Clearing lactate is clearly better...But how much?

Critical Care Medicine

Volumn 42, Issue 9, 2014, Pages 2149-2150

  Puskarich, Michael A ^a   Jones, Alan E ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

lactate; mortality; sepsis

Indexed keywords

LACTIC ACID;

CLEARANCE; CONSENSUS; CRITICAL ILLNESS; CRITICALLY ILL PATIENT; EDITORIAL; EMERGENCY WARD; HUMAN; INTENSIVE CARE UNIT; LACTATE CLEARANCE; MORTALITY; PERFUSION; PRACTICE GUIDELINE; PRIORITY JOURNAL; PROGNOSIS; RESUSCITATION; RISK FACTOR; RISK REDUCTION; SEPSIS; SEPTIC SHOCK; SURVIVAL; SURVIVOR;

CRITICAL ILLNESS; LACTIC ACID;

EID: 84906351305     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0000000000000455     Document Type: Editorial

References (4)

1. Zhang Z, Xu X: Lactate Clearance Is a Useful Biomarker for the Prediction of All-Cause Mortality in Critically Ill Patients: A Systematic Review and Meta-Analysis. Crit Care Med 2014; 42:2118-2125
2. Jansen TC, van Bommel J, Schoonderbeek FJ, et al; LACTATE study group: Early lactate-guided therapy in intensive care unit patients: A multicenter, open-label, randomized controlled trial. Am J Resp Crit Care Med 2010; 182:752-761
3. Puskarich MA, Trzeciak S, Shapiro NI, et al: Whole blood lactate kinetics in patients undergoing quantitative resuscitation for severe sepsis and septic shock. Chest 2013; 143:1548-1553
4. Jones AE, Shapiro NI, Trzeciak S, et al; Emergency Medicine Shock Research Network (EMShockNet) Investigators: Lactate clearance vs central venous oxygen saturation as goals of early sepsis therapy: A randomized clinical trial. JAMA 2010; 303:739-746