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Volumn 58, Issue 9, 2014, Pages 5581-5584

Micafungin at physiological serum concentrations shows antifungal activity against Candida albicans and Candida parapsilosis biofilms

Author keywords

[No Author keywords available]

Indexed keywords

MICAFUNGIN; ANTIFUNGAL AGENT; ECHINOCANDIN; LIPOPEPTIDE;

EID: 84906096674     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.02738-14     Document Type: Article
Times cited : (16)

References (43)
  • 1
    • 0032787411 scopus 로고    scopus 로고
    • National Nosocomial Infections Surveillance (NNIS) System report, data summary from January 1990-May 1999, issued June 1999
    • NNIS System
    • NNIS System 1999. National Nosocomial Infections Surveillance (NNIS) System report, data summary from January 1990-May 1999, issued June 1999. Am. J. Infect. Control 27:520-532. http://dx.doi.org/10.1016/S0196-6553(99)70031-3.
    • (1999) Am. J. Infect. Control , vol.27 , pp. 520-532
  • 2
    • 0026062881 scopus 로고
    • Major trends in the microbial etiology of nosocomial infection
    • Schaberg DR, Culver DH, Gaynes RP. 1991. Major trends in the microbial etiology of nosocomial infection. Am. J. Med. 91(Suppl 2):S72-S75. http://dx.doi.org/10.1016/0002-9343(91)90346-Y.
    • (1991) Am. J. Med. , vol.91 , Issue.SUPPL. 2
    • Schaberg, D.R.1    Culver, D.H.2    Gaynes, R.P.3
  • 3
    • 17144466471 scopus 로고
    • Secular trends in nosocomial primary bloodstream infections in the United States, 1980-1989. National Nosocomial Infections Surveillance System
    • Banerjee SN, Emori TG, Culver DH, Gaynes RP, Jarvis WR, Horan T, Edwards JR, Tolson J, Hernderson T, Martone WJ. 1991. Secular trends in nosocomial primary bloodstream infections in the United States, 1980-1989. National Nosocomial Infections Surveillance System. Am. J. Med. 91(Suppl 2):S86 -S89. http://dx.doi.org/10.1016/0002-9343(91)90349-3.
    • (1991) Am. J. Med. , vol.91 , Issue.SUPPL. 2
    • Banerjee, S.N.1    Emori, T.G.2    Culver, D.H.3    Gaynes, R.P.4    Jarvis, W.R.5    Horan, T.6    Edwards, J.R.7    Tolson, J.8    Hernderson, T.9    Martone, W.J.10
  • 4
    • 0031899916 scopus 로고    scopus 로고
    • National surveillance of nosocomial blood stream infection due to Candida albicans: Frequency of occurrence and antifungal susceptibility in the SCOPE program
    • DOI 10.1016/S0732-8893(97)00240-X, PII S073288939700240X
    • Pfaller MA, Jones RN, Messer SA, Edmond MB, Wenzel RP. 1998. National surveillance of nosocomial blood stream infection due to Candida albicans: frequency of occurrence and antifungal susceptibility in the SCOPE Program. Diagn. Microbiol. Infect. Dis. 31:327-332. http://dx.doi.org/10.1016/S0732- 8893(97)00240-X. (Pubitemid 28212061)
    • (1998) Diagnostic Microbiology and Infectious Disease , vol.31 , Issue.1 , pp. 327-332
    • Pfaller, M.A.1    Jones, R.N.2    Messer, S.A.3    Edmond, M.B.4    Wenzel, R.P.5
  • 5
    • 0031939508 scopus 로고    scopus 로고
    • National surveillance of nosocomial blood stream infection due to species of Candida other than Candida albicans: Frequency of occurrence and antifungal susceptibility in the SCOPE program
    • DOI 10.1016/S0732-8893(97)00192-2, PII S0732889397001922
    • Pfaller MA, Jones RN, Messer SA, Edmond MB, Wenzel RP. 1998. National surveillance of nosocomial blood stream infection due to species of Candida other than Candida albicans: frequency of occurrence and antifungal susceptibility in the SCOPE Program. SCOPE Participant Group. Surveillance and Control of Pathogens of Epidemiologic. Diagn. Microbiol. Infect. Dis. 30:121-129. (Pubitemid 28102867)
    • (1998) Diagnostic Microbiology and Infectious Disease , vol.30 , Issue.2 , pp. 121-129
    • Pfaller, M.A.1    Jones, R.N.2    Messer, S.A.3    Edmond, M.B.4    Wenzel, R.P.5
  • 6
    • 0036841544 scopus 로고    scopus 로고
    • Secular trends of candidemia over 12 years in adult patients at a tertiary care hospital
    • DOI 10.1097/00005792-200211000-00003
    • Garbino J, Kolarova L, Rohner P, Lew D, Pichna P, Pittet D. 2002. Secular trends of candidemia over 12 years in adult patients at a tertiary care hospital. Medicine 81:425-433. http://dx.doi.org/10.1097/00005792-200211000- 00003. (Pubitemid 35285962)
    • (2002) Medicine , vol.81 , Issue.6 , pp. 425-433
    • Garbino, J.1    Kolarova, L.2    Rohner, P.3    Lew, D.4    Pichna, P.5    Pittet, D.6
  • 7
    • 84882613183 scopus 로고    scopus 로고
    • Evolution and aetiological shift of catheterrelated bloodstream infection in a whole institution: The microbiology department may act as a watchtower
    • Rodriguez-Creixems M, Munoz P, Martin-Rabadan P, Cercenado E, Guembe M, Bouza E. 2013. Evolution and aetiological shift of catheterrelated bloodstream infection in a whole institution: the microbiology department may act as a watchtower. Clin. Microbiol. Infect. 19:845-851. http://dx.doi.org/10.1111/1469- 0691.12050.
    • (2013) Clin. Microbiol. Infect. , vol.19 , pp. 845-851
    • Rodriguez-Creixems, M.1    Munoz, P.2    Martin-Rabadan, P.3    Cercenado, E.4    Guembe, M.5    Bouza, E.6
  • 8
    • 49149096183 scopus 로고    scopus 로고
    • Bloodstream infections: Evolution and trends in the microbiology workload, incidence, and etiology, 1985-2006
    • Rodriguez-Creixems M, Alcala L, Munoz P, Cercenado E, Vicente T, Bouza E. 2008. Bloodstream infections: evolution and trends in the microbiology workload, incidence, and etiology, 1985-2006. Medicine 87: 234-249. http://dx.doi.org/10.1097/MD.0b013e318182119b.
    • (2008) Medicine , vol.87 , pp. 234-249
    • Rodriguez-Creixems, M.1    Alcala, L.2    Munoz, P.3    Cercenado, E.4    Vicente, T.5    Bouza, E.6
  • 9
    • 0027172842 scopus 로고
    • Pathogenesis of infections related to intravascular catheterization
    • Goldmann DA, Pier GB. 1993. Pathogenesis of infections related to intravascular catheterization. Clin. Microbiol. Rev. 6:176-192.
    • (1993) Clin. Microbiol. Rev. , vol.6 , pp. 176-192
    • Goldmann, D.A.1    Pier, G.B.2
  • 11
    • 0024239135 scopus 로고
    • Hospital-acquired candidemia. The attributable mortality and excess length of stay
    • DOI 10.1001/archinte.148.12.2642
    • Wey SB, Mori M, Pfaller MA, Woolson RF, Wenzel RP. 1988. Hospital-acquired candidemia. The attributable mortality and excess length of stay. Arch. Intern. Med. 148:2642-2645. (Pubitemid 19048184)
    • (1988) Archives of Internal Medicine , vol.148 , Issue.12 , pp. 2642-2645
    • Wey, S.B.1    Mori, M.2    Pfaller, M.A.3    Woolson, R.F.4    Wenzel, R.P.5
  • 12
    • 18044375585 scopus 로고    scopus 로고
    • Candida biofilms: An update
    • DOI 10.1128/EC.4.4.633-638.2005
    • Ramage G, Saville SP, Thomas DP, Lopez-Ribot JL. 2005. Candida biofilms: an update. Eukaryot. Cell 4:633-638. http://dx.doi.org/10.1128/EC.4.4.633-638. 2005. (Pubitemid 40600417)
    • (2005) Eukaryotic Cell , vol.4 , Issue.4 , pp. 633-638
    • Ramage, G.1    Saville, S.P.2    Thomas, D.P.3    Lopez-Ribot, J.L.4
  • 13
    • 33746300488 scopus 로고    scopus 로고
    • Candida albicans biofilm development, modeling a host-pathogen interaction
    • DOI 10.1016/j.mib.2006.06.007, PII S1369527406000907
    • Nett J, Andes D. 2006. Candida albicans biofilm development, modeling a host-pathogen interaction. Curr. Opin. Microbiol. 9:340-345. http://dx.doi.org/10.1016/j.mib.2006.06.007. (Pubitemid 44108718)
    • (2006) Current Opinion in Microbiology , vol.9 , Issue.4 , pp. 340-345
    • Nett, J.1    Andes, D.2
  • 14
    • 31344456165 scopus 로고    scopus 로고
    • Biofilm production by clinical isolates of Candida species
    • DOI 10.1080/13693780500338084, PII X7073182173770
    • Kumar CP, Menon T. 2006. Biofilm production by clinical isolates of Candida species. Med. Mycol. 44:99-101. http://dx.doi.org/10.1080/ 13693780500338084. (Pubitemid 43135563)
    • (2006) Medical Mycology , vol.44 , Issue.1 , pp. 99-101
    • Girish, K.C.P.1    Menon, T.2
  • 15
    • 79251498606 scopus 로고    scopus 로고
    • An easy and economical in vitro method for the formation of Candida albicans biofilms under continuous conditions of flow
    • Uppuluri P, Lopez-Ribot JL. 2010. An easy and economical in vitro method for the formation of Candida albicans biofilms under continuous conditions of flow. Virulence 1:483-487. http://dx.doi.org/10.4161/viru.1.6.13186.
    • (2010) Virulence , vol.1 , pp. 483-487
    • Uppuluri, P.1    Lopez-Ribot, J.L.2
  • 16
    • 80052590913 scopus 로고    scopus 로고
    • Candida tropicalis biofilms: Artificial urine, urinary catheters and flow model
    • Negri M, Silva SN, Henriques M, Azeredo J, Svidzinski T, Oliveira RR. 2011. Candida tropicalis biofilms: artificial urine, urinary catheters and flow model. Med. Mycol. 49:739-747. http://dx.doi.org/10.3109/13693786.2011.560619.
    • (2011) Med. Mycol. , vol.49 , pp. 739-747
    • Negri, M.1    Silva, S.N.2    Henriques, M.3    Azeredo, J.4    Svidzinski, T.5    Oliveira, R.R.6
  • 17
    • 70349990092 scopus 로고    scopus 로고
    • Biofilms of non-Candida albicans Candida species: Quantification, structure and matrix composition
    • Silva S, Henriques M, Martins A, Oliveira R, Williams D, Azeredo J. 2009. Biofilms of non-Candida albicans Candida species: quantification, structure and matrix composition. Med. Mycol. 47:681-689. http://dx.doi.org/10.3109/ 13693780802549594.
    • (2009) Med. Mycol. , vol.47 , pp. 681-689
    • Silva, S.1    Henriques, M.2    Martins, A.3    Oliveira, R.4    Williams, D.5    Azeredo, J.6
  • 19
    • 58149196359 scopus 로고    scopus 로고
    • Amphotericin B lipid complex is efficacious in the treatment of Candida albicans biofilms using a model of catheter-associated Candida biofilms
    • Mukherjee PK, Long L, Kim HG, Ghannoum MA. 2009. Amphotericin B lipid complex is efficacious in the treatment of Candida albicans biofilms using a model of catheter-associated Candida biofilms. Int. J. Antimicrob. Agents. 33:149-153. http://dx.doi.org/10.1016/j.ijantimicag.2008.07.030.
    • (2009) Int. J. Antimicrob. Agents. , vol.33 , pp. 149-153
    • Mukherjee, P.K.1    Long, L.2    Kim, H.G.3    Ghannoum, M.A.4
  • 20
    • 77957357014 scopus 로고    scopus 로고
    • In vivo efficacy of anidulafungin against mature Candida albicans biofilms in a novel rat model of catheter-associated Candidiasis
    • Kucharikova S, Tournu H, Holtappels M, Van Dijck P, Lagrou K. 2010. In vivo efficacy of anidulafungin against mature Candida albicans biofilms in a novel rat model of catheter-associated Candidiasis. Antimicrob. Agents Chemother. 54:4474-4475. http://dx.doi.org/10.1128/AAC.00697-10.
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 4474-4475
    • Kucharikova, S.1    Tournu, H.2    Holtappels, M.3    Van Dijck, P.4    Lagrou, K.5
  • 21
    • 69049092799 scopus 로고    scopus 로고
    • Treatment and prevention of Candida albicans biofilms with caspofungin in a novel central venous catheter murine model of candidiasis
    • Lazzell AL, Chaturvedi AK, Pierce CG, Prasad D, Uppuluri P, Lopez-Ribot JL. 2009. Treatment and prevention of Candida albicans biofilms with caspofungin in a novel central venous catheter murine model of candidiasis. J. Antimicrob. Chemother. 64:567-570. http://dx.doi.org/10.1093/jac/dkp242.
    • (2009) J. Antimicrob. Chemother. , vol.64 , pp. 567-570
    • Lazzell, A.L.1    Chaturvedi, A.K.2    Pierce, C.G.3    Prasad, D.4    Uppuluri, P.5    Lopez-Ribot, J.L.6
  • 23
    • 4344670178 scopus 로고    scopus 로고
    • Penetration of Candida biofilms by antifungal agents
    • DOI 10.1128/AAC.48.9.3291-3297.2004
    • Al-Fattani MA, Douglas LJ. 2004. Penetration of Candida biofilms by antifungal agents. Antimicrob. Agents Chemother. 48:3291-3297. http://dx.doi.org/10.1128/AAC.48.9.3291-3297.2004. (Pubitemid 39129321)
    • (2004) Antimicrobial Agents and Chemotherapy , vol.48 , Issue.9 , pp. 3291-3297
    • Al-Fattani, M.A.1    Douglas, L.J.2
  • 25
  • 26
    • 70349318567 scopus 로고    scopus 로고
    • Biofilm formation and effect of caspofungin on biofilm structure of Candida species bloodstream isolates
    • Ferreira JA, Carr JH, Starling CE, de Resende MA, Donlan RM. 2009. Biofilm formation and effect of caspofungin on biofilm structure of Candida species bloodstream isolates. Antimicrob. Agents Chemother. 53: 4377-4384. http://dx.doi.org/10.1128/AAC.00316-09.
    • (2009) Antimicrob. Agents Chemother. , vol.53 , pp. 4377-4384
    • Ferreira, J.A.1    Carr, J.H.2    Starling, C.E.3    De Resende, M.A.4    Donlan, R.M.5
  • 27
    • 77950258189 scopus 로고    scopus 로고
    • In vitro activity of antifungal combinations against Candida albicans biofilms
    • Tobudic S, Kratzer C, Lassnigg A, Graninger W, Presterl E. 2010. In vitro activity of antifungal combinations against Candida albicans biofilms. J. Antimicrob. Chemother. 65:271-274. http://dx.doi.org/10.1093/jac/dkp429.
    • (2010) J. Antimicrob. Chemother. , vol.65 , pp. 271-274
    • Tobudic, S.1    Kratzer, C.2    Lassnigg, A.3    Graninger, W.4    Presterl, E.5
  • 28
    • 80054006415 scopus 로고    scopus 로고
    • Efficacy of anidulafungin against biofilms of different Candida species in long-term trials of continuous flow cultivation
    • Bernhardt H, Knoke M, Bernhardt J. 2011. Efficacy of anidulafungin against biofilms of different Candida species in long-term trials of continuous flow cultivation. Mycoses 54:e821-E827. http://dx.doi.org/10.1111/j.1439-0507. 2011.02036.x.
    • (2011) Mycoses , vol.54
    • Bernhardt, H.1    Knoke, M.2    Bernhardt, J.3
  • 29
    • 79959225684 scopus 로고    scopus 로고
    • Effects of fluconazole, amphotericin B, and caspofungin on Candida albicans biofilms under conditions of flow and on biofilm dispersion
    • Uppuluri P, Srinivasan A, Ramasubramanian A, Lopez-Ribot JL. 2011. Effects of fluconazole, amphotericin B, and caspofungin on Candida albicans biofilms under conditions of flow and on biofilm dispersion. Antimicrob. Agents Chemother. 55:3591-3593. http://dx.doi.org/10.1128/AAC.01701-10.
    • (2011) Antimicrob. Agents Chemother. , vol.55 , pp. 3591-3593
    • Uppuluri, P.1    Srinivasan, A.2    Ramasubramanian, A.3    Lopez-Ribot, J.L.4
  • 30
    • 45749112170 scopus 로고    scopus 로고
    • In vitro efficacies of caspofungin or micafungin catheter lock solutions on Candida albicans biofilm growth
    • DOI 10.1093/jac/dkn160
    • Cateau E, Rodier MH, Imbert C. 2008. In vitro efficacies of caspofungin or micafungin catheter lock solutions on Candida albicans biofilm growth. J. Antimicrob. Chemother. 62:153-155. http://dx.doi.org/10.1093/jac/dkn160. (Pubitemid 351865889)
    • (2008) Journal of Antimicrobial Chemotherapy , vol.62 , Issue.1 , pp. 153-155
    • Cateau, E.1    Rodier, M.-H.2    Imbert, C.3
  • 31
    • 33751182110 scopus 로고    scopus 로고
    • In vitro effects of micafungin against Candida biofilms on polystyrene and central venous catheter sections
    • DOI 10.1016/j.ijantimicag.2006.07.024, PII S0924857906003645
    • Seidler M, Salvenmoser S, Muller FM. 2006. In vitro effects of micafungin against Candida biofilms on polystyrene and central venous catheter sections. Int. J. Antimicrob. Agents. 28:568-573. http://dx.doi.org/10.1016/j.ijantimicag. 2006.07.024. (Pubitemid 44779180)
    • (2006) International Journal of Antimicrobial Agents , vol.28 , Issue.6 , pp. 568-573
    • Seidler, M.1    Salvenmoser, S.2    Muller, F.-M.C.3
  • 32
    • 79952814047 scopus 로고    scopus 로고
    • Possible role of azole and echinocandin lock solutions in the control of Candida biofilms associated with silicone
    • Cateau E, Berjeaud JM, Imbert C. 2011. Possible role of azole and echinocandin lock solutions in the control of Candida biofilms associated with silicone. Int. J. Antimicrob. Agents. 37:380-384. http://dx.doi.org/10.1016/j. ijantimicag.2010.12.016.
    • (2011) Int. J. Antimicrob. Agents. , vol.37 , pp. 380-384
    • Cateau, E.1    Berjeaud, J.M.2    Imbert, C.3
  • 33
    • 84877856149 scopus 로고    scopus 로고
    • Species-specific and drug-specific differences in susceptibility of Candida biofilms to echinocandins: Characterization of less common bloodstream isolates
    • Simitsopoulou M, Peshkova P, Tasina E, Katragkou A, Kyrpitzi D, Velegraki A, Walsh TJ, Roilides E. 2013. Species-specific and drug-specific differences in susceptibility of Candida biofilms to echinocandins: characterization of less common bloodstream isolates. Antimicrob. Agents Chemother. 57:2562-2570. http://dx.doi.org/10.1128/AAC.02541-12.
    • (2013) Antimicrob. Agents Chemother. , vol.57 , pp. 2562-2570
    • Simitsopoulou, M.1    Peshkova, P.2    Tasina, E.3    Katragkou, A.4    Kyrpitzi, D.5    Velegraki, A.6    Walsh, T.J.7    Roilides, E.8
  • 35
    • 80051504754 scopus 로고    scopus 로고
    • Microtiter dish biofilm formation assay
    • O'Toole GA. 2011. Microtiter dish biofilm formation assay. J. Vis Exp. 2011(47):489-495. http://dx.doi.org/10.3791/2437.
    • (2011) J. Vis Exp. , vol.2011 , Issue.47 , pp. 489-495
    • O'Toole, G.A.1
  • 37
    • 84862606187 scopus 로고    scopus 로고
    • EUCAST technical note on the EUCAST definitive document EDef 7.2: Method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts EDef 7.2 (EUCAST-AFST)
    • Arendrup MC, Cuenca-Estrella M, Lass-Florl C, Hope W. 2012. EUCAST technical note on the EUCAST definitive document EDef 7.2: method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts EDef 7.2 (EUCAST-AFST). Clin. Microbiol. Infect. 18:E246-E247. http://dx.doi.org/10.1111/j.1469-0691.2012.03880.x.
    • (2012) Clin. Microbiol. Infect. , vol.18
    • Arendrup, M.C.1    Cuenca-Estrella, M.2    Lass-Florl, C.3    Hope, W.4
  • 38
    • 0034863427 scopus 로고    scopus 로고
    • Standardized method for in vitro antifungal susceptibility testing of Candida albicans biofilms
    • DOI 10.1128/AAC.45.9.2475-2479.2001
    • Ramage G, Vande Walle K, Wickes BL, Lopez-Ribot JL. 2001. Standardized method for in vitro antifungal susceptibility testing of Candida albicans biofilms. Antimicrob. Agents Chemother. 45:2475-2479. http://dx.doi.org/10.1128/ AAC.45.9.2475-2479.2001. (Pubitemid 32801898)
    • (2001) Antimicrobial Agents and Chemotherapy , vol.45 , Issue.9 , pp. 2475-2479
    • Ramage, G.1    Vande, W.K.2    Wickes, B.L.3    Lopez-Ribot, J.L.4
  • 39
    • 51649130981 scopus 로고    scopus 로고
    • A simple and reproducible 96-well plate-based method for the formation of fungal biofilms and its application to antifungal susceptibility testing
    • Pierce CG, Uppuluri P, Tristan AR, Wormley FL, Jr, Mowat E, Ramage G, Lopez-Ribot JL. 2008. A simple and reproducible 96-well plate-based method for the formation of fungal biofilms and its application to antifungal susceptibility testing. Nat. Protoc. 3:1494-1500. http://dx.doi.org/10.1038/ nport.2008.141.
    • (2008) Nat. Protoc. , vol.3 , pp. 1494-1500
    • Pierce, C.G.1    Uppuluri, P.2    Tristan, A.R.3    Wormley Jr., F.L.4    Mowat, E.5    Ramage, G.6    Lopez-Ribot, J.L.7
  • 40
    • 77954694558 scopus 로고    scopus 로고
    • Early removal of central venous catheter in patients with candidemia does not improve outcome: Analysis of 842 patients from 2 randomized clinical trials
    • Nucci M, Anaissie E, Betts RF, Dupont BF, Wu C, Buell DN, Kovanda L, Lortholary O. 2010. Early removal of central venous catheter in patients with candidemia does not improve outcome: analysis of 842 patients from 2 randomized clinical trials. Clin. Infect. Dis. 51:295-303. http://dx.doi.org/10.1086/ 653935.
    • (2010) Clin. Infect. Dis. , vol.51 , pp. 295-303
    • Nucci, M.1    Anaissie, E.2    Betts, R.F.3    Dupont, B.F.4    Wu, C.5    Buell, D.N.6    Kovanda, L.7    Lortholary, O.8
  • 42
    • 67650732888 scopus 로고    scopus 로고
    • Pharmacodynamics and pharmacokinetics of micafungin in adults, children and neonate
    • In Spanish
    • Catalan-Gonzalez M, Carlos Montejo-Gonzalez J. 2009. Pharmacodynamics and pharmacokinetics of micafungin in adults, children and neonate. Rev. Iberoam Micol. 26:23-34. (In Spanish.) http://dx.doi.org/10.1016/S1130-1406(09)70005-1.
    • (2009) Rev. Iberoam Micol. , vol.26 , pp. 23-34
    • Catalan-Gonzalez, M.1    Carlos Montejo-Gonzalez, J.2
  • 43
    • 84906080906 scopus 로고    scopus 로고
    • Pharmacokinetics of FK463, a novel echinocandin analogue, in elderly and non-elderly subjects
    • abstr A-30. American Society for Microbiology, Washington, DC
    • Mukai T, Nakahara T, Uematsu T, Azuma J. 2001. Pharmacokinetics of FK463, a novel echinocandin analogue, in elderly and non-elderly subjects, abstr A-30. Abstr. 41st Intersci. Conf. Antimicrob. Agents Chemother. (ICAAC). American Society for Microbiology, Washington, DC.
    • (2001) Abstr. 41st Intersci. Conf. Antimicrob. Agents Chemother. (ICAAC)
    • Mukai, T.1    Nakahara, T.2    Uematsu, T.3    Azuma, J.4


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