-
1
-
-
79955096411
-
MYC and aggressive B-cell lymphomas
-
Slack GW, Gascoyne RD,. MYC and aggressive B-cell lymphomas. Adv Anat Pathol 2011; 18: 219-28.
-
(2011)
Adv Anat Pathol
, vol.18
, pp. 219-228
-
-
Slack, G.W.1
Gascoyne, R.D.2
-
2
-
-
79958095463
-
Clinical and biological implications of MYC activation: A common difference between MGUS and newly diagnosed multiple myeloma
-
Chng WJ, Huang GF, Chung TH, et al. Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma. Leukemia 2011; 25: 1026-35.
-
(2011)
Leukemia
, vol.25
, pp. 1026-1035
-
-
Chng, W.J.1
Huang, G.F.2
Chung, T.H.3
-
3
-
-
0035839844
-
Translocations involving c-myc and c-myc function
-
Boxer LM, Dang CV,. Translocations involving c-myc and c-myc function. Oncogene 2001; 20: 5595-610.
-
(2001)
Oncogene
, vol.20
, pp. 5595-5610
-
-
Boxer, L.M.1
Dang, C.V.2
-
4
-
-
4644222793
-
High response rate and manageable toxicity with an intensive, short-term chemotherapy programme for Burkitt's lymphoma in adults
-
Di Nicola M, Carlo-Stella C, Mariotti J, et al. High response rate and manageable toxicity with an intensive, short-term chemotherapy programme for Burkitt's lymphoma in adults. Br J Haematol 2004; 126: 815-20.
-
(2004)
Br J Haematol
, vol.126
, pp. 815-820
-
-
Di Nicola, M.1
Carlo-Stella, C.2
Mariotti, J.3
-
6
-
-
77954752069
-
Rearrangement of MYC is associated with poor prognosis in patients with diffuse large B-cell lymphoma treated in the era of rituximab
-
Barrans S, Crouch S, Smith A, et al. Rearrangement of MYC is associated with poor prognosis in patients with diffuse large B-cell lymphoma treated in the era of rituximab. J Clin Oncol 2010; 28: 3360-5.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3360-3365
-
-
Barrans, S.1
Crouch, S.2
Smith, A.3
-
7
-
-
84861211721
-
MYC+ diffuse large B-cell lymphoma is not salvaged by classical R-ICE or R-DHAP followed by BEAM plus autologous stem cell transplantation
-
Cuccuini W, Briere J, Mounier N, et al. MYC+ diffuse large B-cell lymphoma is not salvaged by classical R-ICE or R-DHAP followed by BEAM plus autologous stem cell transplantation. Blood 2012; 119: 4619-24.
-
(2012)
Blood
, vol.119
, pp. 4619-4624
-
-
Cuccuini, W.1
Briere, J.2
Mounier, N.3
-
8
-
-
54449085259
-
Five-gene model to predict survival in mantle-cell lymphoma using frozen or formalin-fixed, paraffin-embedded tissue
-
Hartmann E, Fernandez V, Moreno V, et al. Five-gene model to predict survival in mantle-cell lymphoma using frozen or formalin-fixed, paraffin-embedded tissue. J Clin Oncol 2008; 26: 4966-72.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4966-4972
-
-
Hartmann, E.1
Fernandez, V.2
Moreno, V.3
-
9
-
-
0023854161
-
The e mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells
-
Harris AW, Pinkert CA, Crawford M, et al. The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells. J Exp Med 1988; 167: 353-71.
-
(1988)
J Exp Med
, vol.167
, pp. 353-371
-
-
Harris, A.W.1
Pinkert, C.A.2
Crawford, M.3
-
10
-
-
0033180211
-
Reversible tumorigenesis by MYC in hematopoietic lineages
-
Felsher DW, Bishop JM,. Reversible tumorigenesis by MYC in hematopoietic lineages. Mol Cell 1999; 4: 199-207.
-
(1999)
Mol Cell
, vol.4
, pp. 199-207
-
-
Felsher, D.W.1
Bishop, J.M.2
-
11
-
-
0038492517
-
A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells
-
Li Z, Van Calcar S, Qu C, et al. A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells. Proc Natl Acad Sci USA 2003; 100: 8164-9.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 8164-8169
-
-
Li, Z.1
Van Calcar, S.2
Qu, C.3
-
12
-
-
34547599505
-
PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation
-
Zippo A, De Robertis A, Serafini R, Oliviero S,. PIM1-dependent phosphorylation of histone H3 at serine 10 is required for MYC-dependent transcriptional activation and oncogenic transformation. Nat Cell Biol 2007; 9: 932-44.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 932-944
-
-
Zippo, A.1
De Robertis, A.2
Serafini, R.3
Oliviero, S.4
-
13
-
-
45549095542
-
Myc-mediated transcriptional repression by recruitment of histone deacetylase
-
Kurland JF, Tansey WP,. Myc-mediated transcriptional repression by recruitment of histone deacetylase. Cancer Res 2008; 68: 3624-9.
-
(2008)
Cancer Res
, vol.68
, pp. 3624-3629
-
-
Kurland, J.F.1
Tansey, W.P.2
-
14
-
-
84867606040
-
Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-cell lymphomas
-
Zhang X, Zhao X, Fiskus W, et al. Coordinated silencing of MYC-mediated miR-29 by HDAC3 and EZH2 as a therapeutic target of histone modification in aggressive B-cell lymphomas. Cancer Cell 2012; 22: 506-23.
-
(2012)
Cancer Cell
, vol.22
, pp. 506-523
-
-
Zhang, X.1
Zhao, X.2
Fiskus, W.3
-
15
-
-
84862315462
-
Myc represses miR-15a/miR-16-1 expression through recruitment of HDAC3 in mantle cell and other non-Hodgkin B-cell lymphomas
-
Zhang X, Chen X, Lin J, et al. Myc represses miR-15a/miR-16-1 expression through recruitment of HDAC3 in mantle cell and other non-Hodgkin B-cell lymphomas. Oncogene 2012; 31: 3002-8.
-
(2012)
Oncogene
, vol.31
, pp. 3002-3008
-
-
Zhang, X.1
Chen, X.2
Lin, J.3
-
16
-
-
84890430327
-
Disruption of the MYC-miRNA-EZH2 loop to suppress aggressive B-cell lymphoma survival and clonogenicity
-
Zhao X, Lwin T, Zhang X, et al. Disruption of the MYC-miRNA-EZH2 loop to suppress aggressive B-cell lymphoma survival and clonogenicity. Leukemia 2013; 27: 2341-50.
-
(2013)
Leukemia
, vol.27
, pp. 2341-2350
-
-
Zhao, X.1
Lwin, T.2
Zhang, X.3
-
17
-
-
0034653998
-
C-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover
-
Bahram F, von der Lehr N, Cetinkaya C, et al. c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover. Blood 2000; 95: 2104-10.
-
(2000)
Blood
, vol.95
, pp. 2104-2110
-
-
Bahram, F.1
Von Der Lehr, N.2
Cetinkaya, C.3
-
18
-
-
0036781812
-
C-MYC: More than just a matter of life and death
-
Pelengaris S, Khan M, Evan G,. c-MYC: more than just a matter of life and death. Nat Rev Cancer 2002; 2: 764-76.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 764-776
-
-
Pelengaris, S.1
Khan, M.2
Evan, G.3
-
19
-
-
30344482578
-
C-Myc inhibition negatively impacts lymphoma growth
-
discussion 11
-
Gomez-Curet I, Perkins RS, Bennett R, et al. c-Myc inhibition negatively impacts lymphoma growth. J Pediatr Surg 2006; 41: 207-11; discussion 11.
-
(2006)
J Pediatr Surg
, vol.41
, pp. 207-211
-
-
Gomez-Curet, I.1
Perkins, R.S.2
Bennett, R.3
-
20
-
-
80051788362
-
Histone deacetylase inhibitors sensitize human non-small cell lung cancer cells to ionizing radiation through acetyl p53-mediated c-myc down-regulation
-
Seo SK, Jin HO, Woo SH, et al. Histone deacetylase inhibitors sensitize human non-small cell lung cancer cells to ionizing radiation through acetyl p53-mediated c-myc down-regulation. J Thorac Oncol 2011; 6: 1313-9.
-
(2011)
J Thorac Oncol
, vol.6
, pp. 1313-1319
-
-
Seo, S.K.1
Jin, H.O.2
Woo, S.H.3
-
21
-
-
79957913253
-
Combining histone deacetylase inhibitor vorinostat with aurora kinase inhibitors enhances lymphoma cell killing with repression of c-Myc, hTERT, and microRNA levels
-
Kretzner L, Scuto A, Dino PM, et al. Combining histone deacetylase inhibitor vorinostat with aurora kinase inhibitors enhances lymphoma cell killing with repression of c-Myc, hTERT, and microRNA levels. Cancer Res 2011; 71: 3912-20.
-
(2011)
Cancer Res
, vol.71
, pp. 3912-3920
-
-
Kretzner, L.1
Scuto, A.2
Dino, P.M.3
-
22
-
-
61449238163
-
Repressing the repressor: A new mode of MYC action in lymphomagenesis
-
Sander S, Bullinger L,. Repressing the repressor: a new mode of MYC action in lymphomagenesis. Cell Cycle 2009; 8: 556-9.
-
(2009)
Cell Cycle
, vol.8
, pp. 556-559
-
-
Sander, S.1
Bullinger, L.2
-
23
-
-
35449003175
-
MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells
-
Sampson VB, Rong NH, Han J, et al. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. Cancer Res 2007; 67: 9762-70.
-
(2007)
Cancer Res
, vol.67
, pp. 9762-9770
-
-
Sampson, V.B.1
Rong, N.H.2
Han, J.3
-
24
-
-
68149165414
-
HuR recruits let-7/RISC to repress c-Myc expression
-
Kim HH, Kuwano Y, Srikantan S, et al. HuR recruits let-7/RISC to repress c-Myc expression. Genes Dev 2009; 23: 1743-8.
-
(2009)
Genes Dev
, vol.23
, pp. 1743-1748
-
-
Kim, H.H.1
Kuwano, Y.2
Srikantan, S.3
-
25
-
-
48549094467
-
C-Myc and eIF4F are components of a feedforward loop that links transcription and translation
-
Lin CJ, Cencic R, Mills JR, et al. c-Myc and eIF4F are components of a feedforward loop that links transcription and translation. Cancer Res 2008; 68: 5326-34.
-
(2008)
Cancer Res
, vol.68
, pp. 5326-5334
-
-
Lin, C.J.1
Cencic, R.2
Mills, J.R.3
-
26
-
-
78549275158
-
Improved clinical outcome in indolent B-cell lymphoma patients vaccinated with autologous tumor cells experiencing immunogenic death
-
Zappasodi R, Pupa SM, Ghedini GC, et al. Improved clinical outcome in indolent B-cell lymphoma patients vaccinated with autologous tumor cells experiencing immunogenic death. Cancer Res 2010; 70: 9062-72.
-
(2010)
Cancer Res
, vol.70
, pp. 9062-9072
-
-
Zappasodi, R.1
Pupa, S.M.2
Ghedini, G.C.3
-
27
-
-
80054836022
-
Serological identification of HSP105 as a novel non-Hodgkin lymphoma therapeutic target
-
Zappasodi R, Bongarzone I, Ghedini GC, et al. Serological identification of HSP105 as a novel non-Hodgkin lymphoma therapeutic target. Blood 2011; 118: 4421-30.
-
(2011)
Blood
, vol.118
, pp. 4421-4430
-
-
Zappasodi, R.1
Bongarzone, I.2
Ghedini, G.C.3
-
28
-
-
79958093024
-
Proapoptotic signaling activity of the anti-CD40 monoclonal antibody dacetuzumab circumvents multiple oncogenic transformation events and chemosensitizes NHL cells
-
Lewis TS, McCormick RS, Stone IJ, et al. Proapoptotic signaling activity of the anti-CD40 monoclonal antibody dacetuzumab circumvents multiple oncogenic transformation events and chemosensitizes NHL cells. Leukemia 2011; 25: 1007-16.
-
(2011)
Leukemia
, vol.25
, pp. 1007-1016
-
-
Lewis, T.S.1
McCormick, R.S.2
Stone, I.J.3
-
29
-
-
40749113668
-
Selective anti-leukaemic activity of low-dose histone deacetylase inhibitor ITF2357 on AML1/ETO-positive cells
-
Barbetti V, Gozzini A, Rovida E, et al. Selective anti-leukaemic activity of low-dose histone deacetylase inhibitor ITF2357 on AML1/ETO-positive cells. Oncogene 2008; 27: 1767-78.
-
(2008)
Oncogene
, vol.27
, pp. 1767-1778
-
-
Barbetti, V.1
Gozzini, A.2
Rovida, E.3
-
30
-
-
60149091189
-
Regulation of translation initiation in eukaryotes: Mechanisms and biological targets
-
Sonenberg N, Hinnebusch AG,. Regulation of translation initiation in eukaryotes: mechanisms and biological targets. Cell 2009; 136: 731-45.
-
(2009)
Cell
, vol.136
, pp. 731-745
-
-
Sonenberg, N.1
Hinnebusch, A.G.2
-
31
-
-
19344374597
-
Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival
-
Hammerman PS, Fox CJ, Birnbaum MJ, et al. Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival. Blood 2005; 105: 4477-83.
-
(2005)
Blood
, vol.105
, pp. 4477-4483
-
-
Hammerman, P.S.1
Fox, C.J.2
Birnbaum, M.J.3
-
32
-
-
78650606450
-
For better or for worse: The role of Pim oncogenes in tumorigenesis
-
Nawijn MC, Alendar A, Berns A,. For better or for worse: the role of Pim oncogenes in tumorigenesis. Nat Rev Cancer 2011; 11: 23-34.
-
(2011)
Nat Rev Cancer
, vol.11
, pp. 23-34
-
-
Nawijn, M.C.1
Alendar, A.2
Berns, A.3
-
33
-
-
80053651202
-
Targeting MYC dependence in cancer by inhibiting BET bromodomains
-
Mertz JA, Conery AR, Bryant BM, et al. Targeting MYC dependence in cancer by inhibiting BET bromodomains. Proc Natl Acad Sci USA 2011; 108: 16669-74.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 16669-16674
-
-
Mertz, J.A.1
Conery, A.R.2
Bryant, B.M.3
-
34
-
-
84856069665
-
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis
-
Kessler JD, Kahle KT, Sun T, et al. A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis. Science 2012; 335: 348-53.
-
(2012)
Science
, vol.335
, pp. 348-353
-
-
Kessler, J.D.1
Kahle, K.T.2
Sun, T.3
-
35
-
-
79955761350
-
The role of histone deacetylase 7 (HDAC7) in cancer cell proliferation: Regulation on c-Myc
-
Zhu C, Chen Q, Xie Z, et al. The role of histone deacetylase 7 (HDAC7) in cancer cell proliferation: regulation on c-Myc. J Mol Med 2011; 89: 279-89.
-
(2011)
J Mol Med
, vol.89
, pp. 279-289
-
-
Zhu, C.1
Chen, Q.2
Xie, Z.3
-
36
-
-
33845353746
-
Evidence that microRNAs are associated with translating messenger RNAs in human cells
-
Maroney PA, Yu Y, Fisher J, et al. Evidence that microRNAs are associated with translating messenger RNAs in human cells. Nat Struct Mol Biol 2006; 13: 1102-7.
-
(2006)
Nat Struct Mol Biol
, vol.13
, pp. 1102-1107
-
-
Maroney, P.A.1
Yu, Y.2
Fisher, J.3
-
37
-
-
48249119199
-
The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene
-
Kong YW, Cannell IG, de Moor CH, et al. The mechanism of micro-RNA-mediated translation repression is determined by the promoter of the target gene. Proc Natl Acad Sci USA 2008; 105: 8866-71.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 8866-8871
-
-
Kong, Y.W.1
Cannell, I.G.2
De Moor, C.H.3
-
38
-
-
61349112251
-
MYC stimulates EZH2 expression by repression of its negative regulator miR-26a
-
Sander S, Bullinger L, Klapproth K, et al. MYC stimulates EZH2 expression by repression of its negative regulator miR-26a. Blood 2008; 112: 4202-12.
-
(2008)
Blood
, vol.112
, pp. 4202-4212
-
-
Sander, S.1
Bullinger, L.2
Klapproth, K.3
-
39
-
-
84877815031
-
EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation
-
Beguelin W, Popovic R, Teater M, et al. EZH2 is required for germinal center formation and somatic EZH2 mutations promote lymphoid transformation. Cancer Cell 2013; 23: 677-92.
-
(2013)
Cancer Cell
, vol.23
, pp. 677-692
-
-
Beguelin, W.1
Popovic, R.2
Teater, M.3
-
40
-
-
84863012417
-
Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia
-
Sampath D, Liu C, Vasan K, et al. Histone deacetylases mediate the silencing of miR-15a, miR-16, and miR-29b in chronic lymphocytic leukemia. Blood 2012; 119: 1162-72.
-
(2012)
Blood
, vol.119
, pp. 1162-1172
-
-
Sampath, D.1
Liu, C.2
Vasan, K.3
-
41
-
-
80054845323
-
Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma
-
Schatz JH, Oricchio E, Wolfe AL, et al. Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma. J Exp Med 2011; 208.
-
(2011)
J Exp Med
, vol.208
-
-
Schatz, J.H.1
Oricchio, E.2
Wolfe, A.L.3
-
42
-
-
49649127162
-
Pim kinase-dependent inhibition of c-Myc degradation
-
Zhang Y, Wang Z, Li X, et al. Pim kinase-dependent inhibition of c-Myc degradation. Oncogene 2008; 27: 4809-19.
-
(2008)
Oncogene
, vol.27
, pp. 4809-4819
-
-
Zhang, Y.1
Wang, Z.2
Li, X.3
-
43
-
-
33845226377
-
Phosphoinositide 3-kinase activation in late G1 is required for c-Myc stabilization and S phase entry
-
Kumar A, Marques M, Carrera AC,. Phosphoinositide 3-kinase activation in late G1 is required for c-Myc stabilization and S phase entry. Mol Cell Biol 2006; 26: 9116-25.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 9116-9125
-
-
Kumar, A.1
Marques, M.2
Carrera, A.C.3
-
44
-
-
84865114403
-
Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis
-
Sander S, Calado DP, Srinivasan L, et al. Synergy between PI3K signaling and MYC in Burkitt lymphomagenesis. Cancer Cell 2012; 22: 167-79.
-
(2012)
Cancer Cell
, vol.22
, pp. 167-179
-
-
Sander, S.1
Calado, D.P.2
Srinivasan, L.3
-
45
-
-
84861171712
-
Targeting synthetic lethal interactions between Myc and the eIF4F complex impedes tumorigenesis
-
Lin CJ, Nasr Z, Premsrirut PK, et al. Targeting synthetic lethal interactions between Myc and the eIF4F complex impedes tumorigenesis. Cell Rep 2012; 1: 325-33.
-
(2012)
Cell Rep
, vol.1
, pp. 325-333
-
-
Lin, C.J.1
Nasr, Z.2
Premsrirut, P.K.3
-
46
-
-
81555196341
-
PIM2 inhibition as a rational therapeutic approach in B-cell lymphoma
-
Gomez-Abad C, Pisonero H, Blanco-Aparicio C, et al. PIM2 inhibition as a rational therapeutic approach in B-cell lymphoma. Blood 2011; 118: 5517-27.
-
(2011)
Blood
, vol.118
, pp. 5517-5527
-
-
Gomez-Abad, C.1
Pisonero, H.2
Blanco-Aparicio, C.3
-
47
-
-
57049101684
-
Ki67 and PIM1 expression predict outcome in mantle cell lymphoma treated with high dose therapy, stem cell transplantation and rituximab: A Cancer and Leukemia Group B 59909 correlative science study
-
Hsi ED, Jung SH, Lai R, et al. Ki67 and PIM1 expression predict outcome in mantle cell lymphoma treated with high dose therapy, stem cell transplantation and rituximab: a Cancer and Leukemia Group B 59909 correlative science study. Leuk Lymphoma 2008; 49: 2081-90.
-
(2008)
Leuk Lymphoma
, vol.49
, pp. 2081-2090
-
-
Hsi, E.D.1
Jung, S.H.2
Lai, R.3
-
48
-
-
84867051939
-
Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics
-
Schmitz R, Young RM, Ceribelli M, et al. Burkitt lymphoma pathogenesis and therapeutic targets from structural and functional genomics. Nature 2012; 490: 116-20.
-
(2012)
Nature
, vol.490
, pp. 116-120
-
-
Schmitz, R.1
Young, R.M.2
Ceribelli, M.3
-
49
-
-
52649133274
-
HDAC6 inhibition enhances 17-AAG-mediated abrogation of hsp90 chaperone function in human leukemia cells
-
Rao R, Fiskus W, Yang Y, et al. HDAC6 inhibition enhances 17-AAG-mediated abrogation of hsp90 chaperone function in human leukemia cells. Blood 2008; 112: 1886-93.
-
(2008)
Blood
, vol.112
, pp. 1886-1893
-
-
Rao, R.1
Fiskus, W.2
Yang, Y.3
-
50
-
-
79957933972
-
Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat)
-
Furlan A, Monzani V, Reznikov LL, et al. Pharmacokinetics, safety and inducible cytokine responses during a phase 1 trial of the oral histone deacetylase inhibitor ITF2357 (givinostat). Mol Med 2011; 17: 353-62.
-
(2011)
Mol Med
, vol.17
, pp. 353-362
-
-
Furlan, A.1
Monzani, V.2
Reznikov, L.L.3
|