Hemolysis during cardiac surgery is associated with increased intravascular nitric oxide consumption and perioperative kidney and intestinal tissue damage

Frontiers in Physiology

Volumn 5 AUG, Issue , 2014, Pages

  Vermeulen Windsant, Iris C ^a,b   de Wit, Norbert C J ^a   Sertorio, Jonas T C ^c   van Bijnen, Annemarie A ^a   Ganushchak, Yuri M ^a   Heijmans, John H ^a   Tanus Santos, Jose E ^c   Jacobs, Michael J ^a,d   Maessen, Jos G ^a,d   Buurman, Wim A ^a,e  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b CATHARINA HOSPITAL   (Netherlands)

^c UNIVERSITY OF SÃO PAULO   (Brazil)

^d MAASTRICHT UNIVERSITY   (Netherlands)

^e MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Acute kidney injury; Cardiopulmonary bypass; Hemolysis; Intestinal fatty acid binding protein; Nitric oxide

Indexed keywords

FATTY ACID BINDING PROTEIN; HAPTOGLOBIN; HEMOGLOBIN; N ACETYL BETA GLUCOSAMINIDASE; NITRIC OXIDE; FATTY ACID BINDING PROTEIN 2;

ACUTE KIDNEY FAILURE; ADULT; AGED; ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; FEMALE; HEART SURGERY; HEART VALVE SURGERY; HEMOGLOBIN BLOOD LEVEL; HUMAN; INTESTINE INJURY; INTRAVASCULAR HEMOLYSIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OFF PUMP SURGERY; PERIOPERATIVE PERIOD; PILOT STUDY; THORAX SURGERY; TREATMENT OUTCOME; AREA UNDER THE CURVE; BIOAVAILABILITY; BLEEDING; CAUSE OF DEATH; CLINICAL ARTICLE; DISEASE ASSOCIATION; ENTEROPATHY; GASTROINTESTINAL MUCOSAL DISCOLORATION; HEART EJECTION FRACTION; HEMOLYSIS; ILEUS; INTESTINE ISCHEMIA; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY TUBULE DISORDER; MORTALITY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; OFF PUMP CORONARY SURGERY; ON PUMP CORONARY ARTERY BYPASS GRAFTING; PATHOGENESIS; PEROPERATIVE COMPLICATION; POSTOPERATIVE COMPLICATION; PROTEIN BLOOD LEVEL; PROTEIN DEPLETION; RESPIRATORY FAILURE; VERY ELDERLY;

EID: 84906495592     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2014.00340     Document Type: Article

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