CCL2 induction by 1,25(OH)2D3 in dendritic cells from healthy donors and multiple sclerosis patients

Journal of Steroid Biochemistry and Molecular Biology

Volumn 144, Issue PART A, 2014, Pages 102-105

  Sanseverino, Isabella ^a   Rinaldi, Arturo O ^a   Purificato, Cristina ^a   Cortese, Antonio ^b   Millefiorini, Enrico ^b   Gessani, Sandra ^a   Gauzzi, M Cristina ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

CCL2; Dendritic cell; Multiple sclerosis; Vitamin D

Indexed keywords

MONOCYTE CHEMOTACTIC PROTEIN 1; VITAMIN D; CALCIFEDIOL; CALCITRIOL;

ARTICLE; CELL MATURATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DENDRITIC CELL; HUMAN; HUMAN CELL; IMMUNOMODULATION; MONOCYTE; MULTIPLE SCLEROSIS; IMMUNE SYSTEM; PROTEIN EXPRESSION; PROTEIN SECRETION;

CCL2; DENDRITIC CELL; MULTIPLE SCLEROSIS; VITAMIN D;

BIOLOGICAL MARKERS; CALCITRIOL; CASE-CONTROL STUDIES; CHEMOKINE CCL2; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; VITAMINS;

EID: 84906790402     PISSN: 09600760     EISSN: 18791220     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2013.10.018     Document Type: Article

References (16)

1. A. Nylander, and D.A. Hafler Multiple sclerosis J. Clin. Invest. 122 2012 1180 1188
2. A. Ascherio, K.L. Munger, and J.D. Lunemann The initiation and prevention of multiple sclerosis Nat. Rev. Neurol. 8 2012 602 612
3. E. James, R. Dobson, J. Kuhle, D. Baker, G. Giovannoni, and S.V. Ramagopalan The effect of vitamin D-related interventions on multiple sclerosis relapses: A meta-analysis Mult. Scler. 19 2013 1571 1579
4. M. Hutchinson If I had CIS with MRI diagnostic of MS I would take vitamin D 10,000 IU daily: commentary Mult. Scler. 19 2013 143 144
5. L. Adorini, and G. Penna Control of autoimmune diseases by the vitamin D endocrine system Nat. Clin. Pract. Rheumatol. 4 2008 404 412
6. D.J. Mahad, and R.M. Ransohoff The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE) Semin. Immunol. 15 2003 23 32
7. M.F. Bachmann, M. Kopf, and B.J. Marsland Chemokines: more than just road signs Nat. Rev. Immunol. 6 2006 159 164
8. M. Del Corno, A. Michienzi, A. Masotti, L. Da Sacco, G.F. Bottazzo, F. Belardelli, and S. Gessani CC chemokine ligand 2 down-modulation by selected toll-like receptor agonist combinations contributes to T helper 1 polarization in human dendritic cells Blood 114 2009 796 806
9. L. Gu, S. Tseng, R.M. Horner, C. Tam, M. Loda, and B.J. Rollins Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1 Nature 404 2000 407 411
10. A. Nuyts, W. Lee, R. Bashir-Dar, Z. Berneman, and N. Cools Dendritic cells in multiple sclerosis: key players in the immunopathogenesis, key players for new cellular immunotherapies? Mult. Scler. 19 2013 995 1002
11. C.H. Polman, S.C. Reingold, B. Banwell, M. Clanet, J.A. Cohen, M. Filippi, K. Fujihara, E. Havrdova, M. Hutchinson, L. Kappos, F.D. Lublin, X. Montalban, P. O'Connor, M. Sandberg-Wollheim, A.J. Thompson, E. Waubant, B. Weinshenker, and J.S. Wolinsky Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria Ann. Neurol. 69 2011 292 302
12. M. Yang, Z. Shen, D. Chen, H. Gan, Q. Shen, B. Yang, and X. Du Effects of 1,25-(OH)(2)D (3) on the expressions of vitamin D receptor, STAT5 and cytoskeletal rearrangement in human monocytes incubated with sera from type 2 diabetes patients and diabetic nephropathy patients with uremia Inflamm. Res. 61 2012 511 520
13. P. Selvaraj, M. Harishankar, B. Singh, V.V. Banurekha, and M.S. Jawahar Effect of vitamin D3 on chemokine expression in pulmonary tuberculosis Cytokine 60 2012 212 219
14. K.J. Zhu, Q.Y. Shen, M. Zheng, and U. Mrowietz Effects of calcitriol and its analogues on interaction of MCP-1 and monocyte derived dendritic cells in vitro Acta Pharmacol. Sin. 22 2001 62 65
15. M. Hewison Vitamin D and the immune system: new perspectives on an old theme Endocrinol. Metab. Clin. North Am. 39 2010 365 379
16. D. Sagar, A. Lamontagne, C.A. Foss, Z.K. Khan, M.G. Pomper, and P. Jain Dendritic cell CNS recruitment correlates with disease severity in EAE via CCL2 chemotaxis at the blood-brain barrier through paracellular transmigration and ERK activation J. Neuroinflammation 9 2012 245 259