Managing the patent ductus arteriosus: Current treatment options

Archives of Disease in Childhood: Fetal and Neonatal Edition

Volumn 99, Issue 5, 2014, Pages

  Heuchan, Anne Marie ^a   Clyman, Ronald I ^b  

^a ROYAL HOSPITAL FOR SICK CHILDREN   (United Kingdom)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROSTAGLANDIN H2 SYNTHASE INHIBITOR; PROSTAGLANDIN SYNTHASE INHIBITOR; UNCLASSIFIED DRUG;

CATHETERIZATION; CLINICAL TRIAL (TOPIC); ECHOCARDIOGRAPHY; GESTATIONAL AGE; HUMAN; LIGATION; PATENT DUCTUS ARTERIOSUS; PATIENT ASSESSMENT; PATIENT CARE; PREMATURITY; PRIORITY JOURNAL; PROPHYLAXIS; REVIEW; DUCTUS ARTERIOSUS, PATENT; ECHOGRAPHY; HEART CATHETERIZATION; INFANT, PREMATURE, DISEASES; NEWBORN; PROCEDURES;

CARDIAC CATHETERIZATION; CYCLOOXYGENASE INHIBITORS; DUCTUS ARTERIOSUS, PATENT; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, PREMATURE, DISEASES; LIGATION;

EID: 84906790392     PISSN: 13592998     EISSN: 14682052     Source Type: Journal    
DOI: 10.1136/archdischild-2014-306176     Document Type: Review

References (61)

1. Bose CL, Laughon MM. Patent ductus arteriosus: lack of evidence for common treatments Arch. Dis Child Fetal Neonatal, Ed. 2007;92:F498-502. (Pubitemid 350063851)
2. Benitz WE. Patent ductus arteriosus: to treat or not to treat? Arch Dis Child Fetal Neonatal, Ed. 2012;97:F80-2.
3. Clyman RI, Marayanan M. Patent ductus arteriosus: a physiological basis for current treatment practices. Current Topics in Neonatology. 4th edn. Hansen, TN: McIntosh N. W.B. Saunders Company, 2000.
4. Gentile R, Stevenson G, Dooley T, et al. Doppler echocardiographic determination of time of ductal closure in normal newborn infants. J Pediatr 1981;98:443-8. (Pubitemid 11106256)
5. Reller MD, Rice MJ, McDonald RW. Review of studies evaluating ductal patency in the premature infant. J Pediatr 1993;122:S59-62. (Pubitemid 23158408)
6. Madan JC, Kendrick D, Hagadorn JI, et al. National Institute of Child Health and Human Development Neonatal Research Network. Patent ductus arteriosus therapy: impact on neonatal and 18-month outcome. Pediatrics 2009;123:674-81.
7. Koch J, Hensley G, Roy L, et al. Prevalence of spontaneous closure of the ductus arteriosus in neonates at a birth weight of 1000 grams or less. Pediatrics 2006;117:1113-21. (Pubitemid 46071502)
8. Clyman RI, Ballard PL, Sniderman S, et al. Prenatal administration of betamethasone for prevention of patient ductus arteriosus. J Pediatr 1981;98:123-6. (Pubitemid 11184078)
9. Narayanan M, Cooper B, Weiss H, et al. Prophylactic indomethacin: factors determining permanent ductus arteriosus closure. J Pediatr 2000;136:330-7. (Pubitemid 30470955)
10. Nemerofsky SL, Parravicini E, Bateman D, et al. The ductus arteriosus rarely requires treatment in infants >1000 grams. Am J Perinatol 2008;25:661-6.
11. Marshall DD, Kotelchuck M, Young TE, et al. Risk factors for chronic lung disease in the surfactant era: a North Carolina population-based study of very low birth weight infants. North Carolina Neonatologists Association. Pediatrics 1999;104:1345-50.
12. Brown ER. Increased risk of bronchopulmonary dysplasia in infants with patent ductus arteriosus. J Pediatr 1979;95:865-6. (Pubitemid 10209777)
13. Sarkar S, Dechert R, Schumacher RE. Is refractory hypotension in preterm infants a manifestation of early ductal shunting? J. Perinatol 2007;27:353-8. (Pubitemid 46860528)
14. Garland J, Buck R, Weinberg M. Pulmonary hemorrhage risk in infants with a clinically diagnosed patent ductus arteriosus: a retrospective cohort study. Pediatrics 1994;94:719-23. (Pubitemid 24326512)
15. Kluckow M, Evans N. Ductal shunting, high pulmonary blood flow, and pulmonary hemorrhage. J Pediatr 2000;137:68-72. (Pubitemid 30470925)
16. Evans N, Kluckow M. Early ductal shunting and intraventricular haemorrhage in ventilated preterm infants. Arch Dis Child Fetal Neonatal, Ed. 1996;75:F183-6. (Pubitemid 126439147)
17. Dollberg S, Lusky A, Reichman B. Patent ductus arteriosus, indomethacin and necrotizing enterocolitis in very low birth weight infants: a population-based study. J Pediatr Gastroenterol Nutr 2005;40:184-8. (Pubitemid 40269740)
18. Lemmers PM, Toet MC, van Bel F. Impact of patent ductus arteriosus and subsequent therapy with indomethacin on cerebral oxygenation in preterm infants. Pediatrics 2008;121:142-7.
19. McCurnin D, Seidner S, Chang LY, et al. Ibuprofen-induced patent ductus arteriosus closure: physiologic, histologic, and biochemical effects on the premature lung. Pediatrics 2008;121:945-56.
20. Clyman RI. Recommendations for the postnatal use of indomethacin: an analysis of four separate treatment strategies. J Pediatr 1996;128:601-7. (Pubitemid 26137716)
21. Cassady G, Crouse DT, Kirklin JW, et al. A randomized, controlled trial of very early prophylactic ligation of the ductus arteriosus in babies who weighed 1000 g or less at birth. N Engl J Med 1989;320:1511-696.
22. Cotton RB, Stahlman MT, Bender HW, et al. Randomized trial of early closure of symptomatic patent ductus arteriosus in small preterm infants. J Pediatr 1978;93:647-5.
23. Brooks JM, Travadi JN, Patole SK, et al. Is surgical ligation of patent ductus arteriosus necessary? The Western Australian experience of conservative management. Arch Dis Child Fetal Neonatal, Ed . 2005;90:F235-9.
24. Shah SS, Ohlsson A. Ibuprofen for the prevention of patent ductus arteriosus in preterm and/or low birth weight infants. Cochrane Database Syst Rev 2006; CD004213.
25. Fowlie PW, Davis PG, McGuire W. Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants. Cochrane Database Syst Rev 2010;CD000174.
26. Heuchan AM, Young D. Early colour Doppler duct diameter and symptomatic patent ductus arteriosus in a cyclo-oxygenase inhibitor naïve population. Acta Paediatr 2013;102:254-7.
27. Kluckow M, Evans N. Early echocardiographic prediction of symptomatic patent ductus arteriosus in preterm infants undergoing mechanical ventilation. J Pediatr 1995;127:774-9.
28. El Hajjar M, Vaksmann G, Rakza T, et al. Severity of the ductal shunt: a comparison of different markers. Arch Dis Child Fetal Neonatal, Ed. 2005;90:F419-22. (Pubitemid 41224079)
29. Sehgal A, McNamara PJ. Does echocardiography facilitate determination of hemodynamic significance attributable to the ductus arteriosus? Eur. J Pediatr 2009;168:907-14.
30. Evans N. Diagnosis of the preterm patent ductus arteriosus: clinical signs, biomarkers, or ultrasound? Sem. Perinatol 2012;36:114.
31. Jones LJ, Craven PD, Attia J, et al. Network meta-analysis of indomethacin versus ibuprofen versus placebo for PDA in preterm infants. Arch Dis Child Fetal Neonatal, Ed. 2011;96:F45-52.
32. Desfrere L, Zohar S, Morville P, et al. Dose- finding study of ibuprofen in patent ductus arteriosus using the continual reassessment method. J Clin Pharm Ther 2005;30:121-32. (Pubitemid 41583606)
33. Ohlsson A, Walia R, Shah SS. Ibuprofen for the treatment of patent ductus arteriosus in preterm and/or low birth weight infants. Cochrane Database Syst Rev 2013;4:CD003481.
34. Dani C, Vangi V, Bertini G, et al. High-dose ibuprofen for patent ductus arteriosus in extremely preterm infants: a randomized controlled study. Clin Pharmacol Ther 2012;91:590-6.
35. Erdeve O, Yurttutan S, Altug N, et al. Oral versus intravenous ibuprofen for patent ductus arteriosus closure: a randomised controlled trial in extremely low birthweight infants. Arch Dis Child Fetal Neonatal 2012;97:F279-83.
36. Neumann R, Schulzke SM, Buhrer C. Oral ibuprofen versus intravenous ibuprofen or intravenous indomethacin for the treatment of patent ductus arteriosus in preterm infants: a systematic review and meta-analysis. Neonatology 2012;102:9-15.
37. Carmo KB, Evans N, Paradisis M. Duration of indomethacin treatment of the preterm patent ductus arteriosus as directed by echocardiography. J Pediatr 2009;155:819-22.e1.
38. Attridge JT, Clark R, Walker MW, et al. New insights into spontaneous intestinal perforation using a national data set: SIP is associated with early indomethacin exposure. J Perinatol 2006;26:93-9.
39. Hammerman C, Bin-Nun A, Markovitch E, et al. Ductal closure with paracetamol: a surprising new approach to patent ductus arteriosus treatment. Pediatrics 2011;128:e1618-21.
40. Oncel MY, Yurttutan S, Degirmencioglu H, et al. Intravenous paracetamol treatment in the management of patent ductus arteriosus in extremely low birth weight infants. Neonatology 2012;103:166-9.
41. Alfaleh K, Smyth JA, Roberts RS, et al. Prevention and 18-month outcomes of serious pulmonary hemorrhage in extremely low birth weight infants: results from the trial of indomethacin prophylaxis in preterms. Pediatrics 2008;121:e233-8. (Pubitemid 351198427)
42. Schmidt B, Davis P, Moddemann D, et al. Long-term effects of indomethacin prophylaxis in extremely-low-birth-weight infants. N Engl J Med 2001;344:1966-72. (Pubitemid 32568150)
43. Ment LR, Vohr BR, Makuch RW, et al. Prevention of intraventricular hemorrhage by indomethacin in male preterm infants. J Pediatr 2004;145:832-4. (Pubitemid 39586624)
44. Cooke L, Steer P, Woodgate P. Indomethacin for asymptomatic patent ductus arteriosus in preterm infants. Cochrane Database Syst Rev 2003;0:CD003745.
45. Kluckow M, Jeffery M, Gill A, et al. A randomised placebo-controlled trial of early treatment of the patent ductus arteriosus. Arch Dis Child Fetal Neonatal, Ed. 2014;99:F99-104.
46. Kaempf JW, Wu YX, Kaempf AJ, et al. What happens when the patent ductus arteriosus is treated less aggressively in very low birth weight infants? J Perinatol 2012;32:344-8.
47. Sosenko IR, Fajardo MF, Claure N, et al. Timing of patent ductus arteriosus treatment and respiratory outcome in premature infants: a double-blind randomized controlled trial. J Pediatr 2012;160:929-35.
48. Heuchan AM, Hunter L, Young D. Outcomes following the surgical ligation of the patent ductus arteriosus in premature infants in Scotland. Arch Dis Child Fetal Neonatal, Ed. 2012;97:F39-44.
49. Szymankiewicz M, Hodgman JE, Siassi B, et al. Mechanics of breathing after surgical ligation of patent ductus arteriosus in newborns with respiratory distress syndrome. Biol Neonate 2004;85:32-6. (Pubitemid 38437645)
50. Teixeira LS, Shivananda SP, Stephens D, et al. Postoperative cardiorespiratory instability following ligation of the preterm ductus arteriosus is related to early need for intervention. J Perinatol 2008;28:803-10.
51. Patel N, Heuchan AM. Transient global left ventricular dysfunction after PDA ligation in preterm infants. J Paediatr Child Health 2012;48(Suppl. 1):128.
52. Clyman RI, Wickremasinghe A, Merritt TA, et al. Hypotension following patent ductus arteriosus ligation: the role of adrenal hormones. J Pediatr doi:10.1016/j.jpeds.2014.01.058.
53. Lemmers PM, Molenschot MC, Evens J, et al . Is cerebral oxygen supply compromised in preterm infants undergoing surgical closure for patent ductus arteriosus? Arch Dis Child Fetal Neonatal, Ed. 2010;95:F429-34.
54. Kabra NS, Schmidt B, Roberts RS, et al. Neurosensory impairment after surgical closure of patent ductus arteriosus in extremely low birth weight infants: results from the Trial of Indomethacin Prophylaxis in Preterms. J Pediatr 2007;150:229-34.e1.
55. McNamara J, Sehgal A. Towards rational management of the patent ductus arteriosus: the need for disease staging. Arch Dis Child Fetal Neonatal, Ed. 2007;92:F424-7. (Pubitemid 350043994)
56. Chang LY, McCurnin D, Yoder B, et al. Ductus arteriosus ligation and alveolar growth in preterm baboons with a patent ductus arteriosus. Pediatr Res 2008;63:299-302. (Pubitemid 351301460)
57. Waleh N, McCurnin DC, Yoder BA, et al. Patent ductus arteriosus ligation alters pulmonary gene expression in preterm baboons. Pediatr Res 2011;69:212-16.
58. Jhaveri N, Moon-Grady A, Clyman RI. Early surgical ligation versus a conservative approach for management of patent ductus arteriosus that fails to close after indomethacin treatment. J Pediatr 2010;157:381-7.
59. Mitchell J, Burns J, Heuchan AM. Transcatheter closure of PDA in ex-preterm infants in Scotland 2001-2010. Proceedings of the Annual Autumn Meeting of Paediatricians with Expertise in Cardiology Special Interest Group, Royal College of Physicians of Edinburgh, UK, 19th November 2013.
60. Roberts P, Adwani S, Archer N, et al . Catheter closure of the arterial duct in preterm infants. Arch Dis Child Fetal Neonatal, Ed. 2007;92:F248-50. (Pubitemid 47012986)
61. Clyman RI, Couto J, Murphy GM. Patent ductus arteriosus: are current neonatal treatment options better or worse than no treatment at all? Semin Perinatol 2012;36:123-9.