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Volumn 43, Issue 5, 2014, Pages 681-686

Abnormal levels of brain metabolites may mediate cognitive impairment in stroke-free patients with cerebrovascular risk factors

Author keywords

Brain metabolites; Cognitive impairment; Framingham stroke risk profile

Indexed keywords

CHOLINE; CREATINE; GLUTAMIC ACID; GLUTAMINE; INOSITOL; N ACETYLASPARTIC ACID; BIOLOGICAL MARKER;

EID: 84906853489     PISSN: 00020729     EISSN: 14682834     Source Type: Journal    
DOI: 10.1093/ageing/afu027     Document Type: Article
Times cited : (11)

References (30)
  • 1
    • 77950263954 scopus 로고    scopus 로고
    • Prevalence of diabetes among men and women in China
    • Yang W, Lu J, Weng J et al. Prevalence of diabetes among men and women in China. N Engl J Med. 2010; 362: 1090-101.
    • (2010) N Engl J Med. , vol.362 , pp. 1090-1101
    • Yang, W.1    Lu, J.2    Weng, J.3
  • 2
    • 84874590461 scopus 로고    scopus 로고
    • Prevalence of hypertension in Chinese cities: a meta-analysis of published studies
    • Ma YQ, Mei WH, Yin P, Yang XH, Rastegar SK, Yan JD. Prevalence of hypertension in Chinese cities: a meta-analysis of published studies. PLoS ONE 2013; 8: e58302.
    • (2013) PLoS ONE , vol.8
    • Ma, Y.Q.1    Mei, W.H.2    Yin, P.3    Yang, X.H.4    Rastegar, S.K.5    Yan, J.D.6
  • 3
    • 82955210332 scopus 로고    scopus 로고
    • Vascular risk factors and cognitive impairment in a stroke-free cohort
    • Unverzagt FW, McClure LA, Wadley VG et al. Vascular risk factors and cognitive impairment in a stroke-free cohort. Neurology 2011; 77: 1729-36.
    • (2011) Neurology , vol.77 , pp. 1729-1736
    • Unverzagt, F.W.1    McClure, L.A.2    Wadley, V.G.3
  • 4
    • 33746462348 scopus 로고    scopus 로고
    • Cerebral blood flow velocity and periventricular white matter hyperintensities in type 2 diabetes
    • Novak V, Last D, Alsop DC et al. Cerebral blood flow velocity and periventricular white matter hyperintensities in type 2 diabetes. Diabetes Care 2006; 29: 1529-34.
    • (2006) Diabetes Care , vol.29 , pp. 1529-1534
    • Novak, V.1    Last, D.2    Alsop, D.C.3
  • 5
    • 8644272509 scopus 로고    scopus 로고
    • Stroke risk profile, brain volume, and cognitive function: the Framingham Offspring study
    • Seshadri S, Wolf PA, Beiser A et al. Stroke risk profile, brain volume, and cognitive function: the Framingham Offspring study. Neurology 2004; 63: 1591-9.
    • (2004) Neurology , vol.63 , pp. 1591-1599
    • Seshadri, S.1    Wolf, P.A.2    Beiser, A.3
  • 6
    • 39349089972 scopus 로고    scopus 로고
    • Abnormal regional cerebral blood flow in cognitively normal elderly subjects with hypertension
    • Dai W, Lopez OL, Carmichael OT, Becker JT, Kuller LH, Gach HM. Abnormal regional cerebral blood flow in cognitively normal elderly subjects with hypertension. Stroke. 2008; 39: 349-54.
    • (2008) Stroke. , vol.39 , pp. 349-354
    • Dai, W.1    Lopez, O.L.2    Carmichael, O.T.3    Becker, J.T.4    Kuller, L.H.5    Gach, H.M.6
  • 7
    • 70349973845 scopus 로고    scopus 로고
    • Met carriers of BDNF Val66Met genotype show increased N-acetylaspartate concentration in the anterior cingulate cortex
    • Gallinat J, Schubert F, Bruhl R et al. Met carriers of BDNF Val66Met genotype show increased N-acetylaspartate concentration in the anterior cingulate cortex. NeuroImage 2010; 49: 767-71.
    • (2010) NeuroImage , vol.49 , pp. 767-771
    • Gallinat, J.1    Schubert, F.2    Bruhl, R.3
  • 8
    • 0141595265 scopus 로고    scopus 로고
    • Glutamate and the glutamate receptor system: a target for drug action
    • Bleich S, Romer K, Wiltfang J, Kornhuber J. Glutamate and the glutamate receptor system: a target for drug action. Int J Geriatr Psych. 2003; 18(Suppl. 1): S33-40.
    • (2003) Int J Geriatr Psych. , vol.18 , Issue.SUPPL. 1
    • Bleich, S.1    Romer, K.2    Wiltfang, J.3    Kornhuber, J.4
  • 9
    • 79960212377 scopus 로고    scopus 로고
    • Vigorous exercise increases brain lactate and Glx (glutamate +glutamine): a dynamic 1H-MRS study
    • Maddock RJ, Casazza GA, Buonocore MH, Tanase C. Vigorous exercise increases brain lactate and Glx (glutamate +glutamine): a dynamic 1H-MRS study. NeuroImage 2011; 57: 1324-30.
    • (2011) NeuroImage , vol.57 , pp. 1324-1330
    • Maddock, R.J.1    Casazza, G.A.2    Buonocore, M.H.3    Tanase, C.4
  • 10
    • 0035664261 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy of the pediatric brain
    • Cecil KM, Jones BV. Magnetic resonance spectroscopy of the pediatric brain. Top Magn Reson Imaging 2001; 12: 435-52.
    • (2001) Top Magn Reson Imaging , vol.12 , pp. 435-452
    • Cecil, K.M.1    Jones, B.V.2
  • 11
    • 84875465982 scopus 로고    scopus 로고
    • Proton MRS in mild cognitive impairment
    • Kantarci K. Proton MRS in mild cognitive impairment. J Magn Reson Imaging 2013; 37: 770-7.
    • (2013) J Magn Reson Imaging , vol.37 , pp. 770-777
    • Kantarci, K.1
  • 12
    • 45849119076 scopus 로고    scopus 로고
    • Evaluation of in vivo cerebral metabolism on proton magnetic resonance spectroscopy in patients with impaired glucose tolerance and type 2 diabetes mellitus
    • Sahin I, Alkan A, Keskin L et al. Evaluation of in vivo cerebral metabolism on proton magnetic resonance spectroscopy in patients with impaired glucose tolerance and type 2 diabetes mellitus. J Diab Complic 2008; 22: 254-60.
    • (2008) J Diab Complic , vol.22 , pp. 254-260
    • Sahin, I.1    Alkan, A.2    Keskin, L.3
  • 13
    • 65549109399 scopus 로고    scopus 로고
    • Synergistic effect of cardiovascular risk factors on necrotic core in coronary arteries: a report from the global intravascular radiofrequency data analysis registry
    • Garcia-Garcia HM, Serruys PW, Mintz GS et al. Synergistic effect of cardiovascular risk factors on necrotic core in coronary arteries: a report from the global intravascular radiofrequency data analysis registry. J Am Coll Cardiol Img 2009; 2: 629-36.
    • (2009) J Am Coll Cardiol Img , vol.2 , pp. 629-636
    • Garcia-Garcia, H.M.1    Serruys, P.W.2    Mintz, G.S.3
  • 14
    • 0026064452 scopus 로고
    • Probability of stroke: a risk profile from the Framingham Study
    • Wolf PA, D'Agostino RB, Belanger AJ, Kannel WB. Probability of stroke: a risk profile from the Framingham Study. Stroke. 1991; 22: 312-8.
    • (1991) Stroke. , vol.22 , pp. 312-318
    • Wolf, P.A.1    D'Agostino, R.B.2    Belanger, A.J.3    Kannel, W.B.4
  • 15
    • 0027451907 scopus 로고
    • Development of the human brain: in vivo quantification of metabolite and water content with proton magnetic resonance spectroscopy
    • Kreis R, Ernst T, Ross BD. Development of the human brain: in vivo quantification of metabolite and water content with proton magnetic resonance spectroscopy. Magn Reson Med. 1993; 30: 424-37.
    • (1993) Magn Reson Med. , vol.30 , pp. 424-437
    • Kreis, R.1    Ernst, T.2    Ross, B.D.3
  • 16
    • 0344286501 scopus 로고    scopus 로고
    • Localized proton MRS of the human hippocampus: metabolite concentrations and relaxation times
    • Choi CG, Frahm J. Localized proton MRS of the human hippocampus: metabolite concentrations and relaxation times. Magn Reson Med. 1999; 41: 204-7.
    • (1999) Magn Reson Med. , vol.41 , pp. 204-207
    • Choi, C.G.1    Frahm, J.2
  • 17
    • 84877024880 scopus 로고    scopus 로고
    • Cardiovascular risk factors and cognitive decline in adults aged 50 and over: a population-based cohort study
    • Dregan A, Stewart R, Gulliford MC. Cardiovascular risk factors and cognitive decline in adults aged 50 and over: a population-based cohort study. Age Ageing. 2013; 42: 338-45.
    • (2013) Age Ageing. , vol.42 , pp. 338-345
    • Dregan, A.1    Stewart, R.2    Gulliford, M.C.3
  • 18
    • 84880171745 scopus 로고    scopus 로고
    • Cardiovascular risk profile and cognitive function in young, middle-aged, and elderly subjects
    • Joosten H, van Eersel ME, Gansevoort RT, Bilo HJ, Slaets JP, Izaks GJ. Cardiovascular risk profile and cognitive function in young, middle-aged, and elderly subjects. Stroke. 2013; 44: 1543-9.
    • (2013) Stroke. , vol.44 , pp. 1543-1549
    • Joosten, H.1    van Eersel, M.E.2    Gansevoort, R.T.3    Bilo, H.J.4    Slaets, J.P.5    Izaks, G.J.6
  • 19
    • 67349141556 scopus 로고    scopus 로고
    • Atherosclerosis Risk in Communities Study Brain MRIS. Fourteen-year longitudinal study of vascular risk factors, APOE genotype, and cognition: the ARIC MRI Study
    • Knopman DS, Mosley TH, Catellier DJ, Coker LH. Atherosclerosis Risk in Communities Study Brain MRIS. Fourteen-year longitudinal study of vascular risk factors, APOE genotype, and cognition: the ARIC MRI Study. Alzheimers Dement. 2009; 5: 207-14.
    • (2009) Alzheimers Dement. , vol.5 , pp. 207-214
    • Knopman, D.S.1    Mosley, T.H.2    Catellier, D.J.3    Coker, L.H.4
  • 20
    • 63449099901 scopus 로고    scopus 로고
    • Understanding memory dysfunction
    • Budson AE. Understanding memory dysfunction. The Neurologist 2009; 15: 71-9.
    • (2009) The Neurologist , vol.15 , pp. 71-79
    • Budson, A.E.1
  • 21
    • 79551635442 scopus 로고    scopus 로고
    • Framingham cardiovascular risk profile correlates with impaired hippocampal and cortical vasoreactivity to hypercapnia
    • Glodzik L, Rusinek H, Brys M et al. Framingham cardiovascular risk profile correlates with impaired hippocampal and cortical vasoreactivity to hypercapnia. J Cerebr Blood Flow Metab 2011; 31: 671-9.
    • (2011) J Cerebr Blood Flow Metab , vol.31 , pp. 671-679
    • Glodzik, L.1    Rusinek, H.2    Brys, M.3
  • 23
    • 3242761581 scopus 로고    scopus 로고
    • Stroke risk profile predicts white matter hyperintensity volume: the Framingham study
    • Jeerakathil T, Wolf PA, Beiser A et al. Stroke risk profile predicts white matter hyperintensity volume: the Framingham study. Stroke. 2004; 35: 1857-61.
    • (2004) Stroke. , vol.35 , pp. 1857-1861
    • Jeerakathil, T.1    Wolf, P.A.2    Beiser, A.3
  • 24
    • 32944475747 scopus 로고    scopus 로고
    • Association of white matter hyperintensity volume with decreased cognitive functioning: the Framingham Heart Study
    • Au R, Massaro JM, Wolf PA et al. Association of white matter hyperintensity volume with decreased cognitive functioning: the Framingham Heart Study. Arch Neurol. 2006; 63: 246-50.
    • (2006) Arch Neurol. , vol.63 , pp. 246-250
    • Au, R.1    Massaro, J.M.2    Wolf, P.A.3
  • 26
    • 79952816160 scopus 로고    scopus 로고
    • The impact of blood pressure on hippocampal glutamate and mnestic function
    • Westhoff TH, Schubert F, Wirth C et al. The impact of blood pressure on hippocampal glutamate and mnestic function. J Hum Hypertens 2011; 25: 256-61.
    • (2011) J Hum Hypertens , vol.25 , pp. 256-261
    • Westhoff, T.H.1    Schubert, F.2    Wirth, C.3
  • 27
    • 60549096743 scopus 로고    scopus 로고
    • Impact of fasting glycemia and regional cerebral perfusion in diabetic subjects: a study with technetium-99m-ethyl cysteinate dimer single photon emission computed tomography
    • Cosentino F, Battista R, Scuteri A et al. Impact of fasting glycemia and regional cerebral perfusion in diabetic subjects: a study with technetium-99m-ethyl cysteinate dimer single photon emission computed tomography. Stroke. 2009; 40: 306-8.
    • (2009) Stroke. , vol.40 , pp. 306-308
    • Cosentino, F.1    Battista, R.2    Scuteri, A.3
  • 29
    • 53949085542 scopus 로고    scopus 로고
    • Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: involvement of oxidative stress and mitogenactivated protein kinase cascades
    • Matos M, Augusto E, Oliveira CR, Agostinho P. Amyloid-beta peptide decreases glutamate uptake in cultured astrocytes: involvement of oxidative stress and mitogenactivated protein kinase cascades. Neuroscience 2008; 156: 898-910.
    • (2008) Neuroscience , vol.156 , pp. 898-910
    • Matos, M.1    Augusto, E.2    Oliveira, C.R.3    Agostinho, P.4
  • 30
    • 74349126815 scopus 로고    scopus 로고
    • Posterior paralimbic and frontal metabolite impairments in asymptomatic hypertension with different treatment outcomes
    • Garcia Santos JM, Fuentes LJ, Vidal JB et al. Posterior paralimbic and frontal metabolite impairments in asymptomatic hypertension with different treatment outcomes. Hypertens Res. 2010; 33: 67-75.
    • (2010) Hypertens Res. , vol.33 , pp. 67-75
    • Garcia Santos, J.M.1    Fuentes, L.J.2    Vidal, J.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.