Rosa26 locus supports tissue-specific promoter driving transgene expression specifically in pig

PLoS ONE

Volumn 9, Issue 9, 2014, Pages

  Kong, Qingran ^a   Hai, Tang ^b   Ma, Jing ^a   Huang, Tianqing ^a   Jiang, Dandan ^a   Xie, Bingteng ^a   Wu, Meiling ^a   Wang, Jiaqiang ^a   Song, Yuran ^b,c   Wang, Ying ^b   He, Yilong ^a   Sun, Jialu ^a   Hu, Kui ^a   Guo, Runfa ^a   Wang, Liu ^b   Zhou, Qi ^b   Mu, Yanshuang ^a   Liu, Zhonghua ^a  

^a NORTHEAST AGRICULTURAL UNIVERSITY   (China)

^b INSTITUTE OF ZOOLOGY   (China)

^c UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ELONGATION FACTOR 1ALPHA; FOLLISTATIN; GREEN FLUORESCENT PROTEIN; MYOSTATIN; UNTRANSLATED RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; EMBRYO; GENE; GENE EXPRESSION; GENE LOCUS; GENE SEQUENCE; GENE TARGETING; GENE TRANSFER; HOMOLOGOUS RECOMBINATION; MOLECULAR CLONING; MUSCLE; NONHUMAN; PROMOTER REGION; ROSA26 GENE; SWINE; TISSUE SPECIFICITY; TRANSGENE; ANIMAL; ANTIBODY SPECIFICITY; BIOSYNTHESIS; CELL CULTURE; GENETICS; METABOLISM; MINIPIG; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PIG; REPORTER GENE; SKELETAL MUSCLE; TRANSCRIPTION INITIATION; TRANSGENIC ANIMAL;

SUIDAE;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; CELLS, CULTURED; GENE EXPRESSION; GENES, REPORTER; GENETIC LOCI; GREEN FLUORESCENT PROTEINS; MOLECULAR SEQUENCE DATA; MUSCLE, SKELETAL; ORGAN SPECIFICITY; PROMOTER REGIONS, GENETIC; RNA, UNTRANSLATED; SUS SCROFA; SWINE; SWINE, MINIATURE; TRANSCRIPTIONAL ACTIVATION;

EID: 84907190377     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0107945     Document Type: Article

References (34)

1. Whyte JJ, Prather RS (2011) Genetic modifications of pigs for medicine and agriculture. Mol Reprod Dev 78: 879-891.
2. Lai L, Kang JX, Li R, Wang J, Witt WT, et al. (2006) Generation of cloned transgenic pigs rich in omega-3 fatty acids. Nat Biotechnol 24: 435-436.
3. Eszterhas SK, Bouhassira EE, Martin DI, Fiering S (2002) Transcriptional interference by independently regulated genes occurs in any relative arrangement of the genes and is influenced by chromosomal integration position. Mol Cell Biol 22: 469-479.
4. Chiaromonte F, Miller W, Bouhassira EE (2003) Gene length and proximity to neighbors affect genome-wide expression levels. Genome Res 13: 2602-2608.
5. Xin J, Yang H, Fan N, Zhao B, Ouyang Z, et al. (2013) Highly efficient generation of GGTA1 biallelic knockout inbred mini-pigs with TALENs. PloS one 8: e84250.
6. Hai T, Teng F, Guo R, Li W, Zhou Q (2014) One-step generation of knockout pigs by zygote injection of CRISPR/Cas system. Cell Res 24: 372-375.
7. Wu H, Zhang Y (2011) Mechanisms and functions of Tet protein-mediated 5-methylcytosine oxidation. Genes Dev 25: 2436-2452.
8. Carlson DF, Tan W, Lillico SG, Stverakova D, Proudfoot C, et al. (2012) Efficient TALEN-mediated gene knockout in livestock. Proc Natl Acad Sci U S A 109: 17382-17387.
9. Olsen PA, Gelazauskaite M, Randol M, Krauss S (2010) Analysis of illegitimate genomic integration mediated by zinc-finger nucleases: implications for specificity of targeted gene correction. BMC molecular biology 11: 35.
10. Cornu TI, Thibodeau-Beganny S, Guhl E, Alwin S, Eichtinger M, et al. (2008) DNA-binding specificity is a major determinant of the activity and toxicity of zinc-finger nucleases. Molecular therapy: the journal of the American Society of Gene Therapy 16: 352-358.
11. Cornu TI, Cathomen T (2010) Quantification of zinc finger nuclease-associated toxicity. Methods Mol Biol 649: 237-245.
12. Pattanayak V, Ramirez CL, Joung JK, Liu DR (2011) Revealing off-target cleavage specificities of zinc-finger nucleases by in vitro selection. Nature methods 8: 765-770.
13. Gupta A, Meng X, Zhu LJ, Lawson ND, Wolfe SA (2011) Zinc finger proteindependent and-independent contributions to the in vivo off-target activity of zinc finger nucleases. Nucleic Acids Res 39: 381-392.
14. Radecke S, Radecke F, Cathomen T, Schwarz K (2010) Zinc-finger nucleaseinduced gene repair with oligodeoxynucleotides: wanted and unwanted target locus modifications. Molecular therapy: the journal of the American Society of Gene Therapy 18: 743-753.
15. Owens JB, Mauro D, Stoytchev I, Bhakta MS, Kim MS, et al. (2013) Transcription activator like effector (TALE)-directed piggyBac transposition in human cells. Nucleic Acids Res 41: 9197-9207.
16. Capecchi MR (1989) Altering the genome by homologous recombination. Science 244: 1288-1292.
17. Capecchi MR (2000) How close are we to implementing gene targeting in animals other than the mouse? Proc Natl Acad Sci U S A 97: 956-957.
18. Friedrich G, Soriano P (1991) Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice. Genes Dev 5: 1513-1523.
19. Srinivas S, Watanabe T, Lin CS, William CM, Tanabe Y, et al. (2001) Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC developmental biology 1: 4.
20. Nyabi O, Naessens M, Haigh K, Gembarska A, Goossens S, et al. (2009) Efficient mouse transgenesis using Gateway-compatible ROSA26 locus targeting vectors and F1 hybrid ES cells. Nucleic Acids Res 37: e55.
21. Irion S, Luche H, Gadue P, Fehling HJ, Kennedy M, et al. (2007) Identification and targeting of the ROSA26 locus in human embryonic stem cells. Nat Biotechnol 25: 1477-1482.
22. Kobayashi T, Kato-Itoh M, Yamaguchi T, Tamura C, Sanbo M, et al. (2012) Identification of rat Rosa26 locus enables generation of knock-in rat lines ubiquitously expressing tdTomato. Stem cells and development 21: 2981-2986.
23. Li X, Yang Y, Bu L, Guo X, Tang C, et al. (2014) Rosa26-targeted swine models for stable gene over-expression and Cre-mediated lineage tracing. Cell Res.
24. Wang P, Wang SM, Hsieh CJ, Chien CL (2006) Neural expression of alphainternexin promoter in vitro and in vivo. J Cell Biochem 97: 275-287.
25. Vandenbon A, Nakai K (2010) Modeling tissue-specific structural patterns in human and mouse promoters. Nucleic Acids Res 38: 17-25.
26. Rao P, Monks DA (2009) A tetracycline-inducible and skeletal muscle-specific Cre recombinase transgenic mouse. Developmental neurobiology 69: 401-406.
27. Schumacher A, Koetsier PA, Hertz J, Doerfler W (2000) Epigenetic and genotype-specific effects on the stability of de novo imposed methylation patterns in transgenic mice. J Biol Chem 275: 37915-37921.
28. Tchorz JS, Suply T, Ksiazek I, Giachino C, Cloetta D, et al. (2012) A modified RMCE-compatible Rosa26 locus for the expression of transgenes from exogenous promoters. PloS one 7: e30011.
29. Chen C, Krohn J, Bhattacharya S, Davies B (2011) A comparison of exogenous promoter activity at the ROSA26 locus using a WiC31 integrase mediated cassette exchange approach in mouse ES cells. PloS one 6: e23376.
30. Gross JB, Hanken J, Oglesby E, Marsh-Armstrong N (2006) Use of a ROSA26: GFP transgenic line for long-term Xenopus fate-mapping studies. J Anat 209: 401-413.
31. Burket CT, Montgomery JE, Thummel R, Kassen SC, LaFave MC, et al. (2008) Generation and characterization of transgenic zebrafish lines using different ubiquitous promoters. Transgenic Res 17: 265-279.
32. Spiller MP, Kambadur R, Jeanplong F, Thomas M, Martyn JK, et al. (2002) The myostatin gene is a downstream target gene of basic helix-loop-helix transcription factor MyoD. Mol Cell Biol 22: 7066-7082.
33. Lee SJ, McPherron AC (2001) Regulation of myostatin activity and muscle growth. Proc Natl Acad Sci U S A 98: 9306-9311.
34. Li D, Da L, Tang H, Li T, Zhao M (2008) CpG methylation plays a vital role in determining tissue-and cell-specific expression of the human cell-death-inducing DFF45-like effector A gene through the regulation of Sp1/Sp3 binding. Nucleic Acids Res 36: 330-341.