The effects of melatonin on Ca2+ homeostasis in endothelial cells

Journal of Pineal Research

Volumn 33, Issue 1, 2002, Pages 37-47

  Pogan, L ^a   Bissonnette, P ^a   Parent, L ^a   Sauve R ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Capacitative Ca2+ entry; Endothelium; Free radicals; Fura 2; Hypertension; InsP3; Melatonin

Indexed keywords

ADENOSINE TRIPHOSPHATE; BRADYKININ; CALCIUM ION; FREE RADICAL; FURA 2; MELATONIN; SUPEROXIDE; CALCIUM; CELL RECEPTOR; CELL SURFACE RECEPTOR; INOSITOL PHOSPHATE; MELATONIN RECEPTOR; SCAVENGER;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; ARTICLE; BINDING SITE; CALCIUM HOMEOSTASIS; CALCIUM MOBILIZATION; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL CULTURE; CELL TYPE; CONTROLLED STUDY; DRUG EFFECT; ENDOTHELIUM CELL; INCUBATION TIME; MALE; NONHUMAN; RAT; ANIMAL; AORTA; CATTLE; CYTOLOGY; HOMEOSTASIS; HYPERTENSION; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; REFERENCE VALUE; SPONTANEOUSLY HYPERTENSIVE RAT; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM;

ADENOSINE TRIPHOSPHATE; ANIMAL; AORTA; BINDING SITES; BRADYKININ; CALCIUM; CATTLE; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; FREE RADICAL SCAVENGERS; HOMEOSTASIS; HYPERTENSION; INOSITOL PHOSPHATES; MALE; MELATONIN; OXIDATIVE STRESS; RATS; RATS, INBRED SHR; RATS, SPRAGUE-DAWLEY; RECEPTORS, CELL SURFACE; RECEPTORS, CYTOPLASMIC AND NUCLEAR; REFERENCE VALUES; SUPEROXIDES; SUPPORT, NON-U.S. GOV'T; ANIMALS; RECEPTORS, MELATONIN;

EID: 0035992615     PISSN: 07423098     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-079X.2002.01890.x     Document Type: Article

References (50)

1. Melatonin-induced relaxation of rat aorta: Interaction with adrenergic agonists
2. The inhibitory action of melatonin on the contractile response to 5-hydroxytryptamine in various isolated vascular smooth muscles
3. Melatonin directly constricts rat cerebral arteries through modulation of potassium channels
4. Melatonin receptors mediate contraction of a rat cerebral artery
5. Evidence for direct vasoconstrictor activity of melatonin in 'pressurized' segments of isolated caudal artery from juvenile rats
6. Melatonin receptors mediate potentiation of contractile responses to adrenergic nerve stimulation in rat caudal artery
7. Antihypertensive action of melatonin in the spontaneously hypertensive rat
8. Hypotensive effect of melatonin in essential hypertension
9. Nitric oxide and cardiovascular control
10. 2+ and nitric oxide in bradykinin-stimulated vascular endothelial cells
11. Production of endothelium derived relaxant factor is dependent on oxidative phosphorylation and extracellular calcium
12. Ion channels and their functional role in vascular endothelium
13. Abnormal regulation of cytosolic free calcium in vascular endothelial cells from spontaneously hypertensive rats
14. 2+ indicators with greatly improved fluorescence properties
15. + channel in cultured bovine aortic endothelial cells
16. Enhanced inhibition by melatonin of alpha-adrenoceptor-induced aortic contraction and inositol phosphate production in vascular smooth cells from spontaneously hypertensive rats
17. 2+ signalling in vascular endothelial cells from spontaneously hypertensive rats: Role of free radicals
18. Endothelial dysfunction of resistance arteries of spontaneously hypertensive rats
19. Role of superoxide in the depressed nitric oxide production by the endothelium of genetically hypertensive rats
20. Comparative study on free radical injury in the endothelium of SHR and WKY aorta
21. Expression of melatonin receptors in arteries involved in thermoregulation
22. Pineal gland hormone melatonin binds and activates an orphan of the nuclear receptor superfamily
23. Melatonin receptors: Are there multiple subtypes?
24. Molecular pharmacology and function of melatonin receptor subtypes
25. Melatonin and cardiovascular function
26. Tetrahydrobiopterin and endothelial function
27. Effect of oxidant stress on calcium signaling in vascular endothelial cells
28. Antioxidant role of melatonin in lipid peroxidation of human LDL
29. Antioxidant properties of melatonin - An emerging mystery
30. Effects of melatonin on lipid peroxidation induced by oxygen radicals
31. Pharmacological actions of melatonin in oxygen radical pathophysiology
32. Melatonin: A potent endogenous hydroxyl radical scavenger
33. Melatonin protects against the free radical-induced impairment of nitric oxide production in the human umbilical artery
34. Melatonin stimulates brain glutathione peroxidase activity
35. Melatonin prevents ischemia reperfusion injury in hamster cheek pouch microcirculation
36. Functional aspects of the pineal hormone melatonin in combating cell and tissue damage induced by free radicals
37. Scavenging of reactive oxygen species by melatonin
38. Characterization of the bradykinin-stimulated calcium influx pathway of cultured vascular endothelial Cells
39. 2+ mobilization and influx through voltage-regulated channels
40. Apamin blocks the direct relaxant effect of melatonin on rat ileal smooth muscle
41. +-channels attenuated melatonin-induced relaxation of serotonin-contracted rat gastric fundus
42. Acetylcholine induces Ca-dependent K currents in rabbit endothelial cells
43. + channel contributes to bradykinin-induced stimulation of nitric oxide synthesis in pig aortic endothelial cells
44. Calcium-activated potassium channels in the endothelium of intact rat aorta
45. 2+) channel of intermediate conductance in bovine aortic endothelial cells
46. A role for the actin cytoskeleton in the initiation and maintenance of store-mediated calcium entry in human platelets
47. Effects of melatonin on microtubule assembly depend on hormone concentration: Role of melatonin as a calmodulin antagonist
48. 2+-selective channel in vascular endothelium
49. Binding of 3H-melatonin to calmodulin
50. Membrane-bound calmodulin in Xenopus laevis oocytes as a novel binding site for melatonin