Outcomes in locally advanced rectal cancer with highly selective preoperative chemoradiotherapy

British Journal of Surgery

Volumn 101, Issue 10, 2014, Pages 1290-1298

  Williamson, J S ^a   Jones, H G ^a   Davies, M ^a   Evans, M D ^a   Hatcher, O ^a   Beynon, J ^a   Harris, D A ^a  

^a SINGLETON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADJUVANT CHEMORADIOTHERAPY; ADJUVANT THERAPY; ADULT; AGED; ARTICLE; COMPARATIVE STUDY; FEMALE; HUMAN; KAPLAN MEIER METHOD; MALE; METHODOLOGY; MIDDLE AGED; MORTALITY; PATHOLOGY; PREOPERATIVE CARE; RADIATION DOSE; RECTUM TUMOR; RETROSPECTIVE STUDY; TREATMENT OUTCOME; TUMOR RECURRENCE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; CHEMORADIOTHERAPY, ADJUVANT; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; NEOPLASM RECURRENCE, LOCAL; PREOPERATIVE CARE; RADIOTHERAPY DOSAGE; RECTAL NEOPLASMS; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 84905902986     PISSN: 00071323     EISSN: 13652168     Source Type: Journal    
DOI: 10.1002/bjs.9570     Document Type: Article

References (37)

1. Sebag-Montefiore D, Stephens RJ, Steele R, Monson J, Grieve R, Khanna S, et al., Preoperative radiotherapy versus selective postoperative chemoradiotherapy in patients with rectal cancer (MRC CR07 and NCIC-CTG C016): a multicentre, randomised trial. Lancet 2009; 373: 811-820.
2. Sauer R, Becker H, Hohenberger W, Rodel C, Wittekind C, Fietkau R, et al.,; German Rectal Cancer Study Group. Preoperative versus postoperative chemoradiotherapy for rectal cancer. N Engl J Med 2004; 351: 1731-1740.
3. Peeters KC, Marijnen CA, Nagtegaal ID, Kranenbarg EK, Putter H, Wiggers T, et al.,; Dutch Colorectal Cancer Group. The TME trial after a median follow-up of 6 years: increased local control but no survival benefit in irradiated patients with resectable rectal carcinoma. Ann Surg 2007; 246: 693-701.
4. De Caluwé L, Van Nieuwenhove Y, Ceelen WP,. Preoperative chemoradiation versus radiation alone for stage II and III resectable rectal cancer. Cochrane Database Syst Rev 2013; (2)CD006041.
5. Cancer National Specialist Advisory Group. Wales Bowel Cancer Audit Report for Patients Diagnosed April 2009-March 2010 and August 2010-July 2011; 2013. http://www.wales.nhs.uk/sites3/Documents/322/ Welsh%20Bowel%20Cancer%20Audit-2009-11-.pdf [accessed 20 March 2014].
6. Augestad KM, Lindsetmo RO, Stulberg J, Reynolds H, Senagore A, Champagne B, et al.,; International Rectal Cancer Study Group (IRCSG). International preoperative rectal cancer management: staging, neoadjuvant treatment, and impact of multidisciplinary teams. World J Surg 2010; 34: 2689-2700.
7. Bruheim K, Guren MG, Skovlund E, Hjermstad MJ, Dahl O, Frykholm G, et al., Late side effects and quality of life after radiotherapy for rectal cancer. Int J Radiat Oncol Biol Phys 2010; 76: 1005-1011.
8. Rothenberger DA, Akbari R, Baxter NN,. Are we overtreating some patients with rectal cancer? Oncology (Williston Park) 2004; 18: 1789-1796.
9. Merkel S, Weber K, Schellerer V, Göhl J, Fietkau R, Agaimy A, et al., Prognostic subdivision of ypT3 rectal tumours according to extension beyond the muscularis propria. Br J Surg 2014; 101: 566-572.
10. Taylor FG, Quirke P, Heald RJ, Moran B, Blomqvist L, Swift I, et al.,; MERCURY study group. Preoperative high-resolution magnetic resonance imaging can identify good prognosis stage I, II, and III rectal cancer best managed by surgery alone: a prospective, multicenter, European study. Ann Surg 2011; 253: 711-719.
11. Gunderson LL, Callister M, Marschke R, Young-Fadok T, Heppell J, Efron J,. Stratification of rectal cancer stage for selection of postoperative chemoradiotherapy: current status. Gastrointest Cancer Res 2008; 2: 25-33.
12. Mathis KL, Larson DW, Dozois EJ, Cima RR, Huebner M, Haddock MG, et al., Outcomes following surgery without radiotherapy for rectal cancer. Br J Surg 2012; 99: 137-143.
13. Simunovic M, Jacob S, Coates AJ, Vogt K, Moran BJ, Heald RJ,. Outcomes following a limited approach to radiotherapy in rectal cancer. Br J Surg 2011; 98: 1483-1488.
14. Wibe A, Law WL, Fazio V, Delaney CP,. Tailored rectal cancer treatment-a time for implementing contemporary prognostic factors? Colorectal Dis 2013; 15: 1333-1342.
15. Glynne-Jones R, Harrison M, Hughes R,. Challenges in the neoadjuvant treatment of rectal cancer: balancing the risk of recurrence and quality of life. Cancer Radiother 2013; 17: 675-685.
16. Quirke P, Steele R, Monson J, Grieve R, Khanna S, Couture J, et al.,; MRC CR07/NCIC-CTG CO16 Trial Investigators; NCRI Colorectal Cancer Study Group. Effect of the plane of surgery achieved on local recurrence in patients with operable rectal cancer: a prospective study using data from the MRC CR07 and NCIC-CTG CO16 randomised clinical trial. Lancet 2009; 373: 821-828.
17. Fernández E,; STROBE Group. [ Observational studies in epidemiology (STROBE).] Med Clin (Barc) 2005; 125: 43-48.
18. National Institute for Health and Clinical Excellence (NICE). Colorectal Cancer: the Diagnosis and Management of Colorectal Cancer. NICE clinical guideline 131; 2011. http://www.nice.org.uk/nicemedia/live/13597/56998/56998.pdf [accessed 20 March 2014].
19. Ernest-Miles W., A method of performing abdomino-perineal excision for carcinoma of the rectum and of the terminal portion of the pelvic colon. Lancet 1908; 172: 1812.
20. Mulsow J, Winter DC,. Extralevator abdominoperineal resection for low rectal cancer: new direction or miles behind? Arch Surg 2010; 145: 811-813.
21. Kaplan E, Meier P,. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958; 53: 457-481.
22. Stricker D., BrightStat.com: free statistics online. Comput Methods Programs Biomed 2008; 92: 135-143.
23. Hanly AM, Ryan EM, Rogers AC, McNamara DA, Madoff RD, Winter DC,. Multicenter Evaluation of Rectal cancer ReImaging pOst Neoadjuvant (MERRION) Therapy. Ann Surg 2014; 259: 723-727.
24. Adam IJ, Mohamdee MO, Martin IG, Scott N, Finan PJ, Johnston D, et al., Role of circumferential margin involvement in the local recurrence of rectal cancer. Lancet 1994; 344: 707-711.
25. Marijnen CA, Nagtegaal ID, Kapiteijn E, Kranenbarg EK, Noordijk EM, van Krieken JH, et al.; Cooperative investigators of the Dutch Colerectal Cancer Group. Radiotherapy does not compensate for positive resection margins in rectal cancer patients: report of a multicenter randomized trial. Int J Radiat Oncol Biol Phys 2003; 55: 1311-1320.
26. Scott NA, Susnerwala S, Gollins S, Myint AS, Levine E,. Preoperative neo-adjuvant therapy for curable rectal cancer-reaching a consensus 2008. Colorectal Dis 2009; 11: 245-248.
27. Glynne-Jones R., The future of rectal cancer: let's do the right trials. J Clin Oncol 2011; 29: 4057-4059.
28. Cox JD, Stetz J, Pajak TF,. Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC). Int J Radiat Oncol Biol Phys 1995; 31: 1341-1346.
29. Suppiah A, Hartley JE, Monson JR,. Advances in radiotherapy in operable rectal cancer. Dig Surg 2009; 26: 187-199.
30. Marijnen CA, Kapiteijn E, van de Velde CJ, Martijn H, Steup WH, Wiggers T, et al., Acute side effects and complications after short-term preoperative radiotherapy combined with total mesorectal excision in primary rectal cancer: report of a multicenter randomized trial. J Clin Oncol 2002; 20: 817-825.
31. Peeters KC, van de Velde CJ, Leer JW, Martijn H, Junggeburt JM, Kranenbarg EK, et al., Late side effects of short-course preoperative radiotherapy combined with total mesorectal excision for rectal cancer: increased bowel dysfunction in irradiated patients-a Dutch colorectal cancer group study. J Clin Oncol 2005; 23: 6199-6206.
32. Prabhudesai AG, Cornes P, Glees JP, Kumar D,. Long-term morbidity following short-course, pre-operative radiotherapy and total mesorectal excision for rectal cancer. Surgeon 2005; 3: 347-351.
33. Swellengrebel HA, Marijnen CA, Verwaal VJ, Vincent A, Heuff G, Gerhards MF, et al., Toxicity and complications of preoperative chemoradiotherapy for locally advanced rectal cancer. Br J Surg 2011; 98: 418-426.
34. Kunkler IH, Prescott RJ, Williams LJ, King CC,. When may adjuvant radiotherapy be avoided in operable breast cancer? Clin Oncol (R Coll Radiol) 2006; 18: 191-199.
35. Wibe A, Syse A, Andersen E, Tretli S, Myrvold HE, Søreide O,; Norwegian Rectal Cancer Group. Oncological outcomes after total mesorectal excision for cure for cancer of the lower rectum: anterior vs. abdominoperineal resection. Dis Colon Rectum 2004; 47: 48-58.
36. Kennelly RP, Rogers AC, Winter DC,; Abdominoperineal Excision Study Group. Multicentre study of circumferential margin positivity and outcomes following abdominoperineal excision for rectal cancer. Br J Surg 2013; 100: 160-166.
37. Anderin C, Martling A, Lagergren J, Ljung A, Holm T,. Short-term outcome after gluteus maximus myocutaneous flap reconstruction of the pelvic floor following extra-levator abdominoperineal excision of the rectum. Colorectal Dis 2012; 14: 1060-1064.