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Volumn 155, Issue 9, 2014, Pages 3649-3660

Developmental programming: Prenatal steroid excess disrupts key members of intraovarian steroidogenic pathway in sheep

Author keywords

[No Author keywords available]

Indexed keywords

3BETA HYDROXY DELTA5 STEROID DEHYDROGENASE; ANDROSTANOLONE; AROMATASE; CYTOCHROME P450 17; ESTRADIOL; STEROID; STEROIDOGENIC ACUTE REGULATORY PROTEIN; 3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; ANDROGEN; ESTROGEN; PHOSPHOPROTEIN; STEROID 17ALPHA MONOOXYGENASE; TESTOSTERONE;

EID: 84907053794     PISSN: 00137227     EISSN: 19457170     Source Type: Journal    
DOI: 10.1210/en.2014-1266     Document Type: Article
Times cited : (32)

References (66)
  • 1
    • 0035028517 scopus 로고    scopus 로고
    • Steroid 11 β-hydroxylase deficiency and related disorders
    • vi
    • White PC. Steroid 11 β-hydroxylase deficiency and related disorders. Endocrinol Metab Clin North Am. 2001;30:61-79, vi.
    • (2001) Endocrinol Metab Clin North Am. , vol.30 , pp. 61-79
    • White, P.C.1
  • 3
    • 79959800774 scopus 로고    scopus 로고
    • Developmental origin of reproductive and metabolic dysfunctions: Androgenic versus estrogenic reprogramming
    • Padmanabhan V, Veiga-Lopez A. Developmental origin of reproductive and metabolic dysfunctions: androgenic versus estrogenic reprogramming. Semin Reprod Med. 2011;29:173-186.
    • (2011) Semin Reprod Med. , vol.29 , pp. 173-186
    • Padmanabhan, V.1    Veiga-Lopez, A.2
  • 4
    • 80053374676 scopus 로고    scopus 로고
    • Contraceptive choices, pregnancy rates, and outcomes in a microbicide trial
    • Sibeko S, Baxter C, Yende N, Karim QA, Karim SS. Contraceptive choices, pregnancy rates, and outcomes in a microbicide trial. Obstet Gynecol. 2011;118:895-904.
    • (2011) Obstet Gynecol. , vol.118 , pp. 895-904
    • Sibeko, S.1    Baxter, C.2    Yende, N.3    Karim, Q.A.4    Karim, S.S.5
  • 5
    • 45249111974 scopus 로고    scopus 로고
    • Maternal use of oral contraceptives and risk of fetal death
    • Jellesen R, Strandberg-Larsen K, et al. Maternal use of oral contraceptives and risk of fetal death. Paediatr Perinat Epidemiol. 2008; 22:334-340.
    • (2008) Paediatr Perinat Epidemiol. , vol.22 , pp. 334-340
    • Jellesen, R.1    Strandberg-Larsen, K.2
  • 6
    • 84896334017 scopus 로고    scopus 로고
    • Current exposure of 200 pregnant Danish women to phthalates, para-bens and phenols
    • Tefre de Renzy-Martin K, Frederiksen H, Christensen J, et al. Current exposure of 200 pregnant Danish women to phthalates, para-bens and phenols. Reproduction. 2014;147:443-453.
    • (2014) Reproduction. , vol.147 , pp. 443-453
    • Tefre De Renzy-Martin, K.1    Frederiksen, H.2    Christensen, J.3
  • 7
    • 84869507003 scopus 로고    scopus 로고
    • Prenatal and perinatal environmental influences on the human fetal and placental epigenome
    • Hogg K, Price EM, Hanna CW, Robinson WP. Prenatal and perinatal environmental influences on the human fetal and placental epigenome. Clin Pharmacol Ther. 2012;92:716-726.
    • (2012) Clin Pharmacol Ther. , vol.92 , pp. 716-726
    • Hogg, K.1    Price, E.M.2    Hanna, C.W.3    Robinson, W.P.4
  • 8
    • 52949101044 scopus 로고    scopus 로고
    • Environmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humans
    • Swan SH. Environmental phthalate exposure in relation to reproductive outcomes and other health endpoints in humans. Environ Res. 2008;108:177-184.
    • (2008) Environ Res. , vol.108 , pp. 177-184
    • Swan, S.H.1
  • 9
    • 76849102139 scopus 로고    scopus 로고
    • Bisphenol-A and disparities in birth outcomes: A review and directions for future research
    • Ranjit N, Siefert K, Padmanabhan V. Bisphenol-A and disparities in birth outcomes: a review and directions for future research. J Peri-natol. 2010;30:2-9.
    • (2010) J Peri-natol. , vol.30 , pp. 2-9
    • Ranjit, N.1    Siefert, K.2    Padmanabhan, V.3
  • 10
    • 0036796149 scopus 로고    scopus 로고
    • Maternal serum androgens in pregnant women with polycystic ovarian syndrome: Possible implications in prenatal an-drogenization
    • Sir-Petermann T, Maliqueo M, Angel B, Lara HE, Pérez-Bravo F, Recabarren SE. Maternal serum androgens in pregnant women with polycystic ovarian syndrome: possible implications in prenatal an-drogenization. Hum Reprod. 2002;17:2573-2579.
    • (2002) Hum Reprod. , vol.17 , pp. 2573-2579
    • Sir-Petermann, T.1    Maliqueo, M.2    Angel, B.3    Lara, H.E.4    Pérez-Bravo, F.5    Recabarren, S.E.6
  • 11
    • 28944451229 scopus 로고    scopus 로고
    • Anatomical evidence for in utero androgen exposure in women with polycystic ovary syndrome
    • Cattrall FR, Vollenhoven BJ, Weston GC. Anatomical evidence for in utero androgen exposure in women with polycystic ovary syndrome. Fertil Steril. 2005;84:1689-1692.
    • (2005) Fertil Steril. , vol.84 , pp. 1689-1692
    • Cattrall, F.R.1    Vollenhoven, B.J.2    Weston, G.C.3
  • 12
    • 0025950831 scopus 로고
    • Maturation of hypothalamic-pituitary-gonadal function in normal human fetuses: Circulating levels of gonadotropins, their common a-subunit and free testosterone, and discrepancy between immunological and biological activities of circulating follicle-stimulating hormone
    • Beck-Peccoz P, Padmanabhan V, Baggiani AM, et al. Maturation of hypothalamic-pituitary-gonadal function in normal human fetuses: circulating levels of gonadotropins, their common a-subunit and free testosterone, and discrepancy between immunological and biological activities of circulating follicle-stimulating hormone. J Clin Endocrinol Metab. 1991;73:525-532.
    • (1991) J Clin Endocrinol Metab. , vol.73 , pp. 525-532
    • Beck-Peccoz, P.1    Padmanabhan, V.2    Baggiani, A.M.3
  • 13
    • 0022501594 scopus 로고
    • Elevated concentrations of the β-subunit of human chorionic gonadotropin and testosterone in amniotic fluid of gestations of diabetic mothers
    • Barbieri RL, Saltzman DH, Torday JS, Randall RW, Frigoletto FD, Ryan KJ. Elevated concentrations of the β-subunit of human chorionic gonadotropin and testosterone in amniotic fluid of gestations of diabetic mothers. Am J Obstet Gynecol. 1986;154:1039-1043.
    • (1986) Am J Obstet Gynecol. , vol.154 , pp. 1039-1043
    • Barbieri, R.L.1    Saltzman, D.H.2    Torday, J.S.3    Randall, R.W.4    Frigoletto, F.D.5    Ryan, K.J.6
  • 14
    • 0005696315 scopus 로고
    • Neonatal deaths among infants of diabetic mothers. Postmortem findings in ninety-five infants
    • Driscoll SG, Benirschke K, Curtis GW. Neonatal deaths among infants of diabetic mothers. Postmortem findings in ninety-five infants. Am J Dis Child. 1960;100:818-835.
    • (1960) Am J Dis Child. , vol.100 , pp. 818-835
    • Driscoll, S.G.1    Benirschke, K.2    Curtis, G.W.3
  • 16
  • 17
    • 84878106884 scopus 로고    scopus 로고
    • Sheep models of polycystic ovary syndrome phenotype
    • Padmanabhan V, Veiga-Lopez A. Sheep models of polycystic ovary syndrome phenotype. Mol Cell Endocrinol. 2013;373:8-20.
    • (2013) Mol Cell Endocrinol. , vol.373 , pp. 8-20
    • Padmanabhan, V.1    Veiga-Lopez, A.2
  • 18
    • 15844418279 scopus 로고    scopus 로고
    • Definitions, prevalence and symptoms of polycystic ovaries and polycystic ovary syndrome
    • Hart R, Hickey M, Franks S. Definitions, prevalence and symptoms of polycystic ovaries and polycystic ovary syndrome. Best Pract Res Clin Obstet Gynaecol. 2004;18:671-683.
    • (2004) Best Pract Res Clin Obstet Gynaecol. , vol.18 , pp. 671-683
    • Hart, R.1    Hickey, M.2    Franks, S.3
  • 19
    • 0035127474 scopus 로고    scopus 로고
    • Current concepts in the polycystic ovary syndrome
    • Dunaif A, Thomas A. Current concepts in the polycystic ovary syndrome. Annu Rev Med. 2001;52:401-419.
    • (2001) Annu Rev Med. , vol.52 , pp. 401-419
    • Dunaif, A.1    Thomas, A.2
  • 20
    • 84874699674 scopus 로고    scopus 로고
    • NIH panel: Name change, new priorities advised for polycystic ovary syndrome
    • Hampton T. NIH panel: name change, new priorities advised for polycystic ovary syndrome. JAMA. 2013;309:386.
    • (2013) JAMA , vol.309 , pp. 386
    • Hampton, T.1
  • 21
    • 84891848498 scopus 로고    scopus 로고
    • Animal models of the polycystic ovary syndrome phenotype
    • Padmanabhan V, Veiga-Lopez A. Animal models of the polycystic ovary syndrome phenotype. Steroids. 2013;78:734-740.
    • (2013) Steroids. , vol.78 , pp. 734-740
    • Padmanabhan, V.1    Veiga-Lopez, A.2
  • 22
    • 78649864843 scopus 로고    scopus 로고
    • Developmental programming: Impact of excess prenatal testosterone on intra-uterine fetal endocrine milieu and growth in sheep
    • Veiga-Lopez A, Steckler TL, Abbott DH, et al. Developmental programming: impact of excess prenatal testosterone on intra-uterine fetal endocrine milieu and growth in sheep. Biol Reprod. 2011;84: 87-96.
    • (2011) Biol Reprod. , vol.84 , pp. 87-96
    • Veiga-Lopez, A.1    Steckler, T.L.2    Abbott, D.H.3
  • 23
    • 41549098869 scopus 로고    scopus 로고
    • Developmental programming: Deficits in reproductive hormone dynamics and ovulatory outcomes in prenatal, testosterone-treated sheep
    • Veiga-Lopez A, Ye W, Phillips DJ, Herkimer C, Knight PG, Padmanabhan V. Developmental programming: deficits in reproductive hormone dynamics and ovulatory outcomes in prenatal, testosterone-treated sheep. Biol Reprod. 2008;78:636-647.
    • (2008) Biol Reprod. , vol.78 , pp. 636-647
    • Veiga-Lopez, A.1    Ye, W.2    Phillips, D.J.3    Herkimer, C.4    Knight, P.G.5    Padmanabhan, V.6
  • 24
    • 65249103340 scopus 로고    scopus 로고
    • Developmental programming: Differential effects of prenatal testosterone and dihydrotestosterone on follicular recruitment, depletion of follicular reserve, and ovarian morphology in sheep
    • Smith P, Steckler TL, Veiga-Lopez A, Padmanabhan V. Developmental programming: differential effects of prenatal testosterone and dihydrotestosterone on follicular recruitment, depletion of follicular reserve, and ovarian morphology in sheep. Biol Reprod. 2009;80:726-736.
    • (2009) Biol Reprod. , vol.80 , pp. 726-736
    • Smith, P.1    Steckler, T.L.2    Veiga-Lopez, A.3    Padmanabhan, V.4
  • 25
    • 33645529667 scopus 로고    scopus 로고
    • Fetal programming: Prenatal testosterone treatment leads to follicular persistence/luteal defects; Partial restoration of ovarian function by cyclic progesterone treatment
    • Manikkam M, Steckler TL, Welch KB, Inskeep EK, Padmanabhan V. Fetal programming: prenatal testosterone treatment leads to follicular persistence/luteal defects; partial restoration of ovarian function by cyclic progesterone treatment. Endocrinology. 2006;147: 1997-2007.
    • (2006) Endocrinology. , vol.147 , pp. 1997-2007
    • Manikkam, M.1    Steckler, T.L.2    Welch, K.B.3    Inskeep, E.K.4    Padmanabhan, V.5
  • 26
    • 68949212460 scopus 로고    scopus 로고
    • Developmental programming: Prenatal androgen excess disrupts ovarian steroid receptor balance
    • Ortega HH, Salvetti NR, Padmanabhan V. Developmental programming: prenatal androgen excess disrupts ovarian steroid receptor balance. Reproduction. 2009;137:865-877.
    • (2009) Reproduction. , vol.137 , pp. 865-877
    • Ortega, H.H.1    Salvetti, N.R.2    Padmanabhan, V.3
  • 27
    • 0025316615 scopus 로고
    • Steroidogenic cytochrome P450 enzymes and ovarian steroidogenesis
    • Rodgers RJ. Steroidogenic cytochrome P450 enzymes and ovarian steroidogenesis. Reprod Fertil Dev. 1990;2:153-163.
    • (1990) Reprod Fertil Dev. , vol.2 , pp. 153-163
    • Rodgers, R.J.1
  • 28
    • 33744933179 scopus 로고    scopus 로고
    • Ovarian steroids: The good, the bad, and the signals that raise them
    • Jamnongjit M, Hammes SR. Ovarian steroids: the good, the bad, and the signals that raise them. Cell Cycle. 2006;5:1178-1183.
    • (2006) Cell Cycle. , vol.5 , pp. 1178-1183
    • Jamnongjit, M.1    Hammes, S.R.2
  • 29
    • 0842334585 scopus 로고    scopus 로고
    • Fetal programming: Prenatal testosterone excess leads to fetal growth retardation and postnatal catch-up growth in sheep
    • Manikkam M, Crespi EJ, Doop DD, et al. Fetal programming: prenatal testosterone excess leads to fetal growth retardation and postnatal catch-up growth in sheep. Endocrinology. 2004;145:790-798.
    • (2004) Endocrinology. , vol.145 , pp. 790-798
    • Manikkam, M.1    Crespi, E.J.2    Doop, D.D.3
  • 30
    • 77953857781 scopus 로고    scopus 로고
    • Developmental programming: Effect of prenatal steroid excess on intraovarian components of insulin signaling pathway and related proteins in sheep
    • Ortega HH, Rey F, Velazquez MM, Padmanabhan V. Developmental programming: effect of prenatal steroid excess on intraovarian components of insulin signaling pathway and related proteins in sheep. Biol Reprod. 2010;82:1065-1075.
    • (2010) Biol Reprod. , vol.82 , pp. 1065-1075
    • Ortega, H.H.1    Rey, F.2    Velazquez, M.M.3    Padmanabhan, V.4
  • 31
    • 84869206639 scopus 로고    scopus 로고
    • Developmental programming: Impact of prenatal testosterone excess on ovarian cell proliferation and apoptotic factors in sheep
    • Salvetti NR, Ortega HH, Veiga-Lopez A, Padmanabhan V. Developmental programming: impact of prenatal testosterone excess on ovarian cell proliferation and apoptotic factors in sheep. Biol Reprod. 2012;87:221-210.
    • (2012) Biol Reprod. , vol.87 , pp. 221-210
    • Salvetti, N.R.1    Ortega, H.H.2    Veiga-Lopez, A.3    Padmanabhan, V.4
  • 34
    • 0023037552 scopus 로고
    • Cell-specific expression of immuno-reactive cholesterol side-chain cleavage cytochrome P-450 during follicular development in the rat ovary
    • Zlotkin T, Farkash Y, Orly J. Cell-specific expression of immuno-reactive cholesterol side-chain cleavage cytochrome P-450 during follicular development in the rat ovary. Endocrinology. 1986;119: 2809-2820.
    • (1986) Endocrinology. , vol.119 , pp. 2809-2820
    • Zlotkin, T.1    Farkash, Y.2    Orly, J.3
  • 35
    • 0024530892 scopus 로고
    • Further immunocytochemical study on the localization of aroma-tase in the ovary of rats and mice
    • Ishimura K, Yoshinaga-Hirabayashi T, Tsuri H, Fujita H, Osawa Y. Further immunocytochemical study on the localization of aroma-tase in the ovary of rats and mice. Histochemistry. 1989;90:413-416.
    • (1989) Histochemistry. , vol.90 , pp. 413-416
    • Ishimura, K.1    Yoshinaga-Hirabayashi, T.2    Tsuri, H.3    Fujita, H.4    Osawa, Y.5
  • 36
    • 0023023046 scopus 로고
    • Immunolocalization of cholesterol side-chain cleavage cytochrome P-450 an 17 a-hydroxylase cytochrome P-450 in bovine ovarian follicles
    • Rodgers RJ, Rodgers HF, Hall PF, Waterman MR, Simpson ER. Immunolocalization of cholesterol side-chain cleavage cytochrome P-450 an 17 a-hydroxylase cytochrome P-450 in bovine ovarian follicles. J Reprod Fertil. 1986;78:627-638.
    • (1986) J Reprod Fertil. , vol.78 , pp. 627-638
    • Rodgers, R.J.1    Rodgers, H.F.2    Hall, P.F.3    Waterman, M.R.4    Simpson, E.R.5
  • 38
    • 0028839014 scopus 로고
    • Expression of messenger ribonucleic acid encoding cytochrome P450 side-chain cleavage, cytochrome p450 17 a-hy-droxylase, and cytochrome P450 aromatase in bovine follicles during the first follicular wave
    • Xu Z, Garverick HA, Smith GW, Smith MF, Hamilton SA, Youngquist RS. Expression of messenger ribonucleic acid encoding cytochrome P450 side-chain cleavage, cytochrome p450 17 a-hy-droxylase, and cytochrome P450 aromatase in bovine follicles during the first follicular wave. Endocrinology. 1995;136:981-989.
    • (1995) Endocrinology. , vol.136 , pp. 981-989
    • Xu, Z.1    Garverick, H.A.2    Smith, G.W.3    Smith, M.F.4    Hamilton, S.A.5    Youngquist, R.S.6
  • 39
    • 0029998837 scopus 로고    scopus 로고
    • Comparison of cellular distribution of LH receptors and steroidogenic enzymes in the porcine ovary
    • Meduri G, Vu Hai MT, Jolivet A, et al. Comparison of cellular distribution of LH receptors and steroidogenic enzymes in the porcine ovary. J Endocrinol. 1996;148:435-446.
    • (1996) J Endocrinol. , vol.148 , pp. 435-446
    • Meduri, G.1    Vu Hai, M.T.2    Jolivet, A.3
  • 40
    • 0024599859 scopus 로고
    • Immunolocalization of aromatase, 17 a-hydroxylase and side-chain-cleavage cytochromes P-450 in the human ovary
    • Sasano H, Okamoto M, Mason JI, et al. Immunolocalization of aromatase, 17 a-hydroxylase and side-chain-cleavage cytochromes P-450 in the human ovary. J Reprod Fertil. 1989;85:163-169.
    • (1989) J Reprod Fertil. , vol.85 , pp. 163-169
    • Sasano, H.1    Okamoto, M.2    Mason, J.I.3
  • 41
    • 0026476605 scopus 로고
    • Immunohistochemical localization of 17 a-hydroxylase/C17-20 lyase and aromatase cytochrome P-450 in the human ovary during the menstrual cycle
    • Tamura T, Kitawaki J, Yamamoto T, et al. Immunohistochemical localization of 17 a-hydroxylase/C17-20 lyase and aromatase cytochrome P-450 in the human ovary during the menstrual cycle. J Endocrinol. 1992;135:589-595.
    • (1992) J Endocrinol. , vol.135 , pp. 589-595
    • Tamura, T.1    Kitawaki, J.2    Yamamoto, T.3
  • 42
    • 0036195671 scopus 로고    scopus 로고
    • Onset of steroidogenic enzyme gene expression during ovarian follicular development in sheep
    • Logan KA, Juengel JL, McNatty KP. Onset of steroidogenic enzyme gene expression during ovarian follicular development in sheep. Biol Reprod. 2002;66:906-916.
    • (2002) Biol Reprod. , vol.66 , pp. 906-916
    • Logan, K.A.1    Juengel, J.L.2    McNatty, K.P.3
  • 43
    • 34547092604 scopus 로고    scopus 로고
    • Control of ovarian follicular development to the gonadotrophin-dependent phase: A 2006 perspective
    • McNatty KP, Reader K, Smith P, Heath DA, Juengel JL. Control of ovarian follicular development to the gonadotrophin-dependent phase: a 2006 perspective. Soc Reprod Fertil Suppl. 2007;64:55-68.
    • (2007) Soc Reprod Fertil Suppl. , vol.64 , pp. 55-68
    • McNatty, K.P.1    Reader, K.2    Smith, P.3    Heath, D.A.4    Juengel, J.L.5
  • 44
    • 0022560082 scopus 로고
    • Adenosine cyclic 3', 5'-monophosphate and steroid production by small ovarian follicles from Booroola ewes with and without a fecundity gene
    • McNatty KP, Kieboom LE, McDiarmid J, Heath DA, Lun S. Adenosine cyclic 3', 5'-monophosphate and steroid production by small ovarian follicles from Booroola ewes with and without a fecundity gene. J Reprod Fertil. 1986;76:471-480.
    • (1986) J Reprod Fertil. , vol.76 , pp. 471-480
    • McNatty, K.P.1    Kieboom, L.E.2    McDiarmid, J.3    Heath, D.A.4    Lun, S.5
  • 45
    • 84861369568 scopus 로고    scopus 로고
    • Prenatal hyperandrogeniza-tion induces metabolic and endocrine alterations which depend on the levels of testosterone exposure
    • Amalfi S, Velez LM, Heber MF, et al. Prenatal hyperandrogeniza-tion induces metabolic and endocrine alterations which depend on the levels of testosterone exposure. PloS ONE. 2012;7:e37658.
    • (2012) PloS ONE. , vol.7 , pp. e37658
    • Amalfi, S.1    Velez, L.M.2    Heber, M.F.3
  • 46
    • 69249116992 scopus 로고    scopus 로고
    • Disruption in the expression and immunolocalisation of steroid receptors and steroidogenic enzymes in letrozole-induced polycystic ovaries in rat
    • Zurvarra FM, Salvetti NR, Mason JI, Velazquez MM, Alfaro NS, Ortega HH. Disruption in the expression and immunolocalisation of steroid receptors and steroidogenic enzymes in letrozole-induced polycystic ovaries in rat. Reprod Fertil Dev. 2009;21:827-839.
    • (2009) Reprod Fertil Dev. , vol.21 , pp. 827-839
    • Zurvarra, F.M.1    Salvetti, N.R.2    Mason, J.I.3    Velazquez, M.M.4    Alfaro, N.S.5    Ortega, H.H.6
  • 47
    • 84875213278 scopus 로고    scopus 로고
    • Letrozole increases ovarian growth and Cyp17a1 gene expression in the rat ovary
    • Ortega I, Sokalska A, Villanueva JA, et al. Letrozole increases ovarian growth and Cyp17a1 gene expression in the rat ovary. Fertil Steril. 2013;99:889-896.
    • (2013) Fertil Steril. , vol.99 , pp. 889-896
    • Ortega, I.1    Sokalska, A.2    Villanueva, J.A.3
  • 48
    • 84455188274 scopus 로고    scopus 로고
    • Enhanced thecal androgen production is prenatally programmed in an ovine model of polycystic ovary syndrome
    • Hogg K, Young JM, Oliver EM, Souza CJ, McNeilly AS, Duncan WC. Enhanced thecal androgen production is prenatally programmed in an ovine model of polycystic ovary syndrome. Endocrinology. 2012;153:450-461.
    • (2012) Endocrinology. , vol.153 , pp. 450-461
    • Hogg, K.1    Young, J.M.2    Oliver, E.M.3    Souza, C.J.4    McNeilly, A.S.5    Duncan, W.C.6
  • 49
    • 79955376303 scopus 로고    scopus 로고
    • Prenatal androgen exposure leads to alterations in gene and protein expression in the ovine fetal ovary
    • Hogg K, McNeilly AS, Duncan WC. Prenatal androgen exposure leads to alterations in gene and protein expression in the ovine fetal ovary. Endocrinology. 2011;152:2048-2059.
    • (2011) Endocrinology. , vol.152 , pp. 2048-2059
    • Hogg, K.1    McNeilly, A.S.2    Duncan, W.C.3
  • 52
    • 34347223688 scopus 로고    scopus 로고
    • Developmental programming: Follicular persistence in prenatal testosterone-treated sheep is not programmed by androgenic actions of testosterone
    • Steckler T, Manikkam M, Inskeep EK, Padmanabhan V. Developmental programming: follicular persistence in prenatal testosterone-treated sheep is not programmed by androgenic actions of testosterone. Endocrinology. 2007;148:3532-3540.
    • (2007) Endocrinology. , vol.148 , pp. 3532-3540
    • Steckler, T.1    Manikkam, M.2    Inskeep, E.K.3    Padmanabhan, V.4
  • 53
    • 84882580045 scopus 로고    scopus 로고
    • Cortisol production in sheep is influenced by the functional expression of two cytochrome P450 17a-hydroxylase/17, 20-lyase (CYP17) isoforms
    • Hough D, Cloete SW, Storbeck K, Swart AC, Swart P. Cortisol production in sheep is influenced by the functional expression of two cytochrome P450 17a-hydroxylase/17, 20-lyase (CYP17) isoforms. J Anim Sci. 2013;91:1193-1206.
    • (2013) J Anim Sci. , vol.91 , pp. 1193-1206
    • Hough, D.1    Cloete, S.W.2    Storbeck, K.3    Swart, A.C.4    Swart, P.5
  • 54
    • 28044470748 scopus 로고    scopus 로고
    • Cytochrome b(5) modulation of 17a hydroxylase and 17-20 lyase (CYP17) activities in steroidogenesis
    • Akhtar MK, Kelly SL, Kaderbhai MA. Cytochrome b(5) modulation of 17a hydroxylase and 17-20 lyase (CYP17) activities in steroidogenesis. J Endocrinol. 2005;187:267-274.
    • (2005) J Endocrinol. , vol.187 , pp. 267-274
    • Akhtar, M.K.1    Kelly, S.L.2    Kaderbhai, M.A.3
  • 55
    • 82355165023 scopus 로고    scopus 로고
    • Developmental programming: Gestational testosterone treatment alters fetal ovarian gene expression
    • Luense LJ, Veiga-Lopez A, Padmanabhan V, Christenson LK. Developmental programming: gestational testosterone treatment alters fetal ovarian gene expression. Endocrinology. 2011;152:4974-4983.
    • (2011) Endocrinology. , vol.152 , pp. 4974-4983
    • Luense, L.J.1    Veiga-Lopez, A.2    Padmanabhan, V.3    Christenson, L.K.4
  • 56
    • 84907053743 scopus 로고    scopus 로고
    • Expression of steroidogenic enzymes in the rat model of polycystic ovary syndrome
    • Lin W, Song ZJ, Sun WM, et al. [Expression of steroidogenic enzymes in the rat model of polycystic ovary syndrome]. Sheng Li Xue Bao. 2013;65:171-177.
    • (2013) Sheng Li Xue Bao. , vol.65 , pp. 171-177
    • Lin, W.1    Song, Z.J.2    Sun, W.M.3
  • 57
    • 84857782237 scopus 로고    scopus 로고
    • Developmental programming: Prenatal testosterone excess disrupts anti-Müllerian hormone expression in preantral and antral follicles
    • Veiga-Lopez A, Ye W, Padmanabhan V. Developmental programming: prenatal testosterone excess disrupts anti-Müllerian hormone expression in preantral and antral follicles. Fertil Steril. 2012;97: 748-756.
    • (2012) Fertil Steril. , vol.97 , pp. 748-756
    • Veiga-Lopez, A.1    Ye, W.2    Padmanabhan, V.3
  • 58
    • 0035051203 scopus 로고    scopus 로고
    • Luteinizing hormone receptor, steroidogenesis acute regulatory protein, and steroidogenic enzyme messenger ribonucleic acids are overexpressed in thecal and granulosa cells from polycystic ovaries
    • Jakimiuk AJ, Weitsman SR, Navab A, Magoffin DA. Luteinizing hormone receptor, steroidogenesis acute regulatory protein, and steroidogenic enzyme messenger ribonucleic acids are overexpressed in thecal and granulosa cells from polycystic ovaries. J Clin Endocrinol Metab. 2001;86:1318-1323.
    • (2001) J Clin Endocrinol Metab. , vol.86 , pp. 1318-1323
    • Jakimiuk, A.J.1    Weitsman, S.R.2    Navab, A.3    Magoffin, D.A.4
  • 59
    • 15944407338 scopus 로고    scopus 로고
    • Dysregulation of cytochrome P450 17a-hydroxylase messenger ribonucleic acid stability in theca cells isolated from women with polycystic ovary syndrome
    • Wickenheisser JK, Velen L, Nelson-Degrave VL, McAllister JM. Dysregulation of cytochrome P450 17a-hydroxylase messenger ribonucleic acid stability in theca cells isolated from women with polycystic ovary syndrome. J Clin Endocrinol Metab. 2005;90: 1720-1727.
    • (2005) J Clin Endocrinol Metab. , vol.90 , pp. 1720-1727
    • Wickenheisser, J.K.1    Velen, L.2    Nelson-Degrave, V.L.3    McAllister, J.M.4
  • 60
    • 0035217099 scopus 로고    scopus 로고
    • The biochemical basis for increased testosterone production in theca cells propagated from patients with polycystic ovary syndrome
    • Nelson VL, Qin KN, Rosenfield RL, et al. The biochemical basis for increased testosterone production in theca cells propagated from patients with polycystic ovary syndrome. J Clin Endocrinol Metab. 2001;86:5925-5933.
    • (2001) J Clin Endocrinol Metab. , vol.86 , pp. 5925-5933
    • Nelson, V.L.1    Qin, K.N.2    Rosenfield, R.L.3
  • 61
    • 0036147995 scopus 로고    scopus 로고
    • Overexpression of theca-cell messenger RNA in polycystic ovary syndrome does not correlate with polymorphisms in the cholesterol side-chain cleavage and 17a-hydroxylase/C(17-20) lyase promoters
    • Daneshmand S, Weitsman SR, Navab A, Jakimiuk AJ, Magoffin DA. Overexpression of theca-cell messenger RNA in polycystic ovary syndrome does not correlate with polymorphisms in the cholesterol side-chain cleavage and 17a-hydroxylase/C(17-20) lyase promoters. Fertil Steril. 2002;77:274-280.
    • (2002) Fertil Steril. , vol.77 , pp. 274-280
    • Daneshmand, S.1    Weitsman, S.R.2    Navab, A.3    Jakimiuk, A.J.4    Magoffin, D.A.5
  • 64
    • 84885914992 scopus 로고    scopus 로고
    • Increased protein expression of LHCG receptor and 17a-hydroxylase/17-20-lyase in human polycystic ovaries
    • Comim FV, Teerds K, Hardy K, Franks S. Increased protein expression of LHCG receptor and 17a-hydroxylase/17-20-lyase in human polycystic ovaries. Human Reproduction. 2013;28:3086-3092.
    • (2013) Human Reproduction. , vol.28 , pp. 3086-3092
    • Comim, F.V.1    Teerds, K.2    Hardy, K.3    Franks, S.4
  • 65
    • 84861737570 scopus 로고    scopus 로고
    • Association study of CYP17 and HSD11B1 in polycystic ovary syndrome utilizing comprehensive gene coverage
    • Chua AK, Azziz R, Goodarzi MO. Association study of CYP17 and HSD11B1 in polycystic ovary syndrome utilizing comprehensive gene coverage. Mol Hum Reprod. 2012;18:320-324.
    • (2012) Mol Hum Reprod. , vol.18 , pp. 320-324
    • Chua, A.K.1    Azziz, R.2    Goodarzi, M.O.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.