Design and synthesis of sulfamoyl benzoic acid analogues with subnanomolar agonist activity specific to the LPA2 receptor

Journal of Medicinal Chemistry

Volumn 57, Issue 16, 2014, Pages 7136-7140

  Patil, Renukadevi ^a   Fells, James I ^a   Szabó, Erzsébet ^a   Lim, Keng G ^a   Norman, Derek D ^a   Balogh, Andrea ^a   Patil, Shivaputra ^a   Strobos, Jur ^b   Miller, Duane D ^a   Tigyi, Gábor J ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b Rxbio Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOIC ACID DERIVATIVE; CARZENIDE; LYSOPHOSPHATIDIC ACID RECEPTOR;

AGONISTS; BINDING SITE; CHEMISTRY; DRUG DESIGN; HUMAN; METABOLISM; MOLECULAR DOCKING; PRECLINICAL STUDY; PROCEDURES; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

BENZOATES; BINDING SITES; CHEMISTRY TECHNIQUES, SYNTHETIC; DRUG DESIGN; DRUG EVALUATION, PRECLINICAL; HUMANS; MOLECULAR DOCKING SIMULATION; RECEPTORS, LYSOPHOSPHATIDIC ACID; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84906861082     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm5007116     Document Type: Article

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