyshyn MM, Hopkins A, Zylstra S, Anbar M. Associations of parity, breast-feeding, and birth control pills with lumbar spine and femoral neck bone densities. Am J Obstet Gynecol 1988;159:318-22.
12. Kritz-Silverstein D, Barrett-Connor E, Hollenbach KA. Pregnancy and lactation as determinants of bone mineral density in postmenopausal women. Am J Epidemiol 1992;136:1052-9.
13. Melton LJ III, Bryant SC, Wahner HW, et al. Influence of breastfeeding and other reproductive factors on bone mass later in life. Osteoporos Int 1993;3:76-83.
14. Feldblum PJ, Zhang J, Rich LE, Fortney JA, Talmage RV. Lactation history and bone mineral density among perimenopausal women. Epidemiology 1992;3:527-31.
15. Walker ARP, Richardson B, Walker F. The influence of numerous pregnancies and lactations on bone dimensions in South African Bantu and Caucasian mothers. Clin Sci 1972;42:189-96.
16. Koetting CA, Wardlaw GM. Wrist, spine, and hip bone density in women with variable histories of lactation. Am J Clin Nutr 1988;48:1479-81.
17. Sinigaglia L, Varenna M, Binelli L, Gallazzi M, Calori G, Ranza R. Effect of lactation on postmenopausal bone mineral density of the lumbar spine. J Reprod Med 1996;41:439-43.
18. Fox KM, Magaziner J, Sherwin R, et al. Reproductive correlates of bone mass in elderly women: Study of Osteoporotic Fractures Research Group. J Bone Miner Res 1993;8:901-8.
19. Cross NA, Hillman LS, Allen SH, Krause GF. Changes in bone mineral density and markers of bone remodeling during lactation and postweaning in women consuming high amounts of calcium. J Bone Miner Res 1995;10:1312-20.
20. Prentice A, Jarjou LMA, Cole TJ, Stirling DM, Dibba B, Fairweather-Tait S. Calcium requirements of lactating Gambian mothers: effects of a calcium supplement on breast-milk calcium concentration, maternal bone mineral content, and urinary calcium excretion. Am J Clin Nutr 1995;62: 58-67.
21. Cummings SR, Block G, McHenry K, Baron RB. Evaluation of two food frequency methods of measuring dietary calcium intake. Am J Epidemiol 1987;126:796-802.
22. Sowers MF, Hollis BW, Shapiro B, et al. Elevated parathyroid hormone-related peptide associated with lactation and bone density loss. JAMA 1996;276:549-54.
23. Lippuner K, Zehnder H-J, Casez J-P, Takkinen R, Jaeger P. PTH-related protein is released into the mother's bloodstream during lactation: evidence for beneficial effects on maternal calcium-phosphate metabolism. J Bone Miner Res 1996;11:1394-9.
24. Dobnig H, Kainer F, Stepan V, et al. Elevated parathyroid hormone-related peptide levels after human gestation: relationship to changes in bone and mineral metabolism. J Clin Endocrinol Metab 1995;80:3699-707.
25. Kalkwarf HJ, Specker BL, Heubi JE, Vieira NE, Yergey AL. Intestinal calcium absorption of women during lactation and after weaning. Am J Clin Nutr 1996;63:526-31.
26. Moser PB, Reynolds RD, Acharya S, Howard MP, Andon MB. Calcium and magnesium dietary intakes and plasma and milk concentrations of Nepalese lactating women. Am J Clin Nutr 1988;47:735-9.
27. Karra MV, Kirksey A, Galal O, Bassily NS, Harrison GG, Jerome NW. Zinc, calcium, and magnesium concentrations in milk from American and Egyptian women throughout the first 6 months of lactation. Am J Clin Nutr 1988;47:642-8.