Modeling the drugs' passive transfer in the body based on their chromatographic behavior

Journal of Pharmaceutical and Biomedical Analysis

Volumn 100, Issue , 2014, Pages 94-102

  Kouskoura, Maria G ^a   Kachrimanis, Kyriakos G ^a   Markopoulou, Catherine K ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

ANNs; Butyl column; Drug likeness; PLS; RP HPLC

Indexed keywords

1 NAPHTHOL; 1,2 DICHLOROBENZENE; 1,2,4 TRICHLOROBENZENE; 1,3 DICHLOROBENZENE; 1,3 DINITROBENZENE; 1,4 DICHLOROBENZENE; 2 NAPHTHOL; 2 NITROPHENOL; 4 NITROANILINE; 4 NITROPHENOL; ANILINE; ANISOLE; BENZALDEHYDE; BENZENE; BENZOIC ACID; BENZONITRILE; BENZYL CHLORIDE; BROMOBENZENE; CHLOROBENZENE; NAPHTHALENE; NITROBENZENE; ORTHO XYLENE; PHENELZINE; PHENOL; PHENYLACETIC ACID; PHENYLPROPANOLAMINE; SALICYLAMIDE; TOLUENE; UNINDEXED DRUG; XYLENE; DRUG;

ADSORPTION; ALGORITHM; ARTICLE; ARTIFICIAL NEURAL NETWORK; BLOOD BRAIN BARRIER; CELL MEMBRANE; DRUG ABSORPTION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INTESTINE ABSORPTION; LIPOPHILICITY; PARTIAL LEAST SQUARES REGRESSION; PHYSICAL CHEMISTRY; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; BIOLOGICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER PROGRAM; COMPUTER SIMULATION; PHARMACOKINETICS; REGRESSION ANALYSIS; REVERSED PHASE LIQUID CHROMATOGRAPHY; STRUCTURE ACTIVITY RELATION; DRUG ANALYSIS; GENOMICS; MOLECULAR WEIGHT; PERSONALIZED MEDICINE; SIMULATION;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, REVERSE-PHASE; COMPUTER SIMULATION; HUMANS; LEAST-SQUARES ANALYSIS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NEURAL NETWORKS (COMPUTER); PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; SOFTWARE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84906234831     PISSN: 07317085     EISSN: 1873264X     Source Type: Journal    
DOI: 10.1016/j.jpba.2014.07.031     Document Type: Article

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