Metastasis-suppressor transcript destabilization through TARBP2 binding of mRNA hairpins

Nature

Volumn 513, Issue 7517, 2014, Pages 256-260

  Goodarzi, Hani ^a   Zhang, Steven ^a   Buss, Colin G ^a   Fish, Lisa ^a   Tavazoie, Saeed ^b   Tavazoie, Sohail F ^a  

^a ROCKEFELLER UNIVERSITY   (United States)

^b Och Spine at New York Presbyterian Hospitals   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PRECURSOR PROTEIN; RNA BINDING PROTEIN; ZINC FINGER PROTEIN; APP PROTEIN, HUMAN; DNA BINDING PROTEIN; MESSENGER RNA; TRANS ACTIVATION RESPONSIVE RNA BINDING PROTEIN; TRANS-ACTIVATION RESPONSIVE RNA-BINDING PROTEIN; TRANSCRIPTION FACTOR; ZNF395 PROTEIN, HUMAN;

BIOCHEMISTRY; CANCER; COLONIZATION; DISEASE INCIDENCE; GENE EXPRESSION; GERM CELL; MAMMAL; PEPTIDE; PROTEIN; RNA;

ARTICLE; BINDING SITE; BREAST CANCER; CANCER CELL; CANCER GROWTH; CELL INVASION; CONTROLLED STUDY; DNA BASE COMPOSITION; GENE EXPRESSION; GENE EXPRESSION REGULATION; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; METASTASIS; METASTASIS FREE SURVIVAL; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN SECONDARY STRUCTURE; RNA BINDING; RNA INTERFERENCE; RNA SEQUENCE; RNA STABILITY; RNA STRUCTURE; SUPPRESSOR GENE; TARBP2 GENE; ULTRAVIOLET RADIATION; BREAST TUMOR; FEMALE; GENE EXPRESSION PROFILING; GENETICS; HEK293 CELL LINE; METABOLISM; PATHOLOGY; PROTEIN BINDING; TUMOR CELL LINE;

MAMMALIA;

AMYLOID BETA-PROTEIN PRECURSOR; BREAST NEOPLASMS; CELL LINE, TUMOR; DNA-BINDING PROTEINS; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HUMANS; NEOPLASM METASTASIS; PROTEIN BINDING; RNA STABILITY; RNA, MESSENGER; RNA-BINDING PROTEINS; TRANSCRIPTION FACTORS;

EID: 84906710748     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature13466     Document Type: Article

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