Association between urinary 6-sulfatoxymelatonin excretion and arterial stiffness in the general elderly population: The HEIJO-KYO cohort

Journal of Clinical Endocrinology and Metabolism

Volumn 99, Issue 9, 2014, Pages 3233-3239

  Obayashi, Kenji ^a   Saeki, Keigo ^a   Kurumatani, Norio ^a  

^a NARA MEDICAL UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

6 HYDROXYMELATONIN O SULFATE; MELATONIN; 6-SULFATOXYMELATONIN; BIOLOGICAL MARKER;

AGE; AGED; ARTERIAL STIFFNESS; ARTICLE; ATHEROSCLEROSIS; BODY MASS; CARDIOANKLE VASCULAR INDEX; CARDIOVASCULAR PARAMETERS; CIRCADIAN RHYTHM; CROSS-SECTIONAL STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DYSLIPIDEMIA; FEMALE; GLOMERULUS FILTRATION RATE; HORMONE RELEASE; HORMONE URINE LEVEL; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PHYSICAL ACTIVITY; SEX DIFFERENCE; SLEEP TIME; SMOKING; URINARY 6 SULFATOXYMELATONIN EXCRETION; AGING; ANALOGS AND DERIVATIVES; ANKLE BRACHIAL INDEX; METABOLISM; MIDDLE AGED; MULTIVARIATE ANALYSIS; PHYSIOLOGY; PREVALENCE; RISK FACTOR; STATISTICAL MODEL; URINE; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AGING; ANKLE BRACHIAL INDEX; ATHEROSCLEROSIS; BIOLOGICAL MARKERS; BODY MASS INDEX; CIRCADIAN RHYTHM; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; LOGISTIC MODELS; MALE; MELATONIN; MIDDLE AGED; MULTIVARIATE ANALYSIS; PREVALENCE; RISK FACTORS; VASCULAR STIFFNESS;

EID: 84907190429     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2014-1262     Document Type: Article

References (43)

1. Ross R. Atherosclerosis-An inflammatory disease. N Engl J Med. 1999; 340: 115-126.
2. Oliver JJ, Webb DJ. Noninvasive assessment of arterial stiffness and risk of atherosclerotic events. Arterioscler Thromb Vasc Biol. 2003; 23: 554-566.
3. Mattace-Raso FU, van der Cammen TJ, Hofman A, et al. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation. 2006; 113: 657-663.
4. Vlachopoulos C, Aznaouridis K, Stefanadis C. Prediction of cardiovascular events and all-cause mortality with arterial stiffness: a systematic review and meta-Analysis. J Am Coll Cardiol. 2010; 55: 1318-1327.
5. Nye ER. The effect of blood pressure alteration on the pulse wave velocity. Br Heart J. 1964; 26: 261-265.
6. Shirai K, Utino J, Otsuka K, Takata M. A novel blood pressureindependent arterial wall stiffness parameter; cardio-Ankle vascular index (CAVI). J Atheroscler Thromb. 2006; 13: 101-107.
7. Shirai K, Hiruta N, Song M, et al. Cardio-Ankle vascular index (CAVI) as a novel indicator of arterial stiffness: theory, evidence and perspectives. J Atheroscler Thromb. 2011; 18: 924-938.
8. Takaki A, Ogawa H, Wakeyama T, et al. Cardio-Ankle vascular index is superior to brachial-Ankle pulse wave velocity as an index of arterial stiffness. Hypertens Res. 2008; 31: 1347-1355.
9. Brzezinski A. Melatonin in humans. N Engl J Med. 1997; 336: 186-195.
10. Yamasaki F, Schwartz JE, Gerber LM, Warren K, Pickering TG. Impact of shift work and race/ethnicity on the diurnal rhythm of blood pressure and catecholamines. Hypertension. 1998; 32: 417-423.
11. Karlsson B, Knutsson A, Lindahl B. Is there an association between shift work and having a metabolic syndrome? Results from a population based study of 27 485 people. Occup Environ Med. 2001; 58: 747-752.
12. Pan A, Schernhammer ES, Sun Q, Hu FB. Rotating night shift work and risk of type 2 diabetes: two prospective cohort studies in women. PLoS Med. 2011; 8: e1001141.
13. Viswambharan H, Carvas JM, Antic V, et al. Mutation of the circadian clock gene Per2 alters vascular endothelial function. Circulation. 2007; 115: 2188-2195.
14. Anea CB, Zhang M, Stepp DW, et al. Vascular disease in mice with a dysfunctional circadian clock. Circulation. 2009; 119: 1510-1517.
15. Anea CB, Cheng B, Sharma S, et al. Increased superoxide and endothelialNOsynthase uncoupling in blood vessels of Bmal1-knockout mice. Circ Res. 2012; 111: 1157-1165.
16. Koziróg M, Poliwczak AR, Duchnowicz P, Koter-Michalak M, Sikora J, Broncel M. Melatonin treatment improves blood pressure, lipid profile, and parameters of oxidative stress in patients with metabolic syndrome. J Pineal Res. 2011; 50: 261-266.
17. Favero G, Rodella LF, Reiter RJ, Rezzani R. Melatonin and its atheroprotective effects: a review. Mol Cell Endocrinol. 2014; 382: 926-937.
18. Baskett JJ, Cockrem JF, Antunovich TA. Sulphatoxymelatonin excretion in older people: relationship to plasma melatonin and renal function. J Pineal Res. 1998; 24: 58-61.
19. Obayashi K, Saeki K, Iwamoto J, et al. Positive effect of daylight exposure on nocturnal urinary melatonin excretion in the elderly: a cross-sectional analysis of the HEIJO-KYO study. J Clin Endocrinol Metab. 2012; 97: 4166-4173.
20. Fukuda Denshi Co Ltd. The manufacturer's instruction of CAVI. http://www.fukuda.co.jp/english/products/special-features/vasera/cavi.html. Accessed January 25, 2014.
21. Buysse DJ, ReynoldsCF3rd,MonkTH,BermanSR, Kupfer DJ. The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research. Psychiatry Res. 1989; 28: 193-213.
22. Mehra R, Stone KL, Ancoli-Israel S, Litwack-Harrison S, Ensrud KE, Redline S. Interpreting wrist actigraphic indices of sleep in epidemiologic studies of the elderly: the Study of Osteoporotic Fractures. Sleep. 2008; 31: 1569-1576.
23. Zhdanova IV, Wurtman RJ, Regan MM, Taylor JA, Shi JP, Leclair OU. Melatonin treatment for age-related insomnia. J Clin Endocrinol Metab. 2001; 86: 4727-4730.
24. Spiegel K, Tasali E, Penev P, Van Cauter E. Sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med. 2004; 141: 846-850.
25. Gangwisch JE. Epidemiological evidence for the links between sleep, circadian rhythms and metabolism. Obes Rev. 2009; 10: 37-45.
26. Scheer FA, Hilton MF, Mantzoros CS, Shea SA. Adverse metabolic and cardiovascular consequences of circadian misalignment. Proc Natl Acad Sci USA. 2009; 106: 4453-4458.
27. McMullan CJ, Schernhammer ES, Rimm EB, Hu FB, Forman JP. Melatonin secretion and the incidence of type 2 diabetes. JAMA. 2013; 309: 1388-1396.
28. Drew JE, Barrett P, Mercer JG, et al. Localization of the melatoninrelated receptor in the rodent brain and peripheral tissues. J Neuroendocrinol. 2001; 13: 453-458.
29. Ekmekcioglu C, Thalhammer T, Humpeler S, et al. The melatonin receptor subtype MT2 is present in the human cardiovascular system. J Pineal Res. 2003; 35: 40-44.
30. Pogan L, Bissonnette P, Parent L, Sauvé R. The effects of melatonin on Ca2-homeostasis in endothelial cells. J Pineal Res. 2002; 33: 37-47.
31. Garg UC, Hassid A. Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells. J Clin Invest. 1989; 83: 1774-1777.
32. von der Leyen HE, Gibbons GH, Morishita R, et al. Gene therapy inhibiting neointimal vascular lesion: in vivo transfer of endothelial cell nitric oxide synthase gene. Proc Natl Acad Sci USA. 1995; 92: 1137-1141.
33. Scheer FA, Van Montfrans GA, van Someren EJ, Mairuhu G, Buijs RM. Daily nighttime melatonin reduces blood pressure in male patients with essential hypertension. Hypertension. 2004; 43: 192-197.
34. Grossman E, Laudon M, Yalcin R, et al. Melatonin reduces night blood pressure in patients with nocturnal hypertension. Am J Med. 2006; 119: 898-902.
35. Obayashi K, Saeki K, Iwamoto J, et al. Nocturnal urinary melatonin excretion is associated with non-dipper pattern in elderly hypertensives. Hypertens Res. 2013; 36: 736-740.
36. Tengattini S, Reiter RJ, Tan DX, Terron MP, Rodella LF, Rezzani R. Cardiovascular diseases: protective effects of melatonin. J Pineal Res. 2008; 44: 16-25.
37. Schernhammer ES, Kroenke CH, DowsettM,Folkerd E, Hankinson SE. Urinary 6-sulfatoxymelatonin levels and their correlations with lifestyle factors and steroid hormone levels. J Pineal Res. 2006; 40: 116-124.
38. Forman JP, Curhan GC, Schernhammer ES. Urinary melatonin and risk of incident hypertension among young women. J Hypertens. 2010; 28: 446-451.
39. CorradaMM,Kawas CH, Mozaffar F, Paganini-Hill A. Association of body mass index and weight change with all-cause mortality in the elderly. Am J Epidemiol. 2006; 163: 938-949.
40. Diehr P, Bild DE, Harris TB, Duxbury A, Siscovick D, Rossi M. Body mass index and mortality in nonsmoking older adults: the Cardiovascular Health Study. Am J Public Health. 1998; 88: 623-629.
41. Cornoni-Huntley JC, Harris TB, Everett DF, et al. An overview of body weight of older persons, including the impact on mortality. The National Health and Nutrition Examination Survey I-Epidemiologic Follow-up Study. J Clin Epidemiol. 1991; 8: 743-753.
42. Romero-Corral A, Montori VM, Somers VK, et al. Association of bodyweight with total mortality and with cardiovascular events in coronary artery disease: a systematic review of cohort studies. Lancet. 2006; 368: 666-678.
43. The National Health and Nutrition Survey Japan. 2010. http://www.mhlw.go.jp/bunya/kenkou/eiyou/h22-houkoku.html (Japanese). Accessed January 25, 2014.