Preventing the transmission of multidrug-resistant organisms: Modeling the relative importance of hand hygiene and environmental cleaning interventions

Infection Control and Hospital Epidemiology

Volumn 35, Issue 9, 2014, Pages 1156-1162

  Barnes, Sean L ^a   Morgan, Daniel J ^b   Harris, Anthony D ^b   Carling, Phillip C ^c   Thom, Kerri A ^b  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACINETOBACTER BAUMANNII; ARTICLE; DISEASE TRANSMISSION; ENVIRONMENTAL SANITATION; HAND WASHING; HEALTH CARE FACILITY; HUMAN; INFECTION CONTROL; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MULTIDRUG RESISTANCE; NURSE; PHYSICIAN; PROTOCOL COMPLIANCE; SIMULATION; VANCOMYCIN RESISTANT ENTEROCOCCUS; ACINETOBACTER INFECTIONS; BIOLOGICAL MODEL; COMPARATIVE STUDY; COMPUTER SIMULATION; CROSS INFECTION; DISINFECTION; EVALUATION STUDY; GRAM-POSITIVE BACTERIAL INFECTIONS; PROCEDURES; STAPHYLOCOCCAL INFECTIONS; TRANSMISSION; TREATMENT OUTCOME;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; COMPUTER SIMULATION; CROSS INFECTION; DISINFECTION; DRUG RESISTANCE, MULTIPLE, BACTERIAL; GRAM-POSITIVE BACTERIAL INFECTIONS; HAND HYGIENE; HUMANS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MODELS, BIOLOGICAL; STAPHYLOCOCCAL INFECTIONS; TREATMENT OUTCOME; VANCOMYCIN-RESISTANT ENTEROCOCCI;

EID: 84905965197     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/677632     Document Type: Article

References (21)

1. Centers for Disease Control and Prevention (CDC). Antibiotic Resistance Threats in the United States. Atlanta: CDC, 2013.
2. World Health Organization (WHO). WHO Guidelines on Hand Hygiene in Health Care. Geneva: WHO, 2009.
3. Hota B. Contamination, disinfection, and cross-colonization: are hospital surfaces reservoirs for nosocomial infection? Clin Infect Dis 2004;39(8):1182-1189.
4. Morgan DJ, Rogawski E, Thom KA, et al. Transfer of multidrugresistant bacteria to healthcare workers' gloves and gowns after patient contact increases with environmental contamination. Crit Care Med 2012;40(4):1045-1051.
5. Huang SS, Datta R, Platt R. Risk of acquiring antibiotic-resistant bacteria from prior room occupants. Arch Intern Med 2006; 166(18):1945-1951.
6. Nseir S, Blazejewski C, Lubret R, Wallet F, Courcol R, Durocher A. Risk of acquiring multidrug-resistant gram-negative bacilli from prior room occupants in the intensive care unit. Clin Microbiol Infect 2011;17(8):1201-1208.
7. Hayden MK, Blom DW, Lyle EA, Moore CG, Weinstein RA. Risk of hand or glove contamination after contact with patients colonized with vancomycin-resistant Enterococcus or the colonized patients' environment. Infect Control Hosp Epidemiol 2008; 29(2):149-154.
8. Erasmus V, Daha TJ, Brug H, et al. Systematic review of studies on compliance with hand hygiene guidelines in hospital care. Infect Control Hosp Epidemiol 2010;31(3):283-294.
9. Harris AD, Pineles L, Belton B, et al. Universal glove and gown use and acquisition of antibiotic-resistant bacteria in the ICU: a randomized trial. JAMA 2013;310(15):1571-1580.
10. Derde LP, Cooper BS, Goossens H, et al. Interventions to reduce colonisation and transmission of antimicrobial-resistant bacteria in intensive care units: an interrupted time series study and cluster randomised trial. Lancet Infect Dis 2014;14(1):31-39.
11. Carling P. Methods for assessing the adequacy of practice and improving room disinfection. Am J Infect Control 2013;41(suppl 5):S20-S25.
12. Wilensky U. NetLogo, Evanston, IL: Center for Connected Learning and Computer-Based Modeling, Northwestern University, 1999.
13. Girou E, Loyeau S, Legrand P, Oppein F, Brun-Buisson C. Ef-ficacy of handrubbing with alcohol based solution versus standard handwashing with antiseptic soap: randomised clinical trial. BMJ 2002;325:362.
14. Hornbeck T, Naylor D, Segre AM, Thomas G, Herman T, Polgreen PM. Using sensor networks to study the effect of peripatetic healthcare workers on the spread of hospital-associated infections. J Infect Dis 2012;206(10):1549-1557.
15. Datta R, Platt R, Yokoe DS, Huang SS. Environmental cleaning intervention and risk of acquiring multidrug-resistant organisms from prior room occupants. Arch Intern Med 2011;171(6):491-494.
16. Climo MW, Sepkowitz KA, Zuccotti G, et al. The effect of daily bathing with chlorhexidine on the acquisition of methicillinresistant Staphylococcus aureus, vancomycin-resistant Enterococcus, and healthcare-associated bloodstream infections: results of a quasi-experimental multicenter trial. Crit Care Med 2009; 37(6):1858-1865.
17. Huskins WC, Huckabee CM, O'Grady NP, et al. Intervention to reduce transmission of resistant bacteria in intensive care. N Engl J Med 2011;364(15):1407-1418.
18. Morgan DJ, Pineles LL, Shardell M, et al. The effect of contact precautions on healthcare worker activity in acute care hospitals. Infect Control Hosp Epidemiol 2013;31(1):69-73.
19. Hayden MK, Bonten MJ, Blom DW, Lyle EA, van de Vijver DA, Weinstein RA. Reduction in acquisition of vancomycin-resistant Enterococcus after enforcement of routine environmental cleaning measures. Clin Infect Dis 2006;42(11):1552-1560.
20. Carling PC, Parry MM, Rupp ME, et al. Improving cleaning of the environment surrounding patients in 36 acute care hospitals. Infect Control Hosp Epidemiol 2008;29(11):1035-1041.
21. Goodman ER, Platt R, Bass R, Onderdonk AB, Yokoe DS, Huang SS. Impact of an environmental cleaning intervention on the presence of methicillin-resistant Staphylococcus aureus and vancomycin- resistant enterococci on surfaces in intensive care unit rooms. Infect Control Hosp Epidemiol 2008;29(7):593-599.