-
1
-
-
79952232216
-
Global cancer statistics
-
doi:10.3322/caac.20107
-
Jemal A, Bray F, Center MM, Ferlay J, Ward E, et al. (2011) Global cancer statistics. CA Cancer J Clin 61: 69-90. doi:10.3322/caac.20107.
-
(2011)
CA Cancer J Clin
, vol.61
, pp. 69-90
-
-
Jemal, A.1
Bray, F.2
Center, M.M.3
Ferlay, J.4
Ward, E.5
-
2
-
-
84874115779
-
Epidermal growth factor receptor inhibition in lung cancer: Status 2012
-
doi:10.1097/JTO.0b013e31827ed0ff
-
Hirsch FR, Janne PA, Eberhardt WE, Cappuzzo F, Thatcher N, et al. (2013) Epidermal growth factor receptor inhibition in lung cancer: status 2012. J Thorac Oncol 8: 373-384. doi:10.1097/JTO.0b013e31827ed0ff.
-
(2013)
J Thorac Oncol
, vol.8
, pp. 373-384
-
-
Hirsch, F.R.1
Janne, P.A.2
Eberhardt, W.E.3
Cappuzzo, F.4
Thatcher, N.5
-
3
-
-
82555205501
-
New strategies for treatment of ALK-rearranged nonsmall cell lung cancers
-
doi:10.1158/1078-0432.CCR-11-1404
-
Sasaki T, Janne PA (2011) New strategies for treatment of ALK-rearranged nonsmall cell lung cancers. Clin Cancer Res 17: 7213-7218. doi:10.1158/1078-0432.CCR-11-1404.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 7213-7218
-
-
Sasaki, T.1
Janne, P.A.2
-
4
-
-
79951862254
-
The evolving role of histology in the management of advanced non-small-cell lung cancer
-
doi:10.1200/JCO.2010.28.8126
-
Langer CJ, Besse B, Gualberto A, Brambilla E, Soria JC (2010) The evolving role of histology in the management of advanced non-small-cell lung cancer. J Clin Oncol 28: 5311-5320. doi:10.1200/JCO.2010.28.8126.
-
(2010)
J Clin Oncol
, vol.28
, pp. 5311-5320
-
-
Langer, C.J.1
Besse, B.2
Gualberto, A.3
Brambilla, E.4
Soria, J.C.5
-
5
-
-
73649102105
-
Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC
-
doi:10.1016/j.ccr.2009.11.022
-
Turke AB, Zejnullahu K, Wu YL, Song Y, Dias-Santagata D, et al. (2010) Preexistence and clonal selection of MET amplification in EGFR mutant NSCLC. Cancer Cell 17: 77-88. doi:10.1016/j.ccr.2009.11.022.
-
(2010)
Cancer Cell
, vol.17
, pp. 77-88
-
-
Turke, A.B.1
Zejnullahu, K.2
Wu, Y.L.3
Song, Y.4
Dias-Santagata, D.5
-
6
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling
-
doi:10.1126/science.1141478
-
Engelman JA, Zejnullahu K, Mitsudomi T, Song Y, Hyland C, et al. (2007) MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling. Science 316: 1039-1043. doi:10.1126/science.1141478.
-
(2007)
Science
, vol.316
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
Song, Y.4
Hyland, C.5
-
7
-
-
0027322529
-
Hepatocyte growth factor/scatter factor stimulates the Ras-guanine nucleotide exchanger
-
PMID: 8387483
-
Graziani A, Gramaglia D, dalla Zonca P, Comoglio PM (1993) Hepatocyte growth factor/scatter factor stimulates the Ras-guanine nucleotide exchanger. J Biol Chem 268: 9165-9168. PMID: 8387483.
-
(1993)
J Biol Chem
, vol.268
, pp. 9165-9168
-
-
Graziani, A.1
Gramaglia, D.2
Dalla Zonca, P.3
Comoglio, P.M.4
-
8
-
-
33745465488
-
Hepatocyte growth factor and the Met system as a mediator of tumor-stromal interactions
-
doi:10.1002/ijc.21808
-
Matsumoto K, Nakamura T (2006) Hepatocyte growth factor and the Met system as a mediator of tumor-stromal interactions. Int J Cancer 119: 477-483. doi:10.1002/ijc.21808.
-
(2006)
Int J Cancer
, vol.119
, pp. 477-483
-
-
Matsumoto, K.1
Nakamura, T.2
-
9
-
-
0037050212
-
Requirement of Stat3 signaling for HGF/SF-Met mediated tumorigenesis
-
doi:10.1038/sj/onc/1205004
-
Zhang YW, Wang LM, Jove R, Vande Woude GF (2002) Requirement of Stat3 signaling for HGF/SF-Met mediated tumorigenesis. Oncogene 21: 217-226. doi:10.1038/sj/onc/1205004.
-
(2002)
Oncogene
, vol.21
, pp. 217-226
-
-
Zhang, Y.W.1
Wang, L.M.2
Jove, R.3
Vande Woude, G.F.4
-
10
-
-
0032518375
-
Induction of epithelial tubules by growth factor HGF depends on the STAT pathway
-
doi:10.1038/34657
-
Boccaccio C, Ando M, Tamagnone L, Bardelli A, Michieli P, et al. (1998) Induction of epithelial tubules by growth factor HGF depends on the STAT pathway. Nature 391: 285-288. doi:10.1038/34657.
-
(1998)
Nature
, vol.391
, pp. 285-288
-
-
Boccaccio, C.1
Ando, M.2
Tamagnone, L.3
Bardelli, A.4
Michieli, P.5
-
11
-
-
80051974548
-
Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer
-
doi:10.1200/JCO.2010.34.0570
-
Sequist LV, von Pawel J, Garmey EG, Akerley WL, Brugger W, et al. (2011) Randomized phase II study of erlotinib plus tivantinib versus erlotinib plus placebo in previously treated non-small-cell lung cancer. J Clin Oncol 29: 3307-3315. doi:10.1200/JCO.2010.34.0570.
-
(2011)
J Clin Oncol
, vol.29
, pp. 3307-3315
-
-
Sequist, L.V.1
Von Pawel, J.2
Garmey, E.G.3
Akerley, W.L.4
Brugger, W.5
-
12
-
-
84890108571
-
Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer
-
doi:10.1200/JCO.2012.47.4189
-
Spigel DR, Ervin TJ, Ramlau RA, Daniel DB, Goldschmidt JH Jr, et al. (2013) Randomized phase II trial of Onartuzumab in combination with erlotinib in patients with advanced non-small-cell lung cancer. J Clin Oncol 31: 4105-4114. doi:10.1200/JCO.2012.47.4189.
-
(2013)
J Clin Oncol
, vol.31
, pp. 4105-4114
-
-
Spigel, D.R.1
Ervin, T.J.2
Ramlau, R.A.3
Daniel, D.B.4
Goldschmidt, J.H.5
-
13
-
-
17944380542
-
Role of p53 as a prognostic factor for survival in lung cancer: A systematic review of the literature with a meta-analysis
-
PMID: 11716177
-
Steels E, Paesmans M, Berghmans T, Branle F, Lemaitre F, et al. (2001) Role of p53 as a prognostic factor for survival in lung cancer: a systematic review of the literature with a meta-analysis. Eur Respir J 18: 705-719. PMID: 11716177.
-
(2001)
Eur Respir J
, vol.18
, pp. 705-719
-
-
Steels, E.1
Paesmans, M.2
Berghmans, T.3
Branle, F.4
Lemaitre, F.5
-
14
-
-
55449116539
-
Met gene copy number predicts the prognosis for completely resected non-small cell lung cancer
-
doi:10.1111/j.1349-7006.2008.00916.x
-
Okuda K, Sasaki H, Yukiue H, Yano M, Fujii Y (2008) Met gene copy number predicts the prognosis for completely resected non-small cell lung cancer. Cancer Sci 99: 2280-2285. doi:10.1111/j.1349-7006.2008.00916.x.
-
(2008)
Cancer Sci
, vol.99
, pp. 2280-2285
-
-
Okuda, K.1
Sasaki, H.2
Yukiue, H.3
Yano, M.4
Fujii, Y.5
-
15
-
-
84896718478
-
MET Gene copy number gain is an independent poor prognostic marker in korean stage i lung adenocarcinomas
-
doi:10.1245/s10434-013-3355-1
-
Jin Y, Sun PL, Kim H, Seo AN, Jheon S, et al. (2013) MET Gene Copy Number Gain is an Independent Poor Prognostic Marker in Korean Stage I Lung Adenocarcinomas. Ann Surg Oncol. doi:10.1245/s10434-013-3355-1.
-
(2013)
Ann Surg Oncol
-
-
Jin, Y.1
Sun, P.L.2
Kim, H.3
Seo, A.N.4
Jheon, S.5
-
16
-
-
83555165138
-
Co-existence of positive MET FISH status with EGFR mutations signifies poor prognosis in lung adenocarcinoma patients
-
doi:10.1016/j.lungcan.2011.06.004
-
Tanaka A, Sueoka-Aragane N, Nakamura T, Takeda Y, Mitsuoka M, et al. (2012) Co-existence of positive MET FISH status with EGFR mutations signifies poor prognosis in lung adenocarcinoma patients. Lung Cancer 75: 89-94. doi:10.1016/j.lungcan.2011.06.004.
-
(2012)
Lung Cancer
, vol.75
, pp. 89-94
-
-
Tanaka, A.1
Sueoka-Aragane, N.2
Nakamura, T.3
Takeda, Y.4
Mitsuoka, M.5
-
17
-
-
70350094241
-
MET, HGF, EGFR, and PXN gene copy number in lung cancer using DNA extracts from FFPE archival samples and prognostic significance
-
PMID: 19817696
-
Kanteti R, Yala S, Ferguson MK, Salgia R (2009) MET, HGF, EGFR, and PXN gene copy number in lung cancer using DNA extracts from FFPE archival samples and prognostic significance. J Environ Pathol Toxicol Oncol 28: 89-98. PMID: 19817696.
-
(2009)
J Environ Pathol Toxicol Oncol
, vol.28
, pp. 89-98
-
-
Kanteti, R.1
Yala, S.2
Ferguson, M.K.3
Salgia, R.4
-
18
-
-
84863229341
-
High MET copy number and MET overexpression: Poor outcome in non-small cell lung cancer patients
-
PMID: 22207554
-
Park S, Choi YL, Sung CO, An J, Seo J, et al. (2012) High MET copy number and MET overexpression: poor outcome in non-small cell lung cancer patients. Histol Histopathol 27: 197-207. PMID: 22207554.
-
(2012)
Histol Histopathol
, vol.27
, pp. 197-207
-
-
Park, S.1
Choi, Y.L.2
Sung, C.O.3
An, J.4
Seo, J.5
-
19
-
-
84890264356
-
Prognostic value of MET, cyclin D1 and MET gene copy number in non-small cell lung cancer
-
doi:10.7555/JBR.27.20130004
-
Sun W, Song L, Ai T, Zhang Y, Gao Y, et al. (2013) Prognostic value of MET, cyclin D1 and MET gene copy number in non-small cell lung cancer. J Biomed Res 27: 220-230. doi:10.7555/JBR.27.20130004.
-
(2013)
J Biomed Res
, vol.27
, pp. 220-230
-
-
Sun, W.1
Song, L.2
Ai, T.3
Zhang, Y.4
Gao, Y.5
-
20
-
-
84858335323
-
C-MET/phospho-MET protein expression and MET gene copy number in non-small cell lung carcinomas
-
doi:10.1097/JTO.0-b013e318241655f
-
Tsuta K, Kozu Y, Mimae T, Yoshida A, Kohno T, et al. (2012) c-MET/phospho-MET protein expression and MET gene copy number in non-small cell lung carcinomas. J Thorac Oncol 7: 331-339. doi:10.1097/JTO.0-b013e318241655f.
-
(2012)
J Thorac Oncol
, vol.7
, pp. 331-339
-
-
Tsuta, K.1
Kozu, Y.2
Mimae, T.3
Yoshida, A.4
Kohno, T.5
-
21
-
-
63849163410
-
Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients
-
doi:10.1200/JCO.2008.19.1635
-
Cappuzzo F, Marchetti A, Skokan M, Rossi E, Gajapathy S, et al. (2009) Increased MET gene copy number negatively affects survival of surgically resected non-small-cell lung cancer patients. J Clin Oncol 27: 1667-1674. doi:10.1200/JCO.2008.19.1635.
-
(2009)
J Clin Oncol
, vol.27
, pp. 1667-1674
-
-
Cappuzzo, F.1
Marchetti, A.2
Skokan, M.3
Rossi, E.4
Gajapathy, S.5
-
22
-
-
81755165799
-
Clinical implications of high MET gene dosage in non-small cell lung cancer patients without previous tyrosine kinase inhibitor treatment
-
doi:10.1097/JTO.0b013e3182307e92
-
Chen YT, Chang JW, Liu HP, Yu TF, Chiu YT, et al. (2011) Clinical implications of high MET gene dosage in non-small cell lung cancer patients without previous tyrosine kinase inhibitor treatment. J Thorac Oncol 6: 2027-2035. doi:10.1097/JTO.0b013e3182307e92.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 2027-2035
-
-
Chen, Y.T.1
Chang, J.W.2
Liu, H.P.3
Yu, T.F.4
Chiu, Y.T.5
-
23
-
-
84862777005
-
Correlation between MET gene copy number by silver in situ hybridization and protein expression by immunohistochemistry in non-small cell lung cancer
-
doi:10.1097/JTO.0b013e318240-ca0d
-
Dziadziuszko R, Wynes MW, Singh S, Asuncion BR, Ranger-Moore J, et al. (2012) Correlation between MET gene copy number by silver in situ hybridization and protein expression by immunohistochemistry in non-small cell lung cancer. J Thorac Oncol 7: 340-347. doi:10.1097/JTO.0b013e318240-ca0d.
-
(2012)
J Thorac Oncol
, vol.7
, pp. 340-347
-
-
Dziadziuszko, R.1
Wynes, M.W.2
Singh, S.3
Asuncion, B.R.4
Ranger-Moore, J.5
-
24
-
-
77649308276
-
High MET gene copy number leads to shorter survival in patients with non-small cell lung cancer
-
doi:10.1097/JTO.0b013e3181ce3d1d
-
Go H, Jeon YK, Park HJ, Sung SW, Seo JW, et al. (2010) High MET gene copy number leads to shorter survival in patients with non-small cell lung cancer. J Thorac Oncol 5: 305-313. doi:10.1097/JTO.0b013e3181ce3d1d.
-
(2010)
J Thorac Oncol
, vol.5
, pp. 305-313
-
-
Go, H.1
Jeon, Y.K.2
Park, H.J.3
Sung, S.W.4
Seo, J.W.5
-
25
-
-
84855466095
-
Abnormality of the hepatocyte growth factor/MET pathway in pulmonary adenocarcinogenesis
-
Tachibana K, Minami Y, Shiba-Ishii A, Kano J, Nakazato Y, et al. (2012) Abnormality of the hepatocyte growth factor/MET pathway in pulmonary adenocarcinogenesis. Lung Cancer 75: 181-188.
-
(2012)
Lung Cancer
, vol.75
, pp. 181-188
-
-
Tachibana, K.1
Minami, Y.2
Shiba-Ishii, A.3
Kano, J.4
Nakazato, Y.5
-
26
-
-
0037699512
-
Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells
-
doi:10.1016/j.lungcan.2011.07.008
-
Song L, Turkson J, Karras JG, Jove R, Haura EB (2003) Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells. Oncogene 22: 4150-4165. doi:10.1016/j.lungcan.2011.07.008.
-
(2003)
Oncogene
, vol.22
, pp. 4150-4165
-
-
Song, L.1
Turkson, J.2
Karras, J.G.3
Jove, R.4
Haura, E.B.5
-
27
-
-
84874782595
-
Biomarkers of residual disease, disseminated tumor cells, and metastases in the MMTV-PyMT breast cancer model
-
doi:10.1371/journal.pone.0058183
-
Franci C, Zhou J, Jiang Z, Modrusan Z, Good Z, et al. (2013) Biomarkers of residual disease, disseminated tumor cells, and metastases in the MMTV-PyMT breast cancer model. PLoS One 8: e58183. doi:10.1371/journal.pone.0058183.
-
(2013)
PLoS One
, vol.8
, pp. e58183
-
-
Franci, C.1
Zhou, J.2
Jiang, Z.3
Modrusan, Z.4
Good, Z.5
-
28
-
-
79961238388
-
Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials
-
doi:10.1136/bmj.d4002
-
Sterne JA, Sutton AJ, Ioannidis JP, Terrin N, Jones DR, et al. (2011) Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ 343: d4002. doi:10.1136/bmj.d4002.
-
(2011)
BMJ
, vol.343
, pp. d4002
-
-
Sterne, J.A.1
Sutton, A.J.2
Ioannidis, J.P.3
Terrin, N.4
Jones, D.R.5
-
29
-
-
5444235033
-
Role of adjuvant chemotherapy in patients with resected non-small-cell lung cancer: Reappraisal with a meta-analysis of randomized controlled trials
-
PMID: 15326194
-
Hotta K, Matsuo K, Ueoka H, Kiura K, Tabata M, et al. (2004) Role of adjuvant chemotherapy in patients with resected non-small-cell lung cancer: reappraisal with a meta-analysis of randomized controlled trials. J Clin Oncol 22: 3860-3867. PMID: 15326194.
-
(2004)
J Clin Oncol
, vol.22
, pp. 3860-3867
-
-
Hotta, K.1
Matsuo, K.2
Ueoka, H.3
Kiura, K.4
Tabata, M.5
-
30
-
-
70349443680
-
Ethnic differences and functional analysis of MET mutations in lung cancer
-
doi:10.1158/1078-0432.CCR-09-0070
-
Krishnaswamy S, Kanteti R, Duke-Cohan JS, Loganathan S, Liu W, et al. (2009) Ethnic differences and functional analysis of MET mutations in lung cancer. Clin Cancer Res 15: 5714-5723. doi:10.1158/1078-0432.CCR-09-0070.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5714-5723
-
-
Krishnaswamy, S.1
Kanteti, R.2
Duke-Cohan, J.S.3
Loganathan, S.4
Liu, W.5
-
31
-
-
84865506979
-
Rationale and design of MARQUEE: A phase III, randomized, double-blind study of tivantinib plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, nonsquamous, non-smallcell lung cancer
-
doi:10.1016/j.cllc.2012.01.003
-
Scagliotti GV, Novello S, Schiller JH, Hirsh V, Sequist LV, et al. (2012) Rationale and design of MARQUEE: a phase III, randomized, double-blind study of tivantinib plus erlotinib versus placebo plus erlotinib in previously treated patients with locally advanced or metastatic, nonsquamous, non-smallcell lung cancer. Clin Lung Cancer 13: 391-395. doi:10.1016/j.cllc.2012.01.003.
-
(2012)
Clin Lung Cancer
, vol.13
, pp. 391-395
-
-
Scagliotti, G.V.1
Novello, S.2
Schiller, J.H.3
Hirsh, V.4
Sequist, L.V.5
-
32
-
-
84899122597
-
-
2013; Amsterdam, Netherlands
-
Scagliotti G, Novello S, Ramlau R, Favaretto A, Barlesi F, et al. (2013) MARQUEE: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Tivantinib (ARQ 197) Plus Erlotinib Versus Placebo Plus Erlotinib in Previously Treated Patients With Locally Advanced or Metastatic, Non-Squamous, Non-Small-Cell Lung Cancer (NSCLC); 2013; Amsterdam, Netherlands.
-
(2013)
MARQUEE: A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Tivantinib (ARQ 197) Plus Erlotinib Versus Placebo Plus Erlotinib in Previously Treated Patients with Locally Advanced or Metastatic, Non-Squamous, Non-Small-Cell Lung Cancer (NSCLC)
-
-
Scagliotti, G.1
Novello, S.2
Ramlau, R.3
Favaretto, A.4
Barlesi, F.5
-
33
-
-
84867526394
-
Treatment rationale study design for the metlung trial: A randomized, double-blind phase iii study of onartuzumab (metmab) in combination with erlotinib versus erlotinib alone in patients who have received standard chemotherapy for stage IIIB or IV met-positive non-small-cell lung cancer
-
doi:10.1016/j.cllc.2012.05.009
-
Spigel DR, Edelman MJ, Mok T, O'Byrne K, Paz-Ares L, et al. (2012) Treatment Rationale Study Design for the MetLung Trial: A Randomized, Double-Blind Phase III Study of Onartuzumab (MetMAb) in Combination With Erlotinib Versus Erlotinib Alone in Patients Who Have Received Standard Chemotherapy for Stage IIIB or IV Met-Positive Non-Small-Cell Lung Cancer. Clin Lung Cancer 13: 500-504. doi:10.1016/j.cllc.2012.05.009.
-
(2012)
Clin Lung Cancer
, vol.13
, pp. 500-504
-
-
Spigel, D.R.1
Edelman, M.J.2
Mok, T.3
O'byrne, K.4
Paz-Ares, L.5
-
34
-
-
84902811306
-
Efficacy and safety of crizotinib in patients with advanced c-MET-amplified non-small cell lung cancer (NSCLC)
-
abstr 8001
-
Camidge D, Ou S, Shapiro G, Otterson G, Villaruz L, et al. (2014) Efficacy and safety of crizotinib in patients with advanced c-MET-amplified non-small cell lung cancer (NSCLC). J Clin Oncol 32: 5s, 2014 (suppl; abstr 8001).
-
(2014)
J Clin Oncol 32: 5s
, vol.2014
-
-
Camidge, D.1
Ou, S.2
Shapiro, G.3
Otterson, G.4
Villaruz, L.5
|