Drug Intervention Response Predictions with PARADIGM (DIRPP) identifies drug resistant cancer cell lines and pathway mechanisms of resistance

Pacific Symposium on Biocomputing

Volumn , Issue , 2014, Pages 125-135

  Brubaker, Douglas ^a   Difeo, Analisa ^a   Chen, Yanwen ^a   Pearl, Taylor ^c   Zhai, Kaide ^a   Bebek, Gurkan ^a,b   Chance, Mark ^a   Barnholtz Sloan, Jill ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DATA INTEGRATION; DISEASES; FORECASTING; PIPELINES; TUMORS;

ACCURACY AND PRECISION; CELLULAR RESPONSE; GENE EXPRESSION DATA; INTERVENTION RESPONSE; MECHANISMS OF RESISTANCES; MOLECULAR MECHANISM; PROBABILISTIC GRAPHICAL MODELS; RECOGNITION ALGORITHM;

GENE EXPRESSION;

ALGORITHM; ARTICLE; BIOLOGICAL MODEL; BIOLOGY; BREAST TUMOR; DRUG DATABASE; DRUG DEVELOPMENT; DRUG RESISTANCE; ENDOMETRIUM TUMOR; FEMALE; GENETIC DATABASE; GENETICS; HUMAN; METABOLISM; NEOPLASM; OVARY TUMOR; STATISTICAL MODEL; STATISTICS; TUMOR CELL LINE;

ALGORITHMS; BREAST NEOPLASMS; CELL LINE, TUMOR; COMPUTATIONAL BIOLOGY; DATABASES, GENETIC; DATABASES, PHARMACEUTICAL; DRUG DISCOVERY; DRUG RESISTANCE, NEOPLASM; ENDOMETRIAL NEOPLASMS; FEMALE; HUMANS; MODELS, GENETIC; MODELS, STATISTICAL; NEOPLASMS; OVARIAN NEOPLASMS;

EID: 84905871217     PISSN: 23356928     EISSN: 23356936     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (21)

1. TCGA. Nat. 497:67-73 (2013)
2. TCGA. Nat. 474:609-615 (2011)
3. TCGA. Nat. 490:61-70 (2012)
4. Garnett, M. J., et al., Nat. 483(7391):570-575. (2012).
5. Barretina, J. et al., Nat. 483(7391):603-607 (2012)
6. Subramaian, A. et al., PNAS. 102:15545-15550 (2005)
7. Vaske, C. J. et al., Bioinf. 26:i237-i247 (2010)
8. Ng, S. et al,. Bioinf. 28:i640-i646 (2012)
9. Varadan, V. et al.., IEEE Sig. Proc. 35-49 (2011)
10. Nibbe, R. K. et al., PLOS Comp. Bio. 6 (1) (2009)
11. Nibbe, R. K. et al., Journal of Comp. Bio. 18 (3) 263-281 (2010)
12. Papillon-Cavanagh, S, et al., J Am Med Inform Assoc. 20:597-602 (2013)
13. Napolitano, F. et al., Journal of Chemiinformatics. 5:30 (2013)
14. McCarthy, J. J. et al., Science Translational Med. 5(189):1-17 (2013)
15. Heiser, L. M. et al., PNAS. 109:2724-2729 (2011)
16. Knox C. et al., Nucleic Acids Res. 39(Database issue):D1035-41. PMID: 21059682 (2011)
17. Wishart DS. et al., Nucleic Acids Res. 36(Database issue):D901-6. PMID: 18048412 (2008)
18. Wishart DS. et al. Nucleic Acids Res. 34(Database issue):D668-72. PMID: 16381955 (2006)
19. Domcke, S. et al. Nat. Commun. 4:2126 doi: 10.1038/ncomms3126 (2013)
20. Isonishi, S. et al. Oncology Reports. 18(1):195-201 (2007)
21. Weigel, M. T. et al. Annals of Oncology. 24(1):126-133. doi:10.1093/annonc/mds240 (2013)