Tanshinone IIA, a major component of Salvia milthorriza Bunge, inhibits platelet activation via Erk-2 signaling pathway

Journal of Ethnopharmacology

Volumn 155, Issue 2, 2014, Pages 1236-1242

  Maione, Francesco ^a   De Feo, Vincenzo ^b   Caiazzo, Elisabetta ^a   De Martino, Laura ^b   Cicala, Carla ^a   Mascolo, Nicola ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF SALERNO   (Italy)

Author keywords

Antiplatelet; Cardiovascular; Diterpenoids; Tanshinone IIA; Traditional chinese medicine

Indexed keywords

ADENOSINE DIPHOSPHATE; COLLAGEN; MITOGEN ACTIVATED PROTEIN KINASE 1; TANSHINONE IIA; TUBULIN; ABIETANE DERIVATIVE; ANTITHROMBOCYTIC AGENT; MAPK1 PROTEIN, RAT; PLANT EXTRACT; TANSHINONE;

ACETYLATION; ANIMAL EXPERIMENT; ARTICLE; BLEEDING TIME; BLOOD VISCOSITY; CELL LYSATE; CONTROLLED STUDY; DRUG EFFECT; ENZYME PHOSPHORYLATION; INTRACELLULAR SIGNALING; MALE; MICROCIRCULATION; NONHUMAN; PROTEIN EXPRESSION; RAT; SALVIA MILTIORRHIZA; SIGNAL TRANSDUCTION; THROMBOCYTE ACTIVATION; THROMBOCYTE AGGREGATION; THROMBOCYTE POOR PLASMA; THROMBOCYTE RICH PLASMA; ANIMAL; BLOOD CLOTTING PARAMETERS; CHEMISTRY; DOSE RESPONSE; DRUG EFFECTS; ENZYME ACTIVATION; ENZYMOLOGY; HEMOSTASIS; ISOLATION AND PURIFICATION; MEDICINAL PLANT; METABOLISM; MOUSE; PHOSPHORYLATION; PHYTOTHERAPY; PLANT ROOT; THROMBOCYTE; TIME; WISTAR RAT;

LAMIACEAE; MUS; RATTUS; SALVIA;

ACETYLATION; ANIMALS; BLEEDING TIME; BLOOD PLATELETS; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HEMOSTASIS; MALE; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 1; PHOSPHORYLATION; PHYTOTHERAPY; PLANT EXTRACTS; PLANT ROOTS; PLANTS, MEDICINAL; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET FUNCTION TESTS; RATS, WISTAR; SALVIA MILTIORRHIZA; SIGNAL TRANSDUCTION; TIME FACTORS; TUBULIN;

EID: 84906794344     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2014.07.010     Document Type: Article

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