메뉴 건너뛰기




Volumn 51, Issue 9, 2014, Pages 614-622

Genetic architectures of ADME genes in five Eurasian admixed populations and implications for drug safety and efficacy

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHINA; CHINESE; COMPARATIVE STUDY; DRUG ABSORPTION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG EXCRETION; DRUG METABOLISM; DRUG RESPONSE; DRUG SAFETY; GENE FREQUENCY; GENETIC DIFFERENCE; GENETIC VARIABILITY; HAN CHINESE; HAPLOTYPE; HAPLOTYPE MAP; HETEROZYGOSITY; HUI (PEOPLE); HUMAN; KAZAKH (PEOPLE); KYRGYZ (PEOPLE); MINORITY GROUP; PHENOTYPE; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TAJIK (PEOPLE); UYGUR (PEOPLE); ASIAN CONTINENTAL ANCESTRY GROUP; CAUCASIAN; DOSE RESPONSE; ETHNIC GROUP; GENE FLOW; GENETIC VARIATION; GENETICS; PHARMACOKINETICS; POPULATION GENETICS;

EID: 84907078700     PISSN: 00222593     EISSN: 14686244     Source Type: Journal    
DOI: 10.1136/jmedgenet-2014-102530     Document Type: Article
Times cited : (22)

References (38)
  • 1
    • 31044441473 scopus 로고    scopus 로고
    • Pharmacogenetics and the concept of individualized medicine
    • Shastry BS. Pharmacogenetics and the concept of individualized medicine. Pharmacogenomics J 2006;6:16-21.
    • (2006) Pharmacogenomics J , vol.6 , pp. 16-21
    • Shastry, B.S.1
  • 2
    • 84872899545 scopus 로고    scopus 로고
    • Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects
    • Sim SC, Kacevska M, Ingelman-Sundberg M. Pharmacogenomics of drug-metabolizing enzymes: a recent update on clinical implications and endogenous effects. Pharmacogenomics J 2013;13:1-11.
    • (2013) Pharmacogenomics J , vol.13 , pp. 1-11
    • Sim, S.C.1    Kacevska, M.2    Ingelman-Sundberg, M.3
  • 4
    • 84876465406 scopus 로고    scopus 로고
    • Human loci involved in drug biotransformation: worldwide genetic variation, population structure, and pharmacogenetic implications
    • Delser PM, Fuselli S. Human loci involved in drug biotransformation: worldwide genetic variation, population structure, and pharmacogenetic implications. Hum Genet 2013;132:563-77.
    • (2013) Hum Genet , vol.132 , pp. 563-577
    • Delser, P.M.1    Fuselli, S.2
  • 5
    • 70449569063 scopus 로고    scopus 로고
    • Molecular population genetics of human CYP3A locus: signatures of positive selection and implications for evolutionary environmental medicine
    • Chen X, Wang H, Zhou G, Zhang X, Dong X, Zhi L, Jin L, He F. Molecular population genetics of human CYP3A locus: signatures of positive selection and implications for evolutionary environmental medicine. Environ Health Perspect 2009;117:1541-8.
    • (2009) Environ Health Perspect , vol.117 , pp. 1541-1548
    • Chen, X.1    Wang, H.2    Zhou, G.3    Zhang, X.4    Dong, X.5    Zhi, L.6    Jin, L.7    He, F.8
  • 6
    • 0036724899 scopus 로고    scopus 로고
    • DNA sequence variation in a 3 7-kb noncoding sequence 50 of the CYP1A2 gene: implications for human population history and natural selection
    • Wooding SP, Watkins WS, Bamshad MJ, Dunn DM, Weiss RB, Jorde LB. DNA sequence variation in a 3.7-kb noncoding sequence 50 of the CYP1A2 gene: implications for human population history and natural selection. Am J Hum Genet 2002;71:528-42.
    • (2002) Am J Hum Genet , vol.71 , pp. 528-542
    • Wooding, S.P.1    Watkins, W.S.2    Bamshad, M.J.3    Dunn, D.M.4    Weiss, R.B.5    Jorde, L.B.6
  • 7
    • 79953743009 scopus 로고    scopus 로고
    • Arylamine N-acetyltransferase 2 (NAT2) genetic diversity and traditional subsistence: a worldwide population survey
    • Sabbagh A, Darlu P, Crouau-Roy B, Poloni ES. Arylamine N-acetyltransferase 2 (NAT2) genetic diversity and traditional subsistence: a worldwide population survey. PLoS ONE 2011;6:e18507.
    • (2011) PLoS ONE , vol.6 , pp. e18507
    • Sabbagh, A.1    Darlu, P.2    Crouau-Roy, B.3    Poloni, E.S.4
  • 8
    • 78651076990 scopus 로고    scopus 로고
    • Global patterns of genetic diversity and signals of natural selection for human ADME genes
    • Li J, Zhang L, Zhou H, Stoneking M, Tang K. Global patterns of genetic diversity and signals of natural selection for human ADME genes. Hum Mol Genet 2011;20:528-40.
    • (2011) Hum Mol Genet , vol.20 , pp. 528-540
    • Li, J.1    Zhang, L.2    Zhou, H.3    Stoneking, M.4    Tang, K.5
  • 10
    • 84899937080 scopus 로고    scopus 로고
    • Applying genome-wide gene-based expression quantitative trait locus mapping to study population ancestry and pharmacogenetics
    • Yang HC, Lin CW, Chen CW, Chen JJ. Applying genome-wide gene-based expression quantitative trait locus mapping to study population ancestry and pharmacogenetics. BMC Genomics 2014;15:319.
    • (2014) BMC Genomics , vol.15 , pp. 319
    • Yang, H.C.1    Lin, C.W.2    Chen, C.W.3    Chen, J.J.4
  • 11
    • 84893138736 scopus 로고    scopus 로고
    • Pharmacogenomic implications of population admixture: Brazil as a model case
    • Suarez-Kurtz G, Paula DP, Struchiner CJ. Pharmacogenomic implications of population admixture: Brazil as a model case. Pharmacogenomics 2014;15:209-19.
    • (2014) Pharmacogenomics , vol.15 , pp. 209-219
    • Suarez-Kurtz, G.1    Paula, D.P.2    Struchiner, C.J.3
  • 12
    • 41649083148 scopus 로고    scopus 로고
    • Analysis of genomic admixture in Uyghur and its implication in mapping strategy
    • Xu S, Huang W, Qian J, Jin L. Analysis of genomic admixture in Uyghur and its implication in mapping strategy. Am J Hum Genet 2008;82:883-94.
    • (2008) Am J Hum Genet , vol.82 , pp. 883-894
    • Xu, S.1    Huang, W.2    Qian, J.3    Jin, L.4
  • 13
    • 51149090386 scopus 로고    scopus 로고
    • A genome-wide analysis of admixture in Uyghurs and a high-density admixture map for disease-gene discovery
    • Xu S, Jin L. A genome-wide analysis of admixture in Uyghurs and a high-density admixture map for disease-gene discovery. Am J Hum Genet 2008;83:322-36.
    • (2008) Am J Hum Genet , vol.83 , pp. 322-336
    • Xu, S.1    Jin, L.2
  • 16
    • 38449121822 scopus 로고    scopus 로고
    • Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia
    • Magalon H, Patin E, Austerlitz F, Hegay T, Aldashev A, Quintana-Murci L, Heyer E. Population genetic diversity of the NAT2 gene supports a role of acetylation in human adaptation to farming in Central Asia. Eur J Hum Genet 2008;16:243-51.
    • (2008) Eur J Hum Genet , vol.16 , pp. 243-251
    • Magalon, H.1    Patin, E.2    Austerlitz, F.3    Hegay, T.4    Aldashev, A.5    Quintana-Murci, L.6    Heyer, E.7
  • 20
    • 33644974019 scopus 로고    scopus 로고
    • A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase
    • Scheet P, Stephens M. A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase. Am J Hum Genet 2006;78:629-44.
    • (2006) Am J Hum Genet , vol.78 , pp. 629-644
    • Scheet, P.1    Stephens, M.2
  • 22
    • 33846057724 scopus 로고    scopus 로고
    • NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins
    • Database issue
    • Pruitt KD, Tatusova T, Maglott DR. NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res 2007;35(Database issue):D61-5.
    • (2007) Nucleic Acids Res , vol.35 , pp. D61-D65
    • Pruitt, K.D.1    Tatusova, T.2    Maglott, D.R.3
  • 23
    • 77955405475 scopus 로고    scopus 로고
    • Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor
    • McLaren W, Pritchard B, Rios D, Chen Y, Flicek P, Cunningham F. Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor. Bioinformatics 2010;26:2069-70.
    • (2010) Bioinformatics , vol.26 , pp. 2069-2070
    • McLaren, W.1    Pritchard, B.2    Rios, D.3    Chen, Y.4    Flicek, P.5    Cunningham, F.6
  • 26
    • 68949103876 scopus 로고    scopus 로고
    • Inferring weak population structure with the assistance of sample group information
    • Hubisz MJ, Falush D, Stephens M, Pritchard JK. Inferring weak population structure with the assistance of sample group information. Mol Ecol Resour 2009;9:1322-32.
    • (2009) Mol Ecol Resour , vol.9 , pp. 1322-1332
    • Hubisz, M.J.1    Falush, D.2    Stephens, M.3    Pritchard, J.K.4
  • 28
    • 33846006923 scopus 로고    scopus 로고
    • Population structure and eigenanalysis
    • Patterson N, Price AL, Reich D. Population structure and eigenanalysis. PLoS Genet 2006;2:e190.
    • (2006) PLoS Genet , vol.2 , pp. e190
    • Patterson, N.1    Price, A.L.2    Reich, D.3
  • 29
    • 77953032930 scopus 로고    scopus 로고
    • Arlequin suite ver 3 5: a new series of programs to perform population genetics analyses under Linux and Windows
    • Excoffier L, Lischer HEL. Arlequin suite ver 3.5: a new series of programs to perform population genetics analyses under Linux and Windows. Mol Ecol Resour 2010;10:564-7.
    • (2010) Mol Ecol Resour , vol.10 , pp. 564-567
    • Excoffier, L.1    Lischer, H.E.L.2
  • 30
    • 0021566877 scopus 로고
    • Estimating F-Statistics for the Analysis of Population-Structure
    • Weir BS, Cockerham CC. Estimating F-Statistics for the Analysis of Population-Structure. Evolution 1984;38:1358-70.
    • (1984) Evolution , vol.38 , pp. 1358-1370
    • Weir, B.S.1    Cockerham, C.C.2
  • 32
    • 33644981509 scopus 로고    scopus 로고
    • A map of recent positive selection in the human genome (vol 4, pg 154 2006)
    • Voight BF, Kudaravalli S, Wen XQ, Pritchard JK. A map of recent positive selection in the human genome (vol 4, pg 154, 2006). PLoS Biol 2006;4:659.
    • (2006) PLoS Biol , vol.4 , pp. 659
    • Voight, B.F.1    Kudaravalli, S.2    Wen, X.Q.3    Pritchard, J.K.4
  • 38
    • 79955422718 scopus 로고    scopus 로고
    • The fallacy of racial pharmacogenomics
    • Pena SD. The fallacy of racial pharmacogenomics. Braz J Med Biol Res 2011;44:268-75.
    • (2011) Braz J Med Biol Res , vol.44 , pp. 268-275
    • Pena, S.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.