Prevalence of sleep deficiency and use of hypnotic drugs in astronauts before, during, and after spaceflight: AN observational study

The Lancet Neurology

Volumn 13, Issue 9, 2014, Pages 904-912

  Barger, Laura K ^a,b   Flynn Evans, Erin E ^a,b   Kubey, Alan ^a   Walsh, Lorcan ^a   Ronda, Joseph M ^a,b   Wang, Wei ^a,b   Wright, Kenneth P ^c   Czeisler, Charles A ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYPNOTIC AGENT; ESZOPICLONE; MELATONIN; QUETIAPINE; TEMAZEPAM; ZALEPLON; ZOLPIDEM; HYPNOTIC SEDATIVE AGENT; PYRIDINE DERIVATIVE;

ACTIMETRY; ADULT; ALERTNESS; ARTICLE; CONTROLLED STUDY; COSMONAUT; CREW MEMBER; DRUG USE; EXERCISE; FEMALE; HUMAN; HUMAN EXPERIMENT; LIGHT EXPOSURE; MALE; NIGHT SLEEP; NORMAL HUMAN; OBSERVATIONAL STUDY; PREVALENCE; PRIORITY JOURNAL; SLEEP DEPRIVATION; SLEEP PATTERN; SLEEP QUALITY; SLEEP TIME; SLEEP WAKING CYCLE; SPACE FLIGHT; VISUAL ANALOG SCALE; DRUG THERAPY; EPIDEMIOLOGY; MIDDLE AGED; PHYSIOLOGY; SLEEP; STATISTICS AND NUMERICAL DATA; TIME;

ACTIGRAPHY; ADULT; ASTRONAUTS; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; MALE; MIDDLE AGED; PREVALENCE; PYRIDINES; SLEEP; SLEEP DEPRIVATION; SPACE FLIGHT; TIME FACTORS;

EID: 84906272500     PISSN: 14744422     EISSN: 14744465     Source Type: Journal    
DOI: 10.1016/S1474-4422(14)70122-X     Document Type: Article

References (39)

1. Wide awake on the sea of tranquility National Aeronautics and Space Administration, (accessed April 12, 2013). http://www.nasa.gov/exploration/home/19jul_seaoftranquillity.html.
2. Sleep disorders National Heart, Lung, and Blood Institute, (accessed Aug 5, 2014). http://www.nhlbi.nih.gov/health/prof/sleep/index.htm.
3. Czeisler CA Impact of sleepiness and sleep deficiency on public health--utility of biomarkers. J Clin Sleep Med 2011, 7:S6-S8.
4. Weigmann DA, Shappell SA A human error approach to aviation accident analysis: the human factors analysis and classification system 2003, Ashgate Publishing Company, Aldershot.
5. Allen CS, Denham SA. International Space Station acoustics-a status report. 41st International Conference on Environmental Systems; Portland, OR; July 17-21, 2011. AIAA 2011-5128.
6. Stuster J Behavioral issues associated with long-duration space expeditions: review and analysis of astronaut journals. NASA/TM-2010-216130 2010, Johnson Space Center, Houston, TX.
7. Santy PA, Kapanka H, Davis JR, Stewart DF Analysis of sleep on Shuttle missions. Aviat Space Environ Med 1988, 59:1094-1097.
8. Monk TH, Buysse DJ, Billy BD, Kennedy KS, Willrich LM Sleep and circadian rhythms in four orbiting astronauts. J Biol Rhythms 1998, 13:188-201.
9. Dijk DJ, Neri DF, Wyatt JK, et al. Sleep, performance, circadian rhythms, and light-dark cycles during two space shuttle flights. Am J Physiol Regul Integr Comp Physiol 2001, 281:R1647-R1664.
10. Generic groundrules, requirements, and constraints part 1: strategic and tactical planning. Revision G incorporates DCN 063 2012, NASA International Space Station Program, Johnson Space Center, Houston, TX, NASA, NNJ10GA20B.
11. Kelly TH, Hienz RD, Zacone TJ, Wurster RM, Brady JV Crewmember performance before, during and after spaceflight. J Exp Anal Behav 2005, 84:227-241.
12. Gundel A, Polyakov VV, Zulley J The alteration of human sleep and circadian rhythms during spaceflight. J Sleep Res 1997, 6:1-8.
13. Achenbach J The skies. The limits. The Washington Post (accessed Oct 14, 2013). http://www.washingtonpost.com/sf/national/2013/09/14/the-skies-the-limits/?hpid=z5.
14. Ertel KA, Berkman LF, Buxton OM Socioeconomic status, occupational characteristics and sleep duration in African/Caribbean immigrants and US white health care workers. Sleep 2011, 34:509-518.
15. Berkman LF, Buxton O, Ertel K, Okechukwu C Managers' practices related to work-family balance precict employee cardiovascular risk and sleep duration in extended care settings. J Occup Health Psychol 2010, 15:316-329.
16. Rupp TL, Wesensten NJ, Balkin TJ Sleep history affects task acquisition during subsequent sleep restriction and recovery. J Sleep Res 2010, 19:289-297.
17. Kecklund G, Akerstedt T Apprehension of the subsequent working day is associated with a low amount of slow wave sleep. Biol Psychol 2004, 66:169-176.
18. Akerstedt T, Kecklund G, Ingre M, Lekander M, Axelsson J Sleep homeostasis during repeated sleep restriction and recovery: support from EEG dynamics. Sleep 2009, 32:217-222.
19. Hawkins W, Zieglschmid J Clinical aspects of crew health. SP-368 Biomedical Results of Apollo 1975, 43-82. Lyndon B Johnson Space Center, Washington, DC. R. Johnston, L. Dietlein, C. Berry (Eds.).
20. Putcha L, Berens KL, Marshburn TH, Ortega HJ, Billica RD Pharmaceutical use by US astronauts on space shuttle missions. Aviat Space Environ Med 1999, 70:705-708.
21. Bertisch SM, Herzig SJ, Winkelman JW, Buettner C National use of prescription medicatins for insomnia: NHANES 1999-2010. Sleep 2014, 37:343-349.
22. Zolpidem (package insert) 2012, Bridgewater, Sanofi-Aventis.
23. Frey DJ, Ortega JD, Wiseman C, Farley CT, Wright KP Influence of zolpidem on balance and cognition during nighttime awakening: a randomized placebo controlled trial. J Am Geriatr Soc 2011, 59:73-81.
24. Some sleep drugs can impair driving US Food and Drug Administration (FDA), (accessed May 17, 2013). http://www.fda.gov/forconsumers/consumerupdates/ucm322743.htm.
25. Hoque R, Chesson AL Zolpidem-induced sleepwalking, sleep related eating disorder, and sleep-driving; fluorine-18-flourodeoxyglucose positron emission tomography analysis, and a literature review of other unexpected clinical effects of zolpiem. J Clin Sleep Med 2009, 5:471-476.
26. Clay E, Falissard B, Moore N, Toumi M Contribution of prolonged-release melatonin and anti-benzodiazepine campaigns to the reduction of benzodiazepine and Z-drugs consumption in nine European countries. Eur J Clin Pharmacol 2013, 69:1-10.
27. Victorri-Vigneau C, Dailly E, Veyrac G, Jolliet P Evidence of zolpidem abuse and dependence: results of the French Centre for Evaluation and Information on Pharmacodependence (CEIP) network survey. Br J Clin Pharmacol 2007, 64:198-209.
28. Monk TH, Buysse DJ, Rose LR Wrist actigraphic measures of sleep in space. Sleep 1999, 22:948-954.
29. Tietze K, Putcha L Factors affecting drug bioavailability in space. J Clin Psychopharmacol 1994, 34:671-676.
30. Du B, Daniels VR, Vaksman Z, Boyd JL, Crady C, Putcha L Evaluation of physical and chemical changes in pharmaceuticals flown on space missions. AAPS J 2011, 13:299-308.
31. Putcha L, Cintron NM Pharmacokinetic consequences of spaceflight. Ann NY Acad Sci 1991, 618:615-618.
32. Sleep disorders and sleep deprivation: an unmet public health problem 2006, Institute of Medicine, National Academies Press, Washington, DC. H.R. Colten, B.M. Alteveogt (Eds.).
33. Resident duty hours: enhancing sleep, supervision, and safety 2008, Institute of Medicine, National Academies Press, Washington, DC. C. Ulmer, D.M. Wolman, M.M.E. Johns (Eds.).
34. Hursh SR, Raslear TG, Kaye AS, Farzone JF Validation and calibration of a fatigue assessment tool for railroad work schedules, summary report 2006, Department of Transportation Federal Railroad Administration, Washington, DC.
35. Ayas NT, Barger LK, Cade BE, et al. Extended work duration and the risk of self-reported percutaneous injuries in interns. JAMA 2006, 296:1055-1062.
36. Barger LK, Cade BE, Ayas NT, et al. Extended work shifts and the risk of motor vehicle crashes among interns. N Engl J Med 2005, 352:125-134.
37. Barger LK, Ayas NT, Cade BE, et al. Impact of extended-duration shifts on medical errors, adverse events, and attentional failures. PLoS Med 2006, 3:e487.
38. Landrigan CP, Rothschild JM, Cronin JW, et al. Effect of reducing interns' work hours on serious medical errors in intensive care units. N Engl J Med 2004, 351:1838-1848.
39. Lockley SW, Cronin JW, Evans EE, et al. Effect of reducing interns' weekly work hours on sleep and attentional failures. N Engl J Med 2004, 351:1829-1837.