The epidemiology and distribution of pathogens and risk factors for mortality in liver transplant recipients with gram negative bacteremia

Hepato-Gastroenterology

Volumn 61, Issue 134, 2014, Pages 1730-1733

  Wan, Qiquan ^a   Ye, Qifa ^a   Su, Tao ^b   Zhou, Jiandang ^a  

^a THE THIRD XIANGYA HOSPITAL OF CENTRAL SOUTH UNIVERSITY   (China)

^b CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Bacteremia; Gram negative bacteria; Liver transplantation; Mortality; Risk factors

Indexed keywords

CORTICOSTEROID; CYCLOSPORIN A; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; SERUM ALBUMIN; TACROLIMUS; ALB PROTEIN, HUMAN; BIOLOGICAL MARKER;

ADOLESCENT; ADULT; AGED; ARTICLE; COHORT ANALYSIS; DISEASE ASSOCIATION; ESCHERICHIA COLI; FEMALE; GRAFT RECIPIENT; GRAM NEGATIVE SEPSIS; HUMAN; LIVER DYSFUNCTION; LIVER GRAFT; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RISK FACTOR; SEPTIC SHOCK; YOUNG ADULT; BACTEREMIA; BLOOD; CHI SQUARE DISTRIBUTION; CHINA; CLINICAL TRIAL; EPIDEMIOLOGY; GRAM NEGATIVE BACTERIUM; GRAM-NEGATIVE BACTERIAL INFECTIONS; HYPOALBUMINEMIA; ISOLATION AND PURIFICATION; LIVER TRANSPLANTATION; MICROBIOLOGY; MULTICENTER STUDY; MULTIVARIATE ANALYSIS; RETROSPECTIVE STUDY; RISK; STATISTICAL MODEL; TREATMENT OUTCOME;

ADULT; BACTEREMIA; BIOLOGICAL MARKERS; CHI-SQUARE DISTRIBUTION; CHINA; FEMALE; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; HYPOALBUMINEMIA; LIVER TRANSPLANTATION; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; RETROSPECTIVE STUDIES; RISK FACTORS; SERUM ALBUMIN; SHOCK, SEPTIC; TREATMENT OUTCOME;

EID: 84906958214     PISSN: 01726390     EISSN: None     Source Type: Journal    
DOI: 10.5754/hge14504     Document Type: Article

References (30)

1. Kim S, Kim Y, Jun Y, et al. Epidemiology and risk factors for bacteremia in 144 consecutive living-donor liver transplant recipients. Yonsei Med J 2009; 50: 112-121.
2. Wagener MM, Yu VL: Bacteremia in transplant recipients: a prospective study of demographics, etiologic agents, risk factors and outcomes. Am J Infect Control 1992; 20: 239-247.
3. Bert F, Larroque B, Paugam-Burtz C, et al. Microbial epidemiology and outcome of bloodstream infections in liver transplant recipients: An analysis of 259 episodes. Liver Transpl 2010; 16: 393-401.
4. Moreno A, Cervera C, Gavalda J, et al. Bloodstream infections among transplant recipients: results of a nationwide surveillance in Spain. Am J Transplant 2007; 7: 2579-2586. (Pubitemid 47561608)
5. Singh N, Gayowski T, Wagener MM, Marino IR. Bloodstream infections in liver transplant recipients receiving tacrolimus. Clin Transplant 1997; 11: 275-281. (Pubitemid 27331157)
6. Wade JJ, Rolando N, Hayllar K, Philpott-Howard J, Casewell MW, Williams R. Bacterial and fungal infections after liver transplantation: an analysis of 284 patients. Hepatology 1995; 21: 1328-1336.
7. Singh N, Paterson DL, Gayowski T, et al: Predicting bacteremia and bacteremic mortality in liver transplant recipients. Liver Transpl 2000; 6: 54-61. (Pubitemid 30123368)
8. J. Hsu, D. R. Andes, V. Knasinski, et al: Statins are associated with improved outcomes of bloodstream infection in solid-organ transplant recipients. Eur J Clin Microbiol Infect Dis 2009; 28: 1343-1351.
9. Iida T, Kaido T, Yagi S, et al. Posttransplant bacteremia in adult living donor liver transplant recipients. Liver Transpl 2010; 16: 1379-1385.
10. Kim HK, Park YK, Wang HJ, et al. Epidemiology and Clinical Features of Post-Transplant Bloodstream Infection: An Analysis of 222 Consecutive Liver Transplant Recipients. Infect Chemother 2013; 45: 315-324.
11. Al-Hasan MN, Razonable RR, Eckel-Passow JE, et al. Incidence rate and outcome of Gram-negative bloodstream infection in solid organ transplant recipients. Am J Transplant 2009; 9: 835-843.
12. Levry MM, Fink MP, Marshall JC, et al, for the international sepsis definitions conference. 2001 SCCM/ESICM/ACCP/ATS/SIS International sepsis definition conference. Intensive Care Med 2003; 29: 530-538. (Pubitemid 36523666)
13. Kusne S, Dummer JS, Singh N, et al. Infections after liver transplantation: an analysis of 101 consecutive cases. Medicine 1988; 67: 132-143.
14. George DL, Arnow PM, Fox AS, et al. Bacterial infection as a complication of liver transplantation: epidemiology and risk factors. Rev Infect Dis 1991; 13: 387-396.
15. Singh N, Wagener MM, Obman A, et al. Bacteremias in liver transplant recipients: shift toward gram-negative bacteria as predominant pathogens. Liver Transpl 2004; 10: 844-849. (Pubitemid 38979253)
16. Hashimoto M, Sugawara Y, Tamura S, et al. Bloodstream infection after living donor liver transplantation. Scand J Infect Dis 2008; 40: 509-516. (Pubitemid 351997669)
17. Shi SH, Kong HS, Xu J, et al. Multidrug resistant gram-negative bacilli as predominant bacteremic pathogens in liver transplant recipients. Transplant Infect Dis 2009; 11: 405-412.
18. Sganga G, Spanu T, Bianco G, et al. Bacterial bloodstream infections in liver transplantation: Etiologic agents and antimicrobial susceptibility profiles. Transplant Proc 2012; 44: 1973-1976.
19. Perić Z, Tambić-Andrasević A, Mrzljak A, et al. Bloodstream infections after liver and hematopoietic stem cell transplantation. Acta Med Croatica 2012; 66: 365-373.
20. Fulginiti VA, Scribner R, Groth CG, et al. Infections in recipients of liver homografts. N Engl J Med 1968; 279: 619-626.
21. Colonna JO 2nd, Winston DJ, Brill JE, et al. Infectious Complications in Liver Transplantation. Arch Surg 1988; 123: 360-364. (Pubitemid 18093308)
22. Korvick JA, Marsh JW, Starzl TE, et al. Pseudomonas aeruginosa bacteremia in patients undergoing liver transplantation: an emerging problem. Surgery 1991; 109: 62-68.
23. Wan QQ, Ye QF, Ming YZ, et al. The risk factors for mortality in deceased donor liver transplant recipients with bloodstream infections. Transplant Proc 2013; 45: 305-307.
24. Plevak DJ, Southorn PA, Narr BJ. Intensive care unit experience in the Mayo liver transplant program: The first 100 cases. Mayo Clin Proc 1989; 64: 433-445. (Pubitemid 19130653)
25. Shieh RM, Chen CL, Wang KL. Respiratory changes and pulmonary complications following orthotopic liver transplantation. Transplant Proc 1992; 24: 1486-1488.
26. Torre-Cisneros J, Herrero C, Canas E, et al. High mortality related with Staphylococcus aureus. Eur J Clin Microbiol Infect Dis 2002; 21: 385-388.
27. Nieto-Rodriguez JA, Kusne S, Mañez R, et al. Factors associated with the development of candidemia and candidemia-related death among liver transplant recipients. Ann Surg 1996; 223: 70-76.
28. Candel FJ, Grima E, Matesanz M, et al. Bacteremia and septic shock after solid-organ transplantation. Transplant Proc 2005; 37: 4097-4099. (Pubitemid 43015263)
29. Rothschild MA, Oratz M, Schreiber SS. Serum albumin. Hepatology 1988; 8: 385-401.
30. ASPEN Board of Directors and the Clinical Guidelines Task Force. Guidelines for the use of parenteral and enteral nutrition in adult and paediatric patients. JPEN J Parenter Enteral Nutr 2002; 26(Suppl 1): SA1-138.