Endocannabinoid 2-arachidonylglycerol protects primary cultured neurons against LPS-induced impairments in rat caudate nucleus

Journal of Molecular Neuroscience

Volumn 54, Issue 1, 2014, Pages 49-58

  Lu, Yongli ^a   Peng, Fang ^a   Dong, Manman ^a   Yang, Hongwei ^a  

^a CHINA THREE GORGES UNIVERSITY   (China)

Author keywords

2 Arachidonoylglycerol (2 AG); Cannabinoid receptor; Caudate nucleus (CN); Endocannabinoid; Lipopolysaccharide (LPS); Sodium channel

Indexed keywords

2 ARACHIDONOYLGLYCEROL; CANNABINOID 1 RECEPTOR; CYCLOOXYGENASE 2; ENDOCANNABINOID; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; VOLTAGE GATED SODIUM CHANNEL; 2-ARACHIDONYLGLYCEROL; ACYLGLYCEROL; ARACHIDONIC ACID DERIVATIVE; CANNABINOID RECEPTOR AGONIST; NEUROPROTECTIVE AGENT; SODIUM CHANNEL;

ANIMAL CELL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CAUDATE NUCLEUS; CONTROLLED STUDY; DEGENERATIVE DISEASE; HYPERPOLARIZATION; INFLAMMATION; NERVE CELL CULTURE; NEUROLOGIC DISEASE; NEUROPROTECTION; NONHUMAN; PROTEIN EXPRESSION; RAT; ACTION POTENTIAL; ANIMAL; CELL CULTURE; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; NERVE CELL; PHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

RATTUS;

ACTION POTENTIALS; ANIMALS; ARACHIDONIC ACIDS; CANNABINOID RECEPTOR AGONISTS; CAUDATE NUCLEUS; CELLS, CULTURED; CYCLOOXYGENASE 2; ENDOCANNABINOIDS; GLYCERIDES; LIPOPOLYSACCHARIDES; MAP KINASE SIGNALING SYSTEM; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNELS;

EID: 84906342920     PISSN: 08958696     EISSN: 15591166     Source Type: Journal    
DOI: 10.1007/s12031-014-0246-2     Document Type: Article

References (40)

1. Amir R, Argoff CE, Bennett GJ, Cummins TR, Durieux ME, Gerner P et al (2006) The role of sodium channels in chronic inflammatory and neuropathic pain. J Pain 7:S1-S29
2. Aoki T, Narumiya S (2012) Prostaglandins and chronic inflammation. Trends Pharmacol Sci 33:304-311
3. Araldi D, Ferrari LF, Lotufo CM, Vieira AS, Athié MC, Figueiredo JG et al (2013) Peripheral inflammatory hyperalgesia depends on the COX increase in the dorsal root ganglion. Proc Natl Acad Sci U S A 110:3603-3608
4. Barnéoud P, Mazadier M, Miquet JM, Parmentier S, Dubédat P, Doble A et al (1996) Neuroprotective effects of riluzole on a model of Parkinson's disease in the rat. Neuroscience 74:971-983 (Pubitemid 26313341)
5. Black JA, Liu S, Tanaka M, Cummins TR, Waxman SG (2004) Changes in the expression of tetrodotoxin-sensitive sodium channels within dorsal root ganglia neurons in inflammatory pain. Pain 108:237-247 (Pubitemid 38353046)
6. Brück A, Portin R, Lindell A, Laihinen A, Bergman J, Haaparanta M et al (2001) Positron emission tomography shows that impaired frontal lobe functioning in Parkinson 's disease is related to dopaminergic hypofunction in the caudate nucleus. Neurosci Lett 311:81-84 (Pubitemid 32900610)
7. Chang YH, Lee ST, Lin WW (2001) Effects of cannabinoids on LPSstimulated inflammatory mediator release from macrophages: involvement of eicosanoids. J Cell Biochem 81:715-723 (Pubitemid 32417096)
8. Chen X, Zhang J, Chen C (2011) Endocannabinoid 2-arachidonoylglycerol protects neurons against β-amyloid insults. Neuroscience 178:159-168
9. Docherty RJ, Farmer CE (2009) The pharmacology of voltage-gated sodium channels in sensory neurones. Handb Exp Pharmacol 194: 519-561
10. Duan Y, Zheng J, Nicholson RA (2008) Inhibition of [3H]batrachotoxinin A-20alpha-benzoate binding to sodium channels and sodium channel function by endocannabinoids. Neurochem Int 52: 438-446
11. Eljaschewitsch E, Witting A, Mawrin C, Lee T, Schmidt PM, Wolf S et al (2006) The endocannabinoid anandamide protects neurons during CNS inflammation by induction of MKP-1 in microglial cells. Neuron 49:67-79 (Pubitemid 43017186)
12. England S, Bevan S, Docherty RJ (1996) PGE2 modulates the tetrodotoxin-resistant sodium current in neonatal rat dorsal root ganglion neurones via the cyclic AMP-protein kinase A cascade. J Physiol 495:429-440 (Pubitemid 26331824)
13. Freund TF, Katona I, Piomelli D (2003) Role of endogenous cannabinoids in synaptic signaling. Physiol Rev 83:1017-1066 (Pubitemid 36828930)
14. Gold MS, Reichling DB, Shuster MJ, Levine JD (1996) Hyperalgesic agents increase a tetrodotoxin-resistant Na+ current in nociceptors. Proc Natl Acad Sci U S A 93:1108-1112 (Pubitemid 26052849)
15. Hillard CJ (2000) Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. Prostaglandins Other Lipid Mediat 61:3-18
16. Jain NK, Patil CS, Kulkarni SK, Singh A (2002) Modulatory role of cyclooxygenase inhibitors in aging- and scopolamine or lipopolysaccharide- induced cognitive dysfunction in mice. Behav Brain Res 133:369-376 (Pubitemid 34754412)
17. Jung GY, Lee JY, Rhim H, Oh TH, Yune TY (2013) An increase in voltage-gated sodium channel current elicits microglial activation followed inflammatory responses in vitro and in vivo after spinal cord injury. Glia 61:1807-1821
18. Ke Y, Song WW, Dong MM, Peng F, Yang HW (2013) Cyclooxgense-2 mediated antagonised effect of curcumin on LPS induced impairment of neurons in caudate nucleus. Lishizhen Med Mater Med Res 24:2590-2592
19. Korotzer AR, Cotman CW (1992) Voltage-gated currents expressed by rat microglia in culture. Glia 6:81-88
20. Kotz SA, Anwander A, Axer H, Knösche TR (2013) Beyond cytoarchitectonics: the internal and external connectivity structure of the caudate nucleus. PLoS One 8:e70141
21. Luchicchi A, Pistis M (2012) Anandamide and 2-arachidonoylglycerol: pharmacological properties, functional features, and emerging specificities of the twomajor endocannabinoids.Mol Neurobiol 46:374-392
22. Lynch AM, Walsh C, Delaney A, Nolan Y, Campbell VA, Lynch MA (2004) Lipopolysaccharide-induced increase in signalling in hippocampus is abrogated by IL-10-a role for IL-1 beta? J Neurochem 88:635-646 (Pubitemid 38140208)
23. Mechoulam R, Ben-Shabat S, Hanus L, Ligumsky M, Kaminski NE, Schatz AR et al (1995) Identification of an endogenous 2-monoglyceride, present in canine gut that binds to cannabinoid receptors. Biochem Pharmacol 50:83-90
24. Okada Y, Imendra KG, Miyazaki T, Hotokezaka H, Fujiyama R, Zeredo JL et al (2005) Biophysical properties of voltage-gated Na+ channels in frog parathyroid cells and their modulation by cannabinoids. J Exp Biol 208:4747-4756 (Pubitemid 43120020)
25. Oz M (2006) Receptor-independent actions of cannabinoids on cell membranes: focus on endocannabinoids. Pharmacol Ther 111: 114-144
26. Panikashvili D, Simeonidou C, Ben-Shabat S, Hanus L, Breuer A, Mechoulam R et al (2001) An endogenous cannabinoid (2-AG) is neuroprotective after brain injury. Nature 413:527-531 (Pubitemid 32938751)
27. Panikashvili D, Shein NA, Mechoulam R, Trembovler V, Kohen R, Alexandrovich A et al (2006) The endocannabinoid 2-AG protects the blood-brain barrier after closed head injury and inhibits mRNA expression of proinflammatory cytokines. Neurobiol Dis 22:257-264
28. Peng F, LU YL, Yang HW (2012) Primary culture of neurons from caudate nucleus and study on the characteristics of ion channels. J Chin Med Univ 41:676-678
29. Pertwee RG(2005) Pharmacological actions of cannabinoids. Handb Exp Pharmacol 168:1-51
30. Pertwee RG (2010) Receptors and channels targeted by synthetic cannabinoid receptor agonists and antagonists. Curr Med Chem 17:1360-1381
31. Sprengelmeyer R, Canavan AG, Lange HW, Hömberg V (1995) Associative learning in degenerative neostriatal disorders: contrasts in explicit and implicit remembering between Parkinson's and Huntington's diseases. Mov Disord 10:51-65
32. Sugiura T, Waku K (2002) Cannabinoid receptors and their endogenous ligands. J Biochem 132:7-12 (Pubitemid 34832264)
33. Sugiura T, Kishimoto S, Oka S, Gokoh M (2006) Biochemistry, pharmacology and physiology of 2-arachidonoylglycerol, an endogenous cannabinoid receptor ligand. Prog Lipid Res 45:405-446
34. Tanaka M, Cummins TR, Ishikawa K, Dib-Hajj SD, Black JA, Waxman SG (1998) SNS Na+ channel expression increases in dorsal root ganglion neurons in the carrageenan inflammatory pain model. Neuroreport 9:967-972 (Pubitemid 28266606)
35. Walter L, Stella N (2004) Cannabinoids and neuroinflammation. Br J Pharmacol 14:775-785 (Pubitemid 38446178)
36. Waxman SG, Cummins TR, Dib-Hajj S, Fjell J, Black JA (1999) Sodium channels, excitability of primary sensory neurons, and themolecular basis of pain. Muscle Nerve 22:1177-1187 (Pubitemid 29409685)
37. Williams AJ, Tortella FC (2002) Neuroprotective effects of the sodium channel blocker RS100642 and attenuation of ischemia-induced brain seizures in the rat. Brain Res 932:45-55 (Pubitemid 34241593)
38. Yang H, Chen C (2008) Cyclooxygenase-2 in synaptic signaling. Curr Pharm Des 14:1443-1451 (Pubitemid 351993045)
39. Zhang J, Chen C (2008) Endocannabinoid 2-arachidonoylglycerol protects neurons by limiting COX-2 elevation. J Biol Chem 283: 22601-22611
40. Zogopoulos P, Vasileiou I, Patsouris E, Theocharis S (2013) The neuroprotective role of 1endocannabinoids against chemicalinduced injury and other adverse effects. J Appl Toxicol 33: 246-264