Bone marrow mesenchymal stem cells ameliorate colitis-Associated tumorigenesis in mice

Biochemical and Biophysical Research Communications

Volumn 450, Issue 4, 2014, Pages 1402-1408

  Chen, Zexian ^a   He, Xiaowen ^a   He, Xiaosheng ^a   Chen, Xiuting ^a   Lin, Xutao ^a   Zou, Yifeng ^a   Wu, Xiaojian ^a   Lan, Ping ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Colitis; Inflammatory bowel disease; Mesenchymal stem cells; Mice; Tumorigenesis

Indexed keywords

COLITIS; INFLAMMATORY BOWEL DISEASE; MESENCHYMAL STEM CELLS; MICE; TUMORIGENESIS;

ANIMALS; BLOTTING, WESTERN; BONE MARROW CELLS; CELLS, CULTURED; COLITIS; COLORECTAL NEOPLASMS; CYTOKINES; FEMALE; FLOW CYTOMETRY; INFLAMMATION MEDIATORS; MESENCHYMAL STROMAL CELLS; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; REAL-TIME POLYMERASE CHAIN REACTION; STAT3 TRANSCRIPTION FACTOR; STEM CELL TRANSPLANTATION;

EID: 84906098372     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2014.07.002     Document Type: Article

References (34)

1. B. Khor, A. Gardet, and R.J. Xavier Genetics and pathogenesis of inflammatory bowel disease Nature 474 2011 307 317
2. S.I. Grivennikov, F.R. Greten, and M. Karin Immunity, inflammation, and cancer Cell 140 2010 883 899
3. F.A. Fitzpatrick Inflammation, carcinogenesis and cancer Int. Immunopharmacol. 1 2001 1651 1667
4. S.H. Itzkowitz, and X. Yio Inflammation and cancer IV. Colorectal cancer in inflammatory bowel disease: the role of inflammation Am. J. Physiol. Gastrointest. Liver Physiol. 287 2004 G7 G17
5. J.A. Eaden, K.R. Abrams, and J.F. Mayberry The risk of colorectal cancer in ulcerative colitis: a meta-Analysis Gut 48 2001 526 535
6. T. Jess, M. Gamborg, P. Matzen, P. Munkholm, and T.I. Sorensen Increased risk of intestinal cancer in Crohn's disease: a meta-Analysis of population-based cohort studies Am. J. Gastroenterol. 100 2005 2724 2729
7. D. Baksh, L. Song, and R.S. Tuan Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy J. Cell Mol. Med. 8 2004 301 316
8. C.M. Kolf, E. Cho, and R.S. Tuan Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation Arthritis Res. Ther. 9 2007 204
9. A.J. Nauta, and W.E. Fibbe Immunomodulatory properties of mesenchymal stromal cells Blood 110 2007 3499 3506
10. S. Zhao, R. Wehner, M. Bornhauser, R. Wassmuth, M. Bachmann, and M. Schmitz Immunomodulatory properties of mesenchymal stromal cells and their therapeutic consequences for immune-mediated disorders Stem Cells Dev. 19 2010 607 614
11. A.I. Caplan Adult mesenchymal stem cells for tissue engineering versus regenerative medicine J. Cell Physiol. 213 2007 341 347
12. M.E. Bernardo, and W.E. Fibbe Safety and efficacy of mesenchymal stromal cell therapy in autoimmune disorders Ann. N. Y. Acad. Sci. 1266 2012 107 117
13. J. Tan, W. Wu, X. Xu, L. Liao, F. Zheng, S. Messinger, X. Sun, J. Chen, S. Yang, J. Cai, X. Gao, A. Pileggi, and C. Ricordi Induction therapy with autologous mesenchymal stem cells in living-related kidney transplants: a randomized controlled trial JAMA 307 2012 1169 1177
14. K.L. Wong, K.B. Lee, B.C. Tai, P. Law, E.H. Lee, and J.H. Hui Injectable cultured bone marrow-derived mesenchymal stem cells in varus knees with cartilage defects undergoing high tibial osteotomy: a prospective, randomized controlled clinical trial with 2 years' follow-up Arthroscopy 29 2013 2020 2028
15. X.W. He, X.S. He, L. Lian, X.J. Wu, and P. Lan Systemic infusion of bone marrow-derived mesenchymal stem cells for treatment of experimental colitis in mice Dig. Dis. Sci. 57 2012 3136 3144
16. L. Qiao, Z. Xu, T. Zhao, Z. Zhao, M. Shi, R.C. Zhao, L. Ye, and X. Zhang Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model Cell Res. 18 2008 500 507
17. L. Li, H. Tian, Z. Chen, W. Yue, S. Li, and W. Li Inhibition of lung cancer cell proliferation mediated by human mesenchymal stem cells Acta Biochim. Biophys. Sin. (Shanghai) 43 2011 143 148
18. I.A. Ho, H.C. Toh, W.H. Ng, Y.L. Teo, C.M. Guo, K.M. Hui, and P.Y. Lam Human bone marrow-derived mesenchymal stem cells suppress human glioma growth through inhibition of angiogenesis Stem Cells 31 2013 146 155
19. T. Zhang, Y.W. Lee, Y.F. Rui, T.Y. Cheng, X.H. Jiang, and G. Li Bone marrow-derived mesenchymal stem cells promote growth and angiogenesis of breast and prostate tumors Stem Cell Res. Ther. 4 2013 70
20. Y. Liu, Z.P. Han, S.S. Zhang, Y.Y. Jing, X.X. Bu, C.Y. Wang, K. Sun, G.C. Jiang, X. Zhao, R. Li, L. Gao, Q.D. Zhao, M.C. Wu, and L.X. Wei Effects of inflammatory factors on mesenchymal stem cells and their role in the promotion of tumor angiogenesis in colon cancer J. Biol. Chem. 286 2011 25007 25015
21. M. Soleimani, and S. Nadri A protocol for isolation and culture of mesenchymal stem cells from mouse bone marrow Nat. Protoc. 4 2009 102 106
22. C. Neufert, C. Becker, and M.F. Neurath An inducible mouse model of colon carcinogenesis for the analysis of sporadic and inflammation-driven tumor progression Nat. Protoc. 2 2007 1998 2004
23. X. Yang, F. Zhang, Y. Wang, M. Cai, Q. Wang, Q. Guo, Z. Li, and R. Hu Oroxylin A inhibits colitis-Associated carcinogenesis through modulating the IL-6/STAT3 signaling pathway Inflamm. Bowel Dis. 19 2013 1990 2000
24. D. Garcia-Olmo, M. Garcia-Arranz, D. Herreros, I. Pascual, C. Peiro, and J.A. Rodriguez-Montes A phase I clinical trial of the treatment of Crohn's fistula by adipose mesenchymal stem cell transplantation Dis. Colon Rectum 48 2005 1416 1423
25. D. Garcia-Olmo, D. Herreros, I. Pascual, J.A. Pascual, E. Del-Valle, J. Zorrilla, P. De-La-Quintana, M. Garcia-Arranz, and M. Pascual Expanded adipose-derived stem cells for the treatment of complex perianal fistula: a phase II clinical trial Dis. Colon Rectum 52 2009 79 86
26. F. de la Portilla, F. Alba, D. Garcia-Olmo, J.M. Herrerias, F.X. Gonzalez, and A. Galindo Expanded allogeneic adipose-derived stem cells (eASCs) for the treatment of complex perianal fistula in Crohn's disease: results from a multicenter phase I/IIa clinical trial Int. J. Colorectal Dis. 28 2013 313 323
27. G.M. Forbes, M.J. Sturm, R.W. Leong, M.P. Sparrow, D. Segarajasingam, A.G. Cummins, M. Phillips, and R.P. Herrmann A Phase 2 Study of Allogeneic Mesenchymal Stromal Cells for Luminal Crohn's Disease Refractory to Biologic Therapy Clin. Gastroenterol. Hepatol. 12 2014 64 71
28. M. Keramidas, F. de Fraipont, A. Karageorgis, A. Moisan, V. Persoons, M.J. Richard, J.L. Coll, and C. Rome The dual effect of mscs on tumour growth and tumour angiogenesis Stem Cell Res. Ther. 4 2013 41
29. C. Becker, M.C. Fantini, S. Wirtz, A. Nikolaev, R. Kiesslich, H.A. Lehr, P.R. Galle, and M.F. Neurath In vivo imaging of colitis and colon cancer development in mice using high resolution chromoendoscopy Gut 54 2005 950 954
30. J.K. Kundu, and Y.J. Surh Inflammation: gearing the journey to cancer Mutat. Res. 659 2008 15 30
31. S.A. Azer Overview of molecular pathways in inflammatory bowel disease associated with colorectal cancer development Eur. J. Gastroenterol. Hepatol. 25 2013 271 281
32. J. Bollrath, T.J. Phesse, V.A. von Burstin, T. Putoczki, M. Bennecke, T. Bateman, T. Nebelsiek, T. Lundgren-May, O. Canli, S. Schwitalla, V. Matthews, R.M. Schmid, T. Kirchner, M.C. Arkan, M. Ernst, and F.R. Greten Gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-Associated tumorigenesis Cancer Cell 15 2009 91 102
33. S. Grivennikov, E. Karin, J. Terzic, D. Mucida, G.Y. Yu, S. Vallabhapurapu, J. Scheller, S. Rose-John, H. Cheroutre, L. Eckmann, and M. Karin IL-6 and Stat3 are required for survival of intestinal epithelial cells and development of colitis-Associated cancer Cancer Cell 15 2009 103 113
34. Z.S.K. Al, and J. Turkson STAT3 as a target for inducing apoptosis in solid and hematological tumors Cell Res. 18 2008 254 267