-
1
-
-
81555216077
-
Gene expression profiling in breast cancer: Classification, prognostication, and prediction
-
Reis-Filho JS, Pusztai L. Gene expression profiling in breast cancer: classification, prognostication, and prediction. Lancet 2011;378(9805):1812-23
-
(2011)
Lancet
, vol.378
, Issue.9805
, pp. 1812-1823
-
-
Reis-Filho, J.S.1
Pusztai, L.2
-
2
-
-
0035845511
-
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
-
Sørlie T, Perou CM, Tibshirani R, et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 2001;98(19):10869-74
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.19
, pp. 10869-10874
-
-
Sørlie, T.1
Perou, C.M.2
Tibshirani, R.3
-
3
-
-
0037478605
-
Repeated observation of breast tumor subtypes in independent gene expression data sets
-
Sørlie T, Tibshirani R, Parker J, et al. Repeated observation of breast tumor subtypes in independent gene expression data sets. Proc Natl Acad Sci USA 2003;100(14):8418-23
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.14
, pp. 8418-8423
-
-
Sørlie, T.1
Tibshirani, R.2
Parker, J.3
-
4
-
-
30944450821
-
Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma
-
Livasy CA, Karaca G, Nanda R, et al. Phenotypic evaluation of the basal-like subtype of invasive breast carcinoma. Mod Pathol 2005;19(2):264-71
-
(2005)
Mod Pathol
, vol.19
, Issue.2
, pp. 264-271
-
-
Livasy, C.A.1
Karaca, G.2
Nanda, R.3
-
5
-
-
22244449596
-
High-throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses
-
Abd El-Rehim DM, Ball G, Pinder SE, et al. High-throughput protein expression analysis using tissue microarray technology of a large well-characterised series identifies biologically distinct classes of breast cancer confirming recent cDNA expression analyses. Int J Cancer 2005;116(3):340-50
-
(2005)
Int J Cancer
, vol.116
, Issue.3
, pp. 340-350
-
-
Abd El-Rehim, D.M.1
Ball, G.2
Pinder, S.E.3
-
6
-
-
4143150688
-
Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma
-
Nielsen TO, Hsu FD, Jensen K, et al. Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma. Clin Cancer Res 2004;10(16):5367-74
-
(2004)
Clin Cancer Res
, vol.10
, Issue.16
, pp. 5367-5374
-
-
Nielsen, T.O.1
Hsu, F.D.2
Jensen, K.3
-
7
-
-
0036849017
-
Cytogenetic alterations and cytokeratin expression patterns in breast cancer: Integrating a new model of breast differentiation into cytogenetic pathways of breast carcinogenesis
-
Korsching E, Packeisen J, Agelopoulos K, et al. Cytogenetic alterations and cytokeratin expression patterns in breast cancer: integrating a new model of breast differentiation into cytogenetic pathways of breast carcinogenesis. Lab Invest 2002;82(11):1525-33
-
(2002)
Lab Invest
, vol.82
, Issue.11
, pp. 1525-1533
-
-
Korsching, E.1
Packeisen, J.2
Agelopoulos, K.3
-
8
-
-
33745590399
-
The challenging estrogen receptor-negative/progesterone receptor-Negative/HER-2-negative patient: A promising candidate for epidermal growth factor receptor-targeted therapy?
-
Siziopikou KP, Ariga R, Proussaloglou KE, et al. The challenging estrogen receptor-negative/progesterone receptor-Negative/HER-2-negative patient: a promising candidate for epidermal growth factor receptor-targeted therapy? Breast J 2006;12(4):360-2
-
(2006)
Breast J
, vol.12
, Issue.4
, pp. 360-362
-
-
Siziopikou, K.P.1
Ariga, R.2
Proussaloglou, K.E.3
-
9
-
-
84885735554
-
Mutational landscape and significance across 12 major cancer types
-
Kandoth C, McLellan MD, Vandin F, et al. Mutational landscape and significance across 12 major cancer types. Nature 2013;502(7471):333-9
-
(2013)
Nature
, vol.502
, Issue.7471
, pp. 333-339
-
-
Kandoth, C.1
McLellan, M.D.2
Vandin, F.3
-
11
-
-
79960015997
-
Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies
-
Lehmann BD, Bauer JA, Chen X, et al. Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies. J Clin Invest 2011;121(7):2750-67
-
(2011)
J Clin Invest
, vol.121
, Issue.7
, pp. 2750-2767
-
-
Lehmann, B.D.1
Bauer, J.A.2
Chen, X.3
-
12
-
-
79959524883
-
Directed therapy of subtypes of triple-negative breast cancer
-
Suppl 1
-
Carey LA. Directed therapy of subtypes of triple-negative breast cancer. Oncologist 2011;16(Suppl 1):71-8
-
(2011)
Oncologist
, vol.16
, pp. 71-78
-
-
Carey, L.A.1
-
13
-
-
84867072867
-
Targeted therapy for triple-negative breast cancer: Where are we?
-
Duffy MJ, McGowan PM, Crown J. Targeted therapy for triple-negative breast cancer: where are we? Int J Cancer 2012;131(11):2471-7
-
(2012)
Int J Cancer
, vol.131
, Issue.11
, pp. 2471-2477
-
-
Duffy, M.J.1
McGowan, P.M.2
Crown, J.3
-
14
-
-
69149089019
-
Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer
-
Graveel CR, DeGroot JD, Su Y, et al. Met induces diverse mammary carcinomas in mice and is associated with human basal breast cancer. Proc Natl Acad Sci USA 2009;106(31):12909-14
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.31
, pp. 12909-12914
-
-
Graveel, C.R.1
Degroot, J.D.2
Su, Y.3
-
15
-
-
84866594844
-
Targeting the hepatocyte growth Factor - CMET axis in cancer therapy
-
Blumenschein GR, Mills GB, Gonzalez-Angulo AM. Targeting the hepatocyte growth Factor - cMET axis in cancer therapy. J Clin Oncol 2012;30(26):3287-96
-
(2012)
J Clin Oncol
, vol.30
, Issue.26
, pp. 3287-3296
-
-
Blumenschein, G.R.1
Mills, G.B.2
Gonzalez-Angulo, A.M.3
-
16
-
-
84879761446
-
MET: A critical player in tumorigenesis and therapeutic target
-
doi:10. 1101/cshperspect. a009209
-
Graveel CR, Tolbert D, Vande Woude GF. MET: A critical player in. tumorigenesis and therapeutic target. Cold Spring Harb Perspect Biol 2013;5(7): doi:10. 1101/cshperspect. a009209
-
(2013)
Cold Spring Harb Perspect Biol
, vol.5
, Issue.7
-
-
Graveel, C.R.1
Tolbert, D.2
Vande Woude, G.F.3
-
17
-
-
0021241398
-
Molecular cloning of a new transforming gene from a chemically transformed human cell line
-
Cooper CS, Park M, Blair DG, et al. Molecular cloning of a new transforming gene from a chemically transformed human cell line. Nature 1984;311(5981):29-33
-
(1984)
Nature
, vol.311
, Issue.5981
, pp. 29-33
-
-
Cooper, C.S.1
Park, M.2
Blair, D.G.3
-
18
-
-
1242348060
-
Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors
-
Park M, Dean M, Kaul K, et al. Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. Proc Natl Acad Sci USA 1987;84(18):6379-83
-
(1987)
Proc Natl Acad Sci USA
, vol.84
, Issue.18
, pp. 6379-6383
-
-
Park, M.1
Dean, M.2
Kaul, K.3
-
19
-
-
0036006814
-
Role of the hepatocyte growth factor receptor, c-met, in oncogenesis and potential for therapeutic inhibition
-
Gautam M, Shrikhande A, Kijima T, et al. Role of the hepatocyte growth factor receptor, c-met, in oncogenesis and potential for therapeutic inhibition. Cytokine Growth Factor Rev 2002;13(1):41-59
-
(2002)
Cytokine Growth Factor Rev
, vol.13
, Issue.1
, pp. 41-59
-
-
Gautam, M.1
Shrikhande, A.2
Kijima, T.3
-
20
-
-
0023790119
-
Structure of the met protein and variation of the met protein kinase activity among human tumour cell lines
-
Tempest PR, Stratton MR, Cooper CS. Structure of the met protein and variation of the met protein kinase activity among human tumour cell lines. Br J Cancer 1988;58(1):3-7
-
(1988)
Br J Cancer
, vol.58
, Issue.1
, pp. 3-7
-
-
Tempest, P.R.1
Stratton, M.R.2
Cooper, C.S.3
-
21
-
-
0023668638
-
Purification and subunit structure of hepatocyte growth factor from rat platelets
-
Nakamura T, Nawa K, Ichihara A, et al. Purification and subunit structure of hepatocyte growth factor from rat platelets. FEBS Lett 1987;224(2):311-16
-
(1987)
FEBS Lett
, vol.224
, Issue.2
, pp. 311-316
-
-
Nakamura, T.1
Nawa, K.2
Ichihara, A.3
-
22
-
-
77955810458
-
Structural basis for agonism and antagonism of hepatocyte growth factor
-
Tolbert WD, Daugherty-Holtrop J, Gherardi E, et al. Structural basis for agonism and antagonism of hepatocyte growth factor. Proc Natl Acad Sci USA 2010;107(30):13264-9
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.30
, pp. 13264-13269
-
-
Tolbert, W.D.1
Daugherty-Holtrop, J.2
Gherardi, E.3
-
23
-
-
0025959661
-
The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation
-
Naldini L, Vigna E, Ferracini R, et al. The tyrosine kinase encoded by the MET proto-oncogene is activated by autophosphorylation. Mol Cell Biol 1991;11(4):1793-803
-
(1991)
Mol Cell Biol
, vol.11
, Issue.4
, pp. 1793-1803
-
-
Naldini, L.1
Vigna, E.2
Ferracini, R.3
-
24
-
-
77950552463
-
Targeting the HGF/Met signalling pathway in cancer
-
Cecchi F, Rabe DC, Bottaro DP. Targeting the HGF/Met signalling pathway in cancer. Eur J Cancer 2010;46(7):1260-70
-
(2010)
Eur J Cancer
, vol.46
, Issue.7
, pp. 1260-1270
-
-
Cecchi, F.1
Rabe, D.C.2
Bottaro, D.P.3
-
25
-
-
17344381429
-
Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas
-
Schmidt L, Duh F, Chen F, et al. Germline and somatic mutations in the tyrosine kinase domain of the MET proto-oncogene in papillary renal carcinomas. Nat Genet 1997;16(1):68-73
-
(1997)
Nat Genet
, vol.16
, Issue.1
, pp. 68-73
-
-
Schmidt, L.1
Duh, F.2
Chen, F.3
-
26
-
-
0345722740
-
Somatic mutations in the kinase domain of the Met/Hepatocyte growth factor receptor gene in childhood hepatocellular carcinomas
-
Park WS, Dong SM, Kim SY, et al. Somatic mutations in the kinase domain of the Met/Hepatocyte growth factor receptor gene in childhood hepatocellular carcinomas. Cancer Res 1999;59(2):307-10
-
(1999)
Cancer Res
, vol.59
, Issue.2
, pp. 307-310
-
-
Park, W.S.1
Dong, S.M.2
Kim, S.Y.3
-
27
-
-
0034641890
-
A novel germline juxtamembrane met mutation in human gastric cancer
-
Lee J, Han S, Cho H, et al. A novel germline juxtamembrane met mutation in human gastric cancer. Oncogene 2002;19(43):4947-53
-
(2002)
Oncogene
, vol.19
, Issue.43
, pp. 4947-4953
-
-
Lee, J.1
Han, S.2
Cho, H.3
-
28
-
-
0033575864
-
Mutant met-mediated transformation is ligand-dependent and can be inhibited by HGF antagonists
-
Michieli P, Basilico C, Pennacchietti S, et al. Mutant met-mediated transformation is ligand-dependent and can be inhibited by HGF antagonists. Oncogene 1999;18(37):5221-31
-
(1999)
Oncogene
, vol.18
, Issue.37
, pp. 5221-5231
-
-
Michieli, P.1
Basilico, C.2
Pennacchietti, S.3
-
29
-
-
84890283023
-
Developing biomarkers to predict benefit from HGF/MET pathway inhibitors
-
Koeppen H, Rost S, Yauch RL. Developing biomarkers to predict benefit from HGF/MET pathway inhibitors. J Pathol 2014;232(2):210-18
-
(2014)
J Pathol
, vol.232
, Issue.2
, pp. 210-218
-
-
Koeppen, H.1
Rost, S.2
Yauch, R.L.3
-
30
-
-
77952519096
-
Clinical implications of MET gene copy number in lung cancer
-
Toschi L, Cappuzzo F. Clinical implications of MET gene copy number in lung cancer. Future Oncol 2010;6(2):239-47
-
(2010)
Future Oncol
, vol.6
, Issue.2
, pp. 239-247
-
-
Toschi, L.1
Cappuzzo, F.2
-
31
-
-
34249075147
-
MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signalling
-
Engelman JA, Zejnullahu K, Mitsudomi T, et al. MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signalling. Science 2007;316(5827):1039-43
-
(2007)
Science
, vol.316
, Issue.5827
, pp. 1039-1043
-
-
Engelman, J.A.1
Zejnullahu, K.2
Mitsudomi, T.3
-
32
-
-
0030054076
-
Coexpression of hepatocyte growth factor and receptor (met) in human breast carcinoma
-
Tuck AB, Park M, Sterns EE, et al. Coexpression of hepatocyte growth factor and receptor (met) in human breast carcinoma. Am J Pathol 1996;148(1):225-32
-
(1996)
Am J Pathol
, vol.148
, Issue.1
, pp. 225-232
-
-
Tuck, A.B.1
Park, M.2
Sterns, E.E.3
-
33
-
-
34250804017
-
Differential expression of c-met, its ligand HGF/SF and HER2/neu in DCIS and adjacent normal breast tissue
-
Lindemann K, Resau J, Nährig J, et al. Differential expression of c-met, its ligand HGF/SF and HER2/neu in DCIS and adjacent normal breast tissue. Histopathology 2007;51(1):54-62
-
(2007)
Histopathology
, vol.51
, Issue.1
, pp. 54-62
-
-
Lindemann, K.1
Resau, J.2
Nährig, J.3
-
34
-
-
84859873169
-
CMET and phospho-cMET protein levels in breast cancers and survival outcomes
-
Raghav KP, Wang W, Liu S, et al. cMET and phospho-cMET protein levels in breast cancers and survival outcomes. Clin Cancer Res 2012;18(8):2269-77
-
(2012)
Clin Cancer Res
, vol.18
, Issue.8
, pp. 2269-2277
-
-
Raghav, K.P.1
Wang, W.2
Liu, S.3
-
35
-
-
68349115160
-
FISH and immunohistochemical status of the hepatocyte growth factor receptor (c-met) in 184 invasive breast tumors
-
Carracedo A, Egervari K, Salido M, et al. FISH and immunohistochemical status of the hepatocyte growth factor receptor (c-met) in 184 invasive breast tumors. Breast Cancer Res 2009;11(2):R402
-
(2009)
Breast Cancer Res
, vol.11
, Issue.2
-
-
Carracedo, A.1
Egervari, K.2
Salido, M.3
-
36
-
-
0030791855
-
Expression of the C-Met/HGF receptor in human breast carcinoma: Correlation with tumor progression
-
Beviglia L, Matsumoto K, Lin C, et al. Expression of the C-Met/HGF receptor in human breast carcinoma: correlation with tumor progression. Int J Cancer 1997;74(3):301-9
-
(1997)
Int J Cancer
, vol.74
, Issue.3
, pp. 301-309
-
-
Beviglia, L.1
Matsumoto, K.2
Lin, C.3
-
37
-
-
0035054344
-
Expression of the hepatocyte growth factor/c-met pathway is increased at the cancer front in breast carcinoma
-
Edakuni G, Sasatomi E, Satoh T, et al. Expression of the hepatocyte growth factor/c-met pathway is increased at the cancer front in breast carcinoma. Pathol Int 2001;51(3):172-8
-
(2001)
Pathol Int
, vol.51
, Issue.3
, pp. 172-178
-
-
Edakuni, G.1
Sasatomi, E.2
Satoh, T.3
-
38
-
-
34248191183
-
Poor prognosis in breast carcinomas correlates with increased expression of targetable CD146 and c-Met and with proteomic basal-like phenotype
-
Garcia S, Dales JP, Charafe-Jauffret E, et al. Poor prognosis in breast carcinomas correlates with increased expression of targetable CD146 and c-Met and with proteomic basal-like phenotype. Hum Pathol 2007;38(6):830-41
-
(2007)
Hum Pathol
, vol.38
, Issue.6
, pp. 830-841
-
-
Garcia, S.1
Dales, J.P.2
Charafe-Jauffret, E.3
-
39
-
-
34548568953
-
Overexpression of c-met and of the transducers PI3K, FAK, JAK in breast carcinomas correlates with shorter survival and neoangiogenesis
-
Garcia S, Dales JP, Charafe-Jauffret E, et al. Overexpression of c-met and of the transducers PI3K, FAK, JAK in breast carcinomas correlates with shorter survival and neoangiogenesis. Int J Oncol 2007;31(1):48-58
-
(2007)
Int J Oncol
, vol.31
, Issue.1
, pp. 48-58
-
-
Garcia, S.1
Dales, J.P.2
Charafe-Jauffret, E.3
-
40
-
-
19944399371
-
C-met overexpression in node-positive breast cancer identifies patients with poor clinical outcome independent of Her2/ neu
-
Lengyel E, Prechtel D, Resau JH, et al. C-met overexpression in node-positive breast cancer identifies patients with poor clinical outcome independent of Her2/ neu. Int J Oncol 2005;113(4):678-82
-
(2005)
Int J Oncol
, vol.113
, Issue.4
, pp. 678-682
-
-
Lengyel, E.1
Prechtel, D.2
Resau, J.H.3
-
41
-
-
0037374303
-
Tissue microarray analysis of hepatocyte growth Factor/Met pathway components reveals a role for met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer
-
Kang JY, Dolled-Filhart M, Ocal IT, et al. Tissue microarray analysis of hepatocyte growth Factor/Met pathway components reveals a role for met, matriptase, and hepatocyte growth factor activator inhibitor 1 in the progression of node-negative breast cancer. Cancer Res 2003;63(5):1101-5
-
(2003)
Cancer Res
, vol.63
, Issue.5
, pp. 1101-1105
-
-
Kang, J.Y.1
Dolled-Filhart, M.2
Ocal, I.T.3
-
42
-
-
84891845042
-
C-met in invasive breast cancer
-
Ho-Yen CM, Green AR, Rakha EA, et al. C-met in invasive breast cancer. Cancer 2014;120(2):163-71
-
(2014)
Cancer
, vol.120
, Issue.2
, pp. 163-171
-
-
Ho-Yen, C.M.1
Green, A.R.2
Rakha, E.A.3
-
43
-
-
84895928257
-
MET is a potential target for use in combination therapy with EGFR inhibition in triplenegative/ basal-like breast cancer
-
Kim YJ, Choi J, Seo J, et al. MET is a potential target for use in combination therapy with EGFR inhibition in triplenegative/ basal-like breast cancer. Int J Cancer 2014;134(10):2424-36
-
(2014)
Int J Cancer
, vol.134
, Issue.10
, pp. 2424-2436
-
-
Kim, Y.J.1
Choi, J.2
Seo, J.3
-
44
-
-
0025210534
-
Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues
-
Tashiro K, Hagiya M, Nishizawa T, et al. Deduced primary structure of rat hepatocyte growth factor and expression of the mRNA in rat tissues. Proc Natl Acad Sci USA 1990;87(8):3200-4
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, Issue.8
, pp. 3200-3204
-
-
Tashiro, K.1
Hagiya, M.2
Nishizawa, T.3
-
45
-
-
0029948303
-
Scatter factor protein levels in human breast cancers
-
Yao Y, Jin L, Fuchs A, et al. Scatter factor protein levels in human breast cancers. Am J Pathol 1996;149(5):1707-17
-
(1996)
Am J Pathol
, vol.149
, Issue.5
, pp. 1707-1717
-
-
Yao, Y.1
Jin, L.2
Fuchs, A.3
-
46
-
-
0028353491
-
Immunoreactive hepatocyte growth factor is a strong and independent predictor of recurrence and survival in human breast cancer
-
Yamashita J, Ogawa M, Yamashita S, et al. Immunoreactive hepatocyte growth factor is a strong and independent predictor of recurrence and survival in human breast cancer. Cancer Res 1994;54(7):1630-3
-
(1994)
Cancer Res
, vol.54
, Issue.7
, pp. 1630-1633
-
-
Yamashita, J.1
Ogawa, M.2
Yamashita, S.3
-
47
-
-
69149108735
-
Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer
-
Ponzo MG, Lesurf R, Petkiewicz S, et al. Met induces mammary tumors with diverse histologies and is associated with poor outcome and human basal breast cancer. Proc Natl Acad Sci USA 2009;106(31):12903-8
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.31
, pp. 12903-12908
-
-
Ponzo, M.G.1
Lesurf, R.2
Petkiewicz, S.3
-
48
-
-
84875837439
-
Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer
-
Knight JF, Lesurf R, Zhao H, et al. Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer. Proc Natl Acad Sci USA 2013;110(14):E1301-10
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.14
-
-
Knight, J.F.1
Lesurf, R.2
Zhao, H.3
-
49
-
-
78549278133
-
Tyrosine phosphorylation profiling reveals the signaling network characteristics of basal breast cancer cells
-
Hochgräfe F, Zhang L, O'Toole SA, et al. Tyrosine phosphorylation profiling reveals the signaling network characteristics of basal breast cancer cells. Cancer Res 2010;70(22):9391-401
-
(2010)
Cancer Res
, vol.70
, Issue.22
, pp. 9391-9401
-
-
Hochgräfe, F.1
Zhang, L.2
O'Toole, S.A.3
-
50
-
-
31044441241
-
Gene expression profiling of breast cell lines identifies potential new basal markers
-
Charafe-Jauffret E, Ginestier C, Monville F, et al. Gene expression profiling of breast cell lines identifies potential new basal markers. Oncogene 2005;25(15):2273-84
-
(2005)
Oncogene
, vol.25
, Issue.15
, pp. 2273-2284
-
-
Charafe-Jauffret, E.1
Ginestier, C.2
Monville, F.3
-
51
-
-
50249182832
-
Protein profiling of human breast tumor cells identifies novel biomarkers associated with molecular subtypes
-
Gonçalves A, Charafe-Jauffret E, Bertucci F, et al. Protein profiling of human breast tumor cells identifies novel biomarkers associated with molecular subtypes. Mol Cell Proteomics 2008;7(8):1420-33
-
(2008)
Mol Cell Proteomics
, vol.7
, Issue.8
, pp. 1420-1433
-
-
Gonçalves, A.1
Charafe-Jauffret, E.2
Bertucci, F.3
-
52
-
-
79952278291
-
The met oncogene and basal-like breast cancer: Another culprit to watch out for?
-
Gastaldi S, Comoglio P, Trusolino L. The met oncogene and basal-like breast cancer: another culprit to watch out for? Breast Cancer Res 2010;12(4):208
-
(2010)
Breast Cancer Res
, vol.12
, Issue.4
, pp. 208
-
-
Gastaldi, S.1
Comoglio, P.2
Trusolino, L.3
-
53
-
-
84906237795
-
Met and HGF inhibition in triple-negative breast cancer cell lines
-
abstract 1066
-
Gaule P, Collins D, Walsh N, et al. Met and HGF inhibition in triple-negative breast cancer cell lines. J Clin Oncol 2011;31(Suppl):abstract 1066
-
(2011)
J Clin Oncol
, vol.31
, Issue.SUPPL.
-
-
Gaule, P.1
Collins, D.2
Walsh, N.3
-
54
-
-
44849139232
-
Met and c-src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cells
-
Mueller KL, Hunter LA, Ethier SP, et al. Met and c-src cooperate to compensate for loss of epidermal growth factor receptor kinase activity in breast cancer cells. Cancer Res 2008;68(9):3314-22
-
(2008)
Cancer Res
, vol.68
, Issue.9
, pp. 3314-3322
-
-
Mueller, K.L.1
Hunter, L.A.2
Ethier, S.P.3
-
55
-
-
77954405035
-
EGFR/Met association regulates EGFR TKI resistance in breast cancer
-
Mueller K, Yang Z, Haddad R, et al. EGFR/Met association regulates EGFR TKI resistance in breast cancer. J Mol Signal 2010;5(1):8
-
(2010)
J Mol Signal
, vol.5
, Issue.1
, pp. 8
-
-
Mueller, K.1
Yang, Z.2
Haddad, R.3
-
56
-
-
84863688063
-
Fibroblast-secreted hepatocyte growth factor mediates epidermal growth factor receptor tyrosine kinase inhibitor resistance in triple-negative breast cancers through paracrine activation of met
-
Mueller KL, Madden JM, Zoratti GL, et al. Fibroblast-secreted hepatocyte growth factor mediates epidermal growth factor receptor tyrosine kinase inhibitor resistance in triple-negative breast cancers through paracrine activation of met. Breast Cancer Res 2012;14(4):R104
-
(2012)
Breast Cancer Res
, vol.14
, Issue.4
-
-
Mueller, K.L.1
Madden, J.M.2
Zoratti, G.L.3
-
57
-
-
84906271469
-
Preclinical efficacy of the combination of met and src family kinase inhibitors in triple negative breast cancer
-
24 Suppl:abstract
-
Gartner E, Kim E, L Choi L, et al. Preclinical efficacy of the combination of met and src family kinase inhibitors in triple negative breast cancer. Cancer Res 2011;71(24 Suppl):abstract PD08-08
-
(2011)
Cancer Res
, vol.71
-
-
Gartner, E.1
Kim, E.2
Choi, L.L.3
-
58
-
-
62649165025
-
Profiling YB-1 target genes uncovers a new mechanism for MET receptor regulation in normal and malignant human mammary cells
-
Finkbeiner MR, Astanehe A, To K, et al. Profiling YB-1 target genes uncovers a new mechanism for MET receptor regulation in normal and malignant human mammary cells. Oncogene 2009;28(11):1421-31
-
(2009)
Oncogene
, vol.28
, Issue.11
, pp. 1421-1431
-
-
Finkbeiner, M.R.1
Astanehe, A.2
To, K.3
-
59
-
-
36549075549
-
Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy
-
Stratford A, Habibi G, Astanehe A, et al. Epidermal growth factor receptor (EGFR) is transcriptionally induced by the Y-box binding protein-1 (YB-1) and can be inhibited with Iressa in basal-like breast cancer, providing a potential target for therapy. Breast Cancer Res 2007;9(5):R61
-
(2007)
Breast Cancer Res
, vol.9
, Issue.5
-
-
Stratford, A.1
Habibi, G.2
Astanehe, A.3
-
60
-
-
79955420135
-
Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer
-
De Bacco F, Luraghi P, Medico E, et al. Induction of MET by ionizing radiation and its role in radioresistance and invasive growth of cancer. J Natl Cancer Inst 2011;103(8):645-61
-
(2011)
J Natl Cancer Inst
, vol.103
, Issue.8
, pp. 645-661
-
-
De Bacco, F.1
Luraghi, P.2
Medico, E.3
-
61
-
-
84855784852
-
C-MET protects breast cancer cells from apoptosis induced by sodium butyrate
-
Sun B, Liu R, Xiao Z, et al. c-MET protects breast cancer cells from apoptosis induced by sodium butyrate. PLoS One 2012;7(1):e30143
-
(2012)
PLoS One
, vol.7
, Issue.1
-
-
Sun, B.1
Liu, R.2
Xiao, Z.3
-
62
-
-
84855399564
-
HGF-induced PKCz activation increases functional CXCR4 expression in human breast cancer cells
-
Huang S, Ouyang N, Lin L, et al. HGF-induced PKCz activation increases functional CXCR4 expression in human breast cancer cells. PLoS One 2012;7(1):e29124
-
(2012)
PLoS One
, vol.7
, Issue.1
-
-
Huang, S.1
Ouyang, N.2
Lin, L.3
-
63
-
-
84855675936
-
Breast Cancer-Derived bone metastasis can be effectively reduced through specific c-MET inhibitor tivantinib (ARQ 197) and shRNA c-MET knockdown
-
Previdi S, Abbadessa G, Dalò F, et al. Breast Cancer-Derived bone metastasis can be effectively reduced through specific c-MET inhibitor tivantinib (ARQ 197) and shRNA c-MET knockdown. Mol Cancer Ther 2012;11(1):214-23
-
(2012)
Mol Cancer Ther
, vol.11
, Issue.1
, pp. 214-223
-
-
Previdi, S.1
Abbadessa, G.2
Dalò, F.3
-
64
-
-
0031906957
-
Agonistic monoclonal antibodies against the met receptor dissect the biological responses to HGF
-
Prat M, Crepaldi T, Pennacchietti S, et al. Agonistic monoclonal antibodies against the met receptor dissect the biological responses to HGF. J Cell Sci 1998;111(2):237-47
-
(1998)
J Cell Sci
, vol.111
, Issue.2
, pp. 237-247
-
-
Prat, M.1
Crepaldi, T.2
Pennacchietti, S.3
-
65
-
-
84881405670
-
Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent
-
Merchant M, Ma X, Maun HR, et al. Monovalent antibody design and mechanism of action of onartuzumab, a MET antagonist with anti-tumor activity as a therapeutic agent. Proc Natl Acad Sci USA 2013;110(32):E2987-96
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, Issue.32
-
-
Merchant, M.1
Ma, X.2
Maun, H.R.3
-
66
-
-
84890108571
-
Randomized phase II trial of onartuzumab in combination with erlotinib in patients with advanced non - Small-cell lung cancer
-
Spigel DR, Ervin TJ, Ramlau RA, et al. Randomized phase II trial of onartuzumab in combination with erlotinib in patients with advanced non - small-cell lung cancer. J Clin Oncol 2013;31(32):4105-14
-
(2013)
J Clin Oncol
, vol.31
, Issue.32
, pp. 4105-4114
-
-
Spigel, D.R.1
Ervin, T.J.2
Ramlau, R.A.3
-
67
-
-
84906276896
-
-
Media release [Internet]
-
Media release [Internet]. 2014. Available from: http://www. roche. com/media/media-releases/med-cor- 2014-03-03. htm
-
(2014)
-
-
-
68
-
-
84906278087
-
A randomized, phase II, multicenter, double-blind, placebo-controlled trial evaluating onartuzumab with or without bevacizumab in combination with weekly paclitaxel in locally recurrent or metastatic triple-negative breast cancer (TNBC)
-
abstract P2-16-01
-
Dieras V, Yardley D, Romieu G, et al. A randomized, phase II, multicenter, double-blind, placebo-controlled trial evaluating onartuzumab with or without bevacizumab in combination with weekly paclitaxel in locally recurrent or metastatic triple-negative breast cancer (TNBC). Cancer Res 2013;73:abstract P2-16-01
-
(2013)
Cancer Res
, vol.73
-
-
Dieras, V.1
Yardley, D.2
Romieu, G.3
-
69
-
-
84890253779
-
First-in-human dose escalation study of LY2875358 (LY), a bivalent MET antibody, as monotherapy and in combination with erlotinib (E) in patients with advanced cancer
-
abstract 1066
-
Goldman JW, Rosen LS, Algazi AP, et al. First-in-human dose escalation study of LY2875358 (LY), a bivalent MET antibody, as monotherapy and in combination with erlotinib (E) in patients with advanced cancer. J Clin Oncol 2013;31(Suppl): abstract 1066
-
(2013)
J Clin Oncol
, vol.31
, Issue.SUPPL.
-
-
Goldman, J.W.1
Rosen, L.S.2
Algazi, A.P.3
-
70
-
-
84906267257
-
Assay development for detecting cMET expression in circulating tumor cells (CTC), a potential patient tailoring marker for evaluation of cMET inhibitors
-
abstract 1738
-
Yan SB, Um SL, Peek VL, et al. Assay development for detecting cMET expression in circulating tumor cells (CTC), a potential patient tailoring marker for evaluation of cMET inhibitors. Cancer Res 2012;72(8 Suppl):abstract 1738
-
(2012)
Cancer Res
, vol.72
, Issue.8 SUPPL.
-
-
Yan, S.B.1
Um, S.L.2
Peek, V.L.3
-
71
-
-
84896390900
-
A phase II evaluation of AMG 102 (rilotumumab) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma: A gynecologic oncology group study
-
Martin LP, Sill M, Shahin MS, et al. A phase II evaluation of AMG 102 (rilotumumab) in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal carcinoma: a gynecologic oncology group study. Gynecol Oncol 2014;132(3):526-30
-
(2014)
Gynecol Oncol
, vol.132
, Issue.3
, pp. 526-530
-
-
Martin, L.P.1
Sill, M.2
Shahin, M.S.3
-
72
-
-
84877848587
-
Cytotoxic activity of tivantinib (ARQ 197) is not due solely to c-MET inhibition
-
Katayama R, Aoyama A, Yamori T, et al. Cytotoxic activity of tivantinib (ARQ 197) is not due solely to c-MET inhibition. Cancer Res 2013;73(10):3087-96
-
(2013)
Cancer Res
, vol.73
, Issue.10
, pp. 3087-3096
-
-
Katayama, R.1
Aoyama, A.2
Yamori, T.3
-
73
-
-
77953458271
-
ARQ 197, a novel and selective inhibitor of the human c-met receptor tyrosine kinase with antitumor activity
-
Munshi N, Jeay S, Li Y, et al. ARQ 197, a novel and selective inhibitor of the human c-met receptor tyrosine kinase with antitumor activity. Mol Cancer Ther 2010;9(6):1544-53
-
(2010)
Mol Cancer Ther
, vol.9
, Issue.6
, pp. 1544-1553
-
-
Munshi, N.1
Jeay, S.2
Li, Y.3
-
74
-
-
84898901879
-
A phase II study of foretinib in triple negative, recurrent/metastatic breast cancer: NCIC CTG trial IND. 197 (NCT01147484)
-
abstract 1036
-
Rayson D, Lupichuk SM, Chia SK, et al. A phase II study of foretinib in triple negative, recurrent/metastatic breast cancer: NCIC CTG trial IND. 197 (NCT01147484). J Clin Oncol 2012;30(Suppl):abstract 1036
-
(2012)
J Clin Oncol
, vol.30
, Issue.SUPPL.
-
-
Rayson, D.1
Lupichuk, S.M.2
Chia, S.K.3
-
75
-
-
84890281763
-
Companion biomarkers: Paving the pathway to personalized treatment for cancer
-
Duffy MJ, Crown J. Companion biomarkers: paving the pathway to personalized treatment for cancer. Clin Chem 2013;59(10):1447-56
-
(2013)
Clin Chem
, vol.59
, Issue.10
, pp. 1447-1456
-
-
Duffy, M.J.1
Crown, J.2
-
76
-
-
20144381957
-
Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry
-
Chung KY, Shia J, Kemeny NE, et al. Cetuximab shows activity in colorectal cancer patients with tumors that do not express the epidermal growth factor receptor by immunohistochemistry. J Clin Oncol 2005;23(9):1803-10
-
(2005)
J Clin Oncol
, vol.23
, Issue.9
, pp. 1803-1810
-
-
Chung, K.Y.1
Shia, J.2
Kemeny, N.E.3
-
77
-
-
84861203302
-
EGFR-mutated oncogene-addicted nonsmall cell lung cancer: Current trends and future prospects
-
Soria J, Mok TS, Cappuzzo F, et al. EGFR-mutated oncogene-addicted nonsmall cell lung cancer: current trends and future prospects. Cancer Treat Rev 2012;38(5):416-30
-
(2012)
Cancer Treat Rev
, vol.38
, Issue.5
, pp. 416-430
-
-
Soria, J.1
Mok, T.S.2
Cappuzzo, F.3
-
78
-
-
84905011727
-
Biomarker analyses from a placebocontrolled phase II study evaluating erlotinib ± onartuzumab in advanced non-small-cell lung cancer: MET expression levels are predictive of patient benefit
-
[Epub ahead of print]
-
Koeppen H, Yu W, Zha J, et al. Biomarker analyses from a placebocontrolled phase II study evaluating erlotinib ± onartuzumab in advanced non-small-cell lung cancer: MET expression levels are predictive of patient benefit. Clin Cancer Res 2014; [Epub ahead of print]
-
(2014)
Clin Cancer Res
-
-
Koeppen, H.1
Yu, W.2
Zha, J.3
-
79
-
-
1842428601
-
Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair
-
Huh C, Factor VM, Sánchez A, et al. Hepatocyte growth factor/c-met signaling pathway is required for efficient liver regeneration and repair. Proc Natl Acad Sci USA 2004;101(13):4477-82
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.13
, pp. 4477-4482
-
-
Huh, C.1
Factor, V.M.2
Sánchez, A.3
-
80
-
-
84906272801
-
-
http://clinicaltrials.gov/ [Internet]
-
Http://clinicaltrials. gov/[Internet]. 2014. Available from: http://clinicaltrials. gov/
-
(2014)
-
-
|