Split liver transplantation using Hemiliver graft in the MELD era: A single center experience in the United States

American Journal of Transplantation

Volumn 14, Issue 9, 2014, Pages 2072-2080

  Hashimoto, K ^a   Quintini, C ^a   Aucejo, F N ^a   Fujiki, M ^a   Diago, T ^a   Watson, M J ^a   Kelly, D M ^a   Winans, C G ^a   Eghtesad, B ^a   Fung, J J ^a   Miller, C M ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Clinical research practice; extended criteria, organ allocation; liver transplantation; liver transplantation hepatology; split, donors and donation

Indexed keywords

ALANINE AMINOTRANSFERASE; BILIRUBIN; CREATININE; SODIUM;

ADOLESCENT; ADULT; AGED; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ARTICLE; BILE LEAKAGE; BILIRUBIN BLOOD LEVEL; BODY WEIGHT; CHILD; COLD ISCHEMIA; COMPARATIVE STUDY; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DISSECTOR; DONOR; FEMALE; GRAFT FAILURE; GRAFT RECIPIENT; GRAFT SURVIVAL; HEMILIVER GRAFT; HEPATIC ARTERY THROMBOSIS; HEPATOPULMONARY SYNDROME; HUMAN; LENGTH OF STAY; LIVER CELL CARCINOMA; LIVER GRAFT; LIVER TRANSPLANTATION; LIVER WEIGHT; MAJOR CLINICAL STUDY; MALE; METABOLIC DISORDER; MODEL FOR END STAGE LIVER DISEASE SCORE; PORTAL HYPERTENSION; PORTAL VEIN THROMBOSIS; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; RETRANSPLANTATION; RETROSPECTIVE STUDY; SODIUM BLOOD LEVEL; THROMBOCYTE COUNT; UNITED STATES; VIRUS HEPATITIS; END STAGE LIVER DISEASE; PROCEDURES; YOUNG ADULT;

ADOLESCENT; ADULT; CHILD; END STAGE LIVER DISEASE; FEMALE; HUMANS; LIVER TRANSPLANTATION; MALE; RETROSPECTIVE STUDIES; UNITED STATES; YOUNG ADULT;

EID: 84906217228     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/ajt.12791     Document Type: Article

References (44)

1. Pichlmayr R, Ringe B, Gubernatis G, Hauss J, Bunzendahl H,. Transplantation of a donor liver to 2 recipients (splitting transplantation): A new method in the further development of segmental liver transplantation. Langenbecks Arch Chir 1988; 373: 127-130.
2. Bismuth H, Morino M, Castaing D, et al. Emergency orthotopic liver transplantation in two patients using one donor liver. Br J Surg 1989; 76: 722-724.
3. Emond JC, Whitington PF, Thistlethwaite JR, et al. Transplantation of two patients with one liver. Analysis of a preliminary experience with 'split-liver' grafting. Ann Surg 1990; 212: 14-22.
4. Azoulay D, Astarcioglu I, Bismuth H, et al. Split-liver transplantation. The Paul Brousse policy. Ann Surg 1996; 224: 737-746.
5. Azoulay D, Castaing D, Adam R, et al. Split-liver transplantation for two adult recipients: Feasibility and long-term outcomes. Ann Surg 2001; 233: 565-574.
6. Humar A, Ramcharan T, Sielaff TD, et al. Split liver transplantation for two adult recipients: An initial experience. Am J Transplant 2001; 1: 366-372.
7. Kilic M, Seu P, Stribling RJ, Ghalib R, Goss JA,. In situ splitting of the cadaveric liver for two adult recipients. Transplantation 2001; 72: 1853-1858.
8. Zamir G, Olthoff KM, Desai N, Markmann JF, Shaked A,. Toward further expansion of the organ pool for adult liver recipients: Splitting the cadaveric liver into right and left lobes. Transplantation 2002; 74: 1757-1761.
9. Broering DC, Topp S, Schaefer U, et al. Split liver transplantation and risk to the adult recipient: Analysis using matched pairs. J Am Coll Surg 2002; 195: 648-657.
10. Yersiz H, Renz JF, Farmer DG, Hisatake GM, McDiarmid SV, Busuttil RW,. One hundred in situ split-liver transplantations: A single-center experience. Ann Surg 2003; 238: 496-505.
11. Renz JF, Emond JC, Yersiz H, Ascher NL, Busuttil RW,. Split-liver transplantation in the United States: Outcomes of a national survey. Ann Surg 2004; 239: 172-181.
12. Merion RM, Rush SH, Dykstra DM, Goodrich N, Freeman RB Jr, Wolfe RA,. Predicted lifetimes for adult and pediatric split liver versus adult whole liver transplant recipients. Am J Transplant 2004; 4: 1792-1797.
13. Broering DC, Wilms C, Lenk C, et al. Technical refinements and results in full-right full-left splitting of the deceased donor liver. Ann Surg 2005; 242: 802-812.
14. Wilms C, Walter J, Kaptein M, et al. Long-term outcome of split liver transplantation using right extended grafts in adulthood: A matched pair analysis. Ann Surg 2006; 244: 865-872.
15. Adham M, Dumortier J, Abdelaal A, Sagnard P, Boucaud C, Boillot O,. Does middle hepatic vein omission in a right split graft affect the outcome of liver transplantation? A comparative study of right split livers with and without the middle hepatic vein. Liver Transpl 2007; 13: 829-837.
16. Giacomoni A, Lauterio A, Donadon M, et al. Should we still offer split-liver transplantation for two adult recipients? A retrospective study of our experience. Liver Transpl 2008; 14: 999-1006.
17. Nadalin S, Schaffer R, Fruehauf N,. Split-liver transplantation in the high-MELD adult patient: Are we being too cautious ? Transpl Int 2009; 22: 702-706.
18. Cescon M, Grazi GL, Ravaioli M, et al. Conventional split liver transplantation for two adult recipients: A recent experience in a single European center. Transplantation 2009; 88: 1117-1122.
19. Viganò L, Laurent A, Tayar C, et al. Outcomes in adult recipients of right-sided liver grafts in split-liver procedures. HPB (Oxford) 2010; 12: 195-203.
20. Vagefi PA, Parekh J, Ascher NL, Roberts JP, Freise CE,. Outcomes with split liver transplantation in 106 recipients: The University of California San Francisco experience from 1993 to 2010. Arch Surg 2011; 146: 1052-1059.
21. Zambelli M, Andorno E, De Carlis L, et al. Full-right-full-left split liver transplantation: The retrospective analysis of an early multicenter experience including graft sharing. Am J Transplant 2012; 12: 2198-2210.
22. Lee WC, Chan KM, Chou HS, et al. Feasibility of split liver transplantation for 2 adults in the model of end-stage liver disease era. Ann Surg 2012; 258: 306-311.
23. Emre S, Umman V,. Split liver transplantation: An overview. Transplant Proc 2011; 43: 884-887.
24. Feng S, Goodrich NP, Bragg-Gresham JL, et al. Characteristics associated with liver graft failure: The concept of a donor risk index. Am J Transplant 2006; 6: 783-790.
25. Burroughs AK, Sabin CA, Rolles K, et al. 3-month and 12-month mortality after first liver transplant in adults in Europe: Predictive models for outcome. Lancet 2006; 367: 225-232.
26. Boillot O, Delafosse B, Méchet I, Boucaud C, Pouyet M,. Small-for-size partial liver graft in an adult recipient; a new transplant technique. Lancet 2002; 359: 406-407.
27. Hashimoto K, Aucejo F, Quintini C, et al. Liver transplantation at Cleveland Clinic. Clin Transpl 2010; 195-206.
28. Soejima Y, Shimada M, Suehiro T, et al. Outcome analysis in adult-to-adult living donor liver transplantation using the left lobe. Liver Transpl 2003; 9: 581-586.
29. Lee SG,. Living-donor liver transplantation in adults. Br Med Bull 2010; 94: 33-48.
30. Aucejo FN, Hashimoto K, Quintini C, et al. Triple-phase computed tomography and intraoperative flow measurements improve the management of portosystemic shunts during liver transplantation. Liver Transpl 2008; 14: 96-99.
31. Hashimoto K, Fung J,. In situ liver splitting. In:, Oniscu G, Forsythe J, Fung J, eds. Abdominal organ retrieval and transplantation bench surgery. Oxford: Wiley-Blackwell, 2013, pp. 101-115.
32. Liddo G, Buc E, Nagarajan G, Hidaka M, Dokmak S, Belghiti J,. The liver hanging manoeuvre. HPB 2009; 11: 296-305.
33. Hashimoto K, Miller C,. The use of marginal grafts in liver transplantation. J Hepatobiliary Pancreat Surg 2008; 15: 92-101.
34. Hill MJ, Hughes M, Jie T, et al. Graft weight/recipient weight ratio: How well does it predict outcome after partial liver transplants ? Liver Transpl 2009; 15: 1056-1062.
35. Selzner M, Kashfi A, Cattral MS, et al. A graft to body weight ratio less than 0.8 does not exclude adult-to-adult right-lobe living donor liver transplantation. Liver Transpl 2009; 15: 1776-1782.
36. Moon JI, Kwon CH, Joh JW, et al. Safety of small-for-size grafts in adult-to-adult living donor liver transplantation using the right lobe. Liver Transpl 2010; 16: 864-869.
37. Pratschke J, Wilhelm MJ, Kusaka M, et al. Brain death and its influence on donor organ quality and outcome after transplantation. Transplantation 1999; 67: 343-348.
38. Uchiyama H, Harada N, Sanefuji K, et al. Dual hepatic artery reconstruction in living donor liver transplantation using a left hepatic graft with 2 hepatic arterial stumps. Surgery 2010; 147: 878-886.
39. Florman S, Miller CM,. Live donor liver transplantation. Liver Transpl 2006; 12: 499-510.
40. Thuluvath PJ, Guidinger MK, Fung JJ, Johnson LB, Rayhill SC, Pelletier SJ,. Liver transplantation in the United States, 1999-2008. Am J Transplant 2010; 10: 1003-1019.
41. Vulchev A, Roberts JP, Stock PG,. Ethical issues in split versus whole liver transplantation. Am J Transplant 2004; 4: 1737-1740.
42. Collett D, O'Neill J, Neuberger J,. Splitting livers-Balancing the gain and the pain. Transpl Int 2008; 21: 218-222.
43. Liu CL, Fan ST, Lo CM, et al. Operative outcomes of adult-to-adult right lobe live donor liver transplantation: A comparative study with cadaveric whole-graft liver transplantation in a single center. Ann Surg 2006; 243: 404-410.
44. Freise CE, Gillespie BW, Koffron AJ, et al. Recipient morbidity after living and deceased donor liver transplantation: Findings from the A2ALL Retrospective Cohort Study. Am J Transplant 2008; 8: 2569-2579.