The structure and specificity of the type III secretion system effector NleC suggest a DNA mimicry mechanism of substrate recognition

Biochemistry

Volumn 53, Issue 31, 2014, Pages 5131-5139

  Turco, Michelle Marian ^a   Sousa, Marcelo Carlos ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESCHERICHIA COLI; PROTEINS; SUBSTRATES; ZINC;

CLEAVAGE RATES; CLEAVAGE SITES; INFLAMMATORY RESPONSE; PATHOGENIC BACTERIUM; SEQUENCE SELECTIVITY; SUBSTRATE RECOGNITION; SUBSTRATE SPECIFICITY; TYPE III SECRETION SYSTEM;

DNA;

DNA; I KAPPA B; NLEC PROTEIN; PROTEIN P50; PROTEINASE; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR RELB; UNCLASSIFIED DRUG; ZINC;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING SITE; COMMENSAL ESCHERICHIA COLI; CRYSTALLIZATION; DNA BINDING; DNA STRUCTURE; HUMAN; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN DEGRADATION; PROTEIN DETERMINATION; PROTEIN STRUCTURE; RECOGNITION; STATIC ELECTRICITY; STEREOSPECIFICITY; TYPE III SECRETION SYSTEM;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DNA; ESCHERICHIA COLI O157; ESCHERICHIA COLI PROTEINS; HOST-PATHOGEN INTERACTIONS; HUMANS; MODELS, MOLECULAR; MOLECULAR MIMICRY; NF-KAPPA B; PROTEIN CONFORMATION; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; STATIC ELECTRICITY;

EID: 84905982937     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi500593e     Document Type: Article

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