Risk factors for central neck lymph node metastasis of clinically noninvasive, node-negative papillary thyroid microcarcinoma

American Journal of Surgery

Volumn 208, Issue 3, 2014, Pages 412-418

  Park, Joon Pyo ^a   Roh, Jong Lyel ^a   Lee, Jeong Hyun ^a   Baek, Jung Hwan ^a   Gong, Gyungyub ^a   Cho, Kyung Ja ^a   Choi, Seung Ho ^a   Nam, Soon Yuhl ^a   Kim, Sang Yoon ^a,b  

^a University of Ulsan College of Medicine   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

Author keywords

Central neck; Lymph node dissection; Papillary thyroid carcinoma; Predictive factors; Subclinical lymph node metastasis

Indexed keywords

ADULT; AGED; ARTICLE; CANCER SIZE; CERVICAL LYMPH NODE; CERVICAL LYMPH NODE METASTASIS; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; HYPOCALCEMIA; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MORBIDITY; NECK DISSECTION; PAPILLARY THYROID MICROCARCINOMA; POSTOPERATIVE COMPLICATION; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; REGIONAL METASTASIS; RISK ASSESSMENT; THYROID CARCINOMA; THYROIDECTOMY; VOCAL CORD PARALYSIS;

CENTRAL NECK; LYMPH NODE DISSECTION; PAPILLARY THYROID CARCINOMA; PREDICTIVE FACTORS; SUBCLINICAL LYMPH NODE METASTASIS;

ADULT; AGED; CARCINOMA; CARCINOMA, PAPILLARY; FEMALE; FOLLOW-UP STUDIES; HUMANS; LOGISTIC MODELS; LYMPHATIC METASTASIS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NECK DISSECTION; NEOPLASM INVASIVENESS; RISK FACTORS; THYROID NEOPLASMS; THYROIDECTOMY; TUMOR BURDEN;

EID: 84906270312     PISSN: 00029610     EISSN: 18791883     Source Type: Journal    
DOI: 10.1016/j.amjsurg.2013.10.032     Document Type: Article

References (31)

1. Y. Ito, C. Tomoda, and T. Uruno et al. Clinical significance of metastasis to the central compartment from papillary microcarcinoma of the thyroid World J Surg 30 2006 91 99
2. L. Davies, and H.G. Welch Increasing incidence of thyroid cancer in the United States, 1973-2002 JAMA 295 2006 2164 2167
3. A.Y. Chen, A. Jemal, and E.M. Ward Increasing incidence of differentiated thyroid cancer in the United States, 1988-2005 Cancer 115 2009 3801 3807
4. N. Wada, Q.Y. Duh, and K. Sugino et al. Lymph node metastasis from 259 papillary thyroid microcarcinomas: frequency, pattern of occurrence and recurrence, and optimal strategy for neck dissection Ann Surg 237 2003 399 407
5. J.L. Roh, J.M. Kim, and C.I. Park Central cervical nodal metastasis from papillary thyroid microcarcinoma: pattern and factors predictive of nodal metastasis Ann Surg Oncol 15 2008 2482 2486
6. Y.C. Lim, E.C. Choi, and Y.H. Yoon et al. Central lymph node metastases in unilateral papillary thyroid microcarcinoma Br J Surg 96 2009 253 257
7. I.D. Hay, M.E. Hutchinson, and T. Gonzalez-Losada et al. Papillary thyroid microcarcinoma: a study of 900 cases observed in a 60-year period Surgery 144 2008 980 987
8. A. Pisanu, I. Reccia, and O. Nardello et al. Risk factors for nodal metastasis and recurrence among patients with papillary thyroid microcarcinoma: differences in clinical relevance between nonincidental and incidental tumors World J Surg 33 2009 460 468
9. C.I. Lundgren, P. Hall, and P.W. Dickman et al. Clinically significant prognostic factors for differentiated thyroid carcinoma: a population-based, nested case-control study Cancer 106 2006 524 531
10. D.S. Cooper, G.M. Doherty, and B.R. Haugen et al. Revised American Thyroid Association management guidelines for patients with thyroid nodules and differentiated thyroid cancer Thyroid 19 2009 1167 1214
11. C.C. Solorzano, D.M. Carneiro, and M. Ramirez et al. Surgeon-performed ultrasound in the management of thyroid malignancy Am Surg 70 2004 576 580
12. H.S. Hwang, and L.A. Orloff Efficacy of preoperative neck ultrasound in the detection of cervical lymph node metastasis from thyroid cancer Laryngoscope 121 2011 487 491
13. Y.K. So, Y.I. Son, and S.D. Hong et al. Subclinical lymph node metastasis in papillary thyroid microcarcinoma: a study of 551 resections Surgery 148 2010 526 531
14. K.E. Kim, E.K. Kim, and J.H. Yoon et al. Preoperative prediction of central lymph node metastasis in thyroid papillary microcarcinoma using clinicopathologic and sonographic features World J Surg 37 2013 385 391
15. L. Zhang, W.J. Wei, and Q.H. Ji et al. Risk factors for neck nodal metastasis in papillary thyroid microcarcinoma: a study of 1066 patients J Clin Endocrinol Metab 97 2012 1250 1257
16. Q. Zhao, J. Ming, and C. Liu et al. Multifocality and total tumor diameter predict central neck lymph node metastases in papillary thyroid microcarcinoma Ann Surg Oncol 20 2013 746 752
17. W.J. Moon, S.L. Jung, and J.H. Lee et al. Benign and malignant nodules: US differentiation-multicenter retrospective study Radiology 247 2008 762 770
18. J. Lee, Y. Rhee, and S. Lee et al. Frequent, aggressive behaviors of thyroid microcarcinomas in Korean patients Endocr J 53 2006 627 632
19. B. Abboud, R. Daher, and G. Sleilaty et al. Are papillary microcarcinomas of the thyroid gland revealed by cervical adenopathy more aggressive? Am Surg 76 2010 306 311
20. S.M. Chow, S.C. Law, and J.K. Chan et al. Papillary microcarcinoma of the thyroid - Prognostic significance of lymph node metastasis and multifocality Cancer 98 2003 31 40
21. G. Mercante, A. Frasoldati, and C. Pedroni et al. Prognostic factors affecting neck lymph node recurrence and distant metastasis in papillary microcarcinoma of the thyroid: results of a study in 445 patients Thyroid 19 2009 707 716
22. M.P. Connor, D. Wells, and C.E. Schmalbach Variables predictive of bilateral occult papillary microcarcinoma following total thyroidectomy Otolaryngol Head Neck Surg 144 2011 210 215
23. E. Dunki-Jacobs, K. Grannan, and S. McDonough et al. Clinically unsuspected papillary microcarcinomas of the thyroid: a common finding with favorable biology? Am J Surg 203 2012 140 144
24. H. Mazeh, Y. Samet, and D. Hochstein et al. Multifocality in well-differentiated thyroid carcinomas calls for total thyroidectomy Am J Surg 201 2011 770 775
25. L. Jovanovic, B. Delahunt, and B. McIver et al. Distinct genetic changes characterise multifocality and diverse histological subtypes in papillary thyroid carcinoma Pathology 42 2010 524 533
26. C.P. Lombardi, R. Bellantone, and C. De Crea et al. Papillary thyroid microcarcinoma: extrathyroidal extension, lymph node metastases, and risk factors for recurrence in a high prevalence of goiter area World J Surg 34 2010 1214 1221
27. J.L. Roh, and C.I. Park Sentinel lymph node biopsy as guidance for central neck dissection in patients with papillary thyroid carcinoma Cancer 113 2008 1527 1531
28. S.M. Hyun, H.Y. Song, and S.Y. Kim et al. Impact of combined prophylactic unilateral central neck dissection and hemithyroidectomy in patients with papillary thyroid microcarcinoma Ann Surg Oncol 19 2012 591 596
29. Y.K. So, M.Y. Seo, and Y.I. Son Prophylactic central lymph node dissection for clinically node-negative papillary thyroid microcarcinoma: influence on serum thyroglobulin level, recurrence rate, and postoperative complications Surgery 151 2012 192 198
30. T. Zetoune, X. Keutgen, and D. Buitrago et al. Prophylactic central neck dissection and local recurrence in papillary thyroid cancer: a meta-analysis Ann Surg Oncol 17 2010 3287 3293
31. E.L. Mazzaferri, G.M. Doherty, and D.L. Steward The pros and cons of prophylactic central compartment lymph node dissection for papillary thyroid carcinoma Thyroid 19 2009 683 689