Insulin protects pancreatic acinar cells from palmitoleic acid-induced cellular injury

Journal of Biological Chemistry

Volumn 289, Issue 34, 2014, Pages 23582-23595

  Samad, Aysha ^a   James, Andrew ^a   Wong, James ^a   Mankad, Parini ^a   Whitehouse, John ^a   Patel, Waseema ^a   Alves Simoes, Marta ^a   Siriwardena, Ajith K ^b   Bruce, Jason I E ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b MANCHESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; ETHANOL; INSULIN; METABOLISM; PHYSIOLOGY; UNSATURATED FATTY ACIDS;

ACUTE PANCREATITIS; CELLULAR INJURY; COLLAGENASE DIGESTION; INFLAMMATORY DISEASE; MITOCHONDRIAL METABOLISM; PALMITOLEIC ACID; PANCREATIC ACINAR CELLS; PROTECTIVE EFFECTS;

CALCIUM;

2 MORPHOLINO 8 PHENYLCHROMONE; ADENOSINE TRIPHOSPHATE; ALCOHOL; ESTER; INSULIN; PALMITOLEIC ACID; PALMITOLEIC ACID ETHYL ESTER; PLASMA MEMBRANE CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CALCIUM; CHROMONE DERIVATIVE; FATTY ACID; MONOUNSATURATED FATTY ACID; MORPHOLINE DERIVATIVE;

ACINAR CELL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM ION OVERLOAD; CELL DAMAGE; CELL DEATH; CELL PROTECTION; CLEARANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; INTOXICATION; INTRACELLULAR CALCIUM ION CONCENTRATION CLEARANCE ASSAY; METABOLIC ACTIVITY ASSAY; MOLECULAR PATHOLOGY; NONHUMAN; PANCREATITIS; PRIORITY JOURNAL; PROTEIN DEPLETION; RAT; ANIMAL; CYTOLOGY; DRUG EFFECTS; FLUORESCENCE; METABOLISM; PANCREAS; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADENOSINE TRIPHOSPHATE; ANIMALS; CALCIUM; CELL DEATH; CHROMONES; ETHANOL; FATTY ACIDS; FATTY ACIDS, MONOUNSATURATED; FLUORESCENCE; INSULIN; MORPHOLINES; PANCREAS; PLASMA MEMBRANE CALCIUM-TRANSPORTING ATPASES; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84906546260     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.589440     Document Type: Article

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