-
1
-
-
84869215863
-
The role of transport mechanisms in mycobacterium tuberculosis drug resistance and tolerance
-
Sarathy JP, Dartois V, Lee EJ. 2012. The role of transport mechanisms in mycobacterium tuberculosis drug resistance and tolerance. Pharmaceuticals 5:1210-1235. http://dx.doi.org/10.3390/ph5111210.
-
(2012)
Pharmaceuticals
, vol.5
, pp. 1210-1235
-
-
Sarathy, J.P.1
Dartois, V.2
Lee, E.J.3
-
2
-
-
79958784137
-
Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: Classical and new drugs
-
Almeida Da Silva PE, Palomino JC. 2011. Molecular basis and mechanisms of drug resistance in Mycobacterium tuberculosis: classical and new drugs. J. Antimicrob. Chemother. 66:1417-1430. http://dx.doi.org/10.1093/jac/dkr173.
-
(2011)
J. Antimicrob. Chemother.
, vol.66
, pp. 1417-1430
-
-
Almeida Da Silva, P.E.1
Palomino, J.C.2
-
3
-
-
0030462751
-
Inhibition of the respiration of multi-drug resistant clinical isolates of Mycobacterium tuberculosis by thioridazine: Potential use for initial therapy of freshly diagnosed tuberculosis
-
DOI 10.1093/jac/38.6.1049
-
Amaral L, Kristiansen JE, Abebe LS, Millett W. 1996. Inhibition of the respiration of multidrug resistant clinical isolates of Mycobacterium tuberculosis by thioridazine: potential use for initial therapy of freshly diagnosed tuberculosis. J. Antimicrob. Chemother. 38:1049-1053. http://dx.doi.org/10.1093/jac/38.6.1049. (Pubitemid 27073284)
-
(1996)
Journal of Antimicrobial Chemotherapy
, vol.38
, Issue.6
, pp. 1049-1053
-
-
Amaral, L.1
Kristiansen, J.E.2
Abebe, L.S.3
Millett, W.4
-
4
-
-
67349140657
-
In vitro activity of thioridazine against mycobacteria
-
van Ingen J, van der Laan T, Amaral L, Dekhuijzen R, Boeree MJ, van Soolingen D. 2009. In vitro activity of thioridazine against mycobacteria. Int. J. Antimicrob. Agents 34:190-191. http://dx.doi.org/10.1016/j.ijantimicag.2009. 02.015.
-
(2009)
Int. J. Antimicrob. Agents
, vol.34
, pp. 190-191
-
-
Van Ingen, J.1
Van Der Laan, T.2
Amaral, L.3
Dekhuijzen, R.4
Boeree, M.J.5
Van Soolingen, D.6
-
5
-
-
0037416986
-
Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis
-
DOI 10.1128/AAC.47.3.917-922.2003
-
Ordway D, Viveiros M, Leandro C, Bettencourt R, Almeida J, Martins M, Kristiansen JE, Molnar J, Amaral L. 2003. Clinical concentrations of thioridazine kill intracellular multidrug-resistant Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 47:917-922. http://dx.doi.org/10.1128/AAC.47.3. 917-922.2003. (Pubitemid 36254216)
-
(2003)
Antimicrobial Agents and Chemotherapy
, vol.47
, Issue.3
, pp. 917-922
-
-
Ordway, D.1
Viveiros, M.2
Leandro, C.3
Bettencourt, R.4
Almeida, J.5
Martins, M.6
Kristiansen, J.E.7
Molnar, J.8
Amaral, L.9
-
6
-
-
35648948351
-
The curative activity of thioridazine on mice infected with Mycobacterium tuberculosis
-
Martins M, Viveiros M, Kristiansen JE, Molnar J, Amaral L. 2007. The curative activity of thioridazine on mice infected with Mycobacterium tuberculosis. In Vivo 21:771-775.
-
(2007)
In Vivo
, vol.21
, pp. 771-775
-
-
Martins, M.1
Viveiros, M.2
Kristiansen, J.E.3
Molnar, J.4
Amaral, L.5
-
7
-
-
77958612298
-
The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis
-
van Soolingen D, Hernandez-Pando R, Orozco H, Aguilar D, Magis-Escurra C, Amaral L, van Ingen J, Boeree MJ. 2010. The antipsychotic thioridazine shows promising therapeutic activity in a mouse model of multidrug-resistant tuberculosis. PLoS One 5:e12640. http://dx.doi.org/10.1371/journal.pone.0012640.
-
(2010)
PLoS One
, vol.5
-
-
Van Soolingen, D.1
Hernandez-Pando, R.2
Orozco, H.3
Aguilar, D.4
Magis-Escurra, C.5
Amaral, L.6
Van Ingen, J.7
Boeree, M.J.8
-
8
-
-
84855829764
-
Successful alternative treatment of extensively drug-resistant tuberculosis in Argentina with a combination of linezolid, moxifloxacin and thioridazine
-
Abbate E, Vescovo M, Natiello M, Cufre M, Garcia A, Gonzalez Montaner P, Ambroggi M, Ritacco V, van Soolingen D. 2012. Successful alternative treatment of extensively drug-resistant tuberculosis in Argentina with a combination of linezolid, moxifloxacin and thioridazine. J. Antimicrob. Chemother. 67:473-477. http://dx.doi.org/10.1093/jac/dkr500.
-
(2012)
J. Antimicrob. Chemother.
, vol.67
, pp. 473-477
-
-
Abbate, E.1
Vescovo, M.2
Natiello, M.3
Cufre, M.4
Garcia, A.5
Gonzalez Montaner, P.6
Ambroggi, M.7
Ritacco, V.8
Van Soolingen, D.9
-
9
-
-
84903159392
-
Reduced emergence of isoniazid resistance with concurrent use of thioridazine against acute murine tuberculosis
-
Dutta NK, Pinn ML, Karakousis PC. 2014. Reduced emergence of isoniazid resistance with concurrent use of thioridazine against acute murine tuberculosis. Antimicrob. Agents Chemother. 58:4048-4053. http://dx.doi.org/10. 1128/AAC.02981-14.
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 4048-4053
-
-
Dutta, N.K.1
Pinn, M.L.2
Karakousis, P.C.3
-
10
-
-
77956319845
-
A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising antimycobacterial thioridazine
-
Dutta NK, Mehra S, Kaushal D. 2010. A Mycobacterium tuberculosis sigma factor network responds to cell-envelope damage by the promising antimycobacterial thioridazine. PLoS One 5:e10069. http://dx.doi.org/10.1371/ journal.pone.0010069.
-
(2010)
PLoS One
, vol.5
-
-
Dutta, N.K.1
Mehra, S.2
Kaushal, D.3
-
11
-
-
79959961390
-
New patentable use of an old neuroleptic compound thioridazine to combat tuberculosis: A gene regulation perspective
-
Dutta NK, Mazumdar K, Dastidar SG, Karakousis PC, Amaral L. 2011. New patentable use of an old neuroleptic compound thioridazine to combat tuberculosis: a gene regulation perspective. Recent Pat. Antiinfect. Drug Discov. 6:128-138. http://dx.doi.org/10.2174/157489111796064597.
-
(2011)
Recent Pat. Antiinfect. Drug Discov.
, vol.6
, pp. 128-138
-
-
Dutta, N.K.1
Mazumdar, K.2
Dastidar, S.G.3
Karakousis, P.C.4
Amaral, L.5
-
12
-
-
84898622291
-
Energy metabolism and drug efflux in Mycobacterium tuberculosis
-
Black PA, Warren RM, Louw GE, van Helden PD, Victor TC, Kana BD. 2014. Energy metabolism and drug efflux in Mycobacterium tuberculosis. Antimicrob. Agents Chemother. 58:2491-2503. http://dx.doi.org/10.1128/AAC.02293-13.
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 2491-2503
-
-
Black, P.A.1
Warren, R.M.2
Louw, G.E.3
Van Helden, P.D.4
Victor, T.C.5
Kana, B.D.6
-
13
-
-
84903180280
-
Characterization of a novel necrotic granuloma model of latent tuberculosis infection and reactivation in mice
-
9 May
-
Dutta NK, Illei PB, Jain SK, Karakousis PC. 9 May 2014. Characterization of a novel necrotic granuloma model of latent tuberculosis infection and reactivation in mice. Am. J. Pathol. http://dx.doi.org/10.1016/j.ajpath.2014.03. 008.
-
(2014)
Am. J. Pathol.
-
-
Dutta, N.K.1
Illei, P.B.2
Jain, S.K.3
Karakousis, P.C.4
-
14
-
-
0026583530
-
Antagonism between isoniazid and the combination pyrazinamide-rifampin against tuberculosis infection in mice
-
Grosset J, Truffot-Pernot C, Lacroix C, Ji B. 1992. Antagonism between isoniazid and the combination pyrazinamide-rifampin against tuberculosis infection in mice. Antimicrob. Agents Chemother. 36:548-551. http://dx.doi.org/10.1128/AAC.36.3.548.
-
(1992)
Antimicrob. Agents Chemother.
, vol.36
, pp. 548-551
-
-
Grosset, J.1
Truffot-Pernot, C.2
Lacroix, C.3
Ji, B.4
-
15
-
-
0029979402
-
Preventive chemotherapy of tuberculosis in Cornell model mice with combinations of rifampin, isoniazid, and pyrazinamide
-
Dhillon J, Dickinson JM, Sole K, Mitchison DA. 1996. Preventive chemotherapy of tuberculosis in Cornell model mice with combinations of rifampin, isoniazid, and pyrazinamide. Antimicrob. Agents Chemother. 40:552-555. (Pubitemid 26076566)
-
(1996)
Antimicrobial Agents and Chemotherapy
, vol.40
, Issue.3
, pp. 552-555
-
-
Dhillon, J.1
Dickinson, J.M.2
Sole, K.3
Mitchison, D.A.4
-
16
-
-
79959935423
-
Safety and efficacy of thioridazine as salvage therapy in Indian patients with XDR-TB
-
Udwadia ZF, Sen T, Pinto LM. 2011. Safety and efficacy of thioridazine as salvage therapy in Indian patients with XDR-TB. Recent Pat. Antiinfect. Drug Discov. 6:88-91. http://dx.doi.org/10.2174/157489111796064614.
-
(2011)
Recent Pat. Antiinfect. Drug Discov.
, vol.6
, pp. 88-91
-
-
Udwadia, Z.F.1
Sen, T.2
Pinto, L.M.3
-
17
-
-
0035098674
-
Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines
-
DOI 10.1016/S0924-8579(00)00343-5, PII S0924857900003435
-
Viveiros M, Amaral L. 2001. Enhancement of antibiotic activity against poly-drug resistant Mycobacterium tuberculosis by phenothiazines. Int. J. Antimicrob. Agents 17:225-228. http://dx.doi.org/10.1016/S0924-8579(00)00343-5. (Pubitemid 32229901)
-
(2001)
International Journal of Antimicrobial Agents
, vol.17
, Issue.3
, pp. 225-228
-
-
Viveiros, M.1
Amaral, L.2
-
18
-
-
84887432659
-
Thioridazine pharmacokinetic-pharmacodynamic parameters "wobble" during treatment of tuberculosis: A theoretical basis for shorter-duration curative monotherapy with congeners
-
Musuka S, Srivastava S, Siyambalapitiyage Dona CW, Meek C, Leff R, Pasipanodya J, Gumbo T. 2013. Thioridazine pharmacokinetic-pharmacodynamic parameters "wobble" during treatment of tuberculosis: a theoretical basis for shorter-duration curative monotherapy with congeners. Antimicrob. Agents Chemother. 57:5870-5877. http://dx.doi.org/10.1128/AAC.00829-13.
-
(2013)
Antimicrob. Agents Chemother.
, vol.57
, pp. 5870-5877
-
-
Musuka, S.1
Srivastava, S.2
Siyambalapitiyage Dona, C.W.3
Meek, C.4
Leff, R.5
Pasipanodya, J.6
Gumbo, T.7
-
19
-
-
41949097208
-
Nitrate enhances the survival of Mycobacterium tuberculosis during inhibition of respiration
-
DOI 10.1128/JB.01857-07
-
Sohaskey CD. 2008. Nitrate enhances the survival of Mycobacterium tuberculosis during inhibition of respiration. J. Bacteriol. 190:2981-2986. http://dx.doi.org/10.1128/JB.01857-07. (Pubitemid 351508198)
-
(2008)
Journal of Bacteriology
, vol.190
, Issue.8
, pp. 2981-2986
-
-
Sohaskey, C.D.1
-
20
-
-
84880288729
-
Thioridazine lacks bactericidal activity in an animal model of extracellular tuberculosis
-
Dutta NK, Pinn ML, Zhao M, Rudek MA, Karakousis PC. 2013. Thioridazine lacks bactericidal activity in an animal model of extracellular tuberculosis. J. Antimicrob. Chemother. 68:1327-1330. http://dx.doi.org/10.1093/jac/dkt037.
-
(2013)
J. Antimicrob. Chemother.
, vol.68
, pp. 1327-1330
-
-
Dutta, N.K.1
Pinn, M.L.2
Zhao, M.3
Rudek, M.A.4
Karakousis, P.C.5
-
21
-
-
79959929330
-
Latent tuberculosis: Is there a role for thioridazine?
-
Sohaskey C. 2011. Latent tuberculosis: is there a role for thioridazine? Pat. Antiinfect. Drug Discov. 6:139-146. http://dx.doi.org/10.2174/ 157489111796064551.
-
(2011)
Pat. Antiinfect. Drug Discov.
, vol.6
, pp. 139-146
-
-
Sohaskey, C.1
|