Mixed effects of deep brain stimulation on depressive symptomatology in Parkinson's disease: A review of randomized clinical trials

Frontiers in Neurology

Volumn 5 AUG, Issue , 2014, Pages

  Gökbayrak, N Simay ^a   Piryatinsky, Irene ^b   Gavett, Rebecca A ^b   Ahmed, Omar J ^c  

^a UNIVERSITY OF RHODE ISLAND   (United States)

^b BROWN UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

DBS; Deep brain stimulation; Depression; Parkinson's disease; Randomized clinical trial

Indexed keywords

ADVERSE OUTCOME; AGGRESSION; ANXIETY; BRAIN DEPTH STIMULATION; BRAIN REGION; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DEPRESSION; GLOBUS PALLIDUS; HUMAN; INSOMNIA; IRRITABILITY; OBSESSIVE COMPULSIVE DISORDER; PARANOIA; PARKINSON DISEASE; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SCORING SYSTEM; SELF REPORT; SUBTHALAMIC NUCLEUS; SUICIDE; TREATMENT RESPONSE;

EID: 84906494005     PISSN: None     EISSN: 16642295     Source Type: Journal    
DOI: 10.3389/fneur.2014.00154     Document Type: Review

References (62)

1. Wright Willis A, Evanoff BA, Lian M, Criswell SR, Racette BA. Geographic and ethnic variation in Parkinson disease: a population-based study of US Medicare beneficiaries. Neuroepidemiology (2010) 34:143-51. doi: 10.1159/000275491
2. Hassan A, Wu SS, Schmidt P, Malaty I, Dai YF, Miyasaki JM, et al. What are the issues facing Parkinson's disease patients at ten years of disease and beyond? Data from the NPF-QII study. Parkinsonism Relat Disord (2012) 18:925-30. doi:10.1016/j.parkreldis.2012.06.014
3. Slaughter JR, Slaughter KA, Nichols D, Holmes SE, Martens MP. Prevalence, clinical manifestations, etiology, and treatment of depression in Parkinson's disease. J Neuropsychiatry Clin Neurosci (2001) 12:187-96. doi:10.1176/appi.neuropsych.13.2.187
4. Schrag A, Jahanshahi M, Quinn N. How does Parkinson's disease affect quality of life? A comparison with quality of life in the general population. Mov Disord (2001) 15:1112-8. doi:10.1002/1531-8257(200011)15:6<1112::AID-MDS1008>3.0.CO;2-A
5. Yahr MD, Brodsky MA. Parkinson's disease. In: Ramachandran VS, editor. Encyclopedia of the Human Brain. (Vol. 3), San Diego: Academic Press (2002). p. 777-86.
6. Veazey C, Aki SOE, Cook KF, Lai EC, Kunik ME. Prevalence and treatment of depression in Parkinson's disease. J Neuropsychiatry Clin Neurosci (2005) 1:310-23. doi:10.1176/appi.neuropsych.17.3.310
7. Eskow Jaunarajs KL, Angoa-Perez M, Kuhn DM, Bishop C. Potential mechanisms underlying anxiety and depression in Parkinson's disease: consequences of L-DOPA treatment. Neurosci Biobehav Rev (2011) 35:556-64. doi:10.1016/j.neubiorev.2010.06.007
8. Chwastiak L, Ehde DM, Gibbons LE, Sullivan M, Bowen JD, Kraft GH. Depressive symptoms and severity of illness in multiple sclerosis: epidemiologic study of a large community sample. Am J Psychiatry (2002) 159:1862-8. doi:10.1176/appi.ajp.159.11.1862
9. Wragg RE, Jeste DV. Overview of depression and psychosis in Alzheimer's disease. Am J Psychiatry (1989) 146:577-87.
10. Wang G, Hong Z, Cheng Q, Xiao Q, Wang Y, Zhang J, et al. Validation of the Chinese non-motor symptoms scale for Parkinson's disease: results from a Chinese pilot study. Clin Neurol Neurosurg (2009) 111:523-6. doi:10.1016/j.clineuro.2009.02.005
11. Aarsland D, Brønnick K, Alves G, Tysnes OB, Pedersen KF, Ehrt U, et al. The spectrum of neuropsychiatric symptoms in patients with early untreated Parkinson's disease. J Neurol Neurosurg Psychiatry (2009) 80:928-30. doi:10.1136/jnnp.2008.166959
12. Ziemssen T, Reichmann H. Non-motor dysfunction in Parkinson's disease. Parkinsonism Relat Disord (2007) 13:323-32. doi:10.1016/j.parkreldis.2006.12.014
13. Wood LD, Neumiller JJ, Setter SM, Dobbins EK. Clinical review of treatment of options for select nonmotor symptoms of Parkinson's disease. Am J Geriatr Pharmacother (2010) 8:294-315. doi:10.1016/j.amjopharm.2010.08.002
14. Fall P, Granérus AK. Maintenance ECT in Parkinson's disease. J Neural Transm (1999) 106:737-41. doi:10.1007/s007020050194
15. Truong DD, Bhidayasiri R, Wolters E. Management of non-motor symptoms in advanced Parkinson disease. J Neurol Sci (2008) 266:216-28. doi:10.1016/j.jns.2007.08.015
16. Okun MS. Deep brain stimulation for Parkinson's disease. N Engl J Med (2012) 367:1529-38. doi:10.1056/NEJMct1208070
17. Holtzheimer PE, Mayberg HS. Deep brain stimulation for psychiatric disorders. Annu Rev Neurosci (2011) 34:289-307. doi:10.1146/annurev-neuro-061010-113638
18. Storch A, Ebersbach G, Fuchs G, Jost WH, Odin P, Reifschneider G, et al. Depression in Parkinson's disease. Part 1: epidemiology, signs and symptoms, pathophysiology and diagnosis. Fortschr Neurol Psychiatr (2008) 76:715-24. doi:10.1055/s-2008-1038293
19. Wichmann T, Delong MR. Deep brain stimulation for neurologic and neuropsychiatric disorders. Neuron (2006) 52:197-204. doi:10.1016/j.neuron.2006.09.02218
20. Ashkan K, Samuel M, Reddy P, Chaudhuri KR. The impact of deep brain stimulation on the nonmotor symptoms of Parkinson's disease. J Neural Transm (2012) 120(4):639-42. doi:10.1007/s00702-012-0912-x
21. Campbell MC, Black KJ, Weaver PM, Lugar HM, Videen TO, Tabbal SD, et al. Mood response to deep brain stimulation of the subthalamic nucleus in Parkinson's disease. J Neuropsychiatry Clin Neurosci (2012) 24:28-36. doi:10.1176/appi.neuropsych.11030060
22. Altug F, Acar F, Acar G, Cavlak U. The influence of subthalamic nucleus deep brain stimulation on physical, emotional, cognitive functions and daily living activities in patients with Parkinson's disease. Turk Neurosurg (2011) 21(2):140-6. doi:10.5137/1019-5149.JTN.3956-10.0
23. Takeshita S, Kurisu K, Trop L, Arita K, Akimitsu T, Verhoeff NPLG. Effect of subthalamic stimulation on mood state in Parkinson's disease: evaluation of previous facts and problems. Neurosurg Rev (2005) 28:179-86. doi:10.1007/s10143-005-0387-4
24. Okun MS, Green J, Saben R, Gross R, Foote KD, Vitek JL. Mood changes with deep brain stimulation of STN and GPi: results of a pilot study. J Neurol Neurosurg Psychiatry (2003) 74:1584-6. doi:10.1136/jnnp.74.11.1584
25. DeLong MR, Whicmann T. Circuits and circuit disorders of the basal ganglia. Arch Neurol (2007) 64:20-4. doi:10.1001/archneur.64.1.20
26. Wagle Shukla A, Okun MS. Personalized medicine in deep brain stimulation through utilization of neural oscillations. Neurology (2012) 78:1900-1. doi:10.1212/WNL.0b013e318259e2af
27. Cotzias GC, Papavasiliou PS, Gellene R. Modification of Parkinsonism-chronic treatment with L-DOPA. N Engl J Med (1969) 280:337-45. doi:10.1056/NEJM196902132800701
28. Poewe WH, Lees AJ, Stern GM. Low-dose L-DOPA therapy in Parkinson's disease: a 6-year follow-up study. Neurology (1986) 36:1528-30. doi:10.1212/WNL.36.11.1528
29. Schrag A, Quinn N. Dyskinesias and motor fluctuations in Parkinson's disease: a community-based study. Brain (2000) 123:2297-305. doi:10.1093/brain/123.11.2297
30. Chase TN, Mouradian MM, Engber TM. Motor response complications and the function of striatal efferent systems. Neurology (1993) 43:S23-7.
31. Choi C, Sohn YH, Lee JH, Kim J. The effect of long-term levodopa therapy on depression level in de novo patients with Parkinson's disease. J Neurol Sci (2000) 172:12-6. doi:10.1016/S0022-510X(99)00198-7
32. Kim HJ, Park SY, Cho YJ, Hong KS, Cho JY, Seo SY, et al. Nonmotor symptoms in de novo Parkinson disease before and after dopaminergic treatment. J Neurol Sci (2009) 287:200-4. doi:10.1016/j.jns.2009.07.026
33. Negre-Pages L, Grandjean H, Lapeyre-Mestre M, Montastruc JL, Fourrier A, Lépine JP, et al. Anxious and depressive symptoms in Parkinson's disease: the French cross-sectionnal DoPaMiP study. Mov Disord (2010) 25:157-66. doi:10.1002/mds.22760
34. Marsh GG, Markham CH. Does levodopa alter depression and psychopathology in Parkinsonism patients? J Neurol Neurosurg Psychiatry (1973) 36:925-35. doi:10.1136/jnnp.36.6.925
35. Palhagen SE, Carlsson M, Curman E, Walinder J, Granérus AK. Depressive illness in Parkinson's disease - indication of a more advanced and widespread neurodegenerative process? Acta Neurol Scand (2008) 117:295-304. doi:10.1111/j.1600-0404.2007.00986.x
36. Suzuki K, Miyamoto M, Miyamoto T, Okuma Y, Hattori N, Kamei S, et al. Correlation between depressive symptoms and nocturnal disturbances in Japanese patients with Parkinson's disease. Parkinsonism Relat Disord (2008) 15:15-9. doi:10.1016/j.parkreldis.2008.02.002
37. Bergman H, Wichmann T, DeLong MR. Reversal of experimental parkinsonism by lesions of the subthalamic nucleus. Science (1990) 249:1436-8. doi:10.1126/science.2402638
38. Moro E, Hamani C, Poon YY, Al-Khairallah T, Dostrovsky JO, Hutchison WD, et al. Unilateral pedunculopontine stimulation improves falls in Parkinson's disease. Brain (2010) 133:215-24. doi:10.1093/brain/awp261
39. Schroeder U, Kuehler A, Lange KW, Haslinger B, Tronnier VM, Krause M, et al. Subthalamic nucleus stimulation affects a frontotemporal network: a PET study. Ann Neurol (2003) 54:445-50. doi:10.1002/ana.10683
40. Daniele A, Albanese A, Contarino MF, Zinzi P, Barbier A, Gasparini F, et al. Cognitive and behavioural effects of chronic stimulation of the subthalamic nucleus in patients with Parkinson's disease. J Neurol Neurosurg Psychiatry (2003) 74:175-82. doi:10.1136/jnnp.74.2.175
41. Woods SP, Fields JA, Troster AI. Neuropsychological sequelae of subthalamic nucleus deep brain stimulation in Parkinson's disease: a critical review. Neuropsychol Rev (2002) 12:111-26. doi:10.1023/A:1016806711705
42. Temel Y, Kessels A, Tan S, Topdag A, Boon P, Visser-Vandewalle V. Behavioural changes after bilateral subthalamic stimulation in advanced Parkinson disease: a systematic review. Parkinsonism Relat Disord (2006) 12:265-72. doi:10.1016/j.parkreldis.2006.01.004
43. Kaiser I, Kryspin-Exner I, Brucke T, Volc D, Alesch F. Long-term effects of STN DBS on mood: psychosocial profiles remain stable in a 3-year follow-up. BMC Neurol (2008) 8:43. doi:10.1186/1471-2377-8-43
44. Castelli L, Zibetti M, Rizzi L, Caglio M, Lanotte M, Lopiano L. Neuropsychiatric symptoms three years after subthalamic DBS in PD patients: a case-control study. J Neurol (2008) 255:1515-20. doi:10.1007/s00415-008-0955-y
45. Okun MS, Wu SS, Foote KD, Bowers D, Gogna S, Price C, et al. Do stable patients with a premorbid depression history have worse outcome after deep brain stimulation for Parkinson disease? Neurosurgery (2011) 69:357-61. doi:10.1227/NEU.0b013e3182160456
46. Follett KA, Weaver FM, Stern M, Hur K, Harris CL, Luo P, et al. Pallidal versus subthalamic deep-brain stimulation for Parkinson's disease. N Engl J Med (2010) 362:2077-91. doi:10.1056/NEJMoa0907083
47. Okun MS, Fernandez HH, Wu SS, Kirsch-Darrow L, Bowers D, Bova F, et al. Cognition and mood in Parkinson's disease in subthalamic nucleus versus globus pallidus interna deep brain stimulation: the COMPARE trial. Ann Neurol (2009) 65:586-95. doi:10.1002/ana.21596
48. Weaver FM, Follett K, Stern M, Hur K, Harris C, Marks WJ Jr, et al. Bilateral deep brain stimulation vs best medical therapy for patients with advanced Parkinson disease: a randomized controlled trial. JAMA (2009) 301:63-73. doi:10.1001/jama.2008.929
49. Zahodne LB, Okun MS, Foote KD, Fernandez HH, Rodriguez RL, Wu SS. Greater improvement in quality of life following unilateral deep brain stimulation surgery in the globus pallidus as compared to the subthalamic nucleus. J Neurol (2009) 256:1321-9. doi:10.1007/s00415-009-5121
50. Merello M, Tenca E, Llloret SP, Martin ME, Bruno SC, Antico J, et al. Prospective randomized 1-year follow-up comparison of bilateral subthalamotomy versus bilateral subthalamic stimulation and the combination of both in Parkinsons' disease patients: a pilot study. Br J Neurosurg (2008) 22:415-22. doi:10.1080/02688690801971667
51. Witt K, Daniels C, Reiff J, Krack P, Volkmann J, Pinsker MO, et al. Neuropsychological and psychiatric changes after deep brain stimulation for Parkinson's disease: a randomised, multicentre study. Lancet Neurol (2008) 7:605-14. doi:10.1016/S1474-4422(08)70114-5
52. Dujardin K, Krystkowiak P, Defebvre L, Blond S, Destée A. A case of severe dysexecutive syndrome consecutive to chronic bilateral pallidal stimulation. Neuropsychologia (2000) 38:1305-15. doi:10.1016/S0028-3932(00)00027-0
53. Volkmann J, Sturm V, Weiss P, Kappler J, Voges J, Koulousakis A, et al. Bilateral high-frequency stimulation of the internal globus pallidus in advanced Parkinson's disease. Ann Neurol (1998) 44:953-61. doi:10.1002/ana.410440615
54. Tröster AI, Fields JA, Wilkinson SB, Pahwa R, Miyawaki E, Lyons KE, et al. Unilateral pallidal stimulation for Parkinson's disease: neurobehavioral functioning before and 3 months after electrode implantation. Neurology (1998) 49:1078-83. doi:10.1212/WNL.49.4.1078
55. Voon V, Krack P, Lang AE, Lozano AM, Dujardin K, Schüpbach M, et al. A multicentre study on suicide outcomes following subthalamic stimulation for Parkinson's disease. Brain (2008) 131:2720-8. doi:10.1093/brain/awn214
56. Houeto JL, Mesnage V, Mallet L, Pillon B, Garguilo M, du Moncel ST, et al. Behavioural disorders, Parkinson's disease, and subthalamic stimulation. J Neurol Neurosurg Psychiatry (2002) 72:701-7. doi:10.1136/jnnp.72.6.701
57. Saint-Cyr JA, Trepanier LL, Kumar R, Lozano AM, Lang AE. Neuropsychological consequences of chronic bilateral stimulation of the subthalamic nucleus in Parkinson's disease. Brain (2000) 123:2091-108. doi:10.1093/brain/123.10.2091
58. Stefurak T, Mikulis D, Mayberg H, Lang AE, Hevenor S, Pahapill P, et al. Deep brain stimulation for Parkinson's disease dissociates mood and motor circuits: a functional MRI case study. Mov Disord (2003) 18:1508-16. doi:10.1002/mds.10593
59. Perozzo P, Rizzone M, Bergamasco B, Castelli L, Lanotte M, Tavella A, et al. Deep brain stimulation of subthalamic nucleus: behavioral modifications and familiar relations. Neurol Sci (2001) 22:81-2. doi:10.1007/s100720170057
60. Agid Y, Arnulf I, Bejjani P, Bloch F, Bonnet AM, Damier P, et al. Parkinson's disease is a neuropsychiatric disorder. Adv Neurol (2003) 91:365-70.
61. Middleton FA, Strick PL. Basal ganglia output and cognition: evidence from anatomical, behavioral, and clinical studies. Brain Cogn (2000) 42:183-200. doi:10.1006/brcg.1999.1099
62. Gradinaru V, Mogri M, Thompson KR, Henderson JM, Deisseroth K. Optical deconstruction of parkinsonian neural circuitry. Science (2009) 324:354-9. doi:10.1126/science.1167093