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Volumn 22, Issue 17, 2014, Pages 4836-4847
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Structural optimization of a retrograde trafficking inhibitor that protects cells from infections by human polyoma- and papillomaviruses
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Author keywords
Dihydroquinazolinone; Papillomavirus; Polyomavirus; Retrograde trafficking; SAR
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Indexed keywords
2 (3 METHYLTHIOPHEN 2 YL) 3 PHENYL 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (4 METHYLTHIOPHEN 2 YL) 3 PHENYL 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 EHYLTHIOPHEN 2 YL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 (1 PHENYLETHYL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 (2 METHOXYBENZYL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 (3 FLUOROBENZYL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 (3 METHOXYBENZYL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 (3 NITROBENZYL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 (4 FLUOROBENZYL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 (4 FLUOROBENZYL) 5 METHYL 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 (4 FLUOROBENZYL) 6 METHYL 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 (4 FLUOROBENZYL) 7 METHYL 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 (4 METHOXYBENZYL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 (4 NITROBENZYL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 (NAPHTHALEN 1 YLMETHYL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 ISOPROPYL 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 PHENETHYL 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 PHENYL 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 ETHYLTHIOPHEN 2 YL) 3 PROPYL 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (5 METHYLFURAN 2 YL) 3 PHENYL 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (BENZO[B]THIOPHEN 2 YL) 3 PHENYL 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
2 (FURAN 2 YL) 3 PHENYL 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
3 (2,4 DIMETHOXYBENZYL) 2 (5 ETHYLTHIOPHEN 2 YL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
3 BENZYL 2 (5 ETHYLTHIOPHEN 2 YL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
3 BUTYL 2 (5 ETHYLTHIOPHEN 2 YL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
3 CYCLOHEXYL 2 (5 ETHYLTHIOPHEN 2 YL) 2,3 DIHYDOQUINAZOLIN 4(1H)ONE;
3 PHENYL 2 (1H PYRROL 2 YL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
ANTIVIRUS AGENT;
PHENYL 2 (THIOPHEN 2 YL) 2,3 DIHYDROQUINAZOLIN 4(1H) ONE;
UNCLASSIFIED DRUG;
UNINDEXED DRUG;
QUINAZOLINE DERIVATIVE;
ANTIVIRAL ACTIVITY;
ARTICLE;
CELL PROTECTION;
CONCENTRATION RESPONSE;
CONTROLLED STUDY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
IN VITRO STUDY;
NONHUMAN;
PAPILLOMA VIRUS;
PROCESS OPTIMIZATION;
STRUCTURE ACTIVITY RELATION;
VIRUS ENTRY;
CELL LINE;
CHEMICAL STRUCTURE;
CHEMISTRY;
DOSE RESPONSE;
DRUG EFFECTS;
HUMAN;
JC VIRUS;
NERVE CELL;
NERVE FIBER TRANSPORT;
PAPILLOMAVIRIDAE;
PHYSIOLOGY;
SYNTHESIS;
VIROLOGY;
BK POLYOMAVIRUS;
DNA VIRUSES;
HUMAN PAPILLOMAVIRUS TYPE 16;
JC POLYOMAVIRUS;
PAPILLOMAVIRIDAE;
POLYOMAVIRUS;
AXONAL TRANSPORT;
CELL LINE;
DOSE-RESPONSE RELATIONSHIP, DRUG;
HUMANS;
JC VIRUS;
MOLECULAR STRUCTURE;
NEURONS;
PAPILLOMAVIRIDAE;
QUINAZOLINES;
STRUCTURE-ACTIVITY RELATIONSHIP;
VIRUS INTERNALIZATION;
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EID: 84906936986
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2014.06.053 Document Type: Article |
Times cited : (37)
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References (24)
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