Silver nanoparticle-coated suture effectively reduces inflammation and improves mechanical strength at intestinal anastomosis in mice

Journal of Pediatric Surgery

Volumn 49, Issue 4, 2014, Pages 606-613

  Zhang, Shiwei ^a   Liu, Xuelai ^b   Wang, Hualong ^a   Peng, Jiao ^a   Wong, Kenneth K Y ^b  

^a Department of Surgery Harbin Children Hospital ^*  (China)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

Anastomosis; Anti inflammatory; Healing; Silver nanoparticles; Sutures

Indexed keywords

ABSORBABLE SUTURE MATERIAL; ANTIBIOTIC AGENT; SILVER NANOPARTICLE; ANTIINFECTIVE AGENT; ANTIINFLAMMATORY AGENT; NANOPARTICLE; SILVER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; ESCHERICHIA COLI; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INTESTINE ANASTOMOSIS; MOUSE; NANOTECHNOLOGY; NONHUMAN; POLYGLACTIN SUTURE; PRESSURE MEASUREMENT; PRIORITY JOURNAL; SCANNING ELECTRON MICROSCOPY; SUTURE; TENSILE STRENGTH; WOUND DRESSING; WOUND HEALING; ANASTOMOSIS; ANIMAL; BIOMECHANICS; C57BL MOUSE; DEVICES; DRUG DELIVERY SYSTEM; DRUG EFFECTS; EVALUATION STUDY; ILEUM; POSTOPERATIVE COMPLICATIONS; PROCEDURES; RANDOMIZATION; SURGERY; TREATMENT OUTCOME;

ANASTOMOSIS, SURGICAL; ANIMALS; ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS; BIOMECHANICAL PHENOMENA; DRUG DELIVERY SYSTEMS; ESCHERICHIA COLI; ILEUM; INFLAMMATION; MICE; MICE, INBRED C57BL; NANOPARTICLES; POSTOPERATIVE COMPLICATIONS; RANDOM ALLOCATION; SILVER; SUTURES; TREATMENT OUTCOME; WOUND HEALING;

EID: 84906654889     PISSN: 00223468     EISSN: 15315037     Source Type: Journal    
DOI: 10.1016/j.jpedsurg.2013.12.012     Document Type: Article

References (29)

1. K.K.Y. Wong, and X. Liu Silver nanoparticles - the real "silver bullet" in clinical medicine? Med Chem Commun 1 2010 125 131
2. J.R. Morones, J.L. Elechiguerra, and A. Camacho et al. The bactericidal effect of silver nanoparticles Nanotechnology 16 2005 2346 2353
3. C.N. Lok, C.M. Ho, and R. Chen et al. Proteomic analysis of the mode of antibacterial action of silver nanoparticles J Proteome Res 5 2006 916 924
4. J.S. Kim, E. Kuk, and K.N. Yu et al. Antimicrobial effects of silver nanoparticles Nanomedicine 3 2007 95 101
5. M. Rai, A. Yadav, and A. Gade Silver nanoparticles as a new generation of antimicrobials Biotechnol Adv 27 2009 76 83
6. J. Tian, K.K. Wong, and C.M. Ho et al. Topical delivery of silver nanoparticles promotes wound healing ChemMedChem 2 2007 129 136
7. K.K. Wong, S.O. Cheung, and L. Huang et al. Further evidence of the anti-inflammatory effects of silver nanoparticles ChemMedChem 4 2009 1129 1135
8. J.B. Wright, K. Lam, and A.G. Buret et al. Early healing events in a porcine model of contaminated wounds: effects of nanocrystalline silver on matrix metalloproteinases, cell apoptosis, and healing Wound Repair Regen 10 2002 141 151
9. K.C. Bhol, and P.J. Schechter Effects of nanocrystalline silver (NPI 32101) in a rat model of ulcerative colitis Dig Dis Sci 52 2007 2732 2742
10. R.G. Sibbald, J. Contreras-Ruiz, and P. Coutts et al. Bacteriology, inflammation, and healing: a study of nanocrystalline silver dressings in chronic venous leg ulcers Adv Skin Wound Care 20 2007 549 558
11. P.L. Nadworny, J.F. Wang, and E.E. Tredget et al. Antiinflammatory activity of nanocrystalline silver in a porcine contact dermatitis model Nanomedicine: NBM 4 2008 241 251
12. S. Saxena, A.R. Ray, and A. Kapil et al. Development of a new polypropylene-based suture: plasma grafting, surface treatment, characterization, and biocompatibility studies Macromol Biosci 11 2011 373 382
13. S. Rothenburger, D. Spangler, and S. Bhende et al. In vitro evaluation of coated VICRYL Plus antibacterial suture (coated polyglactin 910 with triclosan) using zone of inhibition assays Surg Infect (Larchmt) 3 2002 S79 S87
14. H.R. Ford, P. Jones, and B. Gaines et al. Intraoperative handling and wound healing: controlled clinical trial comparing coated VICRYL plus antibacterial suture (coated polyglactin 910 suture with triclosan) with coated VICRYL suture (coated polyglactin 910 suture Surg Infect (Larchmt) 6 3 2005 313 321
15. C. Mingmalairak, P. Ungbhakorn, and V. Paocharoen Efficacy of antimicrobial coating suture coated polyglactin 910 with tricosan (Vicryl plus) compared with polyglactin 910 (Vicryl) in reduced surgical site infection of appendicitis, double blind randomized control trial, preliminary safety report J Med Assoc Thai 92 6 2009 770 775
16. S.T. Dubas, P. Kumlangdudsana, and P. Potiyaraj Layer-by-layer deposition of antimicrobial silver nanoparticles on textile fibers Colloids Surf A Physicochem Eng Asp 289 2006 105 109
17. K. Madhumathi, P.T. Sudheesh Kumar, and S. Abhilash et al. Development of novel chitin/nanosilver composite scaffolds for wound dressing applications J Mater Sci Mater Med 21 2010 807 813
18. R. Scaffaro, L. Botta, and M. Sanfilippo et al. Combining in the melt physical and biological properties of poly(caprolactone) and chlorhexidine to obtain antimicrobial surgical monofilaments Appl Microbiol Biotechnol 97 2013 99 109
19. M. Binnebösel, K. Junge, and D.A. Kaemmer et al. Intraperitoneally applied gentamicin increases collagen content and mechanical stability of colon anastomosis in rats Int J Colorectal Dis 24 2009 433 440
20. D.A. Kaemmer, J. Otto, and M. Binneboesel et al. Erythropoietin (EPO) influences colonic anastomotic healing in a rat model by modulating collagen metabolism J Surg Res 163 2010 e67 e72
21. P.A. Holzner, B. Kulemann, and S. Kuesters et al. Impact of remote ischemic preconditioning on wound healing in small bowel anastomoses World J Gastroenterol 17 2011 1308 1316
22. P. Muangman, C. Chuntrasakul, and S. Silthram et al. Comparison of efficacy of 1% silver sulfadiazine and Acticoat for treatment of partial-thickness burn wounds J Med Assoc Thai 89 7 2006 953 958
23. R.P. Varas, T. O'Keeffe, and N. Namias et al. A prospective, randomized trial of Acticoat versus silver sulfadiazine in the treatment of partial-thickness burns: which method is less painful? J Burn Care Rehabil 26 4 2005 344 347
24. X. Liu, P.Y. Lee, and C.M. Ho et al. Silver nanoparticles mediate differential responses in keratinocytes and fibroblasts during skin wound healing ChemMedChem 5 2010 468 475
25. K.H. Kwan, X. Liu, and M.K. To et al. Modulation of collagen alignment by silver nanoparticles results in better mechanical properties in wound healing Nanomedicine: NBM 7 2011 497 504
26. K.K.Y. Wong, and X.L. Liu Nanomedicine: a primer for surgeons Pediatr Surg Int 28 2012 943 951
27. J.W. Alexander, J.Z. Kaplan, and W.A. Altemeier Role of suture materials in the development of wound infection Ann Surg 165 1967 192 199
28. S. Katz, M. Izhar, and D. Mirelman Bacterial adherence to surgical sutures. A possible factor in suture induced infection Ann Surg 194 1981 235
29. C. Justinger, J. Schuld, and J. Sperling et al. Triclosan-coated sutures reduce wound infections after hepatobiliary surgery-a prospective non-randomized clinical pathway driven study Langenbecks Arch Surg 396 2011 845 850