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Volumn 42, Issue 3, 2014, Pages 823-831

Effects of supplementation with omega-3 fatty acids on oxidative stress and inflammation in patients with Alzheimer's disease: The OmegAD study

Author keywords

Alzheimer's disease; eicosanoids; F2 isoprostane; inflammation; lipids; omega 3 fatty acids; oxidative stress; prostaglandin F2

Indexed keywords

15 KETO DIHYDRO PROSTAGLANDIN F2 ALPHA; 8 ISOPROSTAGLANDIN F2 ALPHA; ARACHIDONIC ACID; BIOLOGICAL MARKER; DOCOSAHEXAENOIC ACID; ICOSAPENTAENOIC ACID; LINOLEIC ACID; PROSTAGLANDIN F2 ALPHA; UNCLASSIFIED DRUG; CYTOKINE; ISOPROSTANE DERIVATIVE;

EID: 84907155927     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-132042     Document Type: Article
Times cited : (59)

References (43)
  • 2
    • 84871671961 scopus 로고    scopus 로고
    • A commentary on studies presenting projections of the future prevalence of dementia
    • Norton S, Matthews FE, Brayne C (2013) A commentary on studies presenting projections of the future prevalence of dementia. BMC Public Health 13, 1.
    • (2013) BMC Public Health , vol.13 , pp. 1
    • Norton, S.1    Matthews, F.E.2    Brayne, C.3
  • 4
    • 84875655895 scopus 로고    scopus 로고
    • Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature
    • Wyss-Coray T, Rogers J (2012) Inflammation in Alzheimer disease-a brief review of the basic science and clinical literature. Cold Spring Harb Perspect Med 2, a006346.
    • (2012) Cold Spring Harb Perspect Med , vol.2 , pp. a006346
    • Wyss-Coray, T.1    Rogers, J.2
  • 5
    • 0032088451 scopus 로고    scopus 로고
    • Is oxidative damage central to the pathogenesis of Alzheimer disease?
    • Perry G, Smith MA (1998) Is oxidative damage central to the pathogenesis of Alzheimer disease? Acta Neurol Belg 98, 175-179.
    • (1998) Acta Neurol Belg , vol.98 , pp. 175-179
    • Perry, G.1    Smith, M.A.2
  • 6
    • 51749090447 scopus 로고    scopus 로고
    • F2-isoprostanes in human health and diseases: From molecular mechanisms to clinical implications
    • Basu S (2008) F2-isoprostanes in human health and diseases: From molecular mechanisms to clinical implications. Antioxid Redox Signal 10, 1405-1434.
    • (2008) Antioxid Redox Signal , vol.10 , pp. 1405-1434
    • Basu, S.1
  • 7
    • 0346494715 scopus 로고    scopus 로고
    • Isomer-specific effects of conjugated linoleic acid on lipid peroxidation in humans: Regulation by alpha-tocopherol and cyclooxygenase-2 inhibitor
    • Smedman A, Vessby B, Basu S (2004) Isomer-specific effects of conjugated linoleic acid on lipid peroxidation in humans: Regulation by alpha-tocopherol and cyclooxygenase-2 inhibitor. Clin Sci (Lond) 106, 67-73.
    • (2004) Clin Sci (Lond) , vol.106 , pp. 67-73
    • Smedman, A.1    Vessby, B.2    Basu, S.3
  • 8
    • 72849109858 scopus 로고    scopus 로고
    • NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease
    • Varvel NH, Bhaskar K, Kounnas MZ, Wagner SL, Yang Y, Lamb BT, Herrup K (2009) NSAIDs prevent, but do not reverse, neuronal cell cycle reentry in a mouse model of Alzheimer disease. J Clin Invest 119, 3692-3702.
    • (2009) J Clin Invest , vol.119 , pp. 3692-3702
    • Varvel, N.H.1    Bhaskar, K.2    Kounnas, M.Z.3    Wagner, S.L.4    Yang, Y.5    Lamb, B.T.6    Herrup, K.7
  • 12
    • 16244416174 scopus 로고    scopus 로고
    • A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model
    • Lim GP, Calon F, Morihara T, Yang F, Teter B, Ubeda O, Salem N, Jr., Frautschy SA, Cole GM (2005) A diet enriched with the omega-3 fatty acid docosahexaenoic acid reduces amyloid burden in an aged Alzheimer mouse model. J Neurosci 25, 3032-3040.
    • (2005) J Neurosci , vol.25 , pp. 3032-3040
    • Lim, G.P.1    Calon, F.2    Morihara, T.3    Yang, F.4    Teter, B.5    Ubeda, O.6    Salem, N.7    Frautschy, S.A.8    Cole, G.M.9
  • 13
    • 0016823810 scopus 로고
    • "mini-mental state". A practical method for grading the cognitive state of patients for the clinician
    • Folstein MF, Folstein SE, McHugh PR (1975) "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12, 189-198.
    • (1975) J Psychiatr Res , vol.12 , pp. 189-198
    • Folstein, M.F.1    Folstein, S.E.2    McHugh, P.R.3
  • 14
    • 0030814418 scopus 로고    scopus 로고
    • Development of cognitive instruments for use in clinical trials of antidementia drugs: Additions to the Alzheimer's Disease Assessment Scale that broaden its scope. The Alzheimer's Disease Cooperative Study
    • Mohs RC, Knopman D, Petersen RC, Ferris SH, Ernesto C, Grundman M, Sano M, Bieliauskas L, Geldmacher D, Clark C, Thal LJ (1997) Development of cognitive instruments for use in clinical trials of antidementia drugs: Additions to the Alzheimer's Disease Assessment Scale that broaden its scope. The Alzheimer's Disease Cooperative Study. Alzheimer Dis Assoc Disord 11(Suppl 2), S13-S21.
    • (1997) Alzheimer Dis Assoc Disord , vol.11 , pp. S13-S21
    • Mohs, R.C.1    Knopman, D.2    Petersen, R.C.3    Ferris, S.H.4    Ernesto, C.5    Grundman, M.6    Sano, M.7    Bieliauskas, L.8    Geldmacher, D.9    Clark, C.10    Thal, L.J.11
  • 16
    • 0018425438 scopus 로고
    • A new depression scale designed to be sensitive to change
    • Montgomery SA, Asberg M (1979) A new depression scale designed to be sensitive to change. Br J Psychiatry 134, 382-389.
    • (1979) Br J Psychiatry , vol.134 , pp. 382-389
    • Montgomery, S.A.1    Asberg, M.2
  • 17
    • 0031595825 scopus 로고    scopus 로고
    • Radioimmunoassay of 8-iso-prostaglandin F2alpha: An index for oxidative injury via free radical catalysed lipid peroxidation
    • Basu S (1998) Radioimmunoassay of 8-iso-prostaglandin F2alpha: An index for oxidative injury via free radical catalysed lipid peroxidation. Prostaglandins Leukot Essent Fatty Acids 58, 319-325.
    • (1998) Prostaglandins Leukot Essent Fatty Acids , vol.58 , pp. 319-325
    • Basu, S.1
  • 18
    • 0031846925 scopus 로고    scopus 로고
    • Radioimmunoassay of 15-keto-13,14-dihydroprostaglandin F2alpha: An index for inflammation via cyclooxygenase catalysed lipid peroxidation
    • Basu S (1998) Radioimmunoassay of 15-keto-13,14-dihydroprostaglandin F2alpha: An index for inflammation via cyclooxygenase catalysed lipid peroxidation. Prostaglandins Leukot Essent Fatty Acids 58, 347-352.
    • (1998) Prostaglandins Leukot Essent Fatty Acids , vol.58 , pp. 347-352
    • Basu, S.1
  • 19
    • 0029035429 scopus 로고
    • Cerebrospinal fluid 'neuronal thread protein' comes from serum by passage over the blood-brain barrier
    • Blennow K, Wallin A, Chong JK (1995) Cerebrospinal fluid 'neuronal thread protein' comes from serum by passage over the blood-brain barrier. Neurodegeneration 4, 187-193.
    • (1995) Neurodegeneration , vol.4 , pp. 187-193
    • Blennow, K.1    Wallin, A.2    Chong, J.K.3
  • 21
    • 0033061647 scopus 로고    scopus 로고
    • Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: Differences between early-and late-onset Alzheimer disease and stability during the course of disease
    • Andreasen N, Hesse C, Davidsson P, Minthon L, Wallin A, Winblad B, Vanderstichele H, Vanmechelen E, Blennow K (1999) Cerebrospinal fluid beta-amyloid(1-42) in Alzheimer disease: Differences between early-and late-onset Alzheimer disease and stability during the course of disease. Arch Neurol 56, 673-680.
    • (1999) Arch Neurol , vol.56 , pp. 673-680
    • Andreasen, N.1    Hesse, C.2    Davidsson, P.3    Minthon, L.4    Wallin, A.5    Winblad, B.6    Vanderstichele, H.7    Vanmechelen, E.8    Blennow, K.9
  • 22
    • 0022347716 scopus 로고
    • Fatty acid composition of platelets and of plasma lipid esters in relation to platelet function in patients with ischaemic heart disease
    • Boberg M, Vessby B, Croon LB (1985) Fatty acid composition of platelets and of plasma lipid esters in relation to platelet function in patients with ischaemic heart disease. Atherosclerosis 58, 49-63.
    • (1985) Atherosclerosis , vol.58 , pp. 49-63
    • Boberg, M.1    Vessby, B.2    Croon, L.B.3
  • 23
    • 67349173942 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale
    • Calder PC (2009) Polyunsaturated fatty acids and inflammatory processes: New twists in an old tale. Biochimie 91, 791-795.
    • (2009) Biochimie , vol.91 , pp. 791-795
    • Calder, P.C.1
  • 24
    • 0142258704 scopus 로고    scopus 로고
    • Effect of eicosapentaenoic acid and docosahexaenoic acid on oxidative stress and inflammatory markers in treated-hypertensive type 2 diabetic subjects
    • Mori TA,Woodman RJ, BurkeV, Puddey IB, Croft KD, Beilin LJ (2003) Effect of eicosapentaenoic acid and docosahexaenoic acid on oxidative stress and inflammatory markers in treated-hypertensive type 2 diabetic subjects. Free Radic Biol Med 35, 772-781.
    • (2003) Free Radic Biol Med , vol.35 , pp. 772-781
    • Mori, T.A.1    Woodman, R.J.2    Burke, V.3    Puddey, I.B.4    Croft, K.D.5    Beilin, L.J.6
  • 26
    • 0034543797 scopus 로고    scopus 로고
    • The isoprostanes: Their quantification as an index of oxidant stress status in vivo
    • Morrow JD (2000) The isoprostanes: Their quantification as an index of oxidant stress status in vivo. Drug Metab Rev 32, 377-385.
    • (2000) Drug Metab Rev , vol.32 , pp. 377-385
    • Morrow, J.D.1
  • 27
    • 3242690571 scopus 로고    scopus 로고
    • Increased urinary F(2)-isoprostanes levels in the patients with Alzheimer's disease
    • Kim KM, Jung BH, Paeng KJ, Kim I, Chung BC (2004) Increased urinary F(2)-isoprostanes levels in the patients with Alzheimer's disease. Brain Res Bull 64, 47-51.
    • (2004) Brain Res Bull , vol.64 , pp. 47-51
    • Kim, K.M.1    Jung, B.H.2    Paeng, K.J.3    Kim, I.4    Chung, B.C.5
  • 31
    • 79952701623 scopus 로고    scopus 로고
    • Increased cerebrospinal fluid F2-isoprostanes are associated with aging and latent Alzheimer's disease as identified by biomarkers
    • Montine TJ, Peskind ER, Quinn JF, Wilson AM, Montine KS, Galasko D (2011) Increased cerebrospinal fluid F2-isoprostanes are associated with aging and latent Alzheimer's disease as identified by biomarkers. Neuromolecular Med 13, 37-43.
    • (2011) Neuromolecular Med , vol.13 , pp. 37-43
    • Montine, T.J.1    Peskind, E.R.2    Quinn, J.F.3    Wilson, A.M.4    Montine, K.S.5    Galasko, D.6
  • 32
    • 0032238783 scopus 로고    scopus 로고
    • Increased F2-isoprostanes in Alzheimer's disease: Evidence for enhanced lipid peroxidation in vivo
    • Pratico D, V MYL, Trojanowski JQ, Rokach J, Fitzgerald GA (1998) Increased F2-isoprostanes in Alzheimer's disease: Evidence for enhanced lipid peroxidation in vivo. FASEB J 12, 1777-1783.
    • (1998) FASEB J , vol.12 , pp. 1777-1783
    • Pratico, D.1    Myl, V.2    Trojanowski, J.Q.3    Rokach, J.4    Fitzgerald, G.A.5
  • 33
    • 0032557637 scopus 로고    scopus 로고
    • Metabolism of 8-iso-prostaglandin F2alpha
    • Basu S (1998) Metabolism of 8-iso-prostaglandin F2alpha. FEBS Lett 428, 32-36.
    • (1998) FEBS Lett , vol.428 , pp. 32-36
    • Basu, S.1
  • 34
    • 79960880118 scopus 로고    scopus 로고
    • Assessing the contribution of inflammation in models of Alzheimer's disease
    • Johnston H, Boutin H, Allan SM (2011) Assessing the contribution of inflammation in models of Alzheimer's disease. Biochem Soc Trans 39, 886-890.
    • (2011) Biochem Soc Trans , vol.39 , pp. 886-890
    • Johnston, H.1    Boutin, H.2    Allan, S.M.3
  • 36
    • 33646201107 scopus 로고    scopus 로고
    • TNFalpha modulation for treatment of Alzheimer's disease: A 6-month pilot study
    • Tobinick E, Gross H, Weinberger A, Cohen H (2006) TNFalpha modulation for treatment of Alzheimer's disease: A 6-month pilot study. MedGenMed 8, 25.
    • (2006) Med Gen Med , vol.8 , pp. 25
    • Tobinick, E.1    Gross, H.2    Weinberger, A.3    Cohen, H.4
  • 38
    • 0031023605 scopus 로고    scopus 로고
    • Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men
    • Kalmijn S, Feskens EJ, Launer LJ, Kromhout D (1997) Polyunsaturated fatty acids, antioxidants, and cognitive function in very old men. Am J Epidemiol 145, 33-41.
    • (1997) Am J Epidemiol , vol.145 , pp. 33-41
    • Kalmijn, S.1    Feskens, E.J.2    Launer, L.J.3    Kromhout, D.4
  • 39
    • 77951173605 scopus 로고    scopus 로고
    • Omega-3 fatty acids: Potential role in the management of early Alzheimer's disease
    • Jicha GA, Markesbery WR (2010) Omega-3 fatty acids: Potential role in the management of early Alzheimer's disease. Clin Interv Aging 5, 45-61.
    • (2010) Clin Interv Aging , vol.5 , pp. 45-61
    • Jicha, G.A.1    Markesbery, W.R.2
  • 40
    • 76749152911 scopus 로고    scopus 로고
    • Are omega-3 fatty acids options for prevention and treatment of cognitive decline and dementia?
    • Cederholm T, Palmblad J (2010) Are omega-3 fatty acids options for prevention and treatment of cognitive decline and dementia? Curr Opin Clin Nutr Metab Care 13, 150-155.
    • (2010) Curr Opin Clin Nutr Metab Care , vol.13 , pp. 150-155
    • Cederholm, T.1    Palmblad, J.2
  • 41
    • 84855759607 scopus 로고    scopus 로고
    • The effects of long-term omega-3 fatty acid supplementation on cognition and Alzheimer's pathology in animal models of Alzheimer's disease: A systematic review and meta-analysis
    • Hooijmans CR, Pasker-de Jong PC, de Vries RB, Ritskes-Hoitinga M (2012) The effects of long-term omega-3 fatty acid supplementation on cognition and Alzheimer's pathology in animal models of Alzheimer's disease: A systematic review and meta-analysis. J Alzheimers Dis 28, 191-209.
    • (2012) J Alzheimers Dis , vol.28 , pp. 191-209
    • Hooijmans, C.R.1    Pasker-De Jong, P.C.2    De Vries, R.B.3    Ritskes-Hoitinga, M.4
  • 42
    • 40449124383 scopus 로고    scopus 로고
    • Dietary patterns in pregnant women: A comparison of foodfrequency questionnaires and 4 d prospective diaries
    • Crozier SR, Inskip HM, Godfrey KM, Robinson SM (2008) Dietary patterns in pregnant women: A comparison of foodfrequency questionnaires and 4 d prospective diaries. Br J Nutr 99, 869-875.
    • (2008) Br J Nutr , vol.99 , pp. 869-875
    • Crozier, S.R.1    Inskip, H.M.2    Godfrey, K.M.3    Robinson, S.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.