Enhanced gene delivery in porcine vasculature tissue following incorporation of adeno-associated virus nanoparticles into porous silicon microparticles

Journal of Controlled Release

Volumn 194, Issue , 2014, Pages 113-121

  McConnell, Kellie I ^a   Rhudy, Jessica ^a   Yokoi, Kenji ^a   Gu, Jianhua ^a   Mack, Aaron ^a   Suh, Junghae ^b   La Francesca, Saverio ^c   Sakamoto, Jason ^a   Serda, Rita E ^a,d  

^a HOUSTON METHODIST RESEARCH INSTITUTE   (United States)

^b Rice University   (United States)

^c HOUSTON METHODIST HOSPITAL   (United States)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Adeno associated virus; Endothelium; Ex vivo perfusion; Inflammation; Lung; Mesoporous silicon

Indexed keywords

ADENO-ASSOCIATED VIRUS; ENDOTHELIUM; EX-VIVO; INFLAMMATION; LUNG; MESOPOROUS SILICON;

ANTIINFLAMMATORY AGENT; GREEN FLUORESCENT PROTEIN; NANOPARTICLE; PARVOVIRUS VECTOR; SILICON;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE DELIVERY SYSTEM; GENE EXPRESSION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; HYDROPHOBICITY; LUNG TRANSPLANTATION; NONHUMAN; PARTICLE SIZE; REPERFUSION INJURY; REPORTER GENE; SWINE; VASCULAR ENDOTHELIUM; VIRUS PARTICLE; ZETA POTENTIAL; ANIMAL; BLOOD VESSEL; CHEMISTRY; CYTOLOGY; DEPENDOPARVOVIRUS; DRUG EFFECTS; ENDOTHELIUM CELL; GENE TRANSFER; IMMUNOLOGY; LUNG; METABOLISM; PIG; VEIN; VIROLOGY;

ANIMALS; BLOOD VESSELS; DEPENDOVIRUS; ENDOTHELIAL CELLS; GENE EXPRESSION; GENE TRANSFER TECHNIQUES; HUMANS; LUNG; NANOPARTICLES; PARTICLE SIZE; SILICON; SWINE; VEINS;

EID: 84907189306     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2014.08.020     Document Type: Article

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