The protease inhibitor HAI-2, but not HAI-1, regulates matriptase activation and shedding through prostasin

Journal of Biological Chemistry

Volumn 289, Issue 32, 2014, Pages 22319-22332

  Friis, Stine ^a,c   Sales, Katiuchia Uzzun ^a,b   Schafer, Jeffrey Martin ^a,d   Vogel, Lotte K ^c   Kataoka, Hiroaki ^e   Bugge, Thomas H ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

^b NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

^d THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^e UNIVERSITY OF MIYAZAKI   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES;

CELL SURFACE EXPRESSION; HEPATOCYTE GROWTH FACTOR; IN-VITRO; IN-VIVO; MATRIPTASE; PROTEASE INHIBITOR;

CHEMICAL ACTIVATION;

HAI-2 PROTEIN, MOUSE; LEUKOCYTE ELASTASE INHIBITOR; MATRIPTASE; MEMBRANE PROTEIN; PROSTASIN; SERINE PROTEINASE; SERINE PROTEINASE INHIBITOR; SMALL INTERFERING RNA; SPINT1 PROTEIN, HUMAN; SPINT1 PROTEIN, MOUSE; SPINT2 PROTEIN, HUMAN;

129 MOUSE; ANIMAL; C57BL MOUSE; CACO 2 CELL LINE; ENZYME ACTIVATION; GENE SILENCING; GENETICS; HUMAN; INTESTINE MUCOSA; METABOLISM; MOUSE; TRANSGENIC MOUSE;

ANIMALS; CACO-2 CELLS; ENZYME ACTIVATION; GENE SILENCING; HUMANS; INTESTINAL MUCOSA; MEMBRANE GLYCOPROTEINS; MEMBRANE PROTEINS; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC; PROTEINASE INHIBITORY PROTEINS, SECRETORY; RNA, SMALL INTERFERING; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS;

EID: 84905860585     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.574400     Document Type: Article

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