Paradigm shifts in heart-failure therapy - A timeline

New England Journal of Medicine

Volumn 371, Issue 11, 2014, Pages 989-991

  Sacks, Chana A ^a   Jarcho, John A ^a   Curfman, Gregory D ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

3 (1 BIPHENYL 4 YLMETHYL 3 ETHOXYCARBONYL 1 BUTYLCARBAMOYL)PROPIONIC ACID PLUS VALSARTAN; ANGIOTENSIN RECEPTOR ANTAGONIST; BISOPROLOL; CARVEDILOL; DIGOXIN; ENALAPRIL; EPLERENONE; HYDRALAZINE PLUS ISOSORBIDE DINITRATE; METOPROLOL; MILRINONE; NESIRITIDE; PLACEBO; PRAZOSIN; SPIRONOLACTONE;

CARDIAC RESYNCHRONIZATION THERAPY; CARDIAC RESYNCHRONIZATION THERAPY DEVICE; CARDIOVASCULAR MORTALITY; DRUG EFFICACY; DYSPNEA; HEART EJECTION FRACTION; HEART FAILURE; HOSPITALIZATION; HUMAN; IMPLANTABLE CARDIOVERTER DEFIBRILLATOR; LEFT VENTRICULAR ASSIST DEVICE; QRS COMPLEX; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SYSTOLIC HEART FAILURE; VASODILATATION; VENTRICULAR PACEMAKER; ARTICLE; HISTORY; THERAPY;

HEART FAILURE; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; THERAPEUTICS;

EID: 84907053688     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMp1410241     Document Type: Article

References (21)

1. 1986. V-HeFT I. Cohn JN, Archibald DG, Ziesche S, et al. Effect of vasodilator therapy on mortality in chronic congestive heart failure. 314: 1547-52.
2. 1987. CONSENSUS. The Consensus Trial Study Group. Effects of enalapril on mortality in severe congestive heart failure. 316: 1429-35.
3. 1991a. SOLVD-Treatment. The SOLVD Investigators. Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. 325: 293-302.
4. 1991b. V-HeFT II. Cohn JN, Johnson G, Ziesche S, et al. A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. 325: 303-10.
5. 1991c. PROMISE. Packer M, Carver JR, Rodeheffer RJ, et al. Effect of oral milrinone on mortality in severe chronic heart failure. 325: 1468-75.
6. 1992. SOLVD-Prevention. The SOLVD Investigators. Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. 327: 685-91.
7. 1996. U.S. Carvedilol Heart Failure Study Group. Packer M, Bristow MR, Cohn JN, et al. The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. 334: 1349-55.
8. 1997. DIG. The Digitalis Investigation Group. The effect of digoxin on mortality and morbidity in patients with heart failure. 336: 525-33.
9. 1999. RALES. Pitt B, Zannad F, Remme WJ, et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. 341: 709-17.
10. 2001a. COPERNICUS. Packer M, Coats AJS, Fowler MB, et al. Effect of carvedilol on survival in severe chronic heart failure. 344: 1651-8.
11. 2001b. REMATCH. Rose EA, Gelijns AC, Moskowitz AJ, et al. Long-term use of a left ventricular assist device for end-stage heart failure. 345: 1435-43.
12. 2001c. Val-HeFT. Cohn JN, Tognoni G. A randomized trial of the angiotensinreceptor blocker valsartan in chronic heart failure. 345: 1667-75.
13. 2004. COMPANION. Bristow MR, Saxon LA, Boehmer J, et al. Cardiacresynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. 350: 2140-50.
14. 2005a. SCD-HeFT. Bardy GH, Lee KL, Mark DB, et al. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. 352: 225-37.
15. 2005b. CARE-HF. Cleland JGF, Daubert J-C, Erdmann E, et al. The effect of cardiac resynchronization on morbidity and mortality in heart failure. 352: 1539-49.
16. 2009. MADIT-CRT. Moss AJ, Hall WJ, Cannom DS, et al. Cardiac-resynchronization therapy for the prevention of heart-failure events. 361: 1329-38.
17. 2010. RAFT. Tang ASL, Wells GA, Talajic M, et al. Cardiac-resynchronization therapy for mild-to-moderate heart failure. 363: 2385-95.
18. 2011a. EMPHASIS-HF. Zannad F, McMurray JJV, Krum H, et al. Eplerenone in patients with systolic heart failure and mild symptoms. 364: 11-21.
19. 2011b. ASCEND-HF. O'Connor CM, Starling RC, Hernandez AF, et al. Effect of nesiritide in patients with acute decompensated heart failure. 365: 32-43.
20. 2014a. MADIT-CRT follow-up. Goldenberg I, Kutyifa V, Klein HU, et al. Survival with cardiac-resynchronization therapy in mild heart failure. 370: 1694-701.
21. 2014b. PARADIGM-HF. McMurray JJV, Packer M, Desai AS, et al. Angiotensin-neprilysin inhibition versus enalapril in heart failure. DOI: 10.1056/NEJMoa1409077.