Regulation of yersinia protein kinase A (YpkA) Kinase activity by Multisite autophosphorylation and identification of an n-terminal substrate-binding domain in YpkA

Journal of Biological Chemistry

Volumn 289, Issue 38, 2014, Pages 26167-26177

  Pha, Khavong ^a   Wright, Matthew E ^a   Barr, Tasha M ^a   Eigenheer, Richard A ^a   Navarro, Lorena ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; PROTEINS;

AUTOPHOSPHORYLATION; BACTERIAL EFFECTOR; CATALYTIC MECHANISMS; INFECTIOUS DISEASE; N-TERMINAL DOMAINS; PROTEIN KINASE A; SUBSTRATE BINDING; SUBSTRATE-BINDING DOMAINS;

ENZYMES;

ALANINE; BACTERIAL PROTEIN; PROTEIN SERINE KINASE; SERINE; UNCLASSIFIED DRUG; YERSINIA PROTEIN KINASE A; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; PROTEIN BINDING; PROTEIN SERINE THREONINE KINASE; YPKA PROTEIN, YERSINIA;

AMINO ACID ANALYSIS; AMINO TERMINAL SEQUENCE; ARTICLE; AUTOPHOSPHORYLATION; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LOCALIZATION; ENZYME SUBSTRATE; GENE MUTATION; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; NONHUMAN; POINT MUTATION; PROTEIN BINDING; PROTEIN DOMAIN; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; TANDEM MASS SPECTROMETRY; YERSINIA; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; HEK293 CELL LINE; HOST PATHOGEN INTERACTION; METABOLISM; PHOSPHORYLATION; PROTEIN PROCESSING; YERSINIA ENTEROCOLITICA;

BACTERIAL PROTEINS; CATALYTIC DOMAIN; GTP-BINDING PROTEIN ALPHA SUBUNITS, GQ-G11; HEK293 CELLS; HOST-PATHOGEN INTERACTIONS; HUMANS; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; YERSINIA ENTEROCOLITICA;

EID: 84907205623     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.601153     Document Type: Article

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