Identification of specific antigenic epitope at N-terminal segment of enterovirus 71 (EV-71) VP1 protein and characterization of its use in recombinant form for early diagnosis of EV-71 infection

Virus Research

Volumn 189, Issue , 2014, Pages 248-253

  Zhang, Jianhua ^a,b   Jiang, Bingfu ^a   Xu, Mingjie ^a   Dai, Xing ^a   Purdy, Michael A ^c   Meng, Jihong ^a  

^a MEDICAL SCHOOL OF SOUTHEAST UNIVERSITY   (China)

^b SHAOXING UNIVERSITY   (China)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

Early diagnosis; Enterovirus 71; Hand, foot and mouth disease; Viral capsid protein

Indexed keywords

EPITOPE; HYBRID PROTEIN; PROTEIN VP1; RECOMBINANT PROTEIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; VIRUS ANTIBODY; VIRUS ANTIGEN; VIRUS PROTEIN;

ANIMAL CELL; ANTIGEN DETECTION; ARTICLE; CONTROLLED STUDY; EARLY DIAGNOSIS; ECHO VIRUS; ENTEROVIRUS 71; ENTEROVIRUS INFECTION; ENZYME LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; GENOTYPE; HUMAN; HUMAN CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN STABILITY; SEQUENCE ALIGNMENT; WESTERN BLOTTING; ADULT; ANIMAL; BLOOD; DIAGNOSTIC USE; ENTEROVIRUS; FEMALE; GENE EXPRESSION; GENETICS; HAND, FOOT AND MOUTH DISEASE; IMMUNOLOGY; INFANT; MALE; PRESCHOOL CHILD; RABBIT; SENSITIVITY AND SPECIFICITY;

ADULT; ANIMALS; ANTIBODIES, VIRAL; ANTIGENS, VIRAL; BLOTTING, WESTERN; CHILD, PRESCHOOL; CONSERVED SEQUENCE; EARLY DIAGNOSIS; ENTEROVIRUS A, HUMAN; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITOPES, B-LYMPHOCYTE; ESCHERICHIA COLI; FEMALE; GENE EXPRESSION; HAND, FOOT AND MOUTH DISEASE; HUMANS; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INFANT; MALE; RABBITS; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY; VIRAL STRUCTURAL PROTEINS;

EID: 84905981595     PISSN: 01681702     EISSN: 18727492     Source Type: Journal    
DOI: 10.1016/j.virusres.2014.06.003     Document Type: Article

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