Hypothalamic-pituitary-adrenal axis activity, personality traits, and BCL1 and N363S polymorphisms of the glucocorticoid receptor gene in metabolically obese normal-weight women

Endocrine

Volumn 47, Issue 1, 2014, Pages 315-321

  Porzezińska Furtak, Joanna ^a   Krzyżanowska Świniarska, Barbara ^a   Miazgowski, Tomasz ^a   Safranow, Krzysztof ^a   Kamiński, Ryszard ^b  

^a POMERANIAN MEDICAL UNIVERSITY   (Poland)

^b Department of Oncology   (Poland)

Author keywords

Copeptin; Cortisol; Glucocorticoid receptor gene; Metabolically obese normal weight; Personality traits

Indexed keywords

CHOLESTEROL; COPEPTIN; CORTICOTROPIN; DEXAMETHASONE; GLUCOCORTICOID RECEPTOR; GLUCOSE; HIGH DENSITY LIPOPROTEIN; HYDROCORTISONE; INSULIN; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL; ENDODEOXYRIBONUCLEASE BCLI; TYPE II SITE SPECIFIC DEOXYRIBONUCLEASE;

ADULT; ARTICLE; BODY COMPOSITION; BODY FAT DISTRIBUTION; CHOLESTEROL BLOOD LEVEL; CLINICAL FEATURE; CONTROLLED STUDY; CORTICOTROPIN BLOOD LEVEL; COURTAULD EMOTIONAL CONTROL SCALE; DEXAMETHASONE SUPPRESSION TEST; DISEASE ASSOCIATION; EMOTIONALITY; EXTRAVERSION; FAT FREE MASS; FEMALE; GENETIC POLYMORPHISM; GLUCOCORTICOID RECEPTOR GENE; GLUCOSE BLOOD LEVEL; HUMAN; HYDROCORTISONE BLOOD LEVEL; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INSULIN BLOOD LEVEL; LIPID STORAGE; LIPOPROTEIN BLOOD LEVEL; MAJOR CLINICAL STUDY; METABOLICALLY OBESE NORMAL WEIGHT INDIVIDUAL; NEO FIVE FACTOR INVENTORY; NEUROSIS; OBESITY; PERSONALITY; PHENOTYPE; PRIORITY JOURNAL; PSYCHOLOGICAL RATING SCALE; TRIACYLGLYCEROL BLOOD LEVEL; WAIST CIRCUMFERENCE; BODY WEIGHT; CASE CONTROL STUDY; GENETICS; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; METABOLISM; QUESTIONNAIRE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; YOUNG ADULT;

ADULT; CASE-CONTROL STUDIES; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; FEMALE; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; IDEAL BODY WEIGHT; OBESITY; PERSONALITY; PITUITARY-ADRENAL SYSTEM; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; QUESTIONNAIRES; RECEPTORS, GLUCOCORTICOID; YOUNG ADULT;

EID: 84906937426     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-014-0187-0     Document Type: Article

References (35)

1. N.B. Ruderman, P. Brechtold, S.H. Schneider, Obesity associated disorders in normal weight individuals: some speculations. Int. J. Obes. 6, 151-157 (1982)
2. A. Katsuki, Y. Sumida, H. Urakawa, Increased visceral fat and serum levels of triglyceride are associated with insulin resistance in Japanese metabolically obese, normal weight subjects with normal glucose tolerance. Diabetes Care 26, 2341-2344 (2003)
3. F. Conus, D.B. Allison, R. Rabasa-Lhoret, M. St-Onge, D.H. St-Pierre, A. Tremblay-Lebeau, E.T. Poehlman, Metabolic and behavioral characteristic of metabolically obese but normal-weight women. J. Clin. Endocrinol. Metab. 89, 5013-5020 (2004)
4. R.V. Dvorak, W.F. DeNino, P.A. Ades, Phenotypic characteristics associated with insulin resistance in metabolically obese but normal weight young women. Diabetes 48, 2210-2214 (1998)
5. J.B. Meigs, P.W. Wilson, C.S. Fox, R.S. Vasan, D.M. Nathan, L.M. Sullivan, R.B. D'Agostino, Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease. J. Clin. Endocrinol. Metab. 91, 2906-2912 (2006)
6. M.P. St-Onge, I. Janssen, S.B. Heymsfield, Metabolic syndrome in normal-weight Americans: new definition of the metabolically obese, normal-weight individual. Diabetes Care 27, 2222-2228 (2004)
7. N.B. Ruderman, D. Chisholm, X. Pi-Sunyer, S. Schneider, The metabolically obese, normal-weight individual revisited. Diabetes 47, 699-713 (1998)
8. E. Succurro, M.A. Marini, S. Frontoni, M.L. Hribal, F. Andreozzi, R. Lauro, F. Perticone, G. Sesti, Insulin secretion in metabolically obese, but normal weight, and in metabolically healthy but obese individuals. Obesity 16, 1881-1886 (2008)
9. E. Molero-Conejo, L.M. Morales, V. Fernández, X. Raleigh, M.E. Gómez, M. Semprún-Fereira, G. Campos, E. Ryder, Lean adolescents with increased risk for metabolic syndrome. Arch. Latinoam. Nutr. 53, 39-46 (2003)
10. B.H. Goodpaster, S. Krishnaswami, H. Resnick, D.E. Kelley, C. Haggerty, T.B. Harris, A.V. Schwartz, S. Kritchevsky, A.B. Newman, Association between regional adipose tissue distribution and both type 2 diabetes and impaired glucose tolerance in elderly men and women. Diabetes Care 26, 372-379 (2003)
11. K.M. Choi, H.J. Cho, H.Y. Choi, S.J. Yang, H.J. Yoo, J.A. Seo, S.G. Kim, S.H. Baik, D.S. Choi, N.H. Kim, Higher mortality in metabolically obese normal weight people than in metabolically healthy obese subjects in elderly Koreans. Clin. Endocrinol. (Oxf) 79, 364-370 (2013)
12. J.L. Shea, M.T. King, Y. Yi, W. Gulliver, G. Sun, Body fat percentage is associated with cardiometabolic dysregulation in BMI-defined normal weight subjects. Nutr. Metab. Cardiovasc. Dis. 22, 741-747 (2012)
13. R.P. Wildman, P. Muntner, K. Reynolds, A.P. McGinn, S. Rajpathak, J. Wylie-Rosett, M.R. Sowers, The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: prevalence and correlates of 2 phenotypes among the US population (NHANES 1999-2004). Arch. Intern. Med. 168, 1617-1624 (2008)
14. S. Wallerius, R. Rosmond, T. Ljung, G. Holm, P. Björntorp, Rise in morning saliva cortisol is associated with abdominal obesity in men: a preliminary report. J. Endocrinol. Invest. 26, 616-619 (2003)
15. D.I. Phillips, D.J. Barker, C.H. Fall, J.R. Seckl, C.B. Whorwood, P.J. Wood, B.R. Walker, Elevated plasma cortisol concentrations: a link between low birth weight and the insulin resistance syndrome? J. Clin. Endocrinol. Metab. 83, 757-760 (1998)
16. S.M. Smith, W.W. Vale, The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress. Dialogues Clin. Neurosci. 8, 383-395 (2006)
17. D. Savic, G. Knezevic, S. Damjanovic, Z. Spiric, G. Matic, The role of personality and traumatic events in cortisol levels-where does PTSD fit in? Psychoneuroendocrinology 37, 937-947 (2012)
18. M. Katan, M. Christ-Crain, The stress hormone copeptin: a new prognostic biomarker in acute illness. Swiss Med Wkly 24(140), w13101 (2010)
19. U. Saleem, M. Khaleghi, N.G. Morgenthaler, A. Bergmann, J. Struck, T.H. Mosley Jr, Kullo IJ: plasma carboxy-terminal provasopressin (copeptin): a novel marker of insulin resistance and metabolic syndrome. J. Clin. Endocrinol. Metab. 94, 2558-2564 (2009)
20. S. Enhörning, L. Bankir, N. Bouby, J. Struck, B. Hedblad, M. Persson, N.G. Morgenthaler, P.M. Nilsson, O. Melander, Copeptin, a marker of vasopressin, in abdominal obesity, diabetes and microalbuminuria: the prospective Malmö Diet and Cancer Study cardiovascular cohort. Int. J. Obes. (Lond) 37, 598-603 (2013)
21. S. Wüst, E.F. Van Rossum, I.S. Federenko, J.W. Koper, R. Kumsta, D.H. Hellhammer, Common polymorphisms in the glucocorticoid receptor gene are associated with adrenocortical responses to psychosocial stress. J. Clin. Endocrinol. Metab. 89, 565-573 (2004)
22. P. Barat, M. Duclos, B. Gatta, P. Roger, P. Mormede, M.P. Moisan, Corticosteroid binding globulin gene polymorphism influences cortisol driven fat distribution in obese women. Obes. Res. 13, 1485-1490 (2005)
23. M.G. Dobson, C.P. Redfern, N. Unwin, J.U. Weaver, The N363S polymorphism of the glucocorticoid receptor: potential contribution to central obesity in men and lack of association with other risk factors for coronary heart disease and diabetes mellitus. J. Clin. Endocrinol. Metab. 86, 2270-2274 (2001)
24. A.M. Ward, C.H. Fall, C.E. Stein, K. Kumaran, S.R. Veena, P.J. Wood, H.E. Syddall, D.I. Phillips, Cortisol and the metabolic syndrome in South Asians. Clin. Endocrinol. (Oxf) 58, 500-505 (2003)
25. P. Marin, N. Darin, T. Amemiya, B. Andersson, S. Jern, P. Bjorntorp, Cortisol secretion in relation to body fat distribution in obese premenopausal women. Metabolism 41, 882-886 (1992)
26. R. Pasquali, B. Anconetani, R. Chattat, M. Biscotti, G. Spinucci, F. Casimirri, V. Vicennati, Carcello Carcello A, Labate AM: hypothalamic-pituitary- adrenal axis activity and its relationship to the autonomic nervous system in women with visceral and subcutaneous obesity: effects of the corticotropin-releasing factor/arginine-vasopressin test and of stress. Metabolism 45, 351-356 (1996)
27. S.B. Abraham, D. Rubino, N. Sinaii, S. Ramsey, L.K. Nieman, Cortisol, obesity, and the metabolic syndrome: a cross-sectional study of obese subjects and review of the literature. Obesity (Silver Spring) 21, E105-E117 (2013)
28. E.F. van Rossum, J.W. Koper, A.W. van den Beld, A.G. Uitterlinden, P. Arp, W. Ester, J.A. Janssen, A.O. Brinkmann, F.H. de Jong, D.E. Grobbee, H.A. Pols, S.W. Lamberts, Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index. Clin. Endocrinol. (Oxf) 59, 585-592 (2003)
29. A. Stevens, D.W. Ray, E. Zeggini, S. John, H.L. Richards, C.E. Griffiths, R. Donn, Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype. J. Clin. Endocrinol. Metab. 89, 892-897 (2004)
30. R.C. Lin, X.L. Wang, B.J. Morris, Association of coronary artery disease with glucocorticoid receptor N363S variant. Hypertension 2003(41), 404-407 (2003)
31. A.M. Di Blasio, E.F. van Rossum, S. Maestrini, M.E. Berselli, M. Tagliaferri, F. Podestà, J.W. Koper, A. Liuzzi, S.W. Lamberts, The relation between two polymorphisms in the glucocorticoid receptor gene and body mass index, blood pressure and cholesterol in obese patients. Clin. Endocrinol. (Oxf) 59, 68-74 (2003)
32. K. Ahola, L. Pulkki-Råback, A. Kouvonen, H. Rossi, A. Aromaa, J. Lönnqvist, Burnout and behavior-related health risk factors: results from the population-based Finnish Health 2000 Study. J. Occup. Environ. Med. 54, 17-22 (2012)
33. E. Melcescu, M. Griswold, L. Xiang, S. Belk, D. Montgomery, M. Bray, K.S. Del Ben, G.I. Uwaifo, G.D. Marshall, C.A. Koch, Prevalence and cardiometabolic associations of the glucocorticoid receptor gene polymorphisms N363S and Bcl1 in obese and non-obese black and white Mississippians. Hormones (Athens) 11, 166-177 (2012)
34. S. Branth, G. Ronquist, M. Stridsberg, L. Hambraeus, E. Kindgren, R. Olsson, D. Carlander, B. Arnetz, Development of abdominal fat and incipient metabolic syndrome in young healthy men exposed to long-term stress. Nutr. Metab. Cardiovasc. Dis. 17, 427-435 (2007)
35. G. Bednarek Tupikowska, B. Stachowska, T. Miazgowski, B. Krzyżanowska-Świniarska, B. Katra, Evaluation of the prevalence of metabolic obesity and normal weight among the Polish population. Endokrynol. Pol. 63, 447-455 (2012)