Wnt/β-catenin signalling maintains self-renewal and tumourigenicity of head and neck squamous cell carcinoma stem-like cells by activating Oct4

Journal of Pathology

Volumn 234, Issue 1, 2014, Pages 99-107

  Lee, Sang Hyuk ^a   Koo, Bon Seok ^b   Kim, Jin Man ^b   Huang, Songmei ^b   Rho, Young Soo ^c   Bae, Woo Jin ^d   Kang, Hyun Jung ^e   Kim, Young Sook ^e   Moon, Jung Hwa ^e   Lim, Young Chang ^e  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Chungnam National University College of Medicine   (South Korea)

^c Ewha Womans University School of Medicine   (South Korea)

^d Hallym University College of Medicine   (South Korea)

^e Konkuk University School of Medicine   (South Korea)

Author keywords

cancer stem cells; head and neck cancer; Oct4; target therapy; Wnt catenin signalling

Indexed keywords

BETA CATENIN; CYCLIN D1; HERMES ANTIGEN; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 1; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 2; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 3; MULTIDRUG RESISTANCE ASSOCIATED PROTEIN 4; MULTIDRUG RESISTANCE PROTEIN 5; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; SHORT HAIRPIN RNA; TRANSCRIPTION FACTOR SOX4; WNT PROTEIN; POU5F1 PROTEIN, HUMAN; SMALL INTERFERING RNA;

ARTICLE; CANCER INHIBITION; CANCER PROGNOSIS; CANCER STEM CELL; CANCER SURVIVAL; CARCINOGENICITY; CELL DEDIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE SPECIFIC SURVIVAL; FROZEN SECTION; GENE EXPRESSION; GENE REPRESSION; HEAD AND NECK SQUAMOUS CELL CARCINOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; OVERALL SURVIVAL; PHENOTYPE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM LIKE CELL; TRANSCRIPTION REGULATION; CARCINOGENESIS; CARCINOMA, SQUAMOUS CELL; CELL TRANSFORMATION; GENE EXPRESSION REGULATION; GENETICS; HEAD AND NECK NEOPLASMS; METABOLISM; PATHOLOGY; STEM CELL; TUMOR CELL LINE; WNT SIGNALING PATHWAY;

BETA CATENIN; CARCINOGENESIS; CARCINOMA, SQUAMOUS CELL; CELL DEDIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAD AND NECK NEOPLASMS; HUMANS; NEOPLASTIC STEM CELLS; OCTAMER TRANSCRIPTION FACTOR-3; RNA, SMALL INTERFERING; STEM CELLS; WNT PROTEINS; WNT SIGNALING PATHWAY;

EID: 84905913415     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4383     Document Type: Article

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